YU80301A - Novi aromatični amidi supstituisani ribozom, postupak za njihovo pripremanje i njihova primena kao medikamenata - Google Patents
Novi aromatični amidi supstituisani ribozom, postupak za njihovo pripremanje i njihova primena kao medikamenataInfo
- Publication number
- YU80301A YU80301A YU80301A YUP80301A YU80301A YU 80301 A YU80301 A YU 80301A YU 80301 A YU80301 A YU 80301A YU P80301 A YUP80301 A YU P80301A YU 80301 A YU80301 A YU 80301A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- alkyl
- hydrogen
- medicaments
- production
- substituted aromatic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/06—Benzopyran radicals
- C07H17/065—Benzo[b]pyrans
- C07H17/075—Benzo[b]pyran-2-ones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Virology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Abstract
Jedinjenja formule (I) kod kojih R1 je alkil, alkenil ili alkinil, O-alkil, O-alkenil, ili eventualno supstituisan, eventualno prekinut O-alkinilom, R2 je vodonik ili halogen, R3 je vodonik, alkil ili halogen, R4 je NHR' li NHOR", R' ili R" su isti ili različiti i predstavljaju vodonik, alkil, alkenil ili alkinil, aril, R5 je vodonik ili O-alkil, R8 je alkil ili CH2-O-alkil, R7 je vodonik ili alkil, ili R6 i R7 obrazuju jedan prsten zajedno sa ugljenikovim atomom na koji su vezani, kao i njihove adicione soli baza. Jedinjenja formule (I) imaju antibiotička svojstva.[Compounds of formula (I); wherein R1 = alkyl, alkenyl or alkynyl, O-alkyl, O-alkenyl or optionally substituted, optionally interrupted O- alkynyl; R2 = hydrogen or halogen; R3 = hydrogen, alkyl or halogen; R4= NHR' or NHOR", R' or R" are identical or different and represent hydrogen, alkyl, alkenyl or alkynyl, aryl; R5= hydrogen or O-alkyl; R6= alkyl or CH2-O-alkyl; R7= hydrogen or alkyl or R6 et R7 form a cycle together with the carbon carrying them in addition to the addition salts thereof with bases. The compounds of formula (I) have antibiotic properties.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9904866A FR2792320B1 (fr) | 1999-04-19 | 1999-04-19 | Nouveaux amides aromatiques substitues par un ribose, leur procede de preparation et leur application comme medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU80301A true YU80301A (sh) | 2005-07-19 |
Family
ID=9544554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU80301A YU80301A (sh) | 1999-04-19 | 2000-04-18 | Novi aromatični amidi supstituisani ribozom, postupak za njihovo pripremanje i njihova primena kao medikamenata |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US6579902B1 (sh) |
| EP (1) | EP1173455A2 (sh) |
| JP (1) | JP2002542253A (sh) |
| KR (1) | KR100693258B1 (sh) |
| CN (1) | CN1213055C (sh) |
| AP (1) | AP2001002312A0 (sh) |
| AU (1) | AU769514B2 (sh) |
| CA (1) | CA2363945A1 (sh) |
| CZ (1) | CZ20013708A3 (sh) |
| EA (1) | EA004304B1 (sh) |
| FR (1) | FR2792320B1 (sh) |
| HK (1) | HK1046690B (sh) |
| HU (1) | HUP0200778A3 (sh) |
| ID (1) | ID30562A (sh) |
| IL (1) | IL146018A0 (sh) |
| NO (1) | NO320703B1 (sh) |
| NZ (1) | NZ515108A (sh) |
| PL (1) | PL354192A1 (sh) |
| SK (1) | SK14842001A3 (sh) |
| TR (1) | TR200103009T2 (sh) |
| UA (1) | UA72919C2 (sh) |
| WO (1) | WO2000063222A2 (sh) |
| YU (1) | YU80301A (sh) |
| ZA (1) | ZA200108627B (sh) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2844273B1 (fr) * | 2002-09-05 | 2008-04-04 | Aventis Pharma Sa | Nouveaux composes heterocycliques, procede et intermediaires de preparation et utilisation comme medicament, notamment comme inhibiteurs de beta-lactamases et anti-bacteriens. |
| US7439253B2 (en) * | 2002-12-06 | 2008-10-21 | Novexel | Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors |
| KR100649357B1 (ko) * | 2004-05-04 | 2006-11-24 | 제일약품주식회사 | 항염증 활성을 갖는 크로멘-2-온 모핵 히드록사민 산유도체, 이의 제조방법 및 이를 포함하는 염증 질환의치료를 위한 조성물 |
| US9120774B2 (en) | 2004-11-03 | 2015-09-01 | University Of Kansas | Novobiocin analogues having modified sugar moieties |
| US8212012B2 (en) * | 2004-11-03 | 2012-07-03 | University Of Kansas | Novobiocin analogues having modified sugar moieties |
| US7622451B2 (en) * | 2004-11-03 | 2009-11-24 | University Of Kansas | Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders |
| CA2585091C (en) * | 2004-11-03 | 2016-07-19 | University Of Kansas | Novobiocin analogues as anticancer agents |
| US8212011B2 (en) * | 2004-11-03 | 2012-07-03 | University Of Kansas | Novobiocin analogues |
| US7960353B2 (en) * | 2007-05-10 | 2011-06-14 | University Of Kansas | Novobiocin analogues as neuroprotective agents and in the treatment of autoimmune disorders |
| US20100022635A1 (en) * | 2008-07-28 | 2010-01-28 | University Of Kansas | Heat shock protein 90 inhibitor dosing methods |
| WO2011041593A1 (en) * | 2009-09-30 | 2011-04-07 | University Of Kansas | Novobiocin analogues and treatment of polycystic kidney disease |
| WO2019222269A1 (en) | 2018-05-14 | 2019-11-21 | Reata Pharmaceuticals, Inc. | Biaryl amides with modified sugar groups for treatment of diseases associated with heat shock protein pathway |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3652536A (en) * | 1969-06-02 | 1972-03-28 | Upjohn Co | Novenamine compounds and derivatives |
| US3890297A (en) * | 1973-03-29 | 1975-06-17 | Upjohn Co | Process for n-acylating novenamine |
-
1999
- 1999-04-19 FR FR9904866A patent/FR2792320B1/fr not_active Expired - Fee Related
-
2000
- 2000-04-18 AU AU41256/00A patent/AU769514B2/en not_active Ceased
- 2000-04-18 JP JP2000612312A patent/JP2002542253A/ja active Pending
- 2000-04-18 PL PL00354192A patent/PL354192A1/xx not_active Application Discontinuation
- 2000-04-18 CA CA002363945A patent/CA2363945A1/fr not_active Abandoned
- 2000-04-18 AP APAP/P/2001/002312A patent/AP2001002312A0/en unknown
- 2000-04-18 US US09/980,728 patent/US6579902B1/en not_active Expired - Fee Related
- 2000-04-18 EA EA200101100A patent/EA004304B1/ru not_active IP Right Cessation
- 2000-04-18 HU HU0200778A patent/HUP0200778A3/hu unknown
- 2000-04-18 ID IDW00200102505A patent/ID30562A/id unknown
- 2000-04-18 UA UA2001117895A patent/UA72919C2/uk unknown
- 2000-04-18 IL IL14601800A patent/IL146018A0/xx unknown
- 2000-04-18 TR TR2001/03009T patent/TR200103009T2/xx unknown
- 2000-04-18 YU YU80301A patent/YU80301A/sh unknown
- 2000-04-18 SK SK1484-2001A patent/SK14842001A3/sk unknown
- 2000-04-18 CZ CZ20013708A patent/CZ20013708A3/cs unknown
- 2000-04-18 EP EP00920823A patent/EP1173455A2/fr not_active Withdrawn
- 2000-04-18 WO PCT/FR2000/000999 patent/WO2000063222A2/fr active Application Filing
- 2000-04-18 NZ NZ515108A patent/NZ515108A/xx unknown
- 2000-04-18 CN CNB008091900A patent/CN1213055C/zh not_active Expired - Fee Related
- 2000-04-18 KR KR1020017013340A patent/KR100693258B1/ko not_active IP Right Cessation
-
2001
- 2001-10-18 NO NO20015058A patent/NO320703B1/no unknown
- 2001-10-19 ZA ZA200108627A patent/ZA200108627B/en unknown
-
2002
- 2002-11-12 HK HK02108190.9A patent/HK1046690B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EA200101100A1 (ru) | 2002-04-25 |
| AP2001002312A0 (en) | 2001-12-31 |
| ID30562A (id) | 2001-12-20 |
| NO20015058D0 (no) | 2001-10-18 |
| KR20020008155A (ko) | 2002-01-29 |
| CZ20013708A3 (cs) | 2002-04-17 |
| NO20015058L (no) | 2001-12-17 |
| US6579902B1 (en) | 2003-06-17 |
| CN1357001A (zh) | 2002-07-03 |
| AU769514B2 (en) | 2004-01-29 |
| CN1213055C (zh) | 2005-08-03 |
| FR2792320B1 (fr) | 2003-05-09 |
| NZ515108A (en) | 2004-01-30 |
| CA2363945A1 (fr) | 2000-10-26 |
| WO2000063222A3 (fr) | 2001-05-31 |
| IL146018A0 (en) | 2002-07-25 |
| HUP0200778A2 (hu) | 2002-07-29 |
| EA004304B1 (ru) | 2004-02-26 |
| PL354192A1 (en) | 2003-12-29 |
| AU4125600A (en) | 2000-11-02 |
| HK1046690A1 (en) | 2003-01-24 |
| TR200103009T2 (tr) | 2002-05-21 |
| SK14842001A3 (sk) | 2003-05-02 |
| EP1173455A2 (fr) | 2002-01-23 |
| ZA200108627B (en) | 2002-10-21 |
| KR100693258B1 (ko) | 2007-03-13 |
| NO320703B1 (no) | 2006-01-16 |
| UA72919C2 (uk) | 2005-05-16 |
| WO2000063222A2 (fr) | 2000-10-26 |
| HK1046690B (zh) | 2006-03-10 |
| FR2792320A1 (fr) | 2000-10-20 |
| JP2002542253A (ja) | 2002-12-10 |
| HUP0200778A3 (en) | 2003-03-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MY126951A (en) | Beta2-adrenoceptor agonists | |
| YU80301A (sh) | Novi aromatični amidi supstituisani ribozom, postupak za njihovo pripremanje i njihova primena kao medikamenata | |
| ES2187473T3 (es) | Triarylimidazoles. | |
| HUP0302943A2 (hu) | Új heterociklusos vegyületek, előállításuk és alkalmazásuk gyógyszerekként, különösen antibakteriális szerekként | |
| HUP0301387A2 (hu) | Szintetikus módszerek aplidin és új tumorellenes származékok előállítására | |
| NO994452D0 (no) | Substituerte 4-arylmetylen-2-imino-2,3-dihydrotiazoler og derivater, og deres farmasöytiske anvendelse | |
| MY127144A (en) | New anticholinergics which may be used as medicaments as well as processes for preparing them | |
| MY114672A (en) | New erythromycin derivatives,processes for preparing them,the products thus prepared,pharmaceutical compositions containing them,and their use as medicaments | |
| BG106073A (en) | Quinoline derivatives as inhibitors of mek enzymes | |
| HUP0202799A2 (hu) | Herbicid hatású izoxazolinszármazékok és azt tartalmazó készítmény | |
| GB0018272D0 (en) | Chemical compounds IV | |
| TW200716528A (en) | Cyclopropanecarboxamide derivatives | |
| PE20010544A1 (es) | Derivados de mutilina utiles como agentes antibacterianos | |
| NZ527249A (en) | Purine derivatives as purinergic receptor antagonists | |
| BG106343A (en) | Carboxylic acid amides, medicaments containing these compounds and the use and production thereof | |
| MXPA05007296A (es) | Compuestos de (2-carboxamido)(3-amino)tiofeno. | |
| IL158343A (en) | Dopamine glycoconjugate compounds, pharmaceutical compositions comprising them, processes for their preparation and use thereof in the manufacture of medicaments and as medicaments for treating parkinson's disease | |
| HK1093351A1 (en) | Disperse azo dyestuffs | |
| WO2003082861A3 (en) | Morpholinyl-urea derivatives for use of the treatment of inflammatory diseases | |
| ES482700A1 (es) | Procedimiento para la obtencion de alfa-azolil-beta-hidroxi-cetonas. | |
| MXPA03011682A (es) | Derivados sustituidos de n-acil -anilina, su preparacion y su uso como medicamento. | |
| MXPA04005940A (es) | Acidos 3-(imidazolil)-2-aminopropanoicos. | |
| MXPA01013148A (es) | Nuevos derivados de amonio cuaternario, metodo para la preparacion de los mismos y uso farmaceutico. | |
| HUP0500203A2 (hu) | Acil-3-karboxi-fenil-karbamid-származékok, eljárás ezek előállítására és ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk | |
| NO941516L (no) | 3-kinolylsubstituerte dihydropyridiner, fremgangsmåter for deres fremstilling og deres anvendelse |