ZA976295B - Process for the production of adipoyl cephalosporins - Google Patents

Process for the production of adipoyl cephalosporins

Info

Publication number
ZA976295B
ZA976295B ZA976295A ZA976295A ZA976295B ZA 976295 B ZA976295 B ZA 976295B ZA 976295 A ZA976295 A ZA 976295A ZA 976295 A ZA976295 A ZA 976295A ZA 976295 B ZA976295 B ZA 976295B
Authority
ZA
South Africa
Prior art keywords
adipoyl
cephalosporins
production
adipoyl cephalosporins
Prior art date
Application number
ZA976295A
Inventor
Roelof Ary Lans Bovenberg
Jan Metske Van Der Laan
Richard Kerkman
Maarten Nieboer
Original Assignee
Gist Brocades Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades Bv filed Critical Gist Brocades Bv
Publication of ZA976295B publication Critical patent/ZA976295B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA976295A 1996-07-16 1997-07-16 Process for the production of adipoyl cephalosporins ZA976295B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP96201988 1996-07-16

Publications (1)

Publication Number Publication Date
ZA976295B true ZA976295B (en) 1998-09-01

Family

ID=8224186

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA976295A ZA976295B (en) 1996-07-16 1997-07-16 Process for the production of adipoyl cephalosporins

Country Status (3)

Country Link
AU (1) AU4114697A (en)
WO (1) WO1998002551A2 (en)
ZA (1) ZA976295B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6320069B1 (en) 1996-07-02 2001-11-20 Toray Industries, Inc. Production of optically active ketone
JP2000512860A (en) * 1997-04-22 2000-10-03 ギスト ブロカデス ベスローテン フェンノートシャップ How to prepare β-lactam antibiotics
ZA983396B (en) * 1997-04-22 1998-10-27 Gist Brocades Bv A method for controlling the solubility of a beta-lactam nucleus
ID27054A (en) 1998-05-19 2001-02-22 Dsm Nv IMPROVING THE PRODUCTION OF SEPALOSPORIN IN LIVING ORGANISMS
US6699699B2 (en) * 2002-03-26 2004-03-02 Synmax Biochemical Co., Ltd. Mutated penicillin expandases
WO2005103261A1 (en) * 2004-04-22 2005-11-03 Orchid Chemicals & Pharmaceuticals Ltd. Modified expandase enzyme and its use
BRPI0515976A (en) * 2004-10-13 2008-08-12 Dsm Ip Assets Bv mutant expandases
CN107304418B (en) * 2016-04-18 2022-08-26 百瑞全球有限公司 Penicillin expandase mutant, DNA encoding the mutant, kit containing the mutant and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5070020A (en) * 1988-05-09 1991-12-03 Eli Lilly And Company Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase
US5082772A (en) * 1988-10-24 1992-01-21 Eli Lilly And Company Process for preparing deacetylcephalosporin c
WO1997020053A2 (en) * 1995-11-27 1997-06-05 Gist-Brocades B.V. Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin g

Also Published As

Publication number Publication date
WO1998002551A2 (en) 1998-01-22
WO1998002551A3 (en) 1998-02-19
AU4114697A (en) 1998-02-09

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