HK1038230A1 - Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride - Google Patents

Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride

Info

Publication number
HK1038230A1
HK1038230A1 HK01107862A HK01107862A HK1038230A1 HK 1038230 A1 HK1038230 A1 HK 1038230A1 HK 01107862 A HK01107862 A HK 01107862A HK 01107862 A HK01107862 A HK 01107862A HK 1038230 A1 HK1038230 A1 HK 1038230A1
Authority
HK
Hong Kong
Prior art keywords
preparation
paroxetine hydrochloride
anhydrate form
crystalline anhydrate
crystalline
Prior art date
Application number
HK01107862A
Other languages
English (en)
Inventor
Victor Witold Jacewicz
Neal Ward
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9817196.0A external-priority patent/GB9817196D0/en
Priority claimed from GBGB9828777.4A external-priority patent/GB9828777D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of HK1038230A1 publication Critical patent/HK1038230A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445Non condensed piperidines, e.g. piperocaine
    • A61K31/4523Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4525Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/22Anxiolytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK01107862A 1998-08-07 2001-11-08 Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride HK1038230A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9817196.0A GB9817196D0 (en) 1998-08-07 1998-08-07 Novel process
GBGB9828777.4A GB9828777D0 (en) 1998-12-29 1998-12-29 Novel compounds
PCT/GB1999/002592 WO2000008017A1 (en) 1998-08-07 1999-08-06 Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride

Publications (1)

Publication Number Publication Date
HK1038230A1 true HK1038230A1 (en) 2002-03-08

Family

ID=26314179

Family Applications (1)

Application Number Title Priority Date Filing Date
HK01107862A HK1038230A1 (en) 1998-08-07 2001-11-08 Process for the preparation of a non-crystalline anhydrate form of paroxetine hydrochloride

Country Status (24)

Country Link
EP (2) EP1321465A3 (es)
JP (1) JP2002522434A (es)
KR (1) KR20010072323A (es)
CN (1) CN1321155A (es)
AP (2) AP2001002072A0 (es)
AT (1) ATE239016T1 (es)
AU (1) AU5428999A (es)
BG (1) BG105310A (es)
BR (1) BR9912858A (es)
CA (1) CA2339857A1 (es)
DE (1) DE69907467T2 (es)
DK (1) DK1100796T3 (es)
EA (1) EA200100221A1 (es)
ES (1) ES2198940T3 (es)
HK (1) HK1038230A1 (es)
HU (1) HUP0105466A3 (es)
ID (1) ID27914A (es)
IL (1) IL141286A0 (es)
NO (1) NO20010629L (es)
PL (1) PL345885A1 (es)
PT (1) PT1100796E (es)
SK (1) SK1972001A3 (es)
TR (1) TR200100444T2 (es)
WO (1) WO2000008017A1 (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1394160A1 (en) * 1996-06-13 2004-03-03 SUMIKA FINE CHEMICALS Co., Ltd. Process for preparing crystalline paroxetin hydrochloride
JP3796351B2 (ja) 1998-04-13 2006-07-12 住友化学株式会社 パロキセチン塩酸塩無水和物の乾燥方法
GB9923446D0 (en) * 1999-10-04 1999-12-08 Smithkline Beecham Plc Novel process
JP2005538031A (ja) * 2000-11-17 2005-12-15 イーライ・リリー・アンド・カンパニー ラクタム化合物
US8697094B2 (en) * 2002-10-16 2014-04-15 Takeda Pharmaceutical Company Limited Stable solid preparations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1422263A (en) * 1973-01-30 1976-01-21 Ferrosan As 4-phenyl-piperidine compounds
EP0223403B1 (en) * 1985-10-25 1993-08-04 Beecham Group Plc Piperidine derivative, its preparation, and its use as medicament
SK283608B6 (sk) * 1995-02-06 2003-10-07 Smithkline Beecham Plc Bezvodý hydrochlorid paroxetínu, spôsob jeho výroby a použitie
AP9901604A0 (en) * 1997-01-15 1999-09-30 Smithkline Beecham Plc Paroxetine compositions.
JP3796351B2 (ja) * 1998-04-13 2006-07-12 住友化学株式会社 パロキセチン塩酸塩無水和物の乾燥方法

Also Published As

Publication number Publication date
DK1100796T3 (da) 2003-08-25
ES2198940T3 (es) 2004-02-01
DE69907467T2 (de) 2004-03-11
PT1100796E (pt) 2003-09-30
EP1100796B1 (en) 2003-05-02
EP1321465A3 (en) 2003-09-03
ID27914A (id) 2001-05-03
IL141286A0 (en) 2002-03-10
PL345885A1 (en) 2002-01-14
CN1321155A (zh) 2001-11-07
AP0102072A0 (en) 2001-02-06
SK1972001A3 (en) 2001-08-06
CA2339857A1 (en) 2000-02-17
TR200100444T2 (tr) 2001-07-23
JP2002522434A (ja) 2002-07-23
HUP0105466A3 (en) 2002-11-28
EP1100796A1 (en) 2001-05-23
DE69907467D1 (de) 2003-06-05
BG105310A (en) 2001-12-29
EA200100221A1 (ru) 2001-08-27
ATE239016T1 (de) 2003-05-15
WO2000008017A1 (en) 2000-02-17
HUP0105466A2 (hu) 2002-05-29
AU5428999A (en) 2000-02-28
AP2001002072A0 (en) 2001-03-31
NO20010629L (no) 2001-03-20
KR20010072323A (ko) 2001-07-31
NO20010629D0 (no) 2001-02-06
BR9912858A (pt) 2001-11-20
EP1321465A2 (en) 2003-06-25

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20070806