NO20024353D0 - Kondensasjonsderivater av tiocolchicin og baccatin som antitumormidler - Google Patents

Kondensasjonsderivater av tiocolchicin og baccatin som antitumormidler

Info

Publication number
NO20024353D0
NO20024353D0 NO20024353A NO20024353A NO20024353D0 NO 20024353 D0 NO20024353 D0 NO 20024353D0 NO 20024353 A NO20024353 A NO 20024353A NO 20024353 A NO20024353 A NO 20024353A NO 20024353 D0 NO20024353 D0 NO 20024353D0
Authority
NO
Norway
Prior art keywords
thiocolchicine
baccatin
antitumor agents
condensation derivatives
condensation
Prior art date
Application number
NO20024353A
Other languages
English (en)
Other versions
NO20024353L (no
NO329422B1 (no
Inventor
Ezio Bombardelli
Alessandro Pontiroli
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Publication of NO20024353L publication Critical patent/NO20024353L/no
Publication of NO20024353D0 publication Critical patent/NO20024353D0/no
Publication of NO329422B1 publication Critical patent/NO329422B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D305/00Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO20024353A 2000-03-17 2002-09-12 Kondensasjonsderivater av tiocolchicin og baccatin som antitumormidler, farmasoytiske sammensetninger inneholdende dem og anvendelse derav NO329422B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000MI000553A IT1319168B1 (it) 2000-03-17 2000-03-17 Derivati di condensazione ad attivita' antitumorale, loro metodo dipreparazione e formulazioni che li contengono.
PCT/EP2001/002740 WO2001068089A1 (en) 2000-03-17 2001-03-12 Condensation derivatives of thiocolchicine and baccatin as antitumor agents

Publications (3)

Publication Number Publication Date
NO20024353L NO20024353L (no) 2002-09-12
NO20024353D0 true NO20024353D0 (no) 2002-09-12
NO329422B1 NO329422B1 (no) 2010-10-18

Family

ID=11444500

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20024353A NO329422B1 (no) 2000-03-17 2002-09-12 Kondensasjonsderivater av tiocolchicin og baccatin som antitumormidler, farmasoytiske sammensetninger inneholdende dem og anvendelse derav

Country Status (21)

Country Link
US (1) US6683109B2 (no)
EP (1) EP1263431B1 (no)
JP (1) JP2003526665A (no)
KR (1) KR100766161B1 (no)
CN (1) CN1204886C (no)
AU (2) AU5037701A (no)
CA (1) CA2403168C (no)
CZ (1) CZ301626B6 (no)
DK (1) DK1263431T3 (no)
ES (1) ES2305067T3 (no)
HK (1) HK1051973A1 (no)
HU (1) HU229257B1 (no)
IL (1) IL151714A0 (no)
IT (1) IT1319168B1 (no)
NO (1) NO329422B1 (no)
PL (1) PL357376A1 (no)
PT (1) PT1263431E (no)
RU (1) RU2264393C2 (no)
SI (1) SI1263431T1 (no)
SK (1) SK286849B6 (no)
WO (1) WO2001068089A1 (no)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
CO5280224A1 (es) 2000-02-02 2003-05-30 Univ Florida State Res Found Taxanos sustituidos con ester en c7, utiles como agentes antitumorales y composiciones farmaceuticas que los contienen
CA2354471A1 (en) * 2001-07-31 2003-01-31 Florida State University Research Foundation, Inc. C10 ester substituted taxanes
US6825236B2 (en) * 2003-04-14 2004-11-30 California Pacific Medical Center Colchicine derivatives
HN2005000054A (es) 2004-02-13 2009-02-18 Florida State University Foundation Inc Taxanos sustituidos con esteres de ciclopentilo en c10
EP1737444A4 (en) 2004-03-05 2008-05-21 Univ Florida State Res Found C7-LACTYLOXA-SUBSTITUTED TAXANE
EP2276755A4 (en) 2008-03-31 2011-05-04 Univ Florida State Res Found C (10) -ETHYESTER- AND C (10) -CYCLOPROPYLESTER-SUBSTITUTED TAXANES

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2678930B1 (fr) * 1991-07-10 1995-01-13 Rhone Poulenc Rorer Sa Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
EP0596011A1 (en) * 1991-07-19 1994-05-11 Hybritech Incorporated Trifunctional compounds having specificity for multi-drug resistant cells
JP3682974B2 (ja) * 1991-11-27 2005-08-17 株式会社ファノスディベロップメント バイオ作用性物質をバイオ粒子表面膜へ結合するための化合物、組成、および方法
US5426224A (en) * 1993-03-18 1995-06-20 The University Of North Carolina At Chapel Hill Mammalian DNA topoisomerase II inhibitor and method
WO1997024459A1 (en) * 1995-12-29 1997-07-10 Phanos Technologoes, Inc. Method for reducing unwanted cellular adhesions
CN1216039A (zh) * 1996-05-08 1999-05-05 法玛西雅厄普约翰美国公司 制备紫杉酚的方法

Also Published As

Publication number Publication date
RU2264393C2 (ru) 2005-11-20
IT1319168B1 (it) 2003-09-26
CA2403168C (en) 2010-06-15
ITMI20000553A0 (it) 2000-03-17
PL357376A1 (en) 2004-07-26
CN1416342A (zh) 2003-05-07
EP1263431A1 (en) 2002-12-11
US6683109B2 (en) 2004-01-27
AU5037701A (en) 2001-09-24
NO20024353L (no) 2002-09-12
JP2003526665A (ja) 2003-09-09
DK1263431T3 (da) 2008-09-29
AU2001250377B2 (en) 2004-09-16
HUP0300198A3 (en) 2005-02-28
EP1263431B1 (en) 2008-05-28
SI1263431T1 (sl) 2008-08-31
RU2002124523A (ru) 2004-01-10
KR20020081432A (ko) 2002-10-26
CN1204886C (zh) 2005-06-08
ES2305067T3 (es) 2008-11-01
NO329422B1 (no) 2010-10-18
HU229257B1 (en) 2013-10-28
IL151714A0 (en) 2003-04-10
SK13112002A3 (sk) 2003-02-04
SK286849B6 (sk) 2009-06-05
ITMI20000553A1 (it) 2001-09-17
CZ301626B6 (cs) 2010-05-05
WO2001068089A1 (en) 2001-09-20
KR100766161B1 (ko) 2007-10-10
PT1263431E (pt) 2008-08-04
HUP0300198A2 (hu) 2003-06-28
US20030073734A1 (en) 2003-04-17
CA2403168A1 (en) 2001-09-20
HK1051973A1 (en) 2003-08-29

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