HK1038924A1 - 噻吩並嘧啶類 - Google Patents

噻吩並嘧啶類 Download PDF

Info

Publication number
HK1038924A1
HK1038924A1 HK02100600.0A HK02100600A HK1038924A1 HK 1038924 A1 HK1038924 A1 HK 1038924A1 HK 02100600 A HK02100600 A HK 02100600A HK 1038924 A1 HK1038924 A1 HK 1038924A1
Authority
HK
Hong Kong
Prior art keywords
pyrimidin
chloro
benzothieno
acid
formula
Prior art date
Application number
HK02100600.0A
Other languages
English (en)
Chinese (zh)
Inventor
R‧约纳斯
R‧約納斯
F‧-W‧克鲁克森
P‧舍林
F‧-W‧克魯克森
M‧克里斯塔德勒
P‧捨林
M‧克裏斯塔德勒
Original Assignee
默克专利股份公司
默克專利股份公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 默克专利股份公司, 默克專利股份公司 filed Critical 默克专利股份公司
Publication of HK1038924A1 publication Critical patent/HK1038924A1/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HK02100600.0A 1997-11-28 1998-11-19 噻吩並嘧啶類 HK1038924A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19752952A DE19752952A1 (de) 1997-11-28 1997-11-28 Thienopyrimidine
DE19752952.6 1997-11-28
PCT/EP1998/007436 WO1999028325A1 (de) 1997-11-28 1998-11-19 Thienopyrimidine

Publications (1)

Publication Number Publication Date
HK1038924A1 true HK1038924A1 (zh) 2002-04-04

Family

ID=7850200

Family Applications (1)

Application Number Title Priority Date Filing Date
HK02100600.0A HK1038924A1 (zh) 1997-11-28 1998-11-19 噻吩並嘧啶類

Country Status (24)

Country Link
US (2) US6420368B1 (https=)
EP (1) EP1036078B1 (https=)
JP (1) JP4314341B2 (https=)
KR (1) KR20010032445A (https=)
CN (1) CN1138780C (https=)
AR (1) AR010962A1 (https=)
AT (1) ATE361926T1 (https=)
AU (1) AU742433B2 (https=)
BR (1) BR9815409A (https=)
CA (1) CA2311922C (https=)
CO (1) CO4980884A1 (https=)
CZ (1) CZ291068B6 (https=)
DE (2) DE19752952A1 (https=)
ES (1) ES2285796T3 (https=)
HK (1) HK1038924A1 (https=)
HU (1) HUP0100488A3 (https=)
ID (1) ID24571A (https=)
NO (1) NO20002702D0 (https=)
PL (1) PL341156A1 (https=)
RU (1) RU2217431C2 (https=)
SK (1) SK7772000A3 (https=)
TW (1) TW472059B (https=)
WO (1) WO1999028325A1 (https=)
ZA (1) ZA9810845B (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19819023A1 (de) 1998-04-29 1999-11-04 Merck Patent Gmbh Thienopyrimidine
CN1346358A (zh) 1999-03-30 2002-04-24 日本曹达株式会社 噻吩并嘧啶化合物及其盐和制备方法
DE19942474A1 (de) * 1999-09-06 2001-03-15 Merck Patent Gmbh Pyrazolo[4,3-d]pyrimidine
US20020006926A1 (en) 2000-04-19 2002-01-17 Roylance H. H. Use of cyclic GMP-specific phosphodiesterase inhibitors for treatment of parkinson's disease
DE10031585A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 2-Aminoalkyl-thieno[2,3-d]pyrimidine
DE10031584A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 5-Aminoalkyl-pyrazolo[4,3-d]pyrimidine
DE10042997A1 (de) * 2000-09-01 2002-03-14 Merck Patent Gmbh Thienopyrimidine
CA2423981A1 (en) * 2000-09-29 2003-03-28 Kimiko Ichikawa Thienopyrimidine compounds and salts thereof and process for the preparation of the same
DE10058663A1 (de) * 2000-11-25 2002-05-29 Merck Patent Gmbh Verwendung von Thienopyrimidinen
AU2002227957A1 (en) * 2000-12-19 2002-07-01 Merck Patent Gmbh Pharmaceutical formulation containing thienopyrimidines and antithrombotics, calcium antagonists, prostaglandins or prostaglandin derivatives
DE10064994A1 (de) * 2000-12-23 2002-07-04 Merck Patent Gmbh Sulfamidothienopyrimidine
DE10103647A1 (de) 2001-01-27 2002-08-01 Merck Patent Gmbh Verfahren zur Herstellung eines Pyrazolo (4,3-d) pyrimidinderivates
HUP0302987A2 (hu) * 2001-01-31 2003-12-29 Merck Patent Gmbh Pirazolo [4,3-d] pirimidinszármazékokat vagy tienopirimidinszármazékokat és nitrátvegyületeket tartalmazó gyógyászati készítmények
MXPA03009925A (es) * 2001-04-30 2004-06-30 Bayer Pharmaceuticals Corp Nuevas tiofeno [2,3-d]pirimidinas 4-amino-5,6-sustituidas.
DE10148883A1 (de) * 2001-10-04 2003-04-10 Merck Patent Gmbh Pyrimidinderivate
JPWO2003035653A1 (ja) * 2001-10-26 2005-02-10 日本曹達株式会社 ピリドチエノピリミジン化合物およびその塩
OA13050A (en) 2003-04-29 2006-11-10 Pfizer Ltd 5,7-diaminopyrazolo [4,3-D] pyrimidines useful in the treatment of hypertension.
US7572799B2 (en) 2003-11-24 2009-08-11 Pfizer Inc Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors
CA2562251C (en) 2004-04-07 2009-04-28 Pfizer Inc. Pyrazolo'4,3-d pyrimidines
GB0420719D0 (en) * 2004-09-17 2004-10-20 Addex Pharmaceuticals Sa Novel allosteric modulators
ES2259891B1 (es) * 2004-11-30 2007-11-01 Laboratorios Almirall S.A. Nuevos derivados de piridotienopirimidina.
ES2259892B1 (es) * 2004-11-30 2007-11-01 Laboratorios Almirall S.A. Nuevos derivados de piridotienopirimidina.
AR088218A1 (es) 2011-07-19 2014-05-21 Infinity Pharmaceuticals Inc Compuestos heterociclicos utiles como inhibidores de pi3k
CN109297923A (zh) * 2018-09-19 2019-02-01 南通出入境检验检疫局检验检疫综合技术中心 纺织品中微量含氟整理剂的测定方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE245666C (https=)
DD245666A1 (de) * 1985-09-20 1987-05-13 Univ Halle Wittenberg Verfahren zur herstellung von 4-aminosubstituierten thieno 2,3-d-pyrimidin-2-ylessigsaeureestern
GB9311920D0 (en) * 1993-06-09 1993-07-28 Pfizer Ltd Therapeutic agents
US5869486A (en) * 1995-02-24 1999-02-09 Ono Pharmaceutical Co., Ltd. Fused pyrimidines and pyriazines as pharmaceutical compounds
DE19644228A1 (de) 1996-10-24 1998-04-30 Merck Patent Gmbh Thienopyrimidine

Also Published As

Publication number Publication date
CZ20001962A3 (cs) 2002-01-16
DE59814003D1 (en) 2007-06-21
WO1999028325A1 (de) 1999-06-10
ES2285796T3 (es) 2007-11-16
ZA9810845B (en) 1999-05-26
CZ291068B6 (cs) 2002-12-11
ID24571A (id) 2000-07-27
CN1306534A (zh) 2001-08-01
CA2311922C (en) 2009-09-29
JP2001525325A (ja) 2001-12-11
NO20002702L (no) 2000-05-26
RU2217431C2 (ru) 2003-11-27
CO4980884A1 (es) 2000-11-27
JP4314341B2 (ja) 2009-08-12
PL341156A1 (en) 2001-03-26
HUP0100488A3 (en) 2003-03-28
EP1036078B1 (de) 2007-05-09
AU1962599A (en) 1999-06-16
DE19752952A1 (de) 1999-06-02
SK7772000A3 (en) 2000-12-11
EP1036078A1 (de) 2000-09-20
CA2311922A1 (en) 1999-06-10
TW472059B (en) 2002-01-11
AR010962A1 (es) 2000-07-12
HUP0100488A2 (hu) 2001-09-28
AU742433B2 (en) 2002-01-03
KR20010032445A (ko) 2001-04-25
NO20002702D0 (no) 2000-05-26
US6420368B1 (en) 2002-07-16
ATE361926T1 (de) 2007-06-15
BR9815409A (pt) 2000-10-24
US20020132818A1 (en) 2002-09-19
CN1138780C (zh) 2004-02-18
US6495554B2 (en) 2002-12-17

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