HK1041610A1 - 改進的頭孢菌素的體內生產方法 - Google Patents

改進的頭孢菌素的體內生產方法

Info

Publication number
HK1041610A1
HK1041610A1 HK02103286.5A HK02103286A HK1041610A1 HK 1041610 A1 HK1041610 A1 HK 1041610A1 HK 02103286 A HK02103286 A HK 02103286A HK 1041610 A1 HK1041610 A1 HK 1041610A1
Authority
HK
Hong Kong
Prior art keywords
cephalosporins
improved
vivo production
vivo
production
Prior art date
Application number
HK02103286.5A
Other languages
English (en)
Chinese (zh)
Inventor
R‧A‧L‧博文博格
R‧科克曼
E‧科漢
Original Assignee
Dsm公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm公司 filed Critical Dsm公司
Publication of HK1041610A1 publication Critical patent/HK1041610A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
HK02103286.5A 1998-12-22 2002-05-02 改進的頭孢菌素的體內生產方法 HK1041610A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98204469 1998-12-22
PCT/EP1999/010292 WO2000037671A2 (en) 1998-12-22 1999-12-21 Improved in vivo production of cephalosporins

Publications (1)

Publication Number Publication Date
HK1041610A1 true HK1041610A1 (zh) 2002-07-12

Family

ID=8234568

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02103286.5A HK1041610A1 (zh) 1998-12-22 2002-05-02 改進的頭孢菌素的體內生產方法

Country Status (7)

Country Link
EP (1) EP1141372A2 (ja)
JP (1) JP2002533092A (ja)
KR (1) KR20010089672A (ja)
CN (1) CN1331751A (ja)
AU (1) AU3042600A (ja)
HK (1) HK1041610A1 (ja)
WO (1) WO2000037671A2 (ja)

Families Citing this family (70)

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CA2704654C (en) 2007-11-20 2015-02-10 Dsm Ip Assets B.V. Succinic acid production in a eukaryotic cell
ES2389989T3 (es) 2007-11-20 2012-11-05 Dsm Ip Assets B.V. Producción de ácido dicarboxílico en levadura recombinante
US20110318795A1 (en) 2007-11-20 2011-12-29 Verwaal Rene Dicarboxylic acid production in a filamentous fungus
CN101555463B (zh) * 2008-04-08 2012-05-30 中国科学院上海生命科学研究院湖州工业生物技术中心 表达头孢菌素脱乙酰酶的重组大肠杆菌菌株及其构建方法
EP2116136A1 (en) 2008-05-08 2009-11-11 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Novel phytases
US8735100B2 (en) 2009-03-17 2014-05-27 Nederlandse Organisatie Voor Toegepast -Natuurwetenschappelijk Onderzoek Tno Cellulose and ligno-cellulose active proteins
WO2010118932A1 (en) 2009-04-15 2010-10-21 Dsm Ip Assets B.V. Dicarboxylic acid production process
UA108853C2 (uk) 2009-07-10 2015-06-25 Спосіб ферментації галактози
MX2012012171A (es) 2010-04-21 2013-02-27 Dsm Ip Assets Bv Proceso para la produccion de celulas que tienen la capacidad de convertir arabinosa.
EP2388331A1 (en) 2010-05-21 2011-11-23 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Constitutive promoter
CN103189505A (zh) 2010-10-13 2013-07-03 帝斯曼知识产权资产管理有限公司 具有通透酶活性的多肽
WO2012143513A2 (en) 2011-04-22 2012-10-26 Dsm Ip Assets B.V. Yeast cell capable of converting sugars including arabinose and xylose
AR087423A1 (es) 2011-08-04 2014-03-19 Dsm Ip Assets Bv Celula capaz de fermentar azucares pentosas
EP2554668A1 (en) 2011-08-04 2013-02-06 DSM IP Assets B.V. A pentose sugar fermenting cell
CN104203005A (zh) 2012-01-23 2014-12-10 帝斯曼知识产权资产管理有限公司 二萜的生产
BR112015008370B1 (pt) 2012-10-16 2022-10-18 Dsm Ip Assets B.V Células de saccharomyces com conversão de pentose melhorada e processo para a produção de um produto da fermentação
EP2772545A1 (en) 2013-03-01 2014-09-03 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Starch active proteins
EP2981610A1 (en) 2013-04-05 2016-02-10 Université du Luxembourg Biotechnological production of itaconic acid
WO2014178717A1 (en) 2013-05-02 2014-11-06 Nederlandse Organisatie Voor Toegepast-Natuurwetenschappelijk Onderzoek Tno Novel organic acid pathway
EP3004366B1 (en) 2013-05-31 2019-02-27 DSM IP Assets B.V. Microorganisms for diterpene production
EP3885443A1 (en) 2013-07-15 2021-09-29 DSM IP Assets B.V. Diterpene production
CN108064226A (zh) 2013-07-31 2018-05-22 帝斯曼知识产权资产管理有限公司 甜菊糖苷的回收
CN107429273A (zh) 2015-02-16 2017-12-01 帝斯曼知识产权资产管理有限公司 用于在厌氧条件下生产衣康酸的方法
EP3862426A3 (en) 2015-03-16 2021-11-17 DSM IP Assets B.V. Udp-glycosyltransferases
EP3274448B1 (en) 2015-03-23 2021-08-11 DSM IP Assets B.V. Udp-glycosyltransferases from solanum lycopersicum
EP3718417A1 (en) 2015-04-03 2020-10-07 DSM IP Assets B.V. Steviol glycosides
WO2016170045A1 (en) 2015-04-21 2016-10-27 Dsm Ip Assets B.V. Geranylgeranyl pyrophosphate synthase
ES2755680T3 (es) 2015-05-22 2020-04-23 Dsm Ip Assets Bv Célula de levadura que consume acetato
MY192153A (en) 2015-07-10 2022-08-02 Dsm Ip Assets Bv Steviol glycoside composition
WO2017025649A1 (en) 2015-08-13 2017-02-16 Dsm Ip Assets B.V. Steviol glycoside transport
WO2017050652A1 (en) 2015-09-25 2017-03-30 Dsm Ip Assets B.V. Asparaginase
BR112018006724A2 (pt) 2015-10-05 2018-10-09 Dsm Ip Assets Bv ácido caurenoico hidroxilases
MY186400A (en) 2015-10-06 2021-07-22 Dsm Ip Assets Bv Eukaryotic cell with increased production of fermentation product
CN116064263A (zh) 2015-12-30 2023-05-05 帝斯曼知识产权资产管理有限公司 三酰基甘油的部分酶水解
KR20180097745A (ko) 2015-12-30 2018-08-31 디에스엠 아이피 어셋츠 비.브이. 트라이아실글리세롤의 부분 효소적 가수 분해
EP3435771A1 (en) 2016-03-31 2019-02-06 DSM IP Assets B.V. Enzyme composition and preparation of a dairy product with improved properties
EP3435770A1 (en) 2016-03-31 2019-02-06 DSM IP Assets B.V. Production of milk with low lactose content
WO2017167849A1 (en) 2016-03-31 2017-10-05 Dsm Ip Assets B.V. Enzyme composition and preparation of a dairy product with improved properties
WO2017216136A1 (en) 2016-06-14 2017-12-21 Dsm Ip Assets B.V. Recombinant yeast cell
CN116286420A (zh) 2016-07-13 2023-06-23 帝斯曼知识产权资产管理有限公司 苹果酸脱氢酶
EP3497109A1 (en) 2016-08-09 2019-06-19 DSM IP Assets B.V. Crystallization of steviol glycosides
CA3033243A1 (en) 2016-08-09 2018-02-15 Dsm Ip Assets B.V. Crystallization of steviol glycosides
CN110036114B (zh) 2016-08-26 2023-09-29 勒萨弗尔公司 提高的衣康酸生产
KR101808192B1 (ko) * 2016-08-26 2018-01-18 아미코젠주식회사 7-아미노세팔로스포란산의 고농도 생산 재조합 아크레모니움 크리소제눔 균주의 제조방법 및 이 방법으로 제조된 균주
WO2018073107A1 (en) 2016-10-19 2018-04-26 Dsm Ip Assets B.V. Eukaryotic cell comprising xylose isomerase
US11225647B2 (en) 2016-10-27 2022-01-18 Dsm Ip Assets B.V. Geranylgeranyl pyrophosphate synthases
BR112019011525A2 (pt) 2016-12-08 2020-01-28 Dsm Ip Assets Bv ácido caurenoico hidroxilases
WO2018114912A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
WO2018114938A1 (en) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Lipolytic enzyme variants
US10889807B2 (en) 2016-12-21 2021-01-12 Dsm Ip Assets B.V. Lipolytic enzyme variants
EP3559222A1 (en) 2016-12-21 2019-10-30 DSM IP Assets B.V. Lipolytic enzyme variants
WO2018114995A1 (en) 2016-12-22 2018-06-28 Dsm Ip Assets B.V. Fermentation process for producing steviol glycosides
CA3064143A1 (en) 2017-06-13 2018-12-20 Dsm Ip Assets B.V. Recombinant yeast cell
EP4155400A1 (en) 2017-06-27 2023-03-29 DSM IP Assets B.V. Udp-glycosyltransferases
CN111133111A (zh) 2017-09-26 2020-05-08 帝斯曼知识产权资产管理有限公司 消耗乙酸的菌株
EP3533878A1 (en) 2018-02-28 2019-09-04 Dutch DNA Biotech B.V. Process for producing citramalic acid employing aspergillus
BR112020025589A2 (pt) 2018-06-19 2021-03-23 Dsm Ip Assets B.V. variantes de enzima lipolítica
AU2021367159A1 (en) 2020-10-22 2023-05-04 Cargill, Incorporated Microorganisms for diterpene production
AU2022297881A1 (en) 2021-06-24 2024-01-18 Fonterra Co-Operative Group Limited Recombinant beta-lactoglobulin
EP4370691A1 (en) 2021-07-12 2024-05-22 Danisco US Inc. Recombinant yeast cell
WO2023285294A1 (en) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Recombinant yeast cell
EP4370688A1 (en) 2021-07-12 2024-05-22 Danisco Us Inc Recombinant yeast cell
CN118056011A (zh) 2021-07-12 2024-05-17 丹尼斯科美国公司 重组酵母细胞
WO2023285280A1 (en) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Recombinant yeast cell
WO2023079049A1 (en) 2021-11-04 2023-05-11 Dsm Ip Assets B.V. Variant polypeptide and recombinant yeast cell
WO2023079048A1 (en) 2021-11-04 2023-05-11 Dsm Ip Assets B.V. Process for the production of ethanol and recombinant yeast cell
WO2023079050A1 (en) 2021-11-04 2023-05-11 Dsm Ip Assets B.V. Recombinant yeast cell
AU2022388727A1 (en) 2021-11-09 2024-05-16 Amgen Inc. Production of therapeutic proteins
WO2023222614A1 (en) 2022-05-16 2023-11-23 Dsm Ip Assets B.V. Lipolytic enzyme variants

Family Cites Families (5)

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Publication number Priority date Publication date Assignee Title
KR100227711B1 (ko) * 1991-10-15 1999-12-01 한스 발터 라벤 7-아미노세팔로스포란산 및 7-아미노데아세틸세팔로스포란산 제조를 위한 신규한 생물학적 공정
EP0566897A3 (en) * 1992-04-07 1994-07-06 Hoechst Ag The complete gene (cefg) encoding the acetyl-coa: deacetylcephalosporin c acetyltransferase of cephalosporium acremonium, its isolation and use
SK282617B6 (sk) * 1993-07-30 2002-10-08 Dsm N. V. Spôsob výroby a izolácie 7-aminodesacetoxycefalosporánovej kyseliny
PL180799B1 (pl) * 1993-07-30 2001-04-30 Gist Brocades Bv Sposób wydajnego wytwarzania 7-ADCA poprzez 2-(karboksyetylotio)acetylo-7-ADCA i 3-(karboksymetylotio)-propionylo-7-ADCA
ATE231919T1 (de) * 1997-04-22 2003-02-15 Dsm Nv Verfahren für die fermentative produktion von deazylierten cephalosporinen.

Also Published As

Publication number Publication date
WO2000037671A2 (en) 2000-06-29
AU3042600A (en) 2000-07-12
KR20010089672A (ko) 2001-10-08
JP2002533092A (ja) 2002-10-08
WO2000037671A3 (en) 2000-09-14
EP1141372A2 (en) 2001-10-10
CN1331751A (zh) 2002-01-16

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