HK1019336A1 - Process for preparation of pyrimidine derivatives - Google Patents
Process for preparation of pyrimidine derivativesInfo
- Publication number
- HK1019336A1 HK1019336A1 HK99104379A HK99104379A HK1019336A1 HK 1019336 A1 HK1019336 A1 HK 1019336A1 HK 99104379 A HK99104379 A HK 99104379A HK 99104379 A HK99104379 A HK 99104379A HK 1019336 A1 HK1019336 A1 HK 1019336A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- pct
- preparation
- formula
- represented
- sec
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019960014539A KR0177293B1 (ko) | 1996-05-04 | 1996-05-04 | 신규의 피리미딘 유도체 및 그의 제조방법 |
KR1019960014538A KR0177294B1 (ko) | 1996-05-04 | 1996-05-04 | 피리미딘 유도체의 제조방법 |
KR1019960049382A KR100209587B1 (ko) | 1996-10-29 | 1996-10-29 | 피리미딘 유도체의 제조방법 |
KR1019960049381A KR100193080B1 (ko) | 1996-10-29 | 1996-10-29 | (r)-피리미딘 유도체의 제조방법 |
KR1019960049380A KR0185292B1 (ko) | 1996-10-29 | 1996-10-29 | (s)-피리미딘 유도체의 제조방법 |
PCT/KR1997/000073 WO1997042186A1 (en) | 1996-05-04 | 1997-04-30 | Process for preparation of pyrimidine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
HK1019336A1 true HK1019336A1 (en) | 2000-02-03 |
Family
ID=27532197
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HK99104379A HK1019336A1 (en) | 1996-05-04 | 1999-10-07 | Process for preparation of pyrimidine derivatives |
Country Status (14)
Country | Link |
---|---|
US (1) | US5990311A (da) |
EP (1) | EP0900214B1 (da) |
JP (2) | JP3160297B2 (da) |
CN (2) | CN1190427C (da) |
AT (1) | ATE206117T1 (da) |
AU (1) | AU712970B2 (da) |
CA (2) | CA2253906C (da) |
DE (1) | DE69706981T2 (da) |
DK (1) | DK0900214T3 (da) |
ES (1) | ES2165052T3 (da) |
HK (1) | HK1019336A1 (da) |
PT (1) | PT900214E (da) |
RU (1) | RU2174978C2 (da) |
WO (1) | WO1997042186A1 (da) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IN188411B (da) * | 1997-03-27 | 2002-09-21 | Yuhan Corp | |
KR100272471B1 (ko) * | 1998-11-17 | 2000-11-15 | 김선진 | 신규의 피리미딘 유도체 및 그의 제조방법 |
US6852739B1 (en) * | 1999-02-26 | 2005-02-08 | Nitromed Inc. | Methods using proton pump inhibitors and nitric oxide donors |
GB0110338D0 (en) * | 2001-04-27 | 2001-06-20 | Sb Pharmco Inc | Novel processes |
US7211590B2 (en) * | 2002-08-01 | 2007-05-01 | Nitromed, Inc. | Nitrosated proton pump inhibitors, compositions and methods of use |
US7776873B2 (en) * | 2005-12-01 | 2010-08-17 | Yuhan Corporation | Method for treating damage to gastric mucosa |
EP1965774A2 (en) * | 2005-12-30 | 2008-09-10 | Cogentus Pharmaceuticals, Inc. | Oral pharmaceutical formulations containing non-steroidal anti-inflammatory drugs and acid inhibitors |
JP5844028B2 (ja) | 2006-04-04 | 2016-01-13 | ケージー アクキュイシチオン エルエルシー | 抗血小板薬及び酸阻害薬を含む経口剤形 |
CN102863423B (zh) * | 2011-07-04 | 2014-09-17 | 天津药物研究院 | 一种制备异喹啉基取代的嘧啶衍生物的方法 |
CN105601611A (zh) * | 2014-11-19 | 2016-05-25 | 江苏天士力帝益药业有限公司 | 一种盐酸洛氟普啶多晶型物及其制备方法 |
CN105669642B (zh) * | 2014-11-19 | 2020-06-09 | 江苏天士力帝益药业有限公司 | 一种盐酸洛氟普啶的制备方法 |
CN105399727A (zh) * | 2015-12-02 | 2016-03-16 | 芷威(上海)化学科技有限公司 | 盐酸瑞伐拉赞新结晶形态 |
CN106995432A (zh) * | 2016-01-25 | 2017-08-01 | 广东华南药业集团有限公司 | 一种瑞普拉生无水合物晶型及其制备方法和用途 |
CN106995431A (zh) * | 2016-01-25 | 2017-08-01 | 广东华南药业集团有限公司 | 一种瑞普拉生水合物晶型及其制备方法和用途 |
CN107759562B (zh) * | 2016-08-21 | 2020-10-23 | 常州四药制药有限公司 | 一种盐酸洛氟普啶的制备方法 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4755218A (en) * | 1985-12-31 | 1988-07-05 | Monsanto Company | Haloacyl 1-substituted-1,2,3,4-tetrahydro-isoquinolines as herbicide antidotes |
US4966622A (en) * | 1988-04-12 | 1990-10-30 | Ciba-Geigy Corporation | N-phenyl-N-pyrimidin-2-ylureas |
GB9012592D0 (en) * | 1990-06-06 | 1990-07-25 | Smithkline Beecham Intercredit | Compounds |
US5276186A (en) * | 1992-03-11 | 1994-01-04 | Ciba-Geigy Corporation | Process for the production of guanidine derivatives |
KR0144833B1 (ko) * | 1992-12-28 | 1998-07-15 | 김태훈 | 신규의 퀴나졸린 유도체 및 그의 제조방법 |
CA2197298C (en) * | 1994-08-13 | 1999-10-19 | Jong Wook Lee | Novel pyrimidine derivatives and processes for the preparation thereof |
-
1997
- 1997-04-30 CN CNB021247854A patent/CN1190427C/zh not_active Expired - Lifetime
- 1997-04-30 ES ES97920966T patent/ES2165052T3/es not_active Expired - Lifetime
- 1997-04-30 EP EP97920966A patent/EP0900214B1/en not_active Expired - Lifetime
- 1997-04-30 CA CA002253906A patent/CA2253906C/en not_active Expired - Fee Related
- 1997-04-30 PT PT97920966T patent/PT900214E/pt unknown
- 1997-04-30 DE DE69706981T patent/DE69706981T2/de not_active Expired - Lifetime
- 1997-04-30 DK DK97920966T patent/DK0900214T3/da active
- 1997-04-30 WO PCT/KR1997/000073 patent/WO1997042186A1/en active IP Right Grant
- 1997-04-30 US US09/171,579 patent/US5990311A/en not_active Expired - Lifetime
- 1997-04-30 JP JP53975697A patent/JP3160297B2/ja not_active Expired - Fee Related
- 1997-04-30 RU RU98121687/04A patent/RU2174978C2/ru not_active IP Right Cessation
- 1997-04-30 CA CA002358479A patent/CA2358479C/en not_active Expired - Fee Related
- 1997-04-30 AU AU27133/97A patent/AU712970B2/en not_active Ceased
- 1997-04-30 AT AT97920966T patent/ATE206117T1/de active
- 1997-04-30 CN CN97194367A patent/CN1097591C/zh not_active Expired - Lifetime
-
1999
- 1999-10-07 HK HK99104379A patent/HK1019336A1/xx not_active IP Right Cessation
-
2000
- 2000-06-30 JP JP2000198538A patent/JP2001055379A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0900214B1 (en) | 2001-09-26 |
EP0900214A1 (en) | 1999-03-10 |
DE69706981T2 (de) | 2002-06-06 |
US5990311A (en) | 1999-11-23 |
CN1425655A (zh) | 2003-06-25 |
AU712970B2 (en) | 1999-11-18 |
AU2713397A (en) | 1997-11-26 |
CA2253906C (en) | 2002-04-02 |
CA2358479A1 (en) | 1997-11-13 |
DE69706981D1 (de) | 2001-10-31 |
JPH11509237A (ja) | 1999-08-17 |
RU2174978C2 (ru) | 2001-10-20 |
JP2001055379A (ja) | 2001-02-27 |
ATE206117T1 (de) | 2001-10-15 |
WO1997042186A1 (en) | 1997-11-13 |
DK0900214T3 (da) | 2002-01-28 |
CA2358479C (en) | 2004-07-13 |
CN1097591C (zh) | 2003-01-01 |
PT900214E (pt) | 2002-03-28 |
CN1217722A (zh) | 1999-05-26 |
CA2253906A1 (en) | 1997-11-13 |
JP3160297B2 (ja) | 2001-04-25 |
ES2165052T3 (es) | 2002-03-01 |
CN1190427C (zh) | 2005-02-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PF | Patent in force | ||
PE | Patent expired |
Effective date: 20170429 |