HK1046690B - 核糖取代的新芳族酰胺、其制备方法及其作为药剂的用途 - Google Patents

核糖取代的新芳族酰胺、其制备方法及其作为药剂的用途 Download PDF

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Publication number
HK1046690B
HK1046690B HK02108190.9A HK02108190A HK1046690B HK 1046690 B HK1046690 B HK 1046690B HK 02108190 A HK02108190 A HK 02108190A HK 1046690 B HK1046690 B HK 1046690B
Authority
HK
Hong Kong
Prior art keywords
methyl
formula
compound
hydroxy
oxy
Prior art date
Application number
HK02108190.9A
Other languages
English (en)
Chinese (zh)
Other versions
HK1046690A1 (en
Inventor
Demassey Jacques
Klich Michel
Musicki Branislav
Original Assignee
Novexel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novexel filed Critical Novexel
Publication of HK1046690A1 publication Critical patent/HK1046690A1/xx
Publication of HK1046690B publication Critical patent/HK1046690B/zh

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/075—Benzo[b]pyran-2-ones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HK02108190.9A 1999-04-19 2000-04-18 核糖取代的新芳族酰胺、其制备方法及其作为药剂的用途 HK1046690B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9904866A FR2792320B1 (fr) 1999-04-19 1999-04-19 Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
FR99/04866 1999-04-19
PCT/FR2000/000999 WO2000063222A2 (fr) 1999-04-19 2000-04-18 Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
HK1046690A1 HK1046690A1 (en) 2003-01-24
HK1046690B true HK1046690B (zh) 2006-03-10

Family

ID=9544554

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02108190.9A HK1046690B (zh) 1999-04-19 2000-04-18 核糖取代的新芳族酰胺、其制备方法及其作为药剂的用途

Country Status (24)

Country Link
US (1) US6579902B1 (enExample)
EP (1) EP1173455A2 (enExample)
JP (1) JP2002542253A (enExample)
KR (1) KR100693258B1 (enExample)
CN (1) CN1213055C (enExample)
AP (1) AP2001002312A0 (enExample)
AU (1) AU769514B2 (enExample)
CA (1) CA2363945A1 (enExample)
CZ (1) CZ20013708A3 (enExample)
EA (1) EA004304B1 (enExample)
FR (1) FR2792320B1 (enExample)
HK (1) HK1046690B (enExample)
HU (1) HUP0200778A3 (enExample)
ID (1) ID30562A (enExample)
IL (1) IL146018A0 (enExample)
NO (1) NO320703B1 (enExample)
NZ (1) NZ515108A (enExample)
PL (1) PL354192A1 (enExample)
SK (1) SK14842001A3 (enExample)
TR (1) TR200103009T2 (enExample)
UA (1) UA72919C2 (enExample)
WO (1) WO2000063222A2 (enExample)
YU (1) YU80301A (enExample)
ZA (1) ZA200108627B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2844273B1 (fr) * 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
KR100649357B1 (ko) * 2004-05-04 2006-11-24 제일약품주식회사 항염증 활성을 갖는 크로멘-2-온 모핵 히드록사민 산유도체, 이의 제조방법 및 이를 포함하는 염증 질환의치료를 위한 조성물
US8212011B2 (en) * 2004-11-03 2012-07-03 University Of Kansas Novobiocin analogues
US9120774B2 (en) 2004-11-03 2015-09-01 University Of Kansas Novobiocin analogues having modified sugar moieties
US7608594B2 (en) * 2004-11-03 2009-10-27 University Of Kansas Novobiocin analogues as anticancer agents
US7622451B2 (en) * 2004-11-03 2009-11-24 University Of Kansas Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
US8212012B2 (en) * 2004-11-03 2012-07-03 University Of Kansas Novobiocin analogues having modified sugar moieties
US7960353B2 (en) * 2007-05-10 2011-06-14 University Of Kansas Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
WO2010014617A1 (en) * 2008-07-28 2010-02-04 University Of Kansas Heat shock protein 90 inhibitor dosing methods
US20110082098A1 (en) * 2009-09-30 2011-04-07 University Of Kansas Novobiocin analogues and treatment of polycystic kidney disease
US11827664B2 (en) 2018-05-14 2023-11-28 Reata Pharmaceuticals, Inc Biaryl amides with modified sugar groups for treatment of diseases associated with heat shock protein pathway

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652536A (en) * 1969-06-02 1972-03-28 Upjohn Co Novenamine compounds and derivatives
US3890297A (en) * 1973-03-29 1975-06-17 Upjohn Co Process for n-acylating novenamine

Also Published As

Publication number Publication date
EA004304B1 (ru) 2004-02-26
EA200101100A1 (ru) 2002-04-25
AP2001002312A0 (en) 2001-12-31
FR2792320B1 (fr) 2003-05-09
WO2000063222A3 (fr) 2001-05-31
NO20015058L (no) 2001-12-17
YU80301A (sh) 2005-07-19
FR2792320A1 (fr) 2000-10-20
HUP0200778A3 (en) 2003-03-28
IL146018A0 (en) 2002-07-25
AU769514B2 (en) 2004-01-29
PL354192A1 (en) 2003-12-29
ZA200108627B (en) 2002-10-21
KR20020008155A (ko) 2002-01-29
CA2363945A1 (fr) 2000-10-26
TR200103009T2 (tr) 2002-05-21
HK1046690A1 (en) 2003-01-24
UA72919C2 (uk) 2005-05-16
NZ515108A (en) 2004-01-30
ID30562A (id) 2001-12-20
WO2000063222A2 (fr) 2000-10-26
EP1173455A2 (fr) 2002-01-23
CZ20013708A3 (cs) 2002-04-17
CN1357001A (zh) 2002-07-03
KR100693258B1 (ko) 2007-03-13
US6579902B1 (en) 2003-06-17
JP2002542253A (ja) 2002-12-10
HUP0200778A2 (hu) 2002-07-29
SK14842001A3 (sk) 2003-05-02
NO320703B1 (no) 2006-01-16
AU4125600A (en) 2000-11-02
CN1213055C (zh) 2005-08-03
NO20015058D0 (no) 2001-10-18

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Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090418