HK1005705A1 - Use of rapamycin for the preparation of a medicament for the treatment of ocular inflammation - Google Patents

Use of rapamycin for the preparation of a medicament for the treatment of ocular inflammation Download PDF

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Publication number
HK1005705A1
HK1005705A1 HK98104905A HK98104905A HK1005705A1 HK 1005705 A1 HK1005705 A1 HK 1005705A1 HK 98104905 A HK98104905 A HK 98104905A HK 98104905 A HK98104905 A HK 98104905A HK 1005705 A1 HK1005705 A1 HK 1005705A1
Authority
HK
Hong Kong
Prior art keywords
rapamycin
aqueous humor
ocular inflammation
cyclosporin
dexamethasone
Prior art date
Application number
HK98104905A
Other languages
German (de)
English (en)
French (fr)
Chinese (zh)
Other versions
HK1005705B (en
Inventor
Shrikrishna Kulkarni Prasad
Original Assignee
University Of Louisville Research Foundation, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Louisville Research Foundation, Inc. filed Critical University Of Louisville Research Foundation, Inc.
Publication of HK1005705B publication Critical patent/HK1005705B/en
Publication of HK1005705A1 publication Critical patent/HK1005705A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Eye Examination Apparatus (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
HK98104905A 1991-07-25 1998-06-04 Use of rapamycin for the preparation of a medicament for the treatment of ocular inflammation HK1005705A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73560491A 1991-07-25 1991-07-25
US735604 2007-04-16

Publications (2)

Publication Number Publication Date
HK1005705B HK1005705B (en) 1999-01-22
HK1005705A1 true HK1005705A1 (en) 1999-01-22

Family

ID=24956475

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98104905A HK1005705A1 (en) 1991-07-25 1998-06-04 Use of rapamycin for the preparation of a medicament for the treatment of ocular inflammation

Country Status (20)

Country Link
US (1) US5387589A (cs)
EP (1) EP0532862B1 (cs)
JP (1) JP2568962B2 (cs)
KR (1) KR100216768B1 (cs)
AT (1) ATE133336T1 (cs)
AU (1) AU653415B2 (cs)
CA (1) CA2074641C (cs)
CZ (1) CZ285660B6 (cs)
DE (1) DE69207847T2 (cs)
DK (1) DK0532862T3 (cs)
ES (1) ES2083030T3 (cs)
HK (1) HK1005705A1 (cs)
HU (1) HU211218B (cs)
IE (1) IE922430A1 (cs)
IL (1) IL102414A (cs)
MX (1) MX9204381A (cs)
NZ (1) NZ243679A (cs)
RU (1) RU2048812C1 (cs)
SK (1) SK280511B6 (cs)
ZA (1) ZA924953B (cs)

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* Cited by examiner, † Cited by third party
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TW427904B (en) * 1995-12-07 2001-04-01 American Home Prod Neuroprotective agents
US5780462A (en) 1995-12-27 1998-07-14 American Home Products Corporation Water soluble rapamycin esters
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WO1997031020A1 (en) * 1996-02-22 1997-08-28 The General Hospital Corporation METHODS AND COMPOSITIONS FOR ENHANCING CELLULAR RESPONSE TO TGF-β LIGANDS
GB9606452D0 (en) * 1996-03-27 1996-06-05 Sandoz Ltd Organic compounds
JPH09278653A (ja) * 1996-04-05 1997-10-28 Santen Pharmaceut Co Ltd 網膜疾患治療剤
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Also Published As

Publication number Publication date
DE69207847D1 (de) 1996-03-07
IL102414A0 (en) 1993-01-14
CZ285660B6 (cs) 1999-10-13
CA2074641C (en) 1999-05-04
ZA924953B (en) 1993-04-28
ES2083030T3 (es) 1996-04-01
NZ243679A (en) 1997-06-24
AU653415B2 (en) 1994-09-29
EP0532862B1 (en) 1996-01-24
ATE133336T1 (de) 1996-02-15
SK280511B6 (sk) 2000-03-13
JP2568962B2 (ja) 1997-01-08
AU2035092A (en) 1993-01-28
IE922430A1 (en) 1993-01-27
HUT63763A (en) 1993-10-28
KR930001913A (ko) 1993-02-22
MX9204381A (es) 1993-02-01
RU2048812C1 (ru) 1995-11-27
US5387589A (en) 1995-02-07
DK0532862T3 (da) 1996-02-19
IL102414A (en) 1996-08-04
JPH05194212A (ja) 1993-08-03
DE69207847T2 (de) 1996-05-30
KR100216768B1 (ko) 1999-09-01
SK230792A3 (en) 1996-05-08
CZ230792A3 (en) 1993-02-17
HU9202448D0 (en) 1992-10-28
EP0532862A1 (en) 1993-03-24
CA2074641A1 (en) 1993-01-26
HU211218B (en) 1995-11-28

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