HK1051973A1 - Condensation derivatives of thiocolchicine and baccatin and composition thereof. - Google Patents

Condensation derivatives of thiocolchicine and baccatin and composition thereof.

Info

Publication number
HK1051973A1
HK1051973A1 HK03104269A HK03104269A HK1051973A1 HK 1051973 A1 HK1051973 A1 HK 1051973A1 HK 03104269 A HK03104269 A HK 03104269A HK 03104269 A HK03104269 A HK 03104269A HK 1051973 A1 HK1051973 A1 HK 1051973A1
Authority
HK
Hong Kong
Prior art keywords
thiocolchicine
baccatin
composition
condensation derivatives
condensation
Prior art date
Application number
HK03104269A
Other languages
English (en)
Inventor
Ezio Bombardelli
Alessandro Pontiroli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of HK1051973A1 publication Critical patent/HK1051973A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK03104269A 2000-03-17 2003-06-16 Condensation derivatives of thiocolchicine and baccatin and composition thereof. HK1051973A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2000MI000553A IT1319168B1 (it) 2000-03-17 2000-03-17 Derivati di condensazione ad attivita' antitumorale, loro metodo dipreparazione e formulazioni che li contengono.

Publications (1)

Publication Number Publication Date
HK1051973A1 true HK1051973A1 (en) 2003-08-29

Family

ID=11444500

Family Applications (1)

Application Number Title Priority Date Filing Date
HK03104269A HK1051973A1 (en) 2000-03-17 2003-06-16 Condensation derivatives of thiocolchicine and baccatin and composition thereof.

Country Status (21)

Country Link
US (1) US6683109B2 (ja)
EP (1) EP1263431B1 (ja)
JP (1) JP2003526665A (ja)
KR (1) KR100766161B1 (ja)
CN (1) CN1204886C (ja)
AU (2) AU5037701A (ja)
CA (1) CA2403168C (ja)
CZ (1) CZ301626B6 (ja)
DK (1) DK1263431T3 (ja)
ES (1) ES2305067T3 (ja)
HK (1) HK1051973A1 (ja)
HU (1) HU229257B1 (ja)
IL (1) IL151714A0 (ja)
IT (1) IT1319168B1 (ja)
NO (1) NO329422B1 (ja)
PL (1) PL357376A1 (ja)
PT (1) PT1263431E (ja)
RU (1) RU2264393C2 (ja)
SI (1) SI1263431T1 (ja)
SK (1) SK286849B6 (ja)
WO (1) WO2001068089A1 (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR030188A1 (es) 2000-02-02 2003-08-13 Univ Florida State Res Found Compuestos de taxano sustituidos con esteres en el c7; composiciones farmaceuticas que los contienen y proceso para tratar un sujeto mamifero que sufre de una condicion que responde a los taxanos
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
CA2354471A1 (en) * 2001-07-31 2003-01-31 Florida State University Research Foundation, Inc. C10 ester substituted taxanes
US6825236B2 (en) * 2003-04-14 2004-11-30 California Pacific Medical Center Colchicine derivatives
HN2005000054A (es) 2004-02-13 2009-02-18 Florida State University Foundation Inc Taxanos sustituidos con esteres de ciclopentilo en c10
WO2005087222A1 (en) 2004-03-05 2005-09-22 Florida State University Research Foundation, Inc. C7 lactyloxy-substituted taxanes
JP2011517455A (ja) 2008-03-31 2011-06-09 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ（１０）エチルエステルおよびｃ（１０）シクロプロピルエステル置換タキサン

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
AU2400692A (en) * 1991-07-19 1993-02-23 Hybritech Incorporated Trifunctional compounds having specificity for multi-drug resistant cells
WO1993011120A1 (en) * 1991-11-27 1993-06-10 Zynaxis Technologies, Incorporated Compounds, compositions and methods for binding bio-affecting substances to surface membranes of bio-particles
US5426224A (en) * 1993-03-18 1995-06-20 The University Of North Carolina At Chapel Hill Mammalian DNA topoisomerase II inhibitor and method
WO1997024459A1 (en) * 1995-12-29 1997-07-10 Phanos Technologoes, Inc. Method for reducing unwanted cellular adhesions
NZ332475A (en) * 1996-05-08 2000-05-26 Upjohn Co silylated baccatin derivatives, 3-(substituted amino)-3-phenyl-(2R,3S)-isoserinate derivatives, the oxazolidine ester thereof and other immediates used to prepare baccatin derivatives

Also Published As

Publication number Publication date
IT1319168B1 (it) 2003-09-26
CN1416342A (zh) 2003-05-07
EP1263431A1 (en) 2002-12-11
SK286849B6 (sk) 2009-06-05
CN1204886C (zh) 2005-06-08
KR100766161B1 (ko) 2007-10-10
DK1263431T3 (da) 2008-09-29
HUP0300198A2 (hu) 2003-06-28
NO20024353D0 (no) 2002-09-12
AU5037701A (en) 2001-09-24
NO329422B1 (no) 2010-10-18
CA2403168A1 (en) 2001-09-20
EP1263431B1 (en) 2008-05-28
PT1263431E (pt) 2008-08-04
AU2001250377B2 (en) 2004-09-16
KR20020081432A (ko) 2002-10-26
ES2305067T3 (es) 2008-11-01
SI1263431T1 (sl) 2008-08-31
JP2003526665A (ja) 2003-09-09
WO2001068089A1 (en) 2001-09-20
CA2403168C (en) 2010-06-15
SK13112002A3 (sk) 2003-02-04
PL357376A1 (en) 2004-07-26
ITMI20000553A0 (it) 2000-03-17
NO20024353L (no) 2002-09-12
HU229257B1 (en) 2013-10-28
HUP0300198A3 (en) 2005-02-28
CZ301626B6 (cs) 2010-05-05
RU2264393C2 (ru) 2005-11-20
IL151714A0 (en) 2003-04-10
ITMI20000553A1 (it) 2001-09-17
RU2002124523A (ru) 2004-01-10
US20030073734A1 (en) 2003-04-17
US6683109B2 (en) 2004-01-27

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20150312