FR2792320B1 - Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments - Google Patents

Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments

Info

Publication number
FR2792320B1
FR2792320B1 FR9904866A FR9904866A FR2792320B1 FR 2792320 B1 FR2792320 B1 FR 2792320B1 FR 9904866 A FR9904866 A FR 9904866A FR 9904866 A FR9904866 A FR 9904866A FR 2792320 B1 FR2792320 B1 FR 2792320B1
Authority
FR
France
Prior art keywords
ribosis
medicaments
application
preparation process
aromatic amides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9904866A
Other languages
English (en)
French (fr)
Other versions
FR2792320A1 (fr
Inventor
Jacques Demassey
Michel Klich
Branislav Musicki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Marion Roussel
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR9904866A priority Critical patent/FR2792320B1/fr
Application filed by Hoechst Marion Roussel, Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel
Priority to TR2001/03009T priority patent/TR200103009T2/xx
Priority to NZ515108A priority patent/NZ515108A/xx
Priority to CA002363945A priority patent/CA2363945A1/fr
Priority to CNB008091900A priority patent/CN1213055C/zh
Priority to HU0200778A priority patent/HUP0200778A3/hu
Priority to PL00354192A priority patent/PL354192A1/xx
Priority to US09/980,728 priority patent/US6579902B1/en
Priority to AU41256/00A priority patent/AU769514B2/en
Priority to JP2000612312A priority patent/JP2002542253A/ja
Priority to IDW00200102505A priority patent/ID30562A/id
Priority to KR1020017013340A priority patent/KR100693258B1/ko
Priority to YU80301A priority patent/YU80301A/sh
Priority to CZ20013708A priority patent/CZ20013708A3/cs
Priority to HK02108190.9A priority patent/HK1046690B/zh
Priority to EA200101100A priority patent/EA004304B1/ru
Priority to PCT/FR2000/000999 priority patent/WO2000063222A2/fr
Priority to EP00920823A priority patent/EP1173455A2/fr
Priority to IL14601800A priority patent/IL146018A0/xx
Priority to SK1484-2001A priority patent/SK14842001A3/sk
Priority to APAP/P/2001/002312A priority patent/AP2001002312A0/en
Priority to UA2001117895A priority patent/UA72919C2/uk
Publication of FR2792320A1 publication Critical patent/FR2792320A1/fr
Priority to NO20015058A priority patent/NO320703B1/no
Priority to ZA200108627A priority patent/ZA200108627B/en
Application granted granted Critical
Publication of FR2792320B1 publication Critical patent/FR2792320B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/075—Benzo[b]pyran-2-ones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FR9904866A 1999-04-19 1999-04-19 Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments Expired - Fee Related FR2792320B1 (fr)

Priority Applications (24)

Application Number Priority Date Filing Date Title
FR9904866A FR2792320B1 (fr) 1999-04-19 1999-04-19 Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
CZ20013708A CZ20013708A3 (cs) 1999-04-19 2000-04-18 Nové aromatické amidy substituované ribózou, způsob jejich přípravy a jejich léčebná aplikace
CA002363945A CA2363945A1 (fr) 1999-04-19 2000-04-18 Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
CNB008091900A CN1213055C (zh) 1999-04-19 2000-04-18 核糖取代的新芳族酰胺、其制备方法及其作为药剂的用途
EA200101100A EA004304B1 (ru) 1999-04-19 2000-04-18 Новые ароматические амиды, замещенные рибозой, способ их получения и их применение в качестве лекарств
PL00354192A PL354192A1 (en) 1999-04-19 2000-04-18 Novel ribose-substituted aromatic amides, method for the production and use thereof as medicaments
US09/980,728 US6579902B1 (en) 1999-04-19 2000-04-18 Ribose-substituted aromatic amides, method for the production and use thereof as medicaments
AU41256/00A AU769514B2 (en) 1999-04-19 2000-04-18 Novel ribose-substituted aromatic amides, method for the production and use thereof as medicaments
JP2000612312A JP2002542253A (ja) 1999-04-19 2000-04-18 新規のリボース置換芳香族アミド、それらの製造方法及びそれらの薬剤としての使用
IDW00200102505A ID30562A (id) 1999-04-19 2000-04-18 Senyawa-senyawa amina aromatik tersubstitusi ribosa baru, metode pembuatannya dan penggunaannya sebagai obat
KR1020017013340A KR100693258B1 (ko) 1999-04-19 2000-04-18 리보스로 치환된 신규 방향족 아미드, 그 제조 방법 및의약 용도
YU80301A YU80301A (sh) 1999-04-19 2000-04-18 Novi aromatični amidi supstituisani ribozom, postupak za njihovo pripremanje i njihova primena kao medikamenata
TR2001/03009T TR200103009T2 (tr) 1999-04-19 2000-04-18 Yeni aromatik amidlerin hazırlanma yöntemleri ve ilaç olarak kullanımları
HK02108190.9A HK1046690B (zh) 1999-04-19 2000-04-18 核糖取代的新芳族酰胺、其制备方法及其作为药剂的用途
HU0200778A HUP0200778A3 (en) 1999-04-19 2000-04-18 Novel ribose-substituted aromatic amides, method for the production and use thereof as medicaments and their intermediates
PCT/FR2000/000999 WO2000063222A2 (fr) 1999-04-19 2000-04-18 Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
EP00920823A EP1173455A2 (fr) 1999-04-19 2000-04-18 Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments
IL14601800A IL146018A0 (en) 1999-04-19 2000-04-18 New aromatic amides substituted by a ribose, their preparation process and their use as medicaments
SK1484-2001A SK14842001A3 (sk) 1999-04-19 2000-04-18 Aromatické amidy substituované ribózou, spôsob a medziprodukty na ich výrobu, ich použitie a farmaceutické kompozície na ich báze
NZ515108A NZ515108A (en) 1999-04-19 2000-04-18 Novel ribose-substituted aromatic amides, method for the production and use thereof as medicaments
UA2001117895A UA72919C2 (uk) 1999-04-19 2000-04-18 Ароматичні аміди, заміщені рибозою, спосіб їх одержання та фармацевтична композиція
APAP/P/2001/002312A AP2001002312A0 (en) 1999-04-19 2000-04-18 New aromatic amides sustituted by a ribose, their preparation process and their use as medicaments.
NO20015058A NO320703B1 (no) 1999-04-19 2001-10-18 Nye ribose-substituerte aromatiske amider, fremgangsmate for deres fremstilling og farmasoytisk preparat inneholdende disse.
ZA200108627A ZA200108627B (en) 1999-04-19 2001-10-19 Novel ribose-substituted aromatic amides, method for the production and use thereof as medicaments.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9904866A FR2792320B1 (fr) 1999-04-19 1999-04-19 Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
FR2792320A1 FR2792320A1 (fr) 2000-10-20
FR2792320B1 true FR2792320B1 (fr) 2003-05-09

Family

ID=9544554

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9904866A Expired - Fee Related FR2792320B1 (fr) 1999-04-19 1999-04-19 Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments

Country Status (24)

Country Link
US (1) US6579902B1 (enExample)
EP (1) EP1173455A2 (enExample)
JP (1) JP2002542253A (enExample)
KR (1) KR100693258B1 (enExample)
CN (1) CN1213055C (enExample)
AP (1) AP2001002312A0 (enExample)
AU (1) AU769514B2 (enExample)
CA (1) CA2363945A1 (enExample)
CZ (1) CZ20013708A3 (enExample)
EA (1) EA004304B1 (enExample)
FR (1) FR2792320B1 (enExample)
HK (1) HK1046690B (enExample)
HU (1) HUP0200778A3 (enExample)
ID (1) ID30562A (enExample)
IL (1) IL146018A0 (enExample)
NO (1) NO320703B1 (enExample)
NZ (1) NZ515108A (enExample)
PL (1) PL354192A1 (enExample)
SK (1) SK14842001A3 (enExample)
TR (1) TR200103009T2 (enExample)
UA (1) UA72919C2 (enExample)
WO (1) WO2000063222A2 (enExample)
YU (1) YU80301A (enExample)
ZA (1) ZA200108627B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2844273B1 (fr) * 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
KR100649357B1 (ko) * 2004-05-04 2006-11-24 제일약품주식회사 항염증 활성을 갖는 크로멘-2-온 모핵 히드록사민 산유도체, 이의 제조방법 및 이를 포함하는 염증 질환의치료를 위한 조성물
US8212011B2 (en) * 2004-11-03 2012-07-03 University Of Kansas Novobiocin analogues
US9120774B2 (en) 2004-11-03 2015-09-01 University Of Kansas Novobiocin analogues having modified sugar moieties
US7608594B2 (en) * 2004-11-03 2009-10-27 University Of Kansas Novobiocin analogues as anticancer agents
US7622451B2 (en) * 2004-11-03 2009-11-24 University Of Kansas Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
US8212012B2 (en) * 2004-11-03 2012-07-03 University Of Kansas Novobiocin analogues having modified sugar moieties
US7960353B2 (en) * 2007-05-10 2011-06-14 University Of Kansas Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
WO2010014617A1 (en) * 2008-07-28 2010-02-04 University Of Kansas Heat shock protein 90 inhibitor dosing methods
US20110082098A1 (en) * 2009-09-30 2011-04-07 University Of Kansas Novobiocin analogues and treatment of polycystic kidney disease
US11827664B2 (en) 2018-05-14 2023-11-28 Reata Pharmaceuticals, Inc Biaryl amides with modified sugar groups for treatment of diseases associated with heat shock protein pathway

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652536A (en) * 1969-06-02 1972-03-28 Upjohn Co Novenamine compounds and derivatives
US3890297A (en) * 1973-03-29 1975-06-17 Upjohn Co Process for n-acylating novenamine

Also Published As

Publication number Publication date
EA004304B1 (ru) 2004-02-26
EA200101100A1 (ru) 2002-04-25
AP2001002312A0 (en) 2001-12-31
WO2000063222A3 (fr) 2001-05-31
NO20015058L (no) 2001-12-17
YU80301A (sh) 2005-07-19
FR2792320A1 (fr) 2000-10-20
HUP0200778A3 (en) 2003-03-28
IL146018A0 (en) 2002-07-25
AU769514B2 (en) 2004-01-29
PL354192A1 (en) 2003-12-29
ZA200108627B (en) 2002-10-21
KR20020008155A (ko) 2002-01-29
CA2363945A1 (fr) 2000-10-26
TR200103009T2 (tr) 2002-05-21
HK1046690A1 (en) 2003-01-24
UA72919C2 (uk) 2005-05-16
NZ515108A (en) 2004-01-30
ID30562A (id) 2001-12-20
WO2000063222A2 (fr) 2000-10-26
EP1173455A2 (fr) 2002-01-23
CZ20013708A3 (cs) 2002-04-17
CN1357001A (zh) 2002-07-03
KR100693258B1 (ko) 2007-03-13
US6579902B1 (en) 2003-06-17
JP2002542253A (ja) 2002-12-10
HUP0200778A2 (hu) 2002-07-29
SK14842001A3 (sk) 2003-05-02
NO320703B1 (no) 2006-01-16
AU4125600A (en) 2000-11-02
CN1213055C (zh) 2005-08-03
HK1046690B (zh) 2006-03-10
NO20015058D0 (no) 2001-10-18

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TP Transmission of property
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Effective date: 20091231