HK1009751A1 - Antifungal agent compound therefor process for producing the same - Google Patents

Antifungal agent compound therefor process for producing the same

Info

Publication number
HK1009751A1
HK1009751A1 HK98110741A HK98110741A HK1009751A1 HK 1009751 A1 HK1009751 A1 HK 1009751A1 HK 98110741 A HK98110741 A HK 98110741A HK 98110741 A HK98110741 A HK 98110741A HK 1009751 A1 HK1009751 A1 HK 1009751A1
Authority
HK
Hong Kong
Prior art keywords
producing
same
antifungal agent
agent compound
compound therefor
Prior art date
Application number
HK98110741A
Other languages
English (en)
Inventor
Hiroki Kodama
Yoshimi Niwano
Kazuo Kanai
Masanori Yoshida
Original Assignee
Nihon Nohyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Nohyaku Co Ltd filed Critical Nihon Nohyaku Co Ltd
Publication of HK1009751A1 publication Critical patent/HK1009751A1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
HK98110741A 1995-07-08 1998-09-18 Antifungal agent compound therefor process for producing the same HK1009751A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP19617495 1995-07-08
PCT/JP1996/001872 WO1997002821A2 (fr) 1995-07-08 1996-07-05 Agent antifongique, son compose, son procede de production

Publications (1)

Publication Number Publication Date
HK1009751A1 true HK1009751A1 (en) 1999-06-11

Family

ID=16353435

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98110741A HK1009751A1 (en) 1995-07-08 1998-09-18 Antifungal agent compound therefor process for producing the same

Country Status (22)

Country Link
US (1) US5900488A (fr)
EP (1) EP0839035B1 (fr)
KR (1) KR100386491B1 (fr)
CN (1) CN1091596C (fr)
AT (1) AT407832B (fr)
CA (1) CA2226214C (fr)
CH (1) CH692045A5 (fr)
DE (1) DE19681478B4 (fr)
DK (1) DK176599B1 (fr)
ES (1) ES2137888B1 (fr)
FI (1) FI119357B (fr)
GB (1) GB2317615B (fr)
HK (1) HK1009751A1 (fr)
IL (1) IL122618A (fr)
IN (1) IN185384B (fr)
LU (1) LU90190B1 (fr)
NO (1) NO980055L (fr)
NZ (1) NZ311796A (fr)
SE (1) SE9800016D0 (fr)
TW (1) TW450969B (fr)
WO (1) WO1997002821A2 (fr)
ZA (1) ZA965745B (fr)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127397A (en) * 1996-12-10 2000-10-03 Nihon Nohyaku Co., Ltd. Optically active (R)-(E)-(4-substituted-phenyl-1,3-dithiolan-2-ylidene)-1-imidazolylaceto nitrile derivative, antifungal composition comprising the same, and method for producing the same
AU2003242235A1 (en) * 2002-06-18 2003-12-31 Pola Chemical Industries Inc. Antifungal medicinal composition
US8039452B2 (en) 2002-06-18 2011-10-18 Pola Pharma Inc. Antifungal medicinal compositions
EP2025337B1 (fr) * 2006-03-08 2014-09-10 Nihon Nohyaku Co., Ltd. Composition pharmaceutique à usage externe
CA2645070C (fr) 2006-03-08 2014-02-04 Nihon Nohyaku Co., Ltd. Composition pharmaceutique pour usage externe
RU2415669C2 (ru) 2006-03-08 2011-04-10 Нихон Нохияку Ко., Лтд. Фармацевтическая композиция для наружного применения
ES2588188T3 (es) * 2007-08-27 2016-10-31 Nihon Nohyaku Co., Ltd. Agente para la dermatitis fúngica
JP5453093B2 (ja) 2007-09-05 2014-03-26 株式会社ポーラファルマ 抗真菌医薬組成物
CN101808637B (zh) * 2007-09-05 2013-07-24 宝丽制药股份有限公司 医药组合物
KR20100075476A (ko) 2007-09-05 2010-07-02 가부시키가이샤 폴라 파마 항진균 조성물
WO2010093992A1 (fr) * 2009-02-13 2010-08-19 Topica Pharmaceuticals, Inc Formulation antifongique
EP2416757A2 (fr) 2009-04-09 2012-02-15 Pola Pharma Inc. Composition pharmaceutique antimycotique
KR101409792B1 (ko) 2009-04-09 2014-06-19 니혼노야쿠가부시키가이샤 항진균성 약제학적 조성물
KR101754697B1 (ko) 2009-08-25 2017-07-06 가부시키가이샤 폴라 파마 항진균성 약제학적 조성물
WO2011155640A1 (fr) * 2010-06-11 2011-12-15 Pola Pharma Inc. Composition pharmaceutique antimycosique
CN103012385B (zh) * 2012-02-17 2015-07-08 山东威智医药工业有限公司 卢立康唑的晶型及其制备方法
JP5460797B1 (ja) 2012-09-14 2014-04-02 株式会社ポーラファルマ アミド誘導体及び安定性指標としてのその使用
WO2014042231A1 (fr) * 2012-09-14 2014-03-20 Pola Pharma Inc. Cristal et préparation pharmaceutique le contenant
CN104619704B (zh) * 2012-09-14 2017-12-05 宝丽制药股份有限公司 表面自由能用于分化评价晶体的用途，基于表面自由能作为指标评价的晶体，以及通过包含所述晶体制备的药物组合物
US9199977B2 (en) * 2012-09-14 2015-12-01 Pola Pharma Inc. Crystal having crystal habits and pharmaceutical composition obtained by processing the crystal
US20150366845A1 (en) * 2013-01-28 2015-12-24 Pola Pharma Inc., Pharmaceutical composition for diseases caused by pathogenic microorganisms such as aspergillus
US20150352078A1 (en) * 2013-01-28 2015-12-10 Pola Pharma Inc. Pharmaceutical composition for diseases caused by pathogenic microorganisms such as candida
JP5589110B1 (ja) 2013-03-08 2014-09-10 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP5680161B1 (ja) * 2013-09-06 2015-03-04 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP5587488B1 (ja) 2013-12-12 2014-09-10 株式会社ポーラファルマ ルリコナゾールを含有する製剤の評価方法及び指標物質
AR100180A1 (es) * 2014-04-25 2016-09-14 Syngenta Participations Ag Derivados de imidazol microbiocidas
US10703744B2 (en) 2014-12-12 2020-07-07 Glenmark Life Sciences Limited Process for preparation of luliconazole
WO2017108972A1 (fr) 2015-12-21 2017-06-29 Laboratorios Lesvi, S.L. Composés de r-(-)-(e)-[4-(2,4-dichlorophényl)-1,3-dithiolan-2-ylidène]-1-imidazolylacétonitrile-ha (luliconazole-ha) à titre d'antifongiques
CN106008166B (zh) * 2016-05-17 2018-09-25 上海福乐医药科技有限公司 一种手性2-氯-1-(2,4-二氯苯基)乙醇的工业化生产方法
US11185548B2 (en) 2016-12-23 2021-11-30 Helmholtz Zentrum Munchen—Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Inhibitors of cytochrome P450 family 7 subfamily B member 1 (CYP7B1) for use in treating diseases
TR201714882A2 (tr) 2017-10-03 2019-04-22 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Luli̇konazolün topi̇kal farmasöti̇k kompozi̇syonlari
US10898470B1 (en) 2019-08-13 2021-01-26 Sato Pharmaceutical Co., Ltd. Pharmaceutical composition containing antifungal agent as active ingredient
WO2023131969A1 (fr) * 2022-01-09 2023-07-13 Kimia Biosciences Limited Procédé amélioré pour la préparation de luliconazole

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE87920T1 (de) * 1985-10-09 1993-04-15 Nihon Nohyaku Co Ltd Keten-s,s,-acetalderivate, verfahren zu ihrer herstellung und methode zur heilung von mykose unter verwendung dieser derivate.
EP0218736B1 (fr) * 1985-10-10 1993-04-07 Nihon Nohyaku Co., Ltd. Dérivé de cétène-S,S-acétal, procédé pour sa préparation et méthode pour guérir la mycose utilisant ce dérivé
JP3030780B2 (ja) * 1988-12-29 2000-04-10 日本農薬株式会社 光学活性なケテンジチオアセタール誘導体及びその製造方法
JPH0386337A (ja) * 1989-08-28 1991-04-11 Maeda Seisakusho:Kk エクスパンディングチャックを用いた多重巻締め機および多重巻締め方法
CN1038247C (zh) * 1990-05-16 1998-05-06 云南省建筑材料科学研究设计院 一种新型磷石膏胶结料
JP3038519B2 (ja) * 1992-01-28 2000-05-08 日本農薬株式会社 創傷治癒促進剤

Also Published As

Publication number Publication date
CN1194582A (zh) 1998-09-30
GB9726766D0 (en) 1998-02-18
IN185384B (fr) 2001-01-13
SE9800016L (sv) 1998-01-07
KR100386491B1 (ko) 2003-08-21
DE19681478B4 (de) 2006-09-21
CN1091596C (zh) 2002-10-02
KR19990028772A (ko) 1999-04-15
CA2226214A1 (fr) 1997-01-30
DK1398A (da) 1998-01-07
GB2317615A (en) 1998-04-01
DE19681478T1 (de) 1998-07-02
EP0839035B1 (fr) 2002-10-02
FI980023A0 (fi) 1998-01-07
DK176599B1 (da) 2008-10-27
IL122618A0 (en) 1998-08-16
MX9710401A (es) 1998-07-31
NO980055L (no) 1998-03-06
GB2317615B (en) 1998-09-02
ES2137888B1 (es) 2001-01-01
NZ311796A (en) 1999-06-29
EP0839035A2 (fr) 1998-05-06
NO980055D0 (no) 1998-01-06
AU6319296A (en) 1997-02-10
FI980023A (fi) 1998-01-07
CH692045A5 (de) 2002-01-15
ZA965745B (en) 1997-01-27
WO1997002821A3 (fr) 1997-02-20
SE9800016D0 (sv) 1998-01-07
IL122618A (en) 2002-07-25
ATA906196A (de) 2000-11-15
US5900488A (en) 1999-05-04
WO1997002821A2 (fr) 1997-01-30
CA2226214C (fr) 2007-04-17
TW450969B (en) 2001-08-21
AT407832B (de) 2001-06-25
ES2137888A1 (es) 1999-12-16
LU90190B1 (de) 1998-03-02
FI119357B (fi) 2008-10-31
AU697571B2 (en) 1998-10-08

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Legal Events

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PF Patent in force
PE Patent expired

Effective date: 20160704