HK1008433A1 - Methods and diagnostic kits for determining the toxicity of a compound utilizing bacterial stress promoters fused to reporter genes - Google Patents

Methods and diagnostic kits for determining the toxicity of a compound utilizing bacterial stress promoters fused to reporter genes

Info

Publication number
HK1008433A1
HK1008433A1 HK98109159A HK98109159A HK1008433A1 HK 1008433 A1 HK1008433 A1 HK 1008433A1 HK 98109159 A HK98109159 A HK 98109159A HK 98109159 A HK98109159 A HK 98109159A HK 1008433 A1 HK1008433 A1 HK 1008433A1
Authority
HK
Hong Kong
Prior art keywords
stress
methods
toxicity
diagnostic kits
compound
Prior art date
Application number
HK98109159A
Other languages
English (en)
Inventor
B Spencer Farr
Original Assignee
Harvard College
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Harvard College filed Critical Harvard College
Publication of HK1008433A1 publication Critical patent/HK1008433A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
HK98109159A 1992-07-06 1998-07-14 Methods and diagnostic kits for determining the toxicity of a compound utilizing bacterial stress promoters fused to reporter genes HK1008433A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91079392A 1992-07-06 1992-07-06
PCT/US1993/006537 WO1994001584A1 (fr) 1992-07-06 1993-07-06 Procedes et necessaires de diagnostic pour determiner la toxicite utilisant des promoteurs de stress bacteriens fusionnes a des genes rapporteurs

Publications (1)

Publication Number Publication Date
HK1008433A1 true HK1008433A1 (en) 1999-05-07

Family

ID=25429335

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98109159A HK1008433A1 (en) 1992-07-06 1998-07-14 Methods and diagnostic kits for determining the toxicity of a compound utilizing bacterial stress promoters fused to reporter genes

Country Status (15)

Country Link
US (2) US5589337A (fr)
EP (1) EP0651825B1 (fr)
JP (1) JP3456703B2 (fr)
KR (1) KR100300932B1 (fr)
AT (1) ATE162225T1 (fr)
AU (1) AU687353B2 (fr)
CA (1) CA2139667C (fr)
DE (1) DE69316368T2 (fr)
DK (1) DK0651825T3 (fr)
ES (1) ES2113546T3 (fr)
GR (1) GR3026639T3 (fr)
HK (1) HK1008433A1 (fr)
NO (1) NO319372B1 (fr)
SG (1) SG77101A1 (fr)
WO (1) WO1994001584A1 (fr)

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ATE439441T1 (de) * 2000-02-23 2009-08-15 Life Technologies Corp Veränderte, fluoreszierende proteine
US6696239B1 (en) 2000-04-20 2004-02-24 Biolog, Inc. Comparative phenotype analysis for assessment of biological active compounds such as antimicrobials
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US20030171876A1 (en) * 2002-03-05 2003-09-11 Victor Markowitz System and method for managing gene expression data
US6667153B1 (en) 2000-06-26 2003-12-23 Susan Margaret Thomas Composition and method for detecting mutagens
EP1409718A2 (fr) * 2000-07-21 2004-04-21 Phase-1 Molecular Toxicology Genes canins de toxicite
US20030119094A1 (en) * 2001-09-24 2003-06-26 Irm Llc Solubility reporter gene constructs
EP1364055A4 (fr) * 2000-11-21 2004-08-25 Irm Llc Constructions de genes rapporteurs de solubilite
WO2002059560A2 (fr) * 2001-01-23 2002-08-01 Gene Logic, Inc. Methode et systeme de prediction de l'activite biologique, y compris de la toxicologie et de la toxicite de substances
US7054758B2 (en) * 2001-01-30 2006-05-30 Sciona Limited Computer-assisted means for assessing lifestyle risk factors
US7405081B2 (en) * 2001-02-05 2008-07-29 Pan Shen Q Methods and kits for identifying scavengers of reactive oxygen species (ROS)
WO2002073504A1 (fr) * 2001-03-14 2002-09-19 Gene Logic, Inc. Systeme et procede d'extraction et d'utilisation de donnees d'expression genique provenant de multiples sources
US20020146698A1 (en) * 2001-04-05 2002-10-10 Genelink, Inc. Kits and methods for assessing oxidative stress
US7211383B2 (en) * 2001-04-05 2007-05-01 Genelink, Inc. Kits and methods for assessing skin health
US7251642B1 (en) 2001-08-06 2007-07-31 Gene Logic Inc. Analysis engine and work space manager for use with gene expression data
DE20116898U1 (de) * 2001-10-15 2002-01-17 Festo Ag & Co Mikroventil
KR20030040923A (ko) * 2001-11-17 2003-05-23 광주과학기술원 산화적 손상과 관련된 유해성 탐지를 위한 재조합발광박테리아 대장균ＤＨ5@/ｐＳｏｄａＬｕｘ（ＥＢＨＪ1）［ＫＣＴＣ10098ＢＰ］
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WO2005045426A2 (fr) * 2003-11-10 2005-05-19 Aic Profilage de l'expression genetique de composes dangereux et algorithme correspondant de groupage de base de donnees
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WO2006096063A1 (fr) * 2005-03-11 2006-09-14 Stichting Voor De Technische Wetenschappen Construction et methode pour cribler, selectionner et identifier des facteurs de stress
US7646450B2 (en) * 2005-12-29 2010-01-12 Lg Display Co., Ltd. Light emitting diode array, method of manufacturing the same, backlight assembly having the same, and LCD having the same
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WO2019160998A1 (fr) * 2018-02-13 2019-08-22 Twinstrand Biosciences, Inc. Méthodes et réactifs pour la détection et l'évaluation de la génotoxicité
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Also Published As

Publication number Publication date
NO950040L (no) 1995-03-06
CA2139667A1 (fr) 1994-01-20
US5589337A (en) 1996-12-31
JP3456703B2 (ja) 2003-10-14
DE69316368D1 (de) 1998-02-19
US5585232A (en) 1996-12-17
WO1994001584A1 (fr) 1994-01-20
KR100300932B1 (ko) 2001-10-22
GR3026639T3 (en) 1998-07-31
EP0651825A1 (fr) 1995-05-10
NO319372B1 (no) 2005-07-25
ES2113546T3 (es) 1998-05-01
JPH08501930A (ja) 1996-03-05
EP0651825B1 (fr) 1998-01-14
KR950702639A (ko) 1995-07-29
AU687353B2 (en) 1998-02-26
DE69316368T2 (de) 1998-06-25
CA2139667C (fr) 2005-03-29
NO950040D0 (no) 1995-01-05
ATE162225T1 (de) 1998-01-15
AU4588493A (en) 1994-01-31
SG77101A1 (en) 2000-12-19
DK0651825T3 (da) 1998-09-14

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20040706