FI112488B - Aryylialkyyli- tai heteroaryylialkyylisubstituoidut pyrrolopyridatsiinijohdannaiset - Google Patents

Aryylialkyyli- tai heteroaryylialkyylisubstituoidut pyrrolopyridatsiinijohdannaiset Download PDF

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Publication number
FI112488B
FI112488B FI962892A FI962892A FI112488B FI 112488 B FI112488 B FI 112488B FI 962892 A FI962892 A FI 962892A FI 962892 A FI962892 A FI 962892A FI 112488 B FI112488 B FI 112488B
Authority
FI
Finland
Prior art keywords
group
pyridazine
pharmacologically acceptable
propenyl
fph
Prior art date
Application number
FI962892A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI962892A (fi
FI962892A0 (fi
Inventor
Tomio Kimura
Yoshimi Fujihara
Hiroshi Yasuda
Keiichi Tabata
Nobuhiko Shibakawa
Hiroshi Fujiwara
Etsuro Itoh
Keiji Matsunobu
Original Assignee
Sankyo Co
Ube Industries
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co, Ube Industries filed Critical Sankyo Co
Publication of FI962892A0 publication Critical patent/FI962892A0/fi
Publication of FI962892A publication Critical patent/FI962892A/fi
Application granted granted Critical
Publication of FI112488B publication Critical patent/FI112488B/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
FI962892A 1994-01-19 1996-07-18 Aryylialkyyli- tai heteroaryylialkyylisubstituoidut pyrrolopyridatsiinijohdannaiset FI112488B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP398894 1994-01-19
JP398894 1994-01-19
PCT/JP1995/000038 WO1995019980A1 (fr) 1994-01-19 1995-01-18 Derive de pyrrolopyridazine
JP9500038 1995-01-18

Publications (3)

Publication Number Publication Date
FI962892A0 FI962892A0 (fi) 1996-07-18
FI962892A FI962892A (fi) 1996-09-16
FI112488B true FI112488B (fi) 2003-12-15

Family

ID=11572411

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962892A FI112488B (fi) 1994-01-19 1996-07-18 Aryylialkyyli- tai heteroaryylialkyylisubstituoidut pyrrolopyridatsiinijohdannaiset

Country Status (19)

Country Link
US (1) US6063782A (da)
EP (1) EP0742218B1 (da)
KR (1) KR100361199B1 (da)
CN (1) CN1044811C (da)
AT (1) ATE229020T1 (da)
AU (1) AU680998B2 (da)
CZ (1) CZ283216B6 (da)
DE (1) DE69529056T2 (da)
DK (1) DK0742218T3 (da)
ES (1) ES2185693T3 (da)
FI (1) FI112488B (da)
HK (1) HK1015609A1 (da)
HU (1) HU225920B1 (da)
MX (1) MX9602850A (da)
NO (1) NO307300B1 (da)
NZ (1) NZ278675A (da)
PT (1) PT742218E (da)
RU (1) RU2146257C1 (da)
WO (1) WO1995019980A1 (da)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6316429B1 (en) * 1997-05-07 2001-11-13 Sugen, Inc. Bicyclic protein kinase inhibitors
SE9704404D0 (sv) 1997-11-28 1997-11-28 Astra Ab New compounds
DE19836698A1 (de) * 1998-08-13 2000-02-17 Bayer Ag Verfahren zur Herstellung von fluorierten Benzylalkoholen und -aldehyden
TWI287014B (en) * 1999-06-15 2007-09-21 Sankyo Co Optically active pyrrolopyridazine compound
BR0108251A (pt) * 2000-02-10 2003-03-25 Sankyo Co Derivado de pirrolopiridazina ou um sal deste farmaceuticamente aceitável, composição farmacêutica, agente contendo um derivado de pirrolopiridazina ou um sal deste farmaceuticamente aceitável, e, uso de um derivado de pirrolopiridazina ou um sal deste farmaceuticamente aceitável
FR2849025B1 (fr) * 2002-12-20 2005-10-14 Rhodia Chimie Sa Esters d'allyle substitue par un groupe difluoromethylene, leur procede de synthese et leur utilisation
JP2003119140A (ja) * 2001-08-08 2003-04-23 Sankyo Co Ltd ピロロピリダジン化合物を含有する医薬
CA2461040C (en) * 2001-09-27 2016-04-05 Monsanto Technology, Llc Fungicidal compositions and their applications in agriculture
TW200418479A (en) * 2002-09-25 2004-10-01 Sankyo Co Pharmaceutical compositions for the treatment or prevention of visceral pains
TW200420293A (en) * 2002-09-25 2004-10-16 Sankyo Co Pharmaceutical compositions for the reduction of gastric acid concentration in blood
EP1611901B1 (en) * 2003-03-13 2013-07-10 Eisai R&D Management Co., Ltd. Preventive or remedy for teeth grinding
RU2397170C2 (ru) * 2004-09-03 2010-08-20 Юхан Корпорейшн ПРОИЗВОДНЫЕ ПИРРОЛО[3,2-b]ПИРИДИНА И СПОСОБЫ ИХ ПОЛУЧЕНИЯ
KR100946220B1 (ko) * 2004-09-03 2010-03-08 주식회사유한양행 피롤로[3,2-ｃ]피리딘 유도체 및 그의 제조방법
CA2578880C (en) * 2004-09-03 2013-01-29 Yuhan Corporation Pyrrolo[3,2-c]pyridine derivatives and processes for the preparation thereof
KR101137168B1 (ko) * 2005-03-09 2012-04-19 주식회사유한양행 피롤로［２,３-ｄ］피리다진 유도체 및 그의 제조방법
KR20080094921A (ko) * 2006-01-16 2008-10-27 우베 고산 가부시키가이샤 피롤로피리다지논 화합물
CN101003537A (zh) * 2006-01-17 2007-07-25 上海恒瑞医药有限公司 吡咯并哒嗪类衍生物及其制备方法和用途
CA2787785C (en) 2010-01-28 2018-03-06 President And Fellows Of Harvard College Compositions and methods for enhancing proteasome activity
AU2012253402A1 (en) * 2011-05-12 2013-05-02 Proteostasis Therapeutics, Inc. Proteostasis regulators
WO2014116228A1 (en) 2013-01-25 2014-07-31 President And Fellows Of Harvard College Usp14 inhibitors for treating or preventing viral infections
WO2015073528A1 (en) 2013-11-12 2015-05-21 Proteostasis Therapeutics, Inc. Proteasome activity enhancing compounds
MX2017009164A (es) * 2015-01-13 2018-03-06 Vivreon Biosciences Llc Moduladores de canales de ca2+ activados de liberacion de ca2+ (crac) y usos farmaceuticos de los mismos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8901430D0 (en) * 1989-01-23 1989-03-15 Smithkline Beckman Intercredit Compounds
IL97931A0 (en) * 1990-04-27 1992-06-21 Byk Gulden Lomberg Chem Fab Pyridazine derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US5068332A (en) * 1990-10-12 1991-11-26 American Home Products Corporation Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors
AU8712191A (en) * 1990-10-15 1992-05-20 Byk Gulden Lomberg Chemische Fabrik Gmbh New diazines
DE59209687D1 (de) * 1991-10-25 1999-06-02 Byk Gulden Lomberg Chem Fab Pyrrolo-pyridazine mit magen- und darmschutzwirkungen

Also Published As

Publication number Publication date
AU680998B2 (en) 1997-08-14
PT742218E (pt) 2003-02-28
CN1143964A (zh) 1997-02-26
CZ208496A3 (en) 1996-12-11
HU9601967D0 (en) 1996-09-30
AU1465795A (en) 1995-08-08
EP0742218B1 (en) 2002-12-04
EP0742218A1 (en) 1996-11-13
HK1015609A1 (en) 1999-10-15
FI962892A (fi) 1996-09-16
FI962892A0 (fi) 1996-07-18
NZ278675A (en) 1997-07-27
CZ283216B6 (cs) 1998-02-18
NO307300B1 (no) 2000-03-13
DE69529056D1 (de) 2003-01-16
NO962998L (no) 1996-09-17
WO1995019980A1 (fr) 1995-07-27
RU2146257C1 (ru) 2000-03-10
US6063782A (en) 2000-05-16
DE69529056T2 (de) 2003-11-13
MX9602850A (es) 1997-06-28
DK0742218T3 (da) 2003-01-13
ES2185693T3 (es) 2003-05-01
HU225920B1 (en) 2008-01-28
EP0742218A4 (en) 1997-07-09
CN1044811C (zh) 1999-08-25
ATE229020T1 (de) 2002-12-15
NO962998D0 (no) 1996-07-18
KR100361199B1 (ko) 2003-04-16
HUT77998A (hu) 1999-04-28

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