FI980023A - Sienilääke, siihen soveltuva yhdiste, menetelmä niiden valmistamiseksi ja menetelmä niiden käyttämiseksi - Google Patents

Sienilääke, siihen soveltuva yhdiste, menetelmä niiden valmistamiseksi ja menetelmä niiden käyttämiseksi Download PDF

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Publication number
FI980023A
FI980023A FI980023A FI980023A FI980023A FI 980023 A FI980023 A FI 980023A FI 980023 A FI980023 A FI 980023A FI 980023 A FI980023 A FI 980023A FI 980023 A FI980023 A FI 980023A
Authority
FI
Finland
Prior art keywords
antifungal
preparation
suitable compound
compound
Prior art date
Application number
FI980023A
Other languages
English (en)
Swedish (sv)
Other versions
FI980023A0 (fi
FI119357B (fi
Inventor
Hiroki Kodama
Yoshimi Niwano
Kazuo Kanai
Masanori Yoshida
Original Assignee
Nihon Nohyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Nohyaku Co Ltd filed Critical Nihon Nohyaku Co Ltd
Publication of FI980023A0 publication Critical patent/FI980023A0/fi
Publication of FI980023A publication Critical patent/FI980023A/fi
Application granted granted Critical
Publication of FI119357B publication Critical patent/FI119357B/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI980023A 1995-07-08 1998-01-07 Sienilääke, siihen soveltuva yhdiste ja menetelmä niiden valmistamiseksi FI119357B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP19617495 1995-07-08
JP19617495 1995-07-08
JP9601872 1996-07-05
PCT/JP1996/001872 WO1997002821A2 (en) 1995-07-08 1996-07-05 Antifungal agent, compound therefor, process for producing the same

Publications (3)

Publication Number Publication Date
FI980023A0 FI980023A0 (fi) 1998-01-07
FI980023A true FI980023A (fi) 1998-01-07
FI119357B FI119357B (fi) 2008-10-31

Family

ID=16353435

Family Applications (1)

Application Number Title Priority Date Filing Date
FI980023A FI119357B (fi) 1995-07-08 1998-01-07 Sienilääke, siihen soveltuva yhdiste ja menetelmä niiden valmistamiseksi

Country Status (22)

Country Link
US (1) US5900488A (fi)
EP (1) EP0839035B1 (fi)
KR (1) KR100386491B1 (fi)
CN (1) CN1091596C (fi)
AT (1) AT407832B (fi)
CA (1) CA2226214C (fi)
CH (1) CH692045A5 (fi)
DE (1) DE19681478B4 (fi)
DK (1) DK176599B1 (fi)
ES (1) ES2137888B1 (fi)
FI (1) FI119357B (fi)
GB (1) GB2317615B (fi)
HK (1) HK1009751A1 (fi)
IL (1) IL122618A (fi)
IN (1) IN185384B (fi)
LU (1) LU90190B1 (fi)
NO (1) NO980055L (fi)
NZ (1) NZ311796A (fi)
SE (1) SE9800016L (fi)
TW (1) TW450969B (fi)
WO (1) WO1997002821A2 (fi)
ZA (1) ZA965745B (fi)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6127397A (en) * 1996-12-10 2000-10-03 Nihon Nohyaku Co., Ltd. Optically active (R)-(E)-(4-substituted-phenyl-1,3-dithiolan-2-ylidene)-1-imidazolylaceto nitrile derivative, antifungal composition comprising the same, and method for producing the same
EP1537868B1 (en) * 2002-06-18 2011-08-24 Pola Pharma Inc. Antifungal medicinal compositions
WO2003105903A1 (ja) * 2002-06-18 2003-12-24 ポーラ化成工業株式会社 抗真菌医薬組成物
WO2007102243A1 (ja) * 2006-03-08 2007-09-13 Nihon Nohyaku Co., Ltd. 外用の医薬組成物
CA2645070C (en) 2006-03-08 2014-02-04 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
EP2025337B1 (en) 2006-03-08 2014-09-10 Nihon Nohyaku Co., Ltd. Pharmaceutical composition for external use
CN101820877B (zh) * 2007-08-27 2013-09-11 日本农药株式会社 用于真菌性皮炎的药剂
WO2009031642A1 (ja) 2007-09-05 2009-03-12 Pola Pharma Inc. 医薬組成物
JP5345937B2 (ja) 2007-09-05 2013-11-20 株式会社ポーラファルマ 抗真菌組成物
EP2191828B1 (en) 2007-09-05 2016-08-10 Pola Pharma Inc. Antifungal pharmaceutical composition
EP2395839B1 (en) * 2009-02-13 2014-05-07 Topica Pharmaceuticals, Inc Anti-fungal formulation
US10130610B2 (en) 2009-04-09 2018-11-20 Pola Pharma Inc. Antimycotic pharmaceutical composition
JP5688406B2 (ja) 2009-04-09 2015-03-25 株式会社ポーラファルマ 抗真菌医薬組成物
JP5635075B2 (ja) * 2009-08-25 2014-12-03 株式会社ポーラファルマ 抗真菌医薬組成物
WO2011155640A1 (en) * 2010-06-11 2011-12-15 Pola Pharma Inc. Antimycotic pharmaceutical composition
CN103012385B (zh) * 2012-02-17 2015-07-08 山东威智医药工业有限公司 卢立康唑的晶型及其制备方法
US9199977B2 (en) * 2012-09-14 2015-12-01 Pola Pharma Inc. Crystal having crystal habits and pharmaceutical composition obtained by processing the crystal
IN2015DN02929A (fi) * 2012-09-14 2015-09-18 Pola Pharma Inc
JP5460797B1 (ja) 2012-09-14 2014-04-02 株式会社ポーラファルマ アミド誘導体及び安定性指標としてのその使用
CN104619704B (zh) * 2012-09-14 2017-12-05 宝丽制药股份有限公司 表面自由能用于分化评价晶体的用途，基于表面自由能作为指标评价的晶体，以及通过包含所述晶体制备的药物组合物
WO2014115488A1 (en) * 2013-01-28 2014-07-31 Pola Pharma Inc. Pharmaceutical composition for diseases caused by pathogenic microorganisms such as candida
EP2948145A1 (en) * 2013-01-28 2015-12-02 Pola Pharma Inc. Pharmaceutical composition for diseases caused by pathogenic microorganisms such as aspergillus
JP5589110B1 (ja) 2013-03-08 2014-09-10 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP5680161B1 (ja) * 2013-09-06 2015-03-04 株式会社ポーラファルマ 晶癖を有する結晶及び該結晶を有効成分として含有する医薬組成物
JP5587488B1 (ja) 2013-12-12 2014-09-10 株式会社ポーラファルマ ルリコナゾールを含有する製剤の評価方法及び指標物質
WO2015162271A1 (en) * 2014-04-25 2015-10-29 Syngenta Participations Ag Microbiocidal imidazole derivatives
US10703744B2 (en) 2014-12-12 2020-07-07 Glenmark Life Sciences Limited Process for preparation of luliconazole
WO2017108972A1 (en) 2015-12-21 2017-06-29 Laboratorios Lesvi, S.L. Compounds of r-(-)-(e)-[4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-1 -imidazolylacetonitrile-ha (luliconazole-ha) as antifungals
CN106008166B (zh) * 2016-05-17 2018-09-25 上海福乐医药科技有限公司 一种手性2-氯-1-(2,4-二氯苯基)乙醇的工业化生产方法
US11185548B2 (en) 2016-12-23 2021-11-30 Helmholtz Zentrum Munchen—Deutsches Forschungszentrum Für Gesundheit Und Umwelt (Gmbh) Inhibitors of cytochrome P450 family 7 subfamily B member 1 (CYP7B1) for use in treating diseases
TR201714882A2 (tr) 2017-10-03 2019-04-22 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Luli̇konazolün topi̇kal farmasöti̇k kompozi̇syonlari
US10898470B1 (en) 2019-08-13 2021-01-26 Sato Pharmaceutical Co., Ltd. Pharmaceutical composition containing antifungal agent as active ingredient
WO2023131969A1 (en) * 2022-01-09 2023-07-13 Kimia Biosciences Limited Improved process for the preparation of luliconazole

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0218736B1 (en) * 1985-10-10 1993-04-07 Nihon Nohyaku Co., Ltd. A ketene s,s-acetal derivative, a process for manufacturing thereof and a method for curing mycosis by administering it
ATE87920T1 (de) * 1985-10-09 1993-04-15 Nihon Nohyaku Co Ltd Keten-s,s,-acetalderivate, verfahren zu ihrer herstellung und methode zur heilung von mykose unter verwendung dieser derivate.
JP3030780B2 (ja) * 1988-12-29 2000-04-10 日本農薬株式会社 光学活性なケテンジチオアセタール誘導体及びその製造方法
JPH0386337A (ja) * 1989-08-28 1991-04-11 Maeda Seisakusho:Kk エクスパンディングチャックを用いた多重巻締め機および多重巻締め方法
CN1038247C (zh) * 1990-05-16 1998-05-06 云南省建筑材料科学研究设计院 一种新型磷石膏胶结料
JP3038519B2 (ja) * 1992-01-28 2000-05-08 日本農薬株式会社 創傷治癒促進剤

Also Published As

Publication number Publication date
AU6319296A (en) 1997-02-10
HK1009751A1 (en) 1999-06-11
ES2137888A1 (es) 1999-12-16
DK1398A (da) 1998-01-07
NO980055L (no) 1998-03-06
DE19681478T1 (de) 1998-07-02
MX9710401A (es) 1998-07-31
GB2317615B (en) 1998-09-02
AU697571B2 (en) 1998-10-08
CN1091596C (zh) 2002-10-02
EP0839035B1 (en) 2002-10-02
AT407832B (de) 2001-06-25
TW450969B (en) 2001-08-21
CA2226214A1 (en) 1997-01-30
NO980055D0 (no) 1998-01-06
CN1194582A (zh) 1998-09-30
SE9800016D0 (sv) 1998-01-07
FI980023A0 (fi) 1998-01-07
WO1997002821A3 (en) 1997-02-20
LU90190B1 (de) 1998-03-02
FI119357B (fi) 2008-10-31
IL122618A0 (en) 1998-08-16
EP0839035A2 (en) 1998-05-06
ZA965745B (en) 1997-01-27
CH692045A5 (de) 2002-01-15
GB2317615A (en) 1998-04-01
US5900488A (en) 1999-05-04
CA2226214C (en) 2007-04-17
GB9726766D0 (en) 1998-02-18
IN185384B (fi) 2001-01-13
IL122618A (en) 2002-07-25
WO1997002821A2 (en) 1997-01-30
KR19990028772A (ko) 1999-04-15
SE9800016L (sv) 1998-01-07
ES2137888B1 (es) 2001-01-01
DE19681478B4 (de) 2006-09-21
DK176599B1 (da) 2008-10-27
KR100386491B1 (ko) 2003-08-21
ATA906196A (de) 2000-11-15
NZ311796A (en) 1999-06-29

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