HK1003886A1 - Indole derivative - Google Patents

Indole derivative

Info

Publication number
HK1003886A1
HK1003886A1 HK98103026A HK98103026A HK1003886A1 HK 1003886 A1 HK1003886 A1 HK 1003886A1 HK 98103026 A HK98103026 A HK 98103026A HK 98103026 A HK98103026 A HK 98103026A HK 1003886 A1 HK1003886 A1 HK 1003886A1
Authority
HK
Hong Kong
Prior art keywords
lower alkoxy
alkoxy
alkoxycarbonyl
indole derivative
carboxy
Prior art date
Application number
HK98103026A
Other languages
English (en)
Inventor
Shiro Kato
Hiroshi Harada
Yoshimi Hirokawa
Naoyuki Yoshida
Hitoshi Kawashima
Original Assignee
Dainippon Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co filed Critical Dainippon Pharmaceutical Co
Publication of HK1003886A1 publication Critical patent/HK1003886A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
HK98103026A 1994-11-29 1998-04-09 Indole derivative HK1003886A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP06321402 1994-11-29
PCT/JP1995/002400 WO1996016938A1 (fr) 1994-11-29 1995-11-27 Derive d'indole

Publications (1)

Publication Number Publication Date
HK1003886A1 true HK1003886A1 (en) 1998-11-13

Family

ID=18132155

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98103026A HK1003886A1 (en) 1994-11-29 1998-04-09 Indole derivative

Country Status (29)

Country Link
US (1) US5817689A (es)
EP (1) EP0801059B1 (es)
JP (1) JP3100165B2 (es)
KR (1) KR100388747B1 (es)
CN (1) CN1070477C (es)
AT (1) ATE202559T1 (es)
AU (1) AU688165B2 (es)
BR (1) BR9509827A (es)
CA (1) CA2206307A1 (es)
CY (1) CY2247B1 (es)
CZ (1) CZ290871B6 (es)
DE (1) DE69521529T2 (es)
DK (1) DK0801059T3 (es)
ES (1) ES2159648T3 (es)
FI (1) FI972275A (es)
GR (1) GR3036148T3 (es)
HK (1) HK1003886A1 (es)
HU (1) HUT77308A (es)
IL (1) IL116178A (es)
NO (1) NO309648B1 (es)
NZ (1) NZ295749A (es)
PL (1) PL181963B1 (es)
PT (1) PT801059E (es)
RO (1) RO118426B1 (es)
RU (1) RU2137759C1 (es)
SK (1) SK281865B6 (es)
TW (1) TW349091B (es)
WO (1) WO1996016938A1 (es)
ZA (1) ZA9510130B (es)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PE20010580A1 (es) * 1999-09-03 2001-05-25 Takeda Chemical Industries Ltd Composicion farmaceutica para tratar la diabetes
CN1433403A (zh) * 1999-11-30 2003-07-30 大日本制药株式会社 固体制剂
US6458824B1 (en) * 1999-11-30 2002-10-01 Dainippon Pharmaceutical Co., Ltd. Solid preparation
JP2004331500A (ja) * 2001-02-16 2004-11-25 Dainippon Pharmaceut Co Ltd 血中濃度制御製剤
EP2335700A1 (en) * 2001-07-25 2011-06-22 Boehringer Ingelheim (Canada) Ltd. Hepatitis C virus polymerase inhibitors with a heterobicylic structure
US20040018959A1 (en) * 2002-05-02 2004-01-29 Randall S. Hickle System and methods of lipid removal from the body
KR20050010512A (ko) * 2002-06-12 2005-01-27 스미또모 세이야꾸 가부시키가이샤 인돌, 인다졸 및 벤즈아졸류
PL377847A1 (pl) * 2003-01-14 2006-02-20 Arena Pharmaceuticals Inc. 1,2,3-Tripodstawione pochodne arylowe i heteroarylowe jako modulatory metabolizmu oraz profilaktyka i leczenie związanych z nim zaburzeń takich jak cukrzyca i hiperglikemia
EP1927594A1 (en) * 2003-01-14 2008-06-04 Arena Pharmaceuticals, Inc. 1,2,3-Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
US7098231B2 (en) 2003-01-22 2006-08-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
US7223785B2 (en) 2003-01-22 2007-05-29 Boehringer Ingelheim International Gmbh Viral polymerase inhibitors
WO2004089936A1 (ja) * 2003-04-10 2004-10-21 Dainippon Pharmaceutical Co., Ltd. ヘテロアリールスルホン酸アニリド誘導体及びそれを含有する医薬組成物
AR045047A1 (es) 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
ES2431314T3 (es) * 2004-02-20 2013-11-26 Boehringer Ingelheim International Gmbh Inhibidores de polimerasa vírica
MY148521A (en) 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
DOP2006000010A (es) 2005-01-10 2006-07-31 Arena Pharm Inc Procedimiento para preparar eteres aromáticos
EP1915378A4 (en) 2005-08-12 2009-07-22 Boehringer Ingelheim Int VIRUS POLYMERASE INHIBITORS
BR112013008100A2 (pt) 2010-09-22 2016-08-09 Arena Pharm Inc "moduladores do receptor de gpr19 e o tratamento de distúrbios relacionados a eles."
ES2394349B1 (es) 2012-08-29 2013-11-04 Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar
WO2015199097A1 (ja) * 2014-06-24 2015-12-30 花王株式会社 Ｕｃｐ－１発現促進剤
JP6660668B2 (ja) * 2014-06-24 2020-03-11 花王株式会社 Ｕｃｐ−１発現促進剤
US10758519B2 (en) 2014-06-24 2020-09-01 Kao Corporation UCP-1 expression promoter
AU2016205361C1 (en) 2015-01-06 2021-04-08 Arena Pharmaceuticals, Inc. Methods of treating conditions related to the S1P1 receptor
SI3310760T1 (sl) 2015-06-22 2023-02-28 Arena Pharmaceuticals, Inc. Kristalinična L-argininska sol (R)-2-(7-(4-ciklopentil-3-(trifluorometil)benziloksi)-1,2,3,4- tetrahidrociklo-penta(b)indol-3-il)ocetne kisline za uporabo pri motnjah, povezanih z receptorjem S1P1

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB861428A (en) * 1958-07-14 1961-02-22 Searle & Co Improvements in or relating to indole derivatives
US4055658A (en) * 1976-05-17 1977-10-25 Mead Johnson & Company Cyanomethylphenethanolamines
DE3061334D1 (en) * 1979-06-16 1983-01-20 Beecham Group Plc Ethanamine derivatives, their preparation and use in pharmaceutical compositions
FR2541999B1 (fr) * 1983-03-04 1986-09-19 Bristol Myers Co Phenethanolamines et leurs utilisations
JPH06345731A (ja) * 1992-04-28 1994-12-20 Dainippon Pharmaceut Co Ltd ２−〔２−（インドール−３−イル）エチルアミノ〕−１−フェニルエタノール誘導体
JPH0634531A (ja) * 1992-07-14 1994-02-08 Yokogawa Electric Corp 赤外線水分計

Also Published As

Publication number Publication date
CA2206307A1 (en) 1996-06-06
HUT77308A (hu) 1998-03-30
PL181963B1 (pl) 2001-10-31
ZA9510130B (en) 1996-06-11
GR3036148T3 (en) 2001-09-28
BR9509827A (pt) 1997-09-30
ATE202559T1 (de) 2001-07-15
EP0801059A4 (en) 1998-01-21
KR100388747B1 (ko) 2004-03-30
PT801059E (pt) 2001-10-30
AU3936695A (en) 1996-06-19
EP0801059A1 (en) 1997-10-15
DE69521529T2 (de) 2001-10-11
IL116178A0 (en) 1996-01-31
CN1070477C (zh) 2001-09-05
JP3100165B2 (ja) 2000-10-16
NZ295749A (en) 1998-05-27
TW349091B (en) 1999-01-01
RO118426B1 (ro) 2003-05-30
DK0801059T3 (da) 2001-09-24
ES2159648T3 (es) 2001-10-16
RU2137759C1 (ru) 1999-09-20
NO309648B1 (no) 2001-03-05
CN1174549A (zh) 1998-02-25
CZ165597A3 (en) 1997-11-12
NO972427L (no) 1997-07-28
SK281865B6 (sk) 2001-08-06
NO972427D0 (no) 1997-05-28
PL320461A1 (en) 1997-09-29
US5817689A (en) 1998-10-06
DE69521529D1 (de) 2001-08-02
FI972275A0 (fi) 1997-05-29
CZ290871B6 (cs) 2002-11-13
FI972275A (fi) 1997-05-29
MX9703858A (es) 1997-09-30
IL116178A (en) 2000-07-26
WO1996016938A1 (fr) 1996-06-06
AU688165B2 (en) 1998-03-05
EP0801059B1 (en) 2001-06-27
SK65697A3 (en) 1998-01-14
CY2247B1 (en) 2003-07-04

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Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20051127