HK1065722A1 - Cpg plus oil in water emulsion as adjuvant system for truncated bovine herpesvirus-1 glycoprotein d cpg 1 d - Google Patents
Cpg plus oil in water emulsion as adjuvant system for truncated bovine herpesvirus-1 glycoprotein d cpg 1 dInfo
- Publication number
- HK1065722A1 HK1065722A1 HK04108725.1A HK04108725A HK1065722A1 HK 1065722 A1 HK1065722 A1 HK 1065722A1 HK 04108725 A HK04108725 A HK 04108725A HK 1065722 A1 HK1065722 A1 HK 1065722A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- cpg
- glycoprotein
- water emulsion
- adjuvant system
- bovine herpesvirus
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7088—Compounds having three or more nucleosides or nucleotides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/245—Herpetoviridae, e.g. herpes simplex virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55561—CpG containing adjuvants; Oligonucleotide containing adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16734—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Mycology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Dispersion Chemistry (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32773401P | 2001-10-06 | 2001-10-06 | |
PCT/EP2002/011206 WO2003030934A2 (fr) | 2001-10-06 | 2002-10-07 | Formulations cpg et procedes y relatifs |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1065722A1 true HK1065722A1 (en) | 2005-03-04 |
Family
ID=23277807
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK04108725.1A HK1065722A1 (en) | 2001-10-06 | 2004-11-05 | Cpg plus oil in water emulsion as adjuvant system for truncated bovine herpesvirus-1 glycoprotein d cpg 1 d |
Country Status (9)
Country | Link |
---|---|
US (1) | US20050238660A1 (fr) |
EP (1) | EP1434602B1 (fr) |
JP (1) | JP2005508945A (fr) |
KR (1) | KR20050048539A (fr) |
CN (1) | CN100438908C (fr) |
AU (1) | AU2002347062B2 (fr) |
CA (1) | CA2471968C (fr) |
HK (1) | HK1065722A1 (fr) |
WO (1) | WO2003030934A2 (fr) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6207646B1 (en) | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
US6406705B1 (en) | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
EP1077722B1 (fr) | 1998-05-22 | 2006-08-09 | Ottawa Health Research Institute | Methodes et produits permettant d'induire une immunite au niveau des muqueuses |
DK1104306T3 (da) * | 1998-08-10 | 2006-05-22 | Antigenics Inc | Præparater af CpG- og saponinadjuvanser og fremgangsmåder til anvendelse deraf |
AR040996A1 (es) * | 2002-08-19 | 2005-04-27 | Coley Pharm Group Inc | Acidos nucleicos inmunoestimuladores |
JP2006512927A (ja) | 2002-12-11 | 2006-04-20 | コーリー ファーマシューティカル グループ,インコーポレイテッド | 5’cpg核酸およびその使用方法 |
WO2004087203A2 (fr) * | 2003-04-02 | 2004-10-14 | Coley Pharmaceutical Group, Ltd. | Formulations de type huile-dans-l'eau a base d'acides nucleiques immunostimulateurs, et procedes d'utilisation associes |
JP4629964B2 (ja) * | 2003-09-12 | 2011-02-09 | 株式会社林原生物化学研究所 | ウシの消化器疾患治療剤 |
US8148341B2 (en) * | 2005-07-01 | 2012-04-03 | Index Pharmaceuticals Ab | Method for modulating responsiveness to steroids |
ES2349617T3 (es) * | 2005-07-01 | 2011-01-07 | Index Pharmaceuticals Ab | Método inmunoestimulante. |
JP2009513629A (ja) * | 2005-10-28 | 2009-04-02 | インデックス・ファーマシューティカルズ・アクチエボラーグ | 炎症性疾患を予防、処置、および/または緩和する組成物および方法 |
US10138279B2 (en) | 2006-04-13 | 2018-11-27 | Regents Of The University Of Michigan | Compositions and methods for Bacillus anthracis vaccination |
JP2010525063A (ja) * | 2007-04-27 | 2010-07-22 | キメリクス,インコーポレイテッド | ヌクレオシドホスホナートが投与された被験者における腎毒性を減少させる方法 |
AU2008276451A1 (en) * | 2007-07-17 | 2009-01-22 | Zalicus Inc. | Treatments of B-cell proliferative disorders |
WO2009011897A1 (fr) * | 2007-07-17 | 2009-01-22 | Combinatorx, Incorporated | Combinaisons pour le traitement des troubles prolifératifs des lymphocytes b |
CN105055432A (zh) | 2008-01-25 | 2015-11-18 | 奇默里克斯公司 | 治疗病毒感染的方法 |
CN101559224B (zh) * | 2008-04-18 | 2012-07-11 | 北京生物制品研究所 | 脊髓灰质炎疫苗 |
CA2725381A1 (fr) * | 2008-05-23 | 2010-03-25 | The Regents Of The University Of Michigan | Adjuvants de nanoemulsion |
US9415006B2 (en) * | 2008-05-23 | 2016-08-16 | The Regents Of The University Of Michigan | Immunogenic compositions comprising nanoemulsion and hepatitis B virus immunogen and methods of using the same |
WO2009151569A2 (fr) * | 2008-06-09 | 2009-12-17 | Combinatorx, Incorporated | Agonistes des récepteurs bêta-adrénergiques utilisables pour le traitement des troubles prolifératifs des lymphocytes b |
WO2009156960A2 (fr) | 2008-06-27 | 2009-12-30 | Pfizer Inc. | Nouvelles compositions d'adjuvants |
TWI351288B (en) * | 2008-07-04 | 2011-11-01 | Univ Nat Pingtung Sci & Tech | Cpg dna adjuvant in avian vaccines |
EP2687209A1 (fr) | 2008-09-19 | 2014-01-22 | Nestec S.A. | Soutien nutritionnel pour prévenir et/ou atténuer la toxicité sur la moelle osseuse due à une tumeur cancéreuse |
CN102164595A (zh) * | 2008-09-19 | 2011-08-24 | 雀巢产品技术援助有限公司 | 抗癌治疗中的免疫系统营养支持 |
JP5722782B2 (ja) | 2008-09-26 | 2015-05-27 | ナノバイオ コーポレーション | ナノエマルジョン治療用組成物及びその使用方法 |
WO2010043039A1 (fr) | 2008-10-16 | 2010-04-22 | University Of Saskatchewan | Formulation d’adjuvant de combinaison |
US8394384B2 (en) | 2008-11-28 | 2013-03-12 | Merial Limited | Recombinant avian influenza vaccine and uses thereof |
EP2442827B1 (fr) | 2009-06-16 | 2016-01-06 | The Regents of the University of Michigan | Vaccins en nano-émulsion |
EP3216789A1 (fr) | 2010-02-12 | 2017-09-13 | Chimerix, Inc. | Procédés de traitement d'une infection virale |
US20110229512A1 (en) * | 2010-03-19 | 2011-09-22 | The Regents Of The University Of Michigan | Compositions and methods for diagnosing and treating urinary tract infections |
EP2563367A4 (fr) | 2010-04-26 | 2013-12-04 | Chimerix Inc | Méthodes de traitement d'infections rétrovirales et régimes posologiques associés |
US8658603B2 (en) | 2010-06-16 | 2014-02-25 | The Regents Of The University Of Michigan | Compositions and methods for inducing an immune response |
BR112015009229B1 (pt) | 2012-10-24 | 2021-07-20 | Platelet Targeted Therapeutics, Llc | Composição tendo como alvo a expressão de genes para plaquetas, uso de uma célula tronco compreendendo a referida composição para tratar hemofilia e método in vitro ou ex vivo para gerar uma célula tronco modificada |
CN103127501A (zh) * | 2013-03-27 | 2013-06-05 | 南京农业大学 | 一种用于鸡禽流感鼻腔免疫的人工合成佐剂 |
JP6586083B2 (ja) | 2013-09-19 | 2019-10-02 | ゾエティス・サービシーズ・エルエルシー | 油性アジュバント |
CA2928700C (fr) | 2013-11-01 | 2019-01-15 | University Of Oslo | Variants d'albumine et utilisations de ceux-ci |
CA2929126C (fr) | 2013-11-13 | 2020-01-07 | University Of Oslo | Vesicules de membrane externe et utilisation associees |
US11452767B2 (en) | 2013-11-15 | 2022-09-27 | Oslo Universitetssykehus Hf | CTL peptide epitopes and antigen-specific t cells, methods for their discovery, and uses thereof |
JP7158853B2 (ja) | 2014-10-10 | 2022-10-24 | ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン | 対象における食物アレルギーまたは呼吸器アレルギーを処置するための、かつ上記対象の鼻腔内に投与するための免疫原性組成物 |
KR20170097116A (ko) | 2015-01-16 | 2017-08-25 | 조에티스 서비시즈 엘엘씨 | 구제역 백신 |
EP4226936A3 (fr) | 2015-03-05 | 2023-09-27 | Northwestern University | Virus non neuro-invasifs et leurs utilisations |
GB201509431D0 (en) * | 2015-06-01 | 2015-07-15 | Equigerminal Sa | Antiviral composition |
TN2018000301A1 (en) | 2016-03-14 | 2020-01-16 | Univ Oslo | Engineered immunoglobulins with altered fcrn binding |
WO2017158421A1 (fr) | 2016-03-14 | 2017-09-21 | University Of Oslo | Immunoglobulines anti-virales synthétiques |
US11173207B2 (en) | 2016-05-19 | 2021-11-16 | The Regents Of The University Of Michigan | Adjuvant compositions |
WO2017221072A2 (fr) | 2016-06-21 | 2017-12-28 | University Of Oslo | Fragments de vaccin de liaison à hla et leurs utilisations |
WO2018096396A1 (fr) | 2016-11-22 | 2018-05-31 | University Of Oslo | Variants d'albumine et leurs utilisations |
US12005112B2 (en) | 2017-09-07 | 2024-06-11 | University Of Oslo | Vaccine molecules |
WO2019048928A1 (fr) | 2017-09-07 | 2019-03-14 | University Of Oslo | Molécules de vaccin |
CN110218729B (zh) * | 2019-05-07 | 2023-06-20 | 华南农业大学 | 一种鸡特异性免疫活化剂CpG-ODN及其应用 |
US20240156935A1 (en) | 2021-03-31 | 2024-05-16 | Vib Vzw | Vaccine Compositions for Trypanosomatids |
EP4108771A1 (fr) * | 2021-06-24 | 2022-12-28 | Johann-Wolfgang-Goethe-Universität Frankfurt am Main | Oligonucléotides contenant un quadruplex g pour le traitement préventif et thérapeutique |
CN114469913B (zh) * | 2022-02-17 | 2024-03-22 | 中国农业科学院哈尔滨兽医研究所(中国动物卫生与流行病学中心哈尔滨分中心) | Tilorone用于预防/治疗非洲猪瘟病毒感染的应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4469863A (en) | 1980-11-12 | 1984-09-04 | Ts O Paul O P | Nonionic nucleic acid alkyl and aryl phosphonates and processes for manufacture and use thereof |
US4973307A (en) | 1981-07-13 | 1990-11-27 | Alza Corporation | Method for administering drugs to a patient |
US5250028A (en) | 1989-02-15 | 1993-10-05 | Alza Corporation | Intravenous system for delivering a beneficial agent using permeability enhancers |
US6656477B1 (en) * | 1992-07-28 | 2003-12-02 | Board Of Trustees Of Michigan State University | 43 Kd protein vaccine and method for the production thereof |
US5951988A (en) * | 1993-03-30 | 1999-09-14 | University Of Saskatchewan | Adjuvant formulation with enhanced immunogenic activity, and related compositions and methods |
US6207646B1 (en) * | 1994-07-15 | 2001-03-27 | University Of Iowa Research Foundation | Immunostimulatory nucleic acid molecules |
EP1005368B1 (fr) * | 1997-03-10 | 2009-09-02 | Ottawa Hospital Research Institute | Utilisation d'acides nucléiques contenat un dinucléotide CpG non-methylé combiné avec de l'aluminium en tant qu'adjuvants |
US6406705B1 (en) * | 1997-03-10 | 2002-06-18 | University Of Iowa Research Foundation | Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant |
WO1998040097A2 (fr) * | 1997-03-10 | 1998-09-17 | Bayer Corporation | Coronavirus respiratoire bovin utilise comme vaccin |
HUP0101047A3 (en) * | 1998-03-09 | 2004-10-28 | Smithkline Beecham Biolog | Combined vaccine compositions |
JP2003524586A (ja) * | 1998-05-21 | 2003-08-19 | アイシス・ファーマシューティカルス・インコーポレーテッド | オリゴヌクレオチドの非−非経口投与のための組成物と方法 |
FR2783170B1 (fr) * | 1998-09-11 | 2004-07-16 | Pasteur Merieux Serums Vacc | Emulsion immunostimulante |
EP2286792A1 (fr) * | 1999-02-26 | 2011-02-23 | Novartis Vaccines and Diagnostics, Inc. | Microemulsions avec une surface adsorbante, comprenant une émulsion de microgouttes |
JP4812942B2 (ja) * | 1999-02-26 | 2011-11-09 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル | CGモチーフを含むオリゴヌクレオチドを用いるNeisseria抗原殺菌活性の増強 |
DK1187629T3 (da) * | 1999-04-19 | 2005-01-17 | Glaxosmithkline Biolog Sa | Adjuvanssammensætning omfattende saponin og et immunostimulerende oligonucleotid |
US20020156033A1 (en) * | 2000-03-03 | 2002-10-24 | Bratzler Robert L. | Immunostimulatory nucleic acids and cancer medicament combination therapy for the treatment of cancer |
US7157437B2 (en) * | 2000-03-10 | 2007-01-02 | Dynavax Technologies Corporation | Methods of ameliorating symptoms of herpes infection using immunomodulatory polynucleotide sequences |
US20030050268A1 (en) * | 2001-03-29 | 2003-03-13 | Krieg Arthur M. | Immunostimulatory nucleic acid for treatment of non-allergic inflammatory diseases |
-
2002
- 2002-10-07 EP EP02782841.7A patent/EP1434602B1/fr not_active Expired - Lifetime
- 2002-10-07 CN CNB028227158A patent/CN100438908C/zh not_active Expired - Lifetime
- 2002-10-07 US US10/492,002 patent/US20050238660A1/en not_active Abandoned
- 2002-10-07 AU AU2002347062A patent/AU2002347062B2/en not_active Expired
- 2002-10-07 WO PCT/EP2002/011206 patent/WO2003030934A2/fr active Application Filing
- 2002-10-07 KR KR1020047005029A patent/KR20050048539A/ko not_active Application Discontinuation
- 2002-10-07 JP JP2003533965A patent/JP2005508945A/ja active Pending
- 2002-10-07 CA CA2471968A patent/CA2471968C/fr not_active Expired - Lifetime
-
2004
- 2004-11-05 HK HK04108725.1A patent/HK1065722A1/xx not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1434602A2 (fr) | 2004-07-07 |
CN1671414A (zh) | 2005-09-21 |
WO2003030934A2 (fr) | 2003-04-17 |
WO2003030934A3 (fr) | 2003-11-06 |
KR20050048539A (ko) | 2005-05-24 |
EP1434602B1 (fr) | 2014-12-17 |
CA2471968C (fr) | 2013-07-23 |
CA2471968A1 (fr) | 2003-04-17 |
US20050238660A1 (en) | 2005-10-27 |
JP2005508945A (ja) | 2005-04-07 |
CN100438908C (zh) | 2008-12-03 |
AU2002347062B2 (en) | 2008-06-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
HK1065722A1 (en) | Cpg plus oil in water emulsion as adjuvant system for truncated bovine herpesvirus-1 glycoprotein d cpg 1 d | |
EG22812A (en) | Depwater intervention system | |
PL337488A1 (en) | Oil-in-water type compositions for vaccines | |
SG96620A1 (en) | Health maintenance system | |
IL146174A0 (en) | Confocal wafer-inspection system | |
GR3034300T3 (en) | Iso-tridecanolalkoxylates in block form as low-foam or antifoaming surfactants | |
EP0985044A4 (fr) | Vaccin anticancereux | |
GB0016196D0 (en) | Oil system | |
GB2367471B (en) | Graphics system | |
GB0027724D0 (en) | "System" | |
PL359848A1 (en) | Composition suitable for preparing an oil in water emulsion | |
HK1055604A1 (en) | Surfactant system | |
GB0116652D0 (en) | De-icing system | |
GB2375721B (en) | Water conditioning system | |
GB2361137B (en) | Scanning system | |
GB0107144D0 (en) | Water circulation system | |
AU2002343509A8 (en) | Debris removal system | |
GB9724962D0 (en) | Improvements in or relating to document platforms | |
GB0122483D0 (en) | High level maintenance safety system | |
GB2360838B (en) | Cooling system expansion tank | |
AU7451801A (en) | Account settling system | |
GB2379634B (en) | Greetings card support | |
GB0017250D0 (en) | Flooring system | |
GB0012292D0 (en) | Improvements in or relating to command systems | |
GB0109376D0 (en) | Waste water heat recovery system |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PE | Patent expired |
Effective date: 20221010 |