HK1026851A1 - Dolastatin-15 derivatives in combination with taxanes. - Google Patents

Dolastatin-15 derivatives in combination with taxanes.

Info

Publication number
HK1026851A1
HK1026851A1 HK00106074A HK00106074A HK1026851A1 HK 1026851 A1 HK1026851 A1 HK 1026851A1 HK 00106074 A HK00106074 A HK 00106074A HK 00106074 A HK00106074 A HK 00106074A HK 1026851 A1 HK1026851 A1 HK 1026851A1
Authority
HK
Hong Kong
Prior art keywords
combination
dolastatin
taxanes
derivatives
compounds
Prior art date
Application number
HK00106074A
Other languages
English (en)
Inventor
Teresa Barlozzari
Andreas Haupt
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Publication of HK1026851A1 publication Critical patent/HK1026851A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
HK00106074A 1997-03-13 2000-09-26 Dolastatin-15 derivatives in combination with taxanes. HK1026851A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/819,101 US6103698A (en) 1997-03-13 1997-03-13 Dolastatin-15 derivatives in combination with taxanes
PCT/US1998/004594 WO1998040092A1 (en) 1997-03-13 1998-03-09 Dolastatin-15 derivatives in combination with taxanes

Publications (1)

Publication Number Publication Date
HK1026851A1 true HK1026851A1 (en) 2000-12-29

Family

ID=25227196

Family Applications (1)

Application Number Title Priority Date Filing Date
HK00106074A HK1026851A1 (en) 1997-03-13 2000-09-26 Dolastatin-15 derivatives in combination with taxanes.

Country Status (30)

Country Link
US (2) US6103698A (pt)
EP (1) EP0981358B1 (pt)
JP (1) JP2001514659A (pt)
KR (1) KR100555604B1 (pt)
CN (1) CN1157223C (pt)
AT (1) ATE241376T1 (pt)
AU (1) AU728027B2 (pt)
BG (1) BG64338B1 (pt)
BR (1) BR9808249A (pt)
CA (1) CA2282720C (pt)
CO (1) CO4940498A1 (pt)
CZ (1) CZ293905B6 (pt)
DE (1) DE69815100T2 (pt)
DK (1) DK0981358T3 (pt)
ES (1) ES2200317T3 (pt)
HK (1) HK1026851A1 (pt)
HR (1) HRP980125A2 (pt)
HU (1) HU228860B1 (pt)
ID (1) ID23900A (pt)
IL (2) IL131597A0 (pt)
NO (1) NO323894B1 (pt)
NZ (1) NZ337416A (pt)
PL (1) PL197834B1 (pt)
PT (1) PT981358E (pt)
RU (1) RU2218174C2 (pt)
SK (1) SK285133B6 (pt)
TR (1) TR199902244T2 (pt)
TW (1) TWI277426B (pt)
WO (1) WO1998040092A1 (pt)
ZA (1) ZA982093B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010009901A1 (en) 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
WO2001024763A2 (en) 1999-10-01 2001-04-12 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
WO2002038164A1 (en) * 2000-11-08 2002-05-16 Lorus Therapeutics Inc. Combination preparation of a biological response modifier and an anticancer agent and uses thereof
US20050192443A1 (en) * 2000-11-08 2005-09-01 Lorus Therapeutics Inc. Biological response modifier for the treatment of cancer
WO2006122408A1 (en) 2005-05-18 2006-11-23 Aegera Therapeutics Inc. Bir domain binding compounds
NZ572836A (en) 2006-05-16 2011-12-22 Pharmascience Inc Iap bir domain binding compounds
KR20130009760A (ko) 2010-02-10 2013-01-23 이뮤노젠 아이엔씨 Ｃｄ２０ 항체 및 이의 용도
EP2534170B1 (en) 2010-02-12 2017-04-19 Pharmascience Inc. Iap bir domain binding compounds
US20230295221A1 (en) * 2020-06-03 2023-09-21 Chugai Seiyaku Kabushiki Kaisha Efficient peptide condensation method for difficult sequences
CA3230737A1 (en) 2021-09-03 2023-03-09 Toray Industries, Inc. Pharmaceutical composition for cancer treatment and/or prevention

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816444A (en) * 1987-07-10 1989-03-28 Arizona Board Of Regents, Arizona State University Cell growth inhibitory substance
US5676978A (en) 1989-02-14 1997-10-14 Amira, Inc. Methods of inhibiting undesirable cell growth using a combination of a cyclocreatine compound and a hyperplastic inhibitory agent
US4879278A (en) 1989-05-16 1989-11-07 Arizona Board Of Regents Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
US5278324A (en) * 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
DK0598129T3 (da) 1991-08-09 2000-07-03 Teikoku Hormone Mfg Co Ltd Nye tetrapeptidderivater
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
FR2688518B1 (fr) * 1992-03-13 1994-05-06 Rhone Poulenc Rorer Sa Procede de preparation de derives du taxane.
US5831002A (en) * 1992-05-20 1998-11-03 Basf Aktiengesellschaft Antitumor peptides
US5248796A (en) * 1992-06-18 1993-09-28 Bristol-Myers Squibb Company Taxol derivatives
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
FR2697752B1 (fr) * 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
EP0674652B1 (en) * 1992-12-16 2000-09-13 Basf Aktiengesellschaft Dolastatin analog
US5484612A (en) * 1993-09-22 1996-01-16 The Board Of Trustees Of The Leland Stanford Junior University Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin
CA2129282A1 (en) 1993-09-29 1995-03-30 George Weber Method for the treatment of neoplastic disease utilizing taxol and tiazofurin
US5447936A (en) * 1993-12-22 1995-09-05 Bionumerik Pharmaceuticals, Inc. Lactone stable formulation of 10-hydroxy 7-ethyl camptothecin and methods for uses thereof
US5565478A (en) * 1994-03-14 1996-10-15 The United States Of America As Represented By The Department Of Health & Human Services Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs
US5494930A (en) * 1994-06-02 1996-02-27 Shimizu; Yuzuru Caribenolide I
US5525613A (en) * 1994-06-16 1996-06-11 Entropin, Inc. Covalently coupled benzoylecgonine ecgonine and ecgonidine
US5530097A (en) * 1994-08-01 1996-06-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory peptide amides
US5504191A (en) * 1994-08-01 1996-04-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide methyl esters
US5543423A (en) * 1994-11-16 1996-08-06 Vertex Pharmaceuticals, Incorporated Amino acid derivatives with improved multi-drug resistance activity
WO1996018401A1 (en) 1994-12-15 1996-06-20 Baker Norton Pharmaceuticals, Inc. Method and composition for reducing tumor development with a combination of a taxane compound and a tellurium and/or selenium compound

Also Published As

Publication number Publication date
EP0981358A1 (en) 2000-03-01
CZ321199A3 (cs) 2000-02-16
SK285133B6 (sk) 2006-07-07
DE69815100T2 (de) 2004-02-05
KR20000076211A (ko) 2000-12-26
CO4940498A1 (es) 2000-07-24
TWI277426B (en) 2007-04-01
US6632795B1 (en) 2003-10-14
AU6694598A (en) 1998-09-29
NO994408D0 (no) 1999-09-10
NZ337416A (en) 2001-05-25
ID23900A (id) 2000-05-25
EP0981358B1 (en) 2003-05-28
AU728027B2 (en) 2001-01-04
ES2200317T3 (es) 2004-03-01
CA2282720A1 (en) 1998-09-17
CZ293905B6 (cs) 2004-08-18
HUP0001381A3 (en) 2001-12-28
US6103698A (en) 2000-08-15
ZA982093B (en) 1999-09-12
CA2282720C (en) 2009-12-29
CN1157223C (zh) 2004-07-14
PL335579A1 (en) 2000-05-08
NO323894B1 (no) 2007-07-16
KR100555604B1 (ko) 2006-03-03
IL131597A0 (en) 2001-01-28
BG64338B1 (bg) 2004-10-29
ATE241376T1 (de) 2003-06-15
DE69815100D1 (de) 2003-07-03
WO1998040092A1 (en) 1998-09-17
JP2001514659A (ja) 2001-09-11
BG103728A (en) 2000-04-28
HU228860B1 (en) 2013-06-28
SK125199A3 (en) 2000-08-14
RU2218174C2 (ru) 2003-12-10
DK0981358T3 (da) 2003-09-22
TR199902244T2 (xx) 1999-12-21
NO994408L (no) 1999-11-10
IL131597A (en) 2006-06-11
HRP980125A2 (en) 1999-02-28
PL197834B1 (pl) 2008-04-30
BR9808249A (pt) 2000-05-16
HUP0001381A2 (hu) 2000-10-28
CN1252728A (zh) 2000-05-10
PT981358E (pt) 2003-09-30

Similar Documents

Publication Publication Date Title
EP1181013A4 (en) METHOD AND COMPOSITION FOR TREATING CANCER
CY1105399T1 (el) Μεθοδος επιλεκτικης υποκαταστασεως των ταξανων
RS20080167A (en) Novel improved compositions for cancer therapy
NZ245795A (en) The use of paclitaxel formulations with reduced haematologic toxicity to treat tumours
ZA991885B (en) Novel methods and compositions for delivery of taxanes.
FI943749A (fi) Taksaanijohdannaisten fosfono-oksimetyylieetterit
FI935821A0 (fi) Fosfonooximetylestrar av taxanderivat
WO2002058694A3 (en) Method of treating hematologic tumors and cancers using beta lapachone
AU2412695A (en) Taxane class derivative based pharmaceutical compositions
HK1026851A1 (en) Dolastatin-15 derivatives in combination with taxanes.
CY1110449T1 (el) Συνδυασμος δοκεταξελης και φλαβοπιριδinολης
ATE554753T1 (de) 2,2'-dithio-bis(ethansulfonat) für den einsatz zur hemmung paclitaxel-induzierter abnormer thermoesthesia
DE69430797D1 (de) C9 taxanderivate und diese enthaltende pharmazeutische zusammensetzungen
WO2002078690A3 (en) Taxoid anti-tumor agents and pharmaceutical compositions thereof
ATE393624T1 (de) Verwendung von sesquiterpene enthaltenden zusammenstellungen zur behandlung von krebs
PL350331A1 (en) C10 carbamoyloxy substituted taxanes as antitumor agents
AU4558201A (en) Taxane anticancer agents
EP0793499A4 (en) METHOD AND MEANS FOR REDUCING TUMOR DEVELOPMENT BY MEANS OF A COMBINATION OF A TAXAN COMPOUND AND A TELLUR AND / OR SELENIUM COMPOUND
SI1287854T1 (sl) Kombinacija DMXAA in paklitaksela ali docetakselaproti raku
HUP0103246A2 (hu) C10 karbonát szubsztituált taxánok
CA2206567A1 (en) Method and composition for reducing tumor development with a combination of a taxane compound and a tellurium and/or selenium compound
HUP0103247A2 (hu) C7 észter szubsztituált taxánok

Legal Events

Date Code Title Description
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20140309