HK1006568A1 - Medicament containing crystalline fumaric acid salts of 9,9-alkylen-3,7 diazabicyclononane compounds - Google Patents

Medicament containing crystalline fumaric acid salts of 9,9-alkylen-3,7 diazabicyclononane compounds Download PDF

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Publication number
HK1006568A1
HK1006568A1 HK98105562A HK98105562A HK1006568A1 HK 1006568 A1 HK1006568 A1 HK 1006568A1 HK 98105562 A HK98105562 A HK 98105562A HK 98105562 A HK98105562 A HK 98105562A HK 1006568 A1 HK1006568 A1 HK 1006568A1
Authority
HK
Hong Kong
Prior art keywords
fumaric acid
diazabicyclo
formula
nonane
base
Prior art date
Application number
HK98105562A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1006568B (en
Inventor
Schon Uwe
Heitmann Walter
Matzel Uwe
Original Assignee
Abbott Products Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Products Gmbh filed Critical Abbott Products Gmbh
Publication of HK1006568B publication Critical patent/HK1006568B/xx
Publication of HK1006568A1 publication Critical patent/HK1006568A1/xx

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13—Dicarboxylic acids
    • C07C57/15—Fumaric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
HK98105562A 1991-12-03 1998-06-17 Medicament containing crystalline fumaric acid salts of 9,9-alkylen-3,7 diazabicyclononane compounds HK1006568A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4139763 1991-12-03
DE4139763A DE4139763A1 (de) 1991-12-03 1991-12-03 Kristalline fumarsaure salze von 9,9-alkylen-3,7-diazabicyclononan-verbindungen und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
HK1006568B HK1006568B (en) 1999-03-05
HK1006568A1 true HK1006568A1 (en) 1999-03-05

Family

ID=6446125

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98105562A HK1006568A1 (en) 1991-12-03 1998-06-17 Medicament containing crystalline fumaric acid salts of 9,9-alkylen-3,7 diazabicyclononane compounds

Country Status (25)

Country Link
US (1) US5324732A (cs)
EP (1) EP0550383B1 (cs)
JP (1) JP3180848B2 (cs)
KR (1) KR100252389B1 (cs)
CN (1) CN1040758C (cs)
AT (1) ATE124411T1 (cs)
AU (1) AU652869B2 (cs)
CA (1) CA2084489C (cs)
CZ (1) CZ281930B6 (cs)
DE (2) DE4139763A1 (cs)
DK (1) DK0550383T3 (cs)
DZ (1) DZ1636A1 (cs)
ES (1) ES2073900T3 (cs)
FI (1) FI100053B (cs)
HK (1) HK1006568A1 (cs)
HU (3) HU213672B (cs)
IL (1) IL103819A (cs)
LT (1) LTIP230A (cs)
MX (1) MX9206988A (cs)
NO (1) NO300687B1 (cs)
NZ (1) NZ245227A (cs)
PH (1) PH31114A (cs)
SK (1) SK279519B6 (cs)
TW (1) TW274084B (cs)
ZA (1) ZA928863B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4421324A1 (de) * 1994-06-17 1995-12-21 Kali Chemie Pharma Gmbh Neue 3,7-Diazabicyclo [3,3,1] nonan-Verbindungen enthaltende Arzneimittel
WO2002026214A1 (en) * 2000-09-29 2002-04-04 Solvay Pharmaceuticals B.V. Ion-strength independent sustained release pharmaceutical formulation
TW200418468A (en) * 2002-11-18 2004-10-01 Solvay Pharm Gmbh Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events
US20050054667A1 (en) * 2003-07-21 2005-03-10 Solvay Pharmaceuticals Gmbh Method of treating or inhibiting anti-arrhythmic events in male human patients
CN1822833A (zh) * 2003-07-21 2006-08-23 索尔瓦药物有限公司 3,7－二氮杂双环[3,3,1]壬烷化合物在治疗和/或预防男性患者心律失常中的用途
WO2005030207A1 (en) * 2003-09-26 2005-04-07 Solvay Pharmaceuticals Gmbh Use of 3, 7-diazabicyclo (3.3.1) nonane compounds for the treatment of brugada syndrome

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2551283C3 (de) * 1975-11-14 1981-02-19 Hokuriku Pharmaceutical Co., Ltd., Katsuyama, Fukui (Japan) Monofumarsäuresalz von 3-Pyridylmethylnikotinat und Verfahren zu seiner Herstellung
DE2658558A1 (de) * 1976-12-23 1978-06-29 Bayer Ag Diazabicyclo(3,3,1)nonane, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
PT88381B (pt) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline
DE4019080A1 (de) * 1990-06-15 1991-12-19 Kali Chemie Pharma Gmbh Neue 3,7-diazabicycolo (3,3,1)nonan-verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
IL103819A (en) 1996-09-12
CZ332292A3 (en) 1993-08-11
CZ281930B6 (cs) 1997-04-16
NZ245227A (en) 1994-06-27
EP0550383A1 (de) 1993-07-07
TW274084B (cs) 1996-04-11
AU2981592A (en) 1993-06-10
LTIP230A (en) 1994-05-15
JPH05247040A (ja) 1993-09-24
HU210215A9 (en) 1995-02-28
DK0550383T3 (da) 1995-08-28
DE59202726D1 (de) 1995-08-03
HU9203698D0 (en) 1993-03-29
PH31114A (en) 1998-02-23
ES2073900T3 (es) 1995-08-16
NO300687B1 (no) 1997-07-07
AU652869B2 (en) 1994-09-08
CN1040758C (zh) 1998-11-18
NO924647L (no) 1993-06-04
DE4139763A1 (de) 1993-06-09
US5324732A (en) 1994-06-28
JP3180848B2 (ja) 2001-06-25
KR930012772A (ko) 1993-07-21
FI100053B (fi) 1997-09-15
MX9206988A (es) 1993-06-01
CA2084489C (en) 2002-10-08
ATE124411T1 (de) 1995-07-15
CA2084489A1 (en) 1993-06-04
SK332292A3 (en) 1998-12-02
KR100252389B1 (ko) 2000-05-01
HU213672B (en) 1997-09-29
CN1072931A (zh) 1993-06-09
FI925482A0 (fi) 1992-12-02
EP0550383B1 (de) 1995-06-28
ZA928863B (en) 1993-05-13
DZ1636A1 (fr) 2002-02-17
FI925482L (fi) 1993-06-04
IL103819A0 (en) 1993-04-04
NO924647D0 (no) 1992-12-02
HUT63417A (en) 1993-08-30
SK279519B6 (sk) 1998-12-02

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Effective date: 20121123