HK1038924A1 - 噻吩並嘧啶類 - Google Patents

噻吩並嘧啶類 Download PDF

Info

Publication number
HK1038924A1
HK1038924A1 HK02100600.0A HK02100600A HK1038924A1 HK 1038924 A1 HK1038924 A1 HK 1038924A1 HK 02100600 A HK02100600 A HK 02100600A HK 1038924 A1 HK1038924 A1 HK 1038924A1
Authority
HK
Hong Kong
Prior art keywords
pyrimidin
chloro
benzothieno
acid
formula
Prior art date
Application number
HK02100600.0A
Other languages
English (en)
Chinese (zh)
Inventor
R‧约纳斯
R‧約納斯
F‧-W‧克鲁克森
P‧舍林
F‧-W‧克魯克森
M‧克里斯塔德勒
P‧捨林
M‧克裏斯塔德勒
Original Assignee
默克专利股份公司
默克專利股份公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 默克专利股份公司, 默克專利股份公司 filed Critical 默克专利股份公司
Publication of HK1038924A1 publication Critical patent/HK1038924A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK02100600.0A 1997-11-28 1998-11-19 噻吩並嘧啶類 HK1038924A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19752952A DE19752952A1 (de) 1997-11-28 1997-11-28 Thienopyrimidine
DE19752952.6 1997-11-28
PCT/EP1998/007436 WO1999028325A1 (de) 1997-11-28 1998-11-19 Thienopyrimidine

Publications (1)

Publication Number Publication Date
HK1038924A1 true HK1038924A1 (zh) 2002-04-04

Family

ID=7850200

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02100600.0A HK1038924A1 (zh) 1997-11-28 1998-11-19 噻吩並嘧啶類

Country Status (24)

Country Link
US (2) US6420368B1 (https=)
EP (1) EP1036078B1 (https=)
JP (1) JP4314341B2 (https=)
KR (1) KR20010032445A (https=)
CN (1) CN1138780C (https=)
AR (1) AR010962A1 (https=)
AT (1) ATE361926T1 (https=)
AU (1) AU742433B2 (https=)
BR (1) BR9815409A (https=)
CA (1) CA2311922C (https=)
CO (1) CO4980884A1 (https=)
CZ (1) CZ291068B6 (https=)
DE (2) DE19752952A1 (https=)
ES (1) ES2285796T3 (https=)
HK (1) HK1038924A1 (https=)
HU (1) HUP0100488A3 (https=)
ID (1) ID24571A (https=)
NO (1) NO20002702L (https=)
PL (1) PL341156A1 (https=)
RU (1) RU2217431C2 (https=)
SK (1) SK7772000A3 (https=)
TW (1) TW472059B (https=)
WO (1) WO1999028325A1 (https=)
ZA (1) ZA9810845B (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19819023A1 (de) * 1998-04-29 1999-11-04 Merck Patent Gmbh Thienopyrimidine
EP1167367A4 (en) 1999-03-30 2002-04-24 Nippon Soda Co THIENOPYRIMIDINE COMPOUNDS AND SALTS THEREOF, AND PROCESS FOR THE PREPARATION THEREOF
DE19942474A1 (de) * 1999-09-06 2001-03-15 Merck Patent Gmbh Pyrazolo[4,3-d]pyrimidine
JP2004500425A (ja) 2000-04-19 2004-01-08 リリー　アイコス　リミテッド　ライアビリティ　カンパニー パーキンソン病の処置に対する環状ｇｍｐ特異的ホスホジエステラーゼインヒビターの使用
DE10031584A1 (de) 2000-06-29 2002-01-10 Merck Patent Gmbh 5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
DE10031585A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 2-Aminoalkyl-thieno[2,3-d]pyrimidine
DE10042997A1 (de) * 2000-09-01 2002-03-14 Merck Patent Gmbh Thienopyrimidine
KR20030034232A (ko) * 2000-09-29 2003-05-01 닛뽕소다 가부시키가이샤 티에노피리미딘 화합물 및 그 염 및 제조방법
DE10058663A1 (de) * 2000-11-25 2002-05-29 Merck Patent Gmbh Verwendung von Thienopyrimidinen
US20040072846A1 (en) * 2000-12-19 2004-04-15 Hans-Michael Eggenweiler Pharmaceutical formulation containing thienopyrimidines and antithrombotics, calcium antagonists, prostaglandins or prostaglandin derivatives
DE10064994A1 (de) * 2000-12-23 2002-07-04 Merck Patent Gmbh Sulfamidothienopyrimidine
DE10103647A1 (de) * 2001-01-27 2002-08-01 Merck Patent Gmbh Verfahren zur Herstellung eines Pyrazolo (4,3-d) pyrimidinderivates
CZ20032339A3 (cs) * 2001-01-31 2004-09-15 Merck Patent Gmbh Farmaceutický prostředek obsahující parazolo [4,3-d]pyrimidiny a nitráty nebo thienopyrimidiny a nitráty
US6849638B2 (en) * 2001-04-30 2005-02-01 Bayer Pharmaceuticals Corporation 4-amino-5,6-substituted thiopheno [2,3-d] pyrimidines, pharmaceutical compositions containing the same, and their use in the treatment or prevention of pde7b-mediated diseases and conditions
DE10148883A1 (de) * 2001-10-04 2003-04-10 Merck Patent Gmbh Pyrimidinderivate
WO2003035653A1 (en) * 2001-10-26 2003-05-01 Nippon Soda Co.,Ltd. Pyridothienopyrimidine compound and salt thereof
EA008596B1 (ru) 2003-04-29 2007-06-29 Пфайзер Инк. 5,7-ДИАМИНОПИРАЗОЛО[4,3-d]ПИРИМИДИНЫ, ПОЛЕЗНЫЕ ПРИ ЛЕЧЕНИИ ГИПЕРТЕНЗИИ
US7572799B2 (en) 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
DE602005011784D1 (de) 2004-04-07 2009-01-29 Pfizer Pyrazoloä4,3-düpyrimidine
GB0420719D0 (en) * 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
ES2259892B1 (es) * 2004-11-30 2007-11-01 Laboratorios Almirall S.A. Nuevos derivados de piridotienopirimidina.
ES2259891B1 (es) * 2004-11-30 2007-11-01 Laboratorios Almirall S.A. Nuevos derivados de piridotienopirimidina.
MX2014000648A (es) 2011-07-19 2014-09-25 Infinity Pharmaceuticals Inc Compuestos heterociclicos y sus usos.
CN109297923A (zh) * 2018-09-19 2019-02-01 南通出入境检验检疫局检验检疫综合技术中心 纺织品中微量含氟整理剂的测定方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE245666C (https=)
DD245666A1 (de) * 1985-09-20 1987-05-13 Univ Halle Wittenberg Verfahren zur herstellung von 4-aminosubstituierten thieno 2,3-d-pyrimidin-2-ylessigsaeureestern
GB9311920D0 (en) 1993-06-09 1993-07-28 Pfizer Ltd Therapeutic agents
US5869486A (en) 1995-02-24 1999-02-09 Ono Pharmaceutical Co., Ltd. Fused pyrimidines and pyriazines as pharmaceutical compounds
DE19644228A1 (de) * 1996-10-24 1998-04-30 Merck Patent Gmbh Thienopyrimidine

Also Published As

Publication number Publication date
EP1036078B1 (de) 2007-05-09
HUP0100488A3 (en) 2003-03-28
CZ291068B6 (cs) 2002-12-11
HUP0100488A2 (hu) 2001-09-28
CO4980884A1 (es) 2000-11-27
CN1306534A (zh) 2001-08-01
US6495554B2 (en) 2002-12-17
AR010962A1 (es) 2000-07-12
NO20002702D0 (no) 2000-05-26
US20020132818A1 (en) 2002-09-19
WO1999028325A1 (de) 1999-06-10
CA2311922C (en) 2009-09-29
DE19752952A1 (de) 1999-06-02
KR20010032445A (ko) 2001-04-25
NO20002702L (no) 2000-05-26
BR9815409A (pt) 2000-10-24
ATE361926T1 (de) 2007-06-15
ES2285796T3 (es) 2007-11-16
US6420368B1 (en) 2002-07-16
JP4314341B2 (ja) 2009-08-12
CN1138780C (zh) 2004-02-18
TW472059B (en) 2002-01-11
AU742433B2 (en) 2002-01-03
PL341156A1 (en) 2001-03-26
DE59814003D1 (en) 2007-06-21
CZ20001962A3 (cs) 2002-01-16
RU2217431C2 (ru) 2003-11-27
ZA9810845B (en) 1999-05-26
AU1962599A (en) 1999-06-16
JP2001525325A (ja) 2001-12-11
SK7772000A3 (en) 2000-12-11
CA2311922A1 (en) 1999-06-10
EP1036078A1 (de) 2000-09-20
ID24571A (id) 2000-07-27

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