CN1213055C - 核糖取代的新芳族酰胺、其制备方法及其作为药剂的用途 - Google Patents

核糖取代的新芳族酰胺、其制备方法及其作为药剂的用途 Download PDF

Info

Publication number
CN1213055C
CN1213055C CNB008091900A CN00809190A CN1213055C CN 1213055 C CN1213055 C CN 1213055C CN B008091900 A CNB008091900 A CN B008091900A CN 00809190 A CN00809190 A CN 00809190A CN 1213055 C CN1213055 C CN 1213055C
Authority
CN
China
Prior art keywords
methyl
formula
compound
oxy
product
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CNB008091900A
Other languages
English (en)
Chinese (zh)
Other versions
CN1357001A (zh
Inventor
J·德马西
M·克利赫
B·穆斯基
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of CN1357001A publication Critical patent/CN1357001A/zh
Application granted granted Critical
Publication of CN1213055C publication Critical patent/CN1213055C/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/06—Benzopyran radicals
    • C07H17/065—Benzo[b]pyrans
    • C07H17/075—Benzo[b]pyran-2-ones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
CNB008091900A 1999-04-19 2000-04-18 核糖取代的新芳族酰胺、其制备方法及其作为药剂的用途 Expired - Fee Related CN1213055C (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR99/04866 1999-04-19
FR9904866A FR2792320B1 (fr) 1999-04-19 1999-04-19 Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments

Publications (2)

Publication Number Publication Date
CN1357001A CN1357001A (zh) 2002-07-03
CN1213055C true CN1213055C (zh) 2005-08-03

Family

ID=9544554

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB008091900A Expired - Fee Related CN1213055C (zh) 1999-04-19 2000-04-18 核糖取代的新芳族酰胺、其制备方法及其作为药剂的用途

Country Status (24)

Country Link
US (1) US6579902B1 (enExample)
EP (1) EP1173455A2 (enExample)
JP (1) JP2002542253A (enExample)
KR (1) KR100693258B1 (enExample)
CN (1) CN1213055C (enExample)
AP (1) AP2001002312A0 (enExample)
AU (1) AU769514B2 (enExample)
CA (1) CA2363945A1 (enExample)
CZ (1) CZ20013708A3 (enExample)
EA (1) EA004304B1 (enExample)
FR (1) FR2792320B1 (enExample)
HK (1) HK1046690B (enExample)
HU (1) HUP0200778A3 (enExample)
ID (1) ID30562A (enExample)
IL (1) IL146018A0 (enExample)
NO (1) NO320703B1 (enExample)
NZ (1) NZ515108A (enExample)
PL (1) PL354192A1 (enExample)
SK (1) SK14842001A3 (enExample)
TR (1) TR200103009T2 (enExample)
UA (1) UA72919C2 (enExample)
WO (1) WO2000063222A2 (enExample)
YU (1) YU80301A (enExample)
ZA (1) ZA200108627B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2844273B1 (fr) * 2002-09-05 2008-04-04 Aventis Pharma Sa Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens.
US7439253B2 (en) * 2002-12-06 2008-10-21 Novexel Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors
KR100649357B1 (ko) * 2004-05-04 2006-11-24 제일약품주식회사 항염증 활성을 갖는 크로멘-2-온 모핵 히드록사민 산유도체, 이의 제조방법 및 이를 포함하는 염증 질환의치료를 위한 조성물
US8212012B2 (en) * 2004-11-03 2012-07-03 University Of Kansas Novobiocin analogues having modified sugar moieties
US8212011B2 (en) * 2004-11-03 2012-07-03 University Of Kansas Novobiocin analogues
US7622451B2 (en) * 2004-11-03 2009-11-24 University Of Kansas Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
AU2005301957B2 (en) * 2004-11-03 2012-02-23 Department Of Health And Human Services Novobiocin analogues as anticancer agents
US9120774B2 (en) 2004-11-03 2015-09-01 University Of Kansas Novobiocin analogues having modified sugar moieties
US7960353B2 (en) * 2007-05-10 2011-06-14 University Of Kansas Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders
US20100022635A1 (en) * 2008-07-28 2010-01-28 University Of Kansas Heat shock protein 90 inhibitor dosing methods
US20110082098A1 (en) * 2009-09-30 2011-04-07 University Of Kansas Novobiocin analogues and treatment of polycystic kidney disease
EP3794009A1 (en) 2018-05-14 2021-03-24 Reata Pharmaceuticals, Inc. Biaryl amides with modified sugar groups for treatment of diseases associated with heat shock protein pathway

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3652536A (en) * 1969-06-02 1972-03-28 Upjohn Co Novenamine compounds and derivatives
US3890297A (en) * 1973-03-29 1975-06-17 Upjohn Co Process for n-acylating novenamine

Also Published As

Publication number Publication date
PL354192A1 (en) 2003-12-29
KR20020008155A (ko) 2002-01-29
TR200103009T2 (tr) 2002-05-21
HUP0200778A3 (en) 2003-03-28
CN1357001A (zh) 2002-07-03
IL146018A0 (en) 2002-07-25
AU769514B2 (en) 2004-01-29
SK14842001A3 (sk) 2003-05-02
NO20015058L (no) 2001-12-17
AU4125600A (en) 2000-11-02
JP2002542253A (ja) 2002-12-10
HK1046690A1 (en) 2003-01-24
NO320703B1 (no) 2006-01-16
EA004304B1 (ru) 2004-02-26
HUP0200778A2 (hu) 2002-07-29
ZA200108627B (en) 2002-10-21
YU80301A (sh) 2005-07-19
WO2000063222A3 (fr) 2001-05-31
EA200101100A1 (ru) 2002-04-25
UA72919C2 (uk) 2005-05-16
HK1046690B (zh) 2006-03-10
ID30562A (id) 2001-12-20
NO20015058D0 (no) 2001-10-18
US6579902B1 (en) 2003-06-17
KR100693258B1 (ko) 2007-03-13
EP1173455A2 (fr) 2002-01-23
CZ20013708A3 (cs) 2002-04-17
NZ515108A (en) 2004-01-30
FR2792320B1 (fr) 2003-05-09
CA2363945A1 (fr) 2000-10-26
WO2000063222A2 (fr) 2000-10-26
AP2001002312A0 (en) 2001-12-31
FR2792320A1 (fr) 2000-10-20

Similar Documents

Publication Publication Date Title
CN1052984C (zh) 新的红霉素衍生物、其制备方法及其作为药物的应用
CN1059445C (zh) 红霉素的新型衍生物,其制备方法及作为药物的应用
CN1213055C (zh) 核糖取代的新芳族酰胺、其制备方法及其作为药剂的用途
CN1151165C (zh) 具有抗炎活性的大环内酯
CN1269833C (zh) 新的芳香酰胺、其制备方法以及作为药物的应用
CN1090581A (zh) 红霉素的新衍生物和它们的制备方法及其作为药物的应用
CN1192216A (zh) 用于治疗和预防内毒素血症的取代的脂多糖
CN1659178A (zh) 6、11二环红霉素衍生物
CN1384838A (zh) 大环内酯抗感染药物
CN1259135A (zh) 9－肟红霉素衍生物
CN1259955A (zh) C－4"－取代的大环内酯衍生物
CN1269836C (zh) 用于改进抗炎治疗的细胞靶向的免疫细胞特异性大环内酯化合物与抗炎化合物的共轭物
CN86104479A (zh) 吡啶酮羧酸衍生物的制备方法
CN1240707C (zh) 2－卤代－6－0－取代的酮内酯衍生物
CN1250544C (zh) 吡啶并芳基苯基噁唑烷酮抗菌剂和相关组合物及方法
CN1117965A (zh) 取代的4-苯基-吡啶酮和4-苯基-2-烷氧基吡啶
CN1215403A (zh) 头孢烯化合物及含该化合物的医药
CN1037773C (zh) 含杂原子的三环化合物
CN1024197C (zh) 表鬼臼毒吡喃葡糖甙的酰化衍生物的制备方法
CN1633444A (zh) 6－11双环酮大环内酯衍生物
CN1346362A (zh) 除虫菌素衍生物
CN1780846A (zh) 双官能杂环化合物及其制备和使用方法
CN1025199C (zh) 3-脱氧碳霉糖基太乐内酯衍生物的制备方法
CN1202173A (zh) 表鬼臼毒素2″,3″二脱氧糖苷的新型胺衍生物,其制备方法其作为药物的应用及其抗癌治疗的应用
CN1031192C (zh) 3′-脱氨基-4′-脱氧-4′-氨基-8-氟蒽环苷类的制备方法

Legal Events

Date Code Title Description
C06 Publication
C10 Entry into substantive examination
PB01 Publication
SE01 Entry into force of request for substantive examination
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
ASS Succession or assignment of patent right

Owner name: SMIRNOVSURF CO., LTD.

Free format text: FORMER OWNER: VENTIS PHARMA S.A.

Effective date: 20080104

C41 Transfer of patent application or patent right or utility model
TR01 Transfer of patent right

Effective date of registration: 20080104

Address after: French Roman

Patentee after: Aventis Pharma S.A.

Address before: French Anthony

Patentee before: AVENTIS PHARMA S.A.

C17 Cessation of patent right
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20050803