PH31114A - Crystalline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and pharmaceutical compositions containing them. - Google Patents

Crystalline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and pharmaceutical compositions containing them.

Info

Publication number
PH31114A
PH31114A PH45289A PH45289A PH31114A PH 31114 A PH31114 A PH 31114A PH 45289 A PH45289 A PH 45289A PH 45289 A PH45289 A PH 45289A PH 31114 A PH31114 A PH 31114A
Authority
PH
Philippines
Prior art keywords
alkylene
fumaric acid
acid salts
pharmaceutical compositions
compositions containing
Prior art date
Application number
PH45289A
Other languages
English (en)
Inventor
Schon Uwe
Matzel Uwe
Heitmann Walter
Original Assignee
Kali Chemie Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kali Chemie Pharma Gmbh filed Critical Kali Chemie Pharma Gmbh
Publication of PH31114A publication Critical patent/PH31114A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10Spiro-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10Antioedematous agents; Diuretics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/13Dicarboxylic acids
    • C07C57/15Fumaric acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
PH45289A 1991-12-03 1992-11-19 Crystalline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and pharmaceutical compositions containing them. PH31114A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4139763A DE4139763A1 (de) 1991-12-03 1991-12-03 Kristalline fumarsaure salze von 9,9-alkylen-3,7-diazabicyclononan-verbindungen und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
PH31114A true PH31114A (en) 1998-02-23

Family

ID=6446125

Family Applications (1)

Application Number Title Priority Date Filing Date
PH45289A PH31114A (en) 1991-12-03 1992-11-19 Crystalline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and pharmaceutical compositions containing them.

Country Status (25)

Country Link
US (1) US5324732A (cs)
EP (1) EP0550383B1 (cs)
JP (1) JP3180848B2 (cs)
KR (1) KR100252389B1 (cs)
CN (1) CN1040758C (cs)
AT (1) ATE124411T1 (cs)
AU (1) AU652869B2 (cs)
CA (1) CA2084489C (cs)
CZ (1) CZ281930B6 (cs)
DE (2) DE4139763A1 (cs)
DK (1) DK0550383T3 (cs)
DZ (1) DZ1636A1 (cs)
ES (1) ES2073900T3 (cs)
FI (1) FI100053B (cs)
HK (1) HK1006568A1 (cs)
HU (3) HU9203698D0 (cs)
IL (1) IL103819A (cs)
LT (1) LTIP230A (cs)
MX (1) MX9206988A (cs)
NO (1) NO300687B1 (cs)
NZ (1) NZ245227A (cs)
PH (1) PH31114A (cs)
SK (1) SK332292A3 (cs)
TW (1) TW274084B (cs)
ZA (1) ZA928863B (cs)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4421324A1 (de) * 1994-06-17 1995-12-21 Kali Chemie Pharma Gmbh Neue 3,7-Diazabicyclo [3,3,1] nonan-Verbindungen enthaltende Arzneimittel
MXPA03002769A (es) * 2000-09-29 2003-07-28 Solvay Pharm Bv Formulacion farmaceutica de liberacion sostenida e independiente de la densidad ionica.
TW200418468A (en) * 2002-11-18 2004-10-01 Solvay Pharm Gmbh Liquid pharmaceutical formulations containing 3,7-diazabicyclo[3,3,1]nonane compounds and method of treatments relating to anti-arrhytmic events
US20050054667A1 (en) * 2003-07-21 2005-03-10 Solvay Pharmaceuticals Gmbh Method of treating or inhibiting anti-arrhythmic events in male human patients
MXPA06000796A (es) * 2003-07-21 2006-04-07 Solvay Pharm Gmbh Uso de los compuestos 3,7-diazabiciclo [3,3,1]nonano para el tratamiento y/o profilaxis de eventos antiarritmicos en pacientes humanos varones.
WO2005030207A1 (en) * 2003-09-26 2005-04-07 Solvay Pharmaceuticals Gmbh Use of 3, 7-diazabicyclo (3.3.1) nonane compounds for the treatment of brugada syndrome

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2551283C3 (de) * 1975-11-14 1981-02-19 Hokuriku Pharmaceutical Co., Ltd., Katsuyama, Fukui (Japan) Monofumarsäuresalz von 3-Pyridylmethylnikotinat und Verfahren zu seiner Herstellung
DE2658558A1 (de) * 1976-12-23 1978-06-29 Bayer Ag Diazabicyclo(3,3,1)nonane, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE3234697A1 (de) * 1982-09-18 1984-03-22 Kali-Chemie Pharma Gmbh, 3000 Hannover Neue diazabicyclo-(3,3,1)-nonane
PT88381B (pt) * 1987-09-09 1995-07-06 Kali Chemie Pharma Gmbh Processo para a preparacao de novos compostos 3,7-diazabiciclo{3,3,1} nonano, e de composicoes farmaceuticas que contem estes compostos
US4971992A (en) * 1989-03-27 1990-11-20 Hoechst-Roussel Pharmaceuticals Inc. Carbonate derivatives of eseroline
DE4019080A1 (de) * 1990-06-15 1991-12-19 Kali Chemie Pharma Gmbh Neue 3,7-diazabicycolo (3,3,1)nonan-verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
EP0550383A1 (de) 1993-07-07
US5324732A (en) 1994-06-28
CA2084489A1 (en) 1993-06-04
CN1040758C (zh) 1998-11-18
CN1072931A (zh) 1993-06-09
DZ1636A1 (fr) 2002-02-17
CA2084489C (en) 2002-10-08
IL103819A0 (en) 1993-04-04
ATE124411T1 (de) 1995-07-15
IL103819A (en) 1996-09-12
HU210215A9 (en) 1995-02-28
HU213672B (en) 1997-09-29
KR930012772A (ko) 1993-07-21
CZ281930B6 (cs) 1997-04-16
NO924647D0 (no) 1992-12-02
FI100053B (fi) 1997-09-15
FI925482L (fi) 1993-06-04
DK0550383T3 (da) 1995-08-28
AU2981592A (en) 1993-06-10
JP3180848B2 (ja) 2001-06-25
HU9203698D0 (en) 1993-03-29
JPH05247040A (ja) 1993-09-24
SK279519B6 (sk) 1998-12-02
SK332292A3 (en) 1998-12-02
DE59202726D1 (de) 1995-08-03
MX9206988A (es) 1993-06-01
CZ332292A3 (en) 1993-08-11
NO924647L (no) 1993-06-04
HK1006568A1 (en) 1999-03-05
FI925482A0 (fi) 1992-12-02
NZ245227A (en) 1994-06-27
EP0550383B1 (de) 1995-06-28
NO300687B1 (no) 1997-07-07
LTIP230A (en) 1994-05-15
TW274084B (cs) 1996-04-11
KR100252389B1 (ko) 2000-05-01
DE4139763A1 (de) 1993-06-09
AU652869B2 (en) 1994-09-08
ES2073900T3 (es) 1995-08-16
ZA928863B (en) 1993-05-13
HUT63417A (en) 1993-08-30

Similar Documents

Publication Publication Date Title
IL103778A (en) Organic salts of N,N'-diacetyl cystine process for their preparation and pharmaceutical compositions containing them
ZA925128B (en) Pyrrolidine derivatives,their preparation and medicaments containing them
IL110089A (en) Sulphonylaminopyrimidines their preparation and pharmaceutical compositions containing them
EP0500143A3 (en) Pharmaceutical composition comprising an aminoglycoside phosphate
JPS57159772A (en) 3,4-dihydro-5h-2,3-benzodiazepine derivatives, acid addition salts, manufacture and medicinal composition containing them
IL101583A (en) Quinoxalines processes for their preparation and pharmaceutical compositions containing them
SG123192G (en) Pharmaceutical compositions containing calcium salts
PH31114A (en) Crystalline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and pharmaceutical compositions containing them.
EP0331092A3 (en) Alpha-amino-carboxylic-acid derivatives, their preparation and use
IL79933A0 (en) (+)-6-chloro-5,10-dihydro-5-((1-methyl-4-piperidinyl)-acetyl)-11h-dibenzo(b,e)(1,4)diazepin-11-one and its acid addition salts,their preparation and pharmaceutical compositions containing them
IL86479A (en) Substituted vinylcephalosporins, their preparation and pharmaceutical compositions containing them
GR3017280T3 (en) Aminoalkylchromones, process for their preparation and compositions containing them.
EP0468327A3 (en) Oral pharmaceutical compositions containing hirudin
EP0418990A3 (en) 13-bromo and 13,14-dibromo ergoline, their preparation and their use
NZ216111A (en) 4(z)-6-((2,4,5-cis -4-o-hydroxyphenyl-2-trifluoro-methyl-1,3-dioxan-5-yl) hexanoic acid, pharmaceutical salts and pharmaceutical compositions thereof; ethers thereof
GR3030042T3 (en) Enantiomeric pure cis-2-oxa-5,8-diazabicyclo (4.3.0)nonanes and process for their preparation
IL103855A0 (en) 5,6-dihydro-dibenz(b,e)azepin-6,11-dione-11-oximes,their preparation and pharmaceutical compositions containing them
IL70007A0 (en) Azepino(1,2-a)pyrimidine derivatives and acid addition salts thereof and pharmaceutical compositions containing same
IL72726A (en) Crystalline salts of(s)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters with(r,s)1-pivaloyloxyethanol,their preparation and pharmaceutical compositions containing them
HU207316B (en) Process for producing octahydro-indolo/2,3-a/quinolyzinepphenyl-sulfonamide derivatives, acid additional salts thereof and pharmaceutical compositions containing them
IL76579A0 (en) Octahydroindolo(2,3-a)quinoli-zin-1-yl-alkanecarboxylic acid amides and their acid addition salts,their preparation and pharmaceutical compositions containing them
IL60726A0 (en) A pyrimido(5,4-d)pyrimidine compound and salts thereof andpharmaceutical compositions containing them
NZ220122A (en) Crystalline (5r,6s)-2-aminomethyl- -2-penem-3-carboxylic acid monohydrate, derivatives thereof, and pharmaceutical compositions
IL74064A (en) 1,7-disubstituted-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acid derivatives and antibacterial compositions containing them