HK1054502A1 - Compositions for the treatment of cancer comprising a topoisomerase inhibitor and thalidomide - Google Patents

Compositions for the treatment of cancer comprising a topoisomerase inhibitor and thalidomide

Info

Publication number
HK1054502A1
HK1054502A1 HK03106199A HK03106199A HK1054502A1 HK 1054502 A1 HK1054502 A1 HK 1054502A1 HK 03106199 A HK03106199 A HK 03106199A HK 03106199 A HK03106199 A HK 03106199A HK 1054502 A1 HK1054502 A1 HK 1054502A1
Authority
HK
Hong Kong
Prior art keywords
thalidomide
cancer
treatment
compositions
administration
Prior art date
Application number
HK03106199A
Other languages
English (en)
Inventor
Jerome B Zeldis
Andrew Zeitlin
Sol Barer
Original Assignee
Celgene Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp filed Critical Celgene Corp
Publication of HK1054502A1 publication Critical patent/HK1054502A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/7056Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing five-membered rings with nitrogen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716Glucans
    • A61K31/724Cyclodextrins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK03106199A 2000-05-15 2003-08-29 Compositions for the treatment of cancer comprising a topoisomerase inhibitor and thalidomide HK1054502A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20414300P 2000-05-15 2000-05-15
PCT/US2001/015327 WO2001087307A2 (fr) 2000-05-15 2001-05-10 Compositions et methodes de traitement du cancer

Publications (1)

Publication Number Publication Date
HK1054502A1 true HK1054502A1 (en) 2003-12-05

Family

ID=22756804

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03106199A HK1054502A1 (en) 2000-05-15 2003-08-29 Compositions for the treatment of cancer comprising a topoisomerase inhibitor and thalidomide

Country Status (19)

Country Link
US (2) US7435726B2 (fr)
EP (1) EP1307197B1 (fr)
JP (1) JP5409981B2 (fr)
KR (1) KR100790589B1 (fr)
AR (1) AR029084A1 (fr)
AT (1) ATE322266T1 (fr)
AU (2) AU6147401A (fr)
BR (1) BR0110877A (fr)
CA (1) CA2408707C (fr)
DE (1) DE60118571T2 (fr)
DK (1) DK1307197T3 (fr)
ES (1) ES2258084T3 (fr)
HK (1) HK1054502A1 (fr)
MX (1) MXPA02011218A (fr)
NZ (1) NZ522767A (fr)
PT (1) PT1307197E (fr)
TW (1) TWI289449B (fr)
WO (1) WO2001087307A2 (fr)
ZA (1) ZA200209638B (fr)

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Also Published As

Publication number Publication date
EP1307197A2 (fr) 2003-05-07
JP5409981B2 (ja) 2014-02-05
US7435726B2 (en) 2008-10-14
ES2258084T3 (es) 2006-08-16
CA2408707C (fr) 2010-04-13
MXPA02011218A (es) 2004-08-19
WO2001087307A2 (fr) 2001-11-22
DE60118571T2 (de) 2007-02-01
ZA200209638B (en) 2003-11-27
AU2001261474B2 (en) 2006-03-09
BR0110877A (pt) 2003-03-11
TWI289449B (en) 2007-11-11
ATE322266T1 (de) 2006-04-15
AR029084A1 (es) 2003-06-04
KR100790589B1 (ko) 2008-01-02
NZ522767A (en) 2004-07-30
PT1307197E (pt) 2006-08-31
EP1307197B1 (fr) 2006-04-05
US20050148524A1 (en) 2005-07-07
WO2001087307A3 (fr) 2002-07-25
AU6147401A (en) 2001-11-26
KR20030025922A (ko) 2003-03-29
US20020035090A1 (en) 2002-03-21
DE60118571D1 (de) 2006-05-18
JP2003533484A (ja) 2003-11-11
CA2408707A1 (fr) 2001-11-22
DK1307197T3 (da) 2006-07-03

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