HK1008545A1 - Novel nitrile hydratase - Google Patents

Novel nitrile hydratase

Info

Publication number
HK1008545A1
HK1008545A1 HK98108862A HK98108862A HK1008545A1 HK 1008545 A1 HK1008545 A1 HK 1008545A1 HK 98108862 A HK98108862 A HK 98108862A HK 98108862 A HK98108862 A HK 98108862A HK 1008545 A1 HK1008545 A1 HK 1008545A1
Authority
HK
Hong Kong
Prior art keywords
nitrile hydratase
novel nitrile
novel
hydratase
nitrile
Prior art date
Application number
HK98108862A
Other languages
English (en)
Inventor
Kiyoshi Ito
Toshifumi Yamaki
Teruo Arii
Miyuki Tsuruoka
Takeshi Nakamura
Original Assignee
Mitsui Chemicals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Chemicals Inc filed Critical Mitsui Chemicals Inc
Publication of HK1008545A1 publication Critical patent/HK1008545A1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/78Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HK98108862A 1996-02-14 1998-07-03 Novel nitrile hydratase HK1008545A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2700496 1996-02-14

Publications (1)

Publication Number Publication Date
HK1008545A1 true HK1008545A1 (en) 1999-05-14

Family

ID=12208988

Family Applications (4)

Application Number Title Priority Date Filing Date
HK98108862A HK1008545A1 (en) 1996-02-14 1998-07-03 Novel nitrile hydratase
HK04108326A HK1065563A1 (en) 1996-02-14 2004-10-25 Novel nitrile hydratase
HK04108327A HK1065564A1 (en) 1996-02-14 2004-10-25 Novel nitrile hydratase
HK04108328A HK1065567A1 (en) 1996-02-14 2004-10-25 A method for producing an amide from the nitrile cA method for producing an amide from the nitrile compound ompound

Family Applications After (3)

Application Number Title Priority Date Filing Date
HK04108326A HK1065563A1 (en) 1996-02-14 2004-10-25 Novel nitrile hydratase
HK04108327A HK1065564A1 (en) 1996-02-14 2004-10-25 Novel nitrile hydratase
HK04108328A HK1065567A1 (en) 1996-02-14 2004-10-25 A method for producing an amide from the nitrile cA method for producing an amide from the nitrile compound ompound

Country Status (6)

Country Link
US (2) US5807730A (de)
EP (1) EP0790310B1 (de)
KR (1) KR100234489B1 (de)
CN (4) CN1240833C (de)
DE (1) DE69739026D1 (de)
HK (4) HK1008545A1 (de)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030104973A1 (en) * 1997-08-21 2003-06-05 Quark Biotech, Inc. Hypoxia-regulated genes
JP3408737B2 (ja) 1998-03-16 2003-05-19 三井化学株式会社 ニトリルヒドラターゼの活性化に関与するタンパク質及びそれをコードする遺伝子
DE60133691T2 (de) * 2000-01-17 2009-05-28 Mitsui Chemicals, Inc. Verfahren zur reinigung von amiden
DE60129547T2 (de) * 2000-03-21 2008-04-17 Mitsubishi Rayon Co., Ltd. Verfahren zur kultivierung von mikroorganismen
TWI296652B (en) 2000-03-29 2008-05-11 Mitsui Chemicals Inc Production process of amide compound
US7749739B2 (en) 2000-12-20 2010-07-06 Dia-Nitrix Co., Ltd. Process for producing amide compound using microbial catalyst
JP4668444B2 (ja) * 2001-03-27 2011-04-13 ダイヤニトリックス株式会社 アクリル酸水溶液で洗浄した微生物触媒によるアクリルアミドの製造方法。
JP2004194588A (ja) * 2002-12-19 2004-07-15 Mitsui Chemicals Inc 新規なニトリルヒドラターゼ
DE102004013824A1 (de) 2004-03-20 2005-10-13 Degussa Ag Nitrilhydratasen aus Rhodococcus opacus
EP1991659B1 (de) 2006-01-30 2018-04-04 Georgia State University Research Foundation, Inc. Induktion und stabilisierung enzymatischer aktivität in mikroorganismen
JP5214249B2 (ja) 2006-11-09 2013-06-19 三菱レイヨン株式会社 ベタインの製造方法
US7943549B2 (en) * 2007-04-02 2011-05-17 Georgia State University Research Foundation, Inc. Biological-based catalyst to delay plant development processes
KR101598643B1 (ko) * 2008-03-14 2016-02-29 다이야니트릭스 가부시키가이샤 아크릴아마이드 수용액의 안정화 방법
US8871484B2 (en) * 2008-11-14 2014-10-28 Mitsui Chemicals, Inc. Nitrile hydratase variant
CN102010826B (zh) * 2009-07-24 2016-03-16 大野绿水株式会社 微生物菌体的保存方法及微生物菌体的混悬液
US20110039314A1 (en) * 2009-08-14 2011-02-17 Loyola University Of Chicago Composition for Catalytic Amide Production and Uses Thereof
WO2012164933A1 (ja) 2011-05-31 2012-12-06 ダイヤニトリックス株式会社 改良型ニトリルヒドラターゼ
WO2012169203A1 (ja) 2011-06-07 2012-12-13 ダイヤニトリックス株式会社 改良型ニトリルヒドラターゼ
CN102517271B (zh) * 2011-12-13 2013-04-03 清华大学 一种突变腈水合酶
CN104145017B (zh) 2012-02-28 2017-03-15 三菱丽阳株式会社 酶的保存方法
MX361278B (es) 2013-03-14 2018-12-03 Univ Georgia State Res Found Inhibición o reducción del crecimiento de hongos.
MX360847B (es) 2013-03-14 2018-11-20 Univ Georgia State Res Found Prevencion o retardo de respuesta al daño por enfriamiento en plantas.
CN116536293A (zh) 2014-06-06 2023-08-04 三菱化学株式会社 改良型腈水合酶
CA2951900A1 (en) 2014-06-10 2015-12-17 Georgia State University And Research Foundation, Inc. Inhibiting or reducing fungal infections
KR102324118B1 (ko) 2016-12-28 2021-11-08 미쓰이 가가쿠 가부시키가이샤 변이형 나이트릴 히드라타아제, 그 변이형 나이트릴 히드라타아제를 코드하는 핵산, 그 핵산을 포함하는 발현 벡터 및 형질전환체, 그 변이형 나이트릴 히드라타아제의 제조 방법, 및 아마이드 화합물의 제조 방법
CN109652474A (zh) * 2018-12-26 2019-04-19 安徽巨成精细化工有限公司 生物催化丙烯腈水合反应的方法、产腈菌株的灭活方法
CN112626056B (zh) * 2020-12-30 2022-05-24 浙江工业大学 一种腈水合活性专一性提高的腈水解酶突变体及其应用
CN114277022B (zh) * 2021-12-03 2023-08-08 江南大学 一种高活性和高热稳定性的腈水合酶突变体

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2294999A1 (fr) 1974-12-18 1976-07-16 Anvar Procede de preparation d'amides par hydrolyse biologique
JPS54129190A (en) 1978-03-29 1979-10-06 Nitto Chem Ind Co Ltd Microbial preparation of acrylamide or methacrylamide
JPS5617918A (en) * 1979-07-23 1981-02-20 Chisso Corp Manufacture of dichlorosilane
JPS5648889A (en) 1979-09-28 1981-05-02 Nitto Chem Ind Co Ltd Preparation of acrylamide or methacrylamide by fermentation
JPS5937951B2 (ja) 1981-11-18 1984-09-12 秀明 山田 アミドの生物学的製造法
JPS5937951A (ja) * 1982-08-26 1984-03-01 井上工業株式会社 浴用気泡発生装置及びその製造方法
JPS61162193A (ja) 1985-01-08 1986-07-22 Nitto Chem Ind Co Ltd 微生物によるアミド類の製造法
DE3526050C2 (de) * 1985-07-20 1994-11-17 Krupp Ag Hoesch Krupp Verfahren zum Betreiben eines Extruders
JPS6231914A (ja) * 1985-08-05 1987-02-10 富士電機株式会社 接触子装置
DD274631A5 (de) 1987-09-18 1989-12-27 Kk Verfahren zur biologischen herstellung von amiden
JP2840253B2 (ja) * 1988-07-06 1998-12-24 輝彦 別府 ニトリルヒドラターゼ活性を有するポリペプチドをコードする遺伝子dna、これを含有する形質転換体によるニトリル類からアミド類の製造法
JPH074238B2 (ja) * 1990-04-24 1995-01-25 株式会社資生堂 ペプチドc末端アミド化酵素の製造方法
JP2907479B2 (ja) * 1990-02-28 1999-06-21 輝彦 別府 ニトリルヒドラターゼ活性を有するポリペプチドをコードする遺伝子dna、これを含有する形質転換体及びアミド類の製造法
AU627648B2 (en) * 1990-02-28 1992-08-27 Teruhiko Beppu Dna fragment encoding a polypeptide having nitrile hydratase activity, a transformant containing the gene and a process for the production of amides using the transformant
DE4102858A1 (de) * 1990-03-08 1991-09-12 Heidelberger Druckmasch Ag Druckwerkszylinder fuer rotationsdruckmaschinen
AU3692593A (en) * 1992-04-28 1993-11-04 Mitsubishi Kasei Corporation Novel protein having nitrile hydratase activity and the gene encoding the same, and a method for producing amides from nitriles via a transformant containing the gene
JPH0625296A (ja) * 1992-04-28 1994-02-01 Mitsubishi Kasei Corp ニトリルヒドラターゼ活性を有する新規なタンパク質およびそれをコードする遺伝子ならびに該遺伝子を含有する形質転換体によるニトリル類からアミド類の製造方法
JPH0655148A (ja) * 1992-08-06 1994-03-01 Hitachi Ltd ガラス基板洗浄装置
JPH06303971A (ja) * 1993-04-16 1994-11-01 Mitsubishi Kasei Corp ニトリルヒドラターゼ活性を有する新規なタンパク質およびそれをコードする遺伝子ならびに該遺伝子を含有する形質転換体によるニトリル類からアミド類の製造方法

Also Published As

Publication number Publication date
EP0790310A3 (de) 1998-02-18
US5807730A (en) 1998-09-15
HK1065563A1 (en) 2005-02-25
CN1240833C (zh) 2006-02-08
CN1101470C (zh) 2003-02-12
CN1492042A (zh) 2004-04-28
HK1065564A1 (en) 2005-02-25
CN1260363C (zh) 2006-06-21
EP0790310A2 (de) 1997-08-20
DE69739026D1 (de) 2008-11-20
CN1243825C (zh) 2006-03-01
KR970062038A (ko) 1997-09-12
HK1065567A1 (en) 2005-02-25
CN1492043A (zh) 2004-04-28
CN1492048A (zh) 2004-04-28
KR100234489B1 (ko) 1999-12-15
CN1170041A (zh) 1998-01-14
US5910432A (en) 1999-06-08
EP0790310B1 (de) 2008-10-08

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20120213