HK1015609A1 - Pyrrolopyridazine derivative - Google Patents

Pyrrolopyridazine derivative

Info

Publication number
HK1015609A1
HK1015609A1 HK98112609A HK98112609A HK1015609A1 HK 1015609 A1 HK1015609 A1 HK 1015609A1 HK 98112609 A HK98112609 A HK 98112609A HK 98112609 A HK98112609 A HK 98112609A HK 1015609 A1 HK1015609 A1 HK 1015609A1
Authority
HK
Hong Kong
Prior art keywords
group
alkyl group
aryl
halogeno
cycloalkyl
Prior art date
Application number
HK98112609A
Other languages
English (en)
Inventor
Tomio Kimura
Yoshimi Fujihara
Nobuhiko Shibakawa
Hiroshi Fujiwara
Etsuro Itoh
Keiji Matsunobu
Keiichi Tabata
Hiroshi Yasuda
Original Assignee
Sankyo Co
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co, Ube Industries filed Critical Sankyo Co
Publication of HK1015609A1 publication Critical patent/HK1015609A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
HK98112609A 1994-01-19 1998-12-01 Pyrrolopyridazine derivative HK1015609A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP398894 1994-01-19
PCT/JP1995/000038 WO1995019980A1 (fr) 1994-01-19 1995-01-18 Derive de pyrrolopyridazine

Publications (1)

Publication Number Publication Date
HK1015609A1 true HK1015609A1 (en) 1999-10-15

Family

ID=11572411

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98112609A HK1015609A1 (en) 1994-01-19 1998-12-01 Pyrrolopyridazine derivative

Country Status (19)

Country Link
US (1) US6063782A (da)
EP (1) EP0742218B1 (da)
KR (1) KR100361199B1 (da)
CN (1) CN1044811C (da)
AT (1) ATE229020T1 (da)
AU (1) AU680998B2 (da)
CZ (1) CZ283216B6 (da)
DE (1) DE69529056T2 (da)
DK (1) DK0742218T3 (da)
ES (1) ES2185693T3 (da)
FI (1) FI112488B (da)
HK (1) HK1015609A1 (da)
HU (1) HU225920B1 (da)
MX (1) MX9602850A (da)
NO (1) NO307300B1 (da)
NZ (1) NZ278675A (da)
PT (1) PT742218E (da)
RU (1) RU2146257C1 (da)
WO (1) WO1995019980A1 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316429B1 (en) * 1997-05-07 2001-11-13 Sugen, Inc. Bicyclic protein kinase inhibitors
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds
DE19836698A1 (de) * 1998-08-13 2000-02-17 Bayer Ag Verfahren zur Herstellung von fluorierten Benzylalkoholen und -aldehyden
TWI287014B (en) 1999-06-15 2007-09-21 Sankyo Co Optically active pyrrolopyridazine compound
MXPA02007799A (es) 2000-02-10 2002-10-17 Sankyo Co Compuesto de pirrolopiridazina.
FR2849025B1 (fr) * 2002-12-20 2005-10-14 Rhodia Chimie Sa Esters d'allyle substitue par un groupe difluoromethylene, leur procede de synthese et leur utilisation
JP2003119140A (ja) * 2001-08-08 2003-04-23 Sankyo Co Ltd ピロロピリダジン化合物を含有する医薬
BRPI0213586B1 (pt) * 2001-09-27 2017-06-20 Monsanto Technology Llc Compositions, method of protecting a plant or its propagation materials against fungus disease or damage, as a controlled release formulation
WO2004029057A1 (ja) * 2002-09-25 2004-04-08 Sankyo Company, Limited 内臓痛の治療または予防のための医薬組成物
WO2004029058A1 (ja) * 2002-09-25 2004-04-08 Sankyo Company, Limited 血中ガストリン濃度上昇の抑制のための医薬組成物
EP1611901B1 (en) * 2003-03-13 2013-07-10 Eisai R&D Management Co., Ltd. Preventive or remedy for teeth grinding
ES2342478T3 (es) * 2004-09-03 2010-07-07 Yuhan Corporation Derivados de pirrolo(3,2-c)piridina y procedimiento para la preparacion de los mismos.
PL1784402T3 (pl) * 2004-09-03 2011-12-30 Yuhan Corp Pochodne pirolo[3,2-c]pirydyny oraz sposoby ich wytwarzania
ES2426920T3 (es) * 2004-09-03 2013-10-25 Yuhan Corporation Derivados de pirrolo[3,2-B]piridina y procesos para su preparación
KR101137168B1 (ko) * 2005-03-09 2012-04-19 주식회사유한양행 피롤로［２,３-ｄ］피리다진 유도체 및 그의 제조방법
WO2007081030A1 (ja) * 2006-01-16 2007-07-19 Ube Industries, Ltd. ピロロピリダジノン化合物
CN101003537A (zh) * 2006-01-17 2007-07-25 上海恒瑞医药有限公司 吡咯并哒嗪类衍生物及其制备方法和用途
AU2011210765A1 (en) 2010-01-28 2012-09-13 President And Fellows Of Harvard College Compositions and methods for enhancing proteasome activity
RS58718B1 (sr) 2011-05-12 2019-06-28 Proteostasis Therapeutics Inc Regulatori proteostaze
WO2014116228A1 (en) 2013-01-25 2014-07-31 President And Fellows Of Harvard College Usp14 inhibitors for treating or preventing viral infections
WO2015073528A1 (en) 2013-11-12 2015-05-21 Proteostasis Therapeutics, Inc. Proteasome activity enhancing compounds
ES2825798T3 (es) * 2015-01-13 2021-05-17 Vivreon Biosciences Llc Moduladores de canales de Ca2+ activados por liberación de Ca2+ (CRAC) y usos farmacéuticos de los mismos

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901430D0 (en) * 1989-01-23 1989-03-15 Smithkline Beckman Intercredit Compounds
AU7754691A (en) * 1990-04-27 1991-11-27 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel pyridazines
US5068332A (en) * 1990-10-12 1991-11-26 American Home Products Corporation Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
WO1992006979A1 (de) * 1990-10-15 1992-04-30 Byk Gulden Lomberg Chemische Fabrik Gmbh Neue diazine
US5534515A (en) * 1991-10-25 1996-07-09 Byk Gulden Lomberg Chemische Fabrik Gmbh Pyrrolopyridazines having gastrointestinal protective effects

Also Published As

Publication number Publication date
HUT77998A (hu) 1999-04-28
MX9602850A (es) 1997-06-28
ATE229020T1 (de) 2002-12-15
FI112488B (fi) 2003-12-15
DK0742218T3 (da) 2003-01-13
AU680998B2 (en) 1997-08-14
EP0742218B1 (en) 2002-12-04
PT742218E (pt) 2003-02-28
US6063782A (en) 2000-05-16
CN1143964A (zh) 1997-02-26
NO962998L (no) 1996-09-17
EP0742218A4 (en) 1997-07-09
DE69529056T2 (de) 2003-11-13
RU2146257C1 (ru) 2000-03-10
AU1465795A (en) 1995-08-08
ES2185693T3 (es) 2003-05-01
FI962892A (fi) 1996-09-16
FI962892A0 (fi) 1996-07-18
HU9601967D0 (en) 1996-09-30
NO307300B1 (no) 2000-03-13
WO1995019980A1 (fr) 1995-07-27
KR100361199B1 (ko) 2003-04-16
CZ208496A3 (en) 1996-12-11
EP0742218A1 (en) 1996-11-13
CN1044811C (zh) 1999-08-25
NO962998D0 (no) 1996-07-18
DE69529056D1 (de) 2003-01-16
CZ283216B6 (cs) 1998-02-18
HU225920B1 (en) 2008-01-28
NZ278675A (en) 1997-07-27

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20090118