HK1041610A1 - 改進的頭孢菌素的體內生產方法 - Google Patents

改進的頭孢菌素的體內生產方法

Info

Publication number
HK1041610A1
HK1041610A1 HK02103286.5A HK02103286A HK1041610A1 HK 1041610 A1 HK1041610 A1 HK 1041610A1 HK 02103286 A HK02103286 A HK 02103286A HK 1041610 A1 HK1041610 A1 HK 1041610A1
Authority
HK
Hong Kong
Prior art keywords
cephalosporins
improved
vivo production
vivo
production
Prior art date
Application number
HK02103286.5A
Other languages
English (en)
Chinese (zh)
Inventor
R‧A‧L‧博文博格
R‧科克曼
E‧科漢
Original Assignee
Dsm公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dsm公司 filed Critical Dsm公司
Publication of HK1041610A1 publication Critical patent/HK1041610A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
HK02103286.5A 1998-12-22 2002-05-02 改進的頭孢菌素的體內生產方法 HK1041610A1 (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98204469 1998-12-22
PCT/EP1999/010292 WO2000037671A2 (fr) 1998-12-22 1999-12-21 Production in vivo amelioree de cephalosporines

Publications (1)

Publication Number Publication Date
HK1041610A1 true HK1041610A1 (zh) 2002-07-12

Family

ID=8234568

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02103286.5A HK1041610A1 (zh) 1998-12-22 2002-05-02 改進的頭孢菌素的體內生產方法

Country Status (7)

Country Link
EP (1) EP1141372A2 (fr)
JP (1) JP2002533092A (fr)
KR (1) KR20010089672A (fr)
CN (1) CN1331751A (fr)
AU (1) AU3042600A (fr)
HK (1) HK1041610A1 (fr)
WO (1) WO2000037671A2 (fr)

Families Citing this family (70)

* Cited by examiner, † Cited by third party
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WO2004113508A1 (fr) * 2003-06-20 2004-12-29 Dsm Ip Assets B.V. Production d'intermediaires de la cephalosporine dans penicillium chrysogenum
ES2383473T3 (es) 2007-11-20 2012-06-21 Dsm Ip Assets B.V. Producción de ácido dicarboxílico en eucariotas
US20110318795A1 (en) 2007-11-20 2011-12-29 Verwaal Rene Dicarboxylic acid production in a filamentous fungus
CN101896606B (zh) 2007-11-20 2016-12-21 帝斯曼知识产权资产管理有限公司 在重组酵母中生产二羧酸
CN101555463B (zh) * 2008-04-08 2012-05-30 中国科学院上海生命科学研究院湖州工业生物技术中心 表达头孢菌素脱乙酰酶的重组大肠杆菌菌株及其构建方法
EP2116136A1 (fr) 2008-05-08 2009-11-11 Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNO Nouvelles phytases
EP2408907B8 (fr) 2009-03-17 2018-04-18 Dutch DNA Biotech B.V. Utilisation des protéines actives sur cellulose et lignocellulose
EP2419518A1 (fr) 2009-04-15 2012-02-22 DSM IP Assets B.V. Procédé de production d'acide dicarboxylique
UA108853C2 (uk) 2009-07-10 2015-06-25 Спосіб ферментації галактози
JP2013524797A (ja) 2010-04-21 2013-06-20 ディーエスエム アイピー アセッツ ビー．ブイ． アラビノースを転化できる細胞を製造する方法
EP2388331A1 (fr) 2010-05-21 2011-11-23 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Promoteur constitutif
US9034608B2 (en) 2010-10-13 2015-05-19 Dsm Ip Assets, B.V. Polypeptides with permease activity
WO2012143513A2 (fr) 2011-04-22 2012-10-26 Dsm Ip Assets B.V. Cellule de levure pouvant convertir des sucres comprenant l'arabinose et le xylose
EP2554668A1 (fr) 2011-08-04 2013-02-06 DSM IP Assets B.V. Cellule de fermentation de sucre de pentose
AR087423A1 (es) 2011-08-04 2014-03-19 Dsm Ip Assets Bv Celula capaz de fermentar azucares pentosas
AU2013211605B2 (en) 2012-01-23 2017-04-06 Dsm Ip Assets B.V. Diterpene production
AR093025A1 (es) 2012-10-16 2015-05-13 Dsm Ip Assets Bv Celulas con conversion mejorada de pentosas
EP2772545A1 (fr) 2013-03-01 2014-09-03 Nederlandse Organisatie voor toegepast -natuurwetenschappelijk onderzoek TNO Protéines d'amidon actives
US20160060660A1 (en) 2013-04-05 2016-03-03 Université Du Luxembourg Biotechnological production of itaconic acid
CN105431539B (zh) 2013-05-02 2021-05-25 乐斯福公司 新的有机酸通路
DK3004366T3 (da) 2013-05-31 2019-05-20 Dsm Ip Assets Bv Mikroorganismer til diterpenproduktion
BR112016000745B1 (pt) 2013-07-15 2021-01-05 Dsm Ip Assets B.V. processo para a preparação de rebaudiosídeo m
EP3536697A1 (fr) 2013-07-31 2019-09-11 DSM IP Assets B.V. Récupération de glycosides de stéviol
US10443077B2 (en) 2015-02-16 2019-10-15 Dsm Ip Assets B.V. Fermentation process for producing itaconic acid under nitrogen free conditions
US10604743B2 (en) 2015-03-16 2020-03-31 Dsm Ip Assets B.V. UDP-glycosyltransferases
WO2016151046A1 (fr) 2015-03-23 2016-09-29 Dsm Ip Assets B.V. Udp-glycosyltransférases de solanum lycopersicum
US11344051B2 (en) 2015-04-03 2022-05-31 Dsm Ip Assets B.V. Steviol glycosides
CA2980649A1 (fr) 2015-04-21 2016-10-27 Dsm Ip Assets B.V. Geranylgeranyle pyrophosphate synthase
HUE045909T2 (hu) 2015-05-22 2020-01-28 Dsm Ip Assets Bv Acetátot fogyasztó élesztõsejt
WO2017009294A1 (fr) 2015-07-10 2017-01-19 Dsm Ip Assets B.V. Composition de glycoside de stéviol
CA2993744A1 (fr) 2015-08-13 2017-02-16 Dsm Ip Assets B.V. Transport de glycoside de steviol
WO2017050652A1 (fr) 2015-09-25 2017-03-30 Dsm Ip Assets B.V. Asparaginase
EP4043558A3 (fr) 2015-10-05 2022-11-16 DSM IP Assets B.V. Hydroxylases de l'acide kaurénoïque
ES2767728T3 (es) 2015-10-06 2020-06-18 Dsm Ip Assets Bv Célula eucariota con elevada producción de producto de fermentación
EP3397771A2 (fr) 2015-12-30 2018-11-07 DSM IP Assets B.V. Hydrolyse enzymatique partielle des triacylglycérols
WO2017115323A2 (fr) 2015-12-30 2017-07-06 Dsm Ip Assets B.V. Hydrolyse enzymatique partielle des triacylglycérols
WO2017167848A1 (fr) 2016-03-31 2017-10-05 Dsm Ip Assets B.V. Composition enzymatique et préparation d'un produit laitier ayant des propriétés améliorées
WO2017167849A1 (fr) 2016-03-31 2017-10-05 Dsm Ip Assets B.V. Composition enzymatique et préparation d'un produit laitier aux propriétés améliorées
EP3435770A1 (fr) 2016-03-31 2019-02-06 DSM IP Assets B.V. Production de lait à faible teneur en lactose
WO2017216136A1 (fr) 2016-06-14 2017-12-21 Dsm Ip Assets B.V. Cellule de levure recombinée
US10787649B2 (en) 2016-07-13 2020-09-29 Dsm Ip Assets B.V. Malate dehyrogenases
WO2018029272A1 (fr) 2016-08-09 2018-02-15 Dsm Ip Assets B.V. Cristallisation de glycosides de stéviol
CA3033243A1 (fr) 2016-08-09 2018-02-15 Dsm Ip Assets B.V. Cristallisation de glycosides de steviol
KR101808192B1 (ko) * 2016-08-26 2018-01-18 아미코젠주식회사 7-아미노세팔로스포란산의 고농도 생산 재조합 아크레모니움 크리소제눔 균주의 제조방법 및 이 방법으로 제조된 균주
WO2018037123A1 (fr) 2016-08-26 2018-03-01 Lesaffre Et Compagnie Production améliorée d'acide itaconique
WO2018073107A1 (fr) 2016-10-19 2018-04-26 Dsm Ip Assets B.V. Cellule eucaryote comprenant de la xylose isomérase
AU2017350309A1 (en) 2016-10-27 2019-05-02 Dsm Ip Assets B.V. Geranylgeranyl pyrophosphate synthases
EP3551751A1 (fr) 2016-12-08 2019-10-16 DSM IP Assets B.V. Hydroxylases d'acide kaurénoïque
WO2018114941A1 (fr) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Variants d'enzyme lipolytique
BR112019012559A2 (pt) 2016-12-21 2019-11-26 Dsm Ip Assets Bv variantes de enzima lipolítica
WO2018114938A1 (fr) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Variants d'enzyme lipolytique
WO2018114912A1 (fr) 2016-12-21 2018-06-28 Dsm Ip Assets B.V. Variants d'enzyme lipolytique
WO2018114995A1 (fr) 2016-12-22 2018-06-28 Dsm Ip Assets B.V. Procédés de fermentation pour la production de glycosides de stéviol
US11667886B2 (en) 2017-06-13 2023-06-06 Dsm Ip Assets B.V. Recombinant yeast cell
EP4155400A1 (fr) 2017-06-27 2023-03-29 DSM IP Assets B.V. Glycosyltransférases udp
CN111133111A (zh) 2017-09-26 2020-05-08 帝斯曼知识产权资产管理有限公司 消耗乙酸的菌株
EP3533878A1 (fr) 2018-02-28 2019-09-04 Dutch DNA Biotech B.V. Procédé de production d'acide 2-hydroxy-2-méthylsuccinique en utilisant d'aspergillus
EP3809852A1 (fr) 2018-06-19 2021-04-28 DSM IP Assets B.V. Variants d'enzyme lipolytique
CA3198626A1 (fr) 2020-10-22 2022-04-28 Dsm Ip Assets B.V. Microorganismes pour la production de diterpenes
EP4359426A2 (fr) 2021-06-24 2024-05-01 Fonterra Co-Operative Group Limited Protéines de recombinaison
WO2023285281A1 (fr) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Cellule de levure recombinée
WO2023285282A1 (fr) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Cellule de levure recombinée
WO2023285280A1 (fr) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Cellule de levure recombinante
WO2023285279A1 (fr) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Cellule de levure recombinée
WO2023285294A1 (fr) 2021-07-12 2023-01-19 Dsm Ip Assets B.V. Cellule de levure recombinée
WO2023079049A1 (fr) 2021-11-04 2023-05-11 Dsm Ip Assets B.V. Polypeptide variant et cellule de levure recombinée
WO2023079048A1 (fr) 2021-11-04 2023-05-11 Dsm Ip Assets B.V. Procédé de production d'éthanol et cellule de levure recombinante
WO2023079050A1 (fr) 2021-11-04 2023-05-11 Dsm Ip Assets B.V. Cellule de levure recombinée
WO2023086793A1 (fr) 2021-11-09 2023-05-19 Amgen Inc. Production de protéines thérapeutiques
WO2023222614A1 (fr) 2022-05-16 2023-11-23 Dsm Ip Assets B.V. Variants d'enzymes lipolytiques

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SK280569B6 (sk) * 1991-10-15 2000-03-13 Gist-Brocades B.V. Biologický spôsob výroby kyseliny7-aminodeacetylce
EP0566897A3 (en) * 1992-04-07 1994-07-06 Hoechst Ag The complete gene (cefg) encoding the acetyl-coa: deacetylcephalosporin c acetyltransferase of cephalosporium acremonium, its isolation and use
SK282624B6 (sk) * 1993-07-30 2002-10-08 Dsm N. V. Spôsob výroby a izolácie 7-aminodesacetoxycefalosporánovej kyseliny
ES2194873T3 (es) * 1993-07-30 2003-12-01 Dsm Ip Assets Bv Procedimiento para la produccion eficaz de 7-adca a traves de 3-(carboxietil)propionil-7-adca.
SI0915988T1 (en) * 1997-04-22 2003-06-30 Dsm N.V. Process for the fermentative production of deacylated cephalosporins

Also Published As

Publication number Publication date
EP1141372A2 (fr) 2001-10-10
AU3042600A (en) 2000-07-12
WO2000037671A2 (fr) 2000-06-29
WO2000037671A3 (fr) 2000-09-14
JP2002533092A (ja) 2002-10-08
KR20010089672A (ko) 2001-10-08
CN1331751A (zh) 2002-01-16

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