DK0981358T3 - Dolastatin-15-derivater i kombinationer med taxaner - Google Patents

Dolastatin-15-derivater i kombinationer med taxaner

Info

Publication number
DK0981358T3
DK0981358T3 DK98909066T DK98909066T DK0981358T3 DK 0981358 T3 DK0981358 T3 DK 0981358T3 DK 98909066 T DK98909066 T DK 98909066T DK 98909066 T DK98909066 T DK 98909066T DK 0981358 T3 DK0981358 T3 DK 0981358T3
Authority
DK
Denmark
Prior art keywords
dolastatin
taxanes
derivatives
combinations
compounds
Prior art date
Application number
DK98909066T
Other languages
Danish (da)
English (en)
Inventor
Teresa Barlozzari
Andreas Haupt
Original Assignee
Abbott Gmbh & Co Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Gmbh & Co Kg filed Critical Abbott Gmbh & Co Kg
Application granted granted Critical
Publication of DK0981358T3 publication Critical patent/DK0981358T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Epoxy Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK98909066T 1997-03-13 1998-03-09 Dolastatin-15-derivater i kombinationer med taxaner DK0981358T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/819,101 US6103698A (en) 1997-03-13 1997-03-13 Dolastatin-15 derivatives in combination with taxanes
PCT/US1998/004594 WO1998040092A1 (en) 1997-03-13 1998-03-09 Dolastatin-15 derivatives in combination with taxanes

Publications (1)

Publication Number Publication Date
DK0981358T3 true DK0981358T3 (da) 2003-09-22

Family

ID=25227196

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98909066T DK0981358T3 (da) 1997-03-13 1998-03-09 Dolastatin-15-derivater i kombinationer med taxaner

Country Status (30)

Country Link
US (2) US6103698A (pt)
EP (1) EP0981358B1 (pt)
JP (1) JP2001514659A (pt)
KR (1) KR100555604B1 (pt)
CN (1) CN1157223C (pt)
AT (1) ATE241376T1 (pt)
AU (1) AU728027B2 (pt)
BG (1) BG64338B1 (pt)
BR (1) BR9808249A (pt)
CA (1) CA2282720C (pt)
CO (1) CO4940498A1 (pt)
CZ (1) CZ293905B6 (pt)
DE (1) DE69815100T2 (pt)
DK (1) DK0981358T3 (pt)
ES (1) ES2200317T3 (pt)
HK (1) HK1026851A1 (pt)
HR (1) HRP980125A2 (pt)
HU (1) HU228860B1 (pt)
ID (1) ID23900A (pt)
IL (2) IL131597A0 (pt)
NO (1) NO323894B1 (pt)
NZ (1) NZ337416A (pt)
PL (1) PL197834B1 (pt)
PT (1) PT981358E (pt)
RU (1) RU2218174C2 (pt)
SK (1) SK285133B6 (pt)
TR (1) TR199902244T2 (pt)
TW (1) TWI277426B (pt)
WO (1) WO1998040092A1 (pt)
ZA (1) ZA982093B (pt)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010009901A1 (en) * 1996-12-11 2001-07-26 Basf Aktiengesellschaft Germany Antineoplastic peptides
EP1229934B1 (en) 1999-10-01 2014-03-05 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
WO2002038164A1 (en) * 2000-11-08 2002-05-16 Lorus Therapeutics Inc. Combination preparation of a biological response modifier and an anticancer agent and uses thereof
US20050192443A1 (en) * 2000-11-08 2005-09-01 Lorus Therapeutics Inc. Biological response modifier for the treatment of cancer
CA2607940C (en) 2005-05-18 2009-12-15 Aegera Therapeutics Inc. Bir domain binding compounds
KR101506466B1 (ko) 2006-05-16 2015-03-27 파마사이언스 인크. Ｉａｐ ｂｉｒ 도메인 결합 화합물
TW201129384A (en) 2010-02-10 2011-09-01 Immunogen Inc CD20 antibodies and uses thereof
RU2567544C2 (ru) 2010-02-12 2015-11-10 Фармасайенс Инк. Bir домен iap связывающие соединения
KR20230019120A (ko) * 2020-06-03 2023-02-07 추가이 세이야쿠 가부시키가이샤 고난도 서열의 효율적 펩티드 축합법
WO2023033129A1 (ja) 2021-09-03 2023-03-09 東レ株式会社 癌の治療及び／又は予防用医薬組成物

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816444A (en) * 1987-07-10 1989-03-28 Arizona Board Of Regents, Arizona State University Cell growth inhibitory substance
US5676978A (en) 1989-02-14 1997-10-14 Amira, Inc. Methods of inhibiting undesirable cell growth using a combination of a cyclocreatine compound and a hyperplastic inhibitory agent
US4879278A (en) 1989-05-16 1989-11-07 Arizona Board Of Regents Isolation and structural elucidation of the cytostatic linear depsipeptide dolastatin 15
US5278324A (en) * 1990-08-28 1994-01-11 Virginia Tech Intellectual Properties, Inc. Water soluble derivatives of taxol
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
WO1993003054A1 (en) 1991-08-09 1993-02-18 Teikoku Hormone Mfg. Co., Ltd. Novel tetrapeptide derivative
US5227400A (en) * 1991-09-23 1993-07-13 Florida State University Furyl and thienyl substituted taxanes and pharmaceutical compositions containing them
US5250683A (en) * 1991-09-23 1993-10-05 Florida State University Certain substituted taxanes and pharmaceutical compositions containing them
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
FR2688518B1 (fr) * 1992-03-13 1994-05-06 Rhone Poulenc Rorer Sa Procede de preparation de derives du taxane.
US5831002A (en) * 1992-05-20 1998-11-03 Basf Aktiengesellschaft Antitumor peptides
US5248796A (en) * 1992-06-18 1993-09-28 Bristol-Myers Squibb Company Taxol derivatives
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
FR2697752B1 (fr) * 1992-11-10 1995-04-14 Rhone Poulenc Rorer Sa Compositions antitumorales contenant des dérivés du taxane.
EP0674652B1 (en) * 1992-12-16 2000-09-13 Basf Aktiengesellschaft Dolastatin analog
US5484612A (en) * 1993-09-22 1996-01-16 The Board Of Trustees Of The Leland Stanford Junior University Method of treating a mammal having a solid tumor susceptible to treatment with cisplatin
CA2129282A1 (en) 1993-09-29 1995-03-30 George Weber Method for the treatment of neoplastic disease utilizing taxol and tiazofurin
US5447936A (en) * 1993-12-22 1995-09-05 Bionumerik Pharmaceuticals, Inc. Lactone stable formulation of 10-hydroxy 7-ethyl camptothecin and methods for uses thereof
US5565478A (en) * 1994-03-14 1996-10-15 The United States Of America As Represented By The Department Of Health & Human Services Combination therapy using signal transduction inhibitors with paclitaxel and other taxane analogs
US5494930A (en) * 1994-06-02 1996-02-27 Shimizu; Yuzuru Caribenolide I
US5525613A (en) * 1994-06-16 1996-06-11 Entropin, Inc. Covalently coupled benzoylecgonine ecgonine and ecgonidine
US5504191A (en) * 1994-08-01 1996-04-02 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory pentapeptide methyl esters
US5530097A (en) * 1994-08-01 1996-06-25 Arizona Board Of Regents Acting On Behalf Of Arizona State University Human cancer inhibitory peptide amides
US5543423A (en) * 1994-11-16 1996-08-06 Vertex Pharmaceuticals, Incorporated Amino acid derivatives with improved multi-drug resistance activity
DE69534535T2 (de) 1994-12-15 2006-07-06 Baker Norton Pharmaceuticals, Inc., Miami Verfahren und mittel zur verminderung der tumorentwicklung mittels einer kombination aus einer taxanverbindung und einer tellur und/oder selenverbindung

Also Published As

Publication number Publication date
DE69815100T2 (de) 2004-02-05
US6103698A (en) 2000-08-15
WO1998040092A1 (en) 1998-09-17
PL197834B1 (pl) 2008-04-30
HUP0001381A3 (en) 2001-12-28
HU228860B1 (en) 2013-06-28
IL131597A (en) 2006-06-11
EP0981358B1 (en) 2003-05-28
ID23900A (id) 2000-05-25
SK125199A3 (en) 2000-08-14
ZA982093B (en) 1999-09-12
NZ337416A (en) 2001-05-25
HRP980125A2 (en) 1999-02-28
CZ293905B6 (cs) 2004-08-18
CO4940498A1 (es) 2000-07-24
SK285133B6 (sk) 2006-07-07
PL335579A1 (en) 2000-05-08
NO994408D0 (no) 1999-09-10
NO994408L (no) 1999-11-10
HK1026851A1 (en) 2000-12-29
KR20000076211A (ko) 2000-12-26
ES2200317T3 (es) 2004-03-01
CN1252728A (zh) 2000-05-10
US6632795B1 (en) 2003-10-14
AU6694598A (en) 1998-09-29
EP0981358A1 (en) 2000-03-01
HUP0001381A2 (hu) 2000-10-28
TWI277426B (en) 2007-04-01
IL131597A0 (en) 2001-01-28
KR100555604B1 (ko) 2006-03-03
AU728027B2 (en) 2001-01-04
CA2282720C (en) 2009-12-29
CN1157223C (zh) 2004-07-14
NO323894B1 (no) 2007-07-16
CA2282720A1 (en) 1998-09-17
ATE241376T1 (de) 2003-06-15
DE69815100D1 (de) 2003-07-03
PT981358E (pt) 2003-09-30
TR199902244T2 (xx) 1999-12-21
BR9808249A (pt) 2000-05-16
CZ321199A3 (cs) 2000-02-16
BG64338B1 (bg) 2004-10-29
BG103728A (en) 2000-04-28
RU2218174C2 (ru) 2003-12-10
JP2001514659A (ja) 2001-09-11

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