HK1001089A1 - Nitroxyalkylamide derivative - Google Patents
Nitroxyalkylamide derivative Download PDFInfo
- Publication number
- HK1001089A1 HK1001089A1 HK98100098A HK98100098A HK1001089A1 HK 1001089 A1 HK1001089 A1 HK 1001089A1 HK 98100098 A HK98100098 A HK 98100098A HK 98100098 A HK98100098 A HK 98100098A HK 1001089 A1 HK1001089 A1 HK 1001089A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- group
- optionally substituted
- nitroxyethyl
- compound
- phenyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
- C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/48—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/12—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/70—Nitro radicals
- C07D307/71—Nitro radicals attached in position 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Animal Behavior & Ethology (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP291410/91 | 1991-11-07 | ||
| JP29141091 | 1991-11-07 | ||
| PCT/JP1992/001419 WO1993009085A1 (fr) | 1991-11-07 | 1992-11-02 | Derive de nitroxyalkylamide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HK1001089B HK1001089B (en) | 1998-05-22 |
| HK1001089A1 true HK1001089A1 (en) | 1998-05-22 |
Family
ID=17768533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK98100098A HK1001089A1 (en) | 1991-11-07 | 1992-11-02 | Nitroxyalkylamide derivative |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US5580893A (cs) |
| EP (1) | EP0641768B1 (cs) |
| JP (1) | JP3454531B2 (cs) |
| KR (1) | KR100230633B1 (cs) |
| AT (1) | ATE155774T1 (cs) |
| AU (1) | AU662939B2 (cs) |
| CA (1) | CA2123101C (cs) |
| CZ (1) | CZ281710B6 (cs) |
| DE (1) | DE69221167T2 (cs) |
| DK (1) | DK0641768T3 (cs) |
| ES (1) | ES2106199T3 (cs) |
| FI (1) | FI942070A0 (cs) |
| GR (1) | GR3025056T3 (cs) |
| HK (1) | HK1001089A1 (cs) |
| HU (1) | HU220222B (cs) |
| NO (1) | NO305551B1 (cs) |
| RU (1) | RU2098406C1 (cs) |
| WO (1) | WO1993009085A1 (cs) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5925658A (en) * | 1995-03-02 | 1999-07-20 | Sankyo Company, Limited | Optically active thiazolidinone derivative |
| PE20061335A1 (es) * | 2005-04-22 | 2006-12-29 | Wyeth Corp | Compuestos derivados de benzodioxano y benzodioxolano como moduladores del receptor 5-ht2c |
| US8492428B2 (en) | 2005-09-20 | 2013-07-23 | Mayo Foundation For Medical Education And Research | Small-molecule botulinum toxin inhibitors |
| NL2000351C2 (nl) * | 2005-12-22 | 2007-09-11 | Pfizer Prod Inc | Estrogeen-modulatoren. |
| KR100698701B1 (ko) * | 2006-03-28 | 2007-03-23 | 삼성에스디아이 주식회사 | 유기전계발광 표시장치 및 그의 구동방법 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4200640A (en) * | 1976-04-02 | 1980-04-29 | Chugai Seiyaku Kabushiki Kaisha | Nitric ester of N-(2-hydroxyethyl)nicotinamide and pharmaceutical use |
| JPS539775A (en) * | 1976-07-15 | 1978-01-28 | Chugai Pharmaceut Co Ltd | Pyridine derivatives and their preparation |
| JPS57197275A (en) * | 1981-05-29 | 1982-12-03 | Nippon Zeon Co Ltd | Production of alpha-lactone |
| DE3443998A1 (de) * | 1984-12-01 | 1986-06-05 | Boehringer Mannheim Gmbh, 6800 Mannheim | Amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| JPS62286968A (ja) * | 1986-06-04 | 1987-12-12 | Chugai Pharmaceut Co Ltd | 新規ニコチン酸アミド誘導体 |
| DE3705622A1 (de) * | 1987-02-21 | 1988-09-01 | Boehringer Mannheim Gmbh | Neue amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
| GB8717068D0 (en) * | 1987-07-20 | 1987-08-26 | Fujisawa Pharmaceutical Co | Nitric ester derivative |
| JPS6456667A (en) * | 1987-08-28 | 1989-03-03 | Hokuriku Pharmaceutical | Nitric acid ester derivative |
| NL8802276A (nl) * | 1988-09-15 | 1990-04-02 | Cedona Pharm Bv | Geneesmiddel met relaxerende werking, dat als aktieve stof een nitraatester bevat. |
| JPH02207072A (ja) * | 1989-02-06 | 1990-08-16 | Sagami Kasei Kogyo Kk | ピリジンカルボン酸アミドアルコール類の硝酸エステル化法 |
| AU647599B2 (en) * | 1991-03-27 | 1994-03-24 | Sankyo Company Limited | New thiazolidinone and oxazolidinone derivatives, their preparation and their use as vasodilators |
| JP2777000B2 (ja) * | 1991-06-27 | 1998-07-16 | ローム株式会社 | イメージセンサ |
| JP3361836B2 (ja) * | 1991-07-04 | 2003-01-07 | 三共株式会社 | アミノ酸誘導体 |
-
1992
- 1992-10-30 JP JP29280092A patent/JP3454531B2/ja not_active Expired - Fee Related
- 1992-11-02 CZ CZ941106A patent/CZ281710B6/cs not_active IP Right Cessation
- 1992-11-02 WO PCT/JP1992/001419 patent/WO1993009085A1/ja active IP Right Grant
- 1992-11-02 RU RU9494026250A patent/RU2098406C1/ru not_active IP Right Cessation
- 1992-11-02 AU AU28736/92A patent/AU662939B2/en not_active Ceased
- 1992-11-02 US US08/211,904 patent/US5580893A/en not_active Expired - Fee Related
- 1992-11-02 HK HK98100098A patent/HK1001089A1/en not_active IP Right Cessation
- 1992-11-02 FI FI942070A patent/FI942070A0/fi not_active Application Discontinuation
- 1992-11-02 EP EP92922600A patent/EP0641768B1/en not_active Expired - Lifetime
- 1992-11-02 KR KR1019940701515A patent/KR100230633B1/ko not_active Expired - Fee Related
- 1992-11-02 ES ES92922600T patent/ES2106199T3/es not_active Expired - Lifetime
- 1992-11-02 AT AT92922600T patent/ATE155774T1/de not_active IP Right Cessation
- 1992-11-02 DK DK92922600.9T patent/DK0641768T3/da active
- 1992-11-02 DE DE69221167T patent/DE69221167T2/de not_active Expired - Fee Related
- 1992-11-02 HU HU9401399A patent/HU220222B/hu not_active IP Right Cessation
- 1992-11-02 CA CA002123101A patent/CA2123101C/en not_active Expired - Fee Related
-
1994
- 1994-05-06 NO NO941697A patent/NO305551B1/no not_active IP Right Cessation
-
1997
- 1997-10-15 GR GR970402702T patent/GR3025056T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP3454531B2 (ja) | 2003-10-06 |
| NO305551B1 (no) | 1999-06-21 |
| EP0641768A1 (en) | 1995-03-08 |
| AU662939B2 (en) | 1995-09-21 |
| AU2873692A (en) | 1993-06-07 |
| FI942070A7 (fi) | 1994-05-05 |
| CZ110694A3 (en) | 1995-03-15 |
| HU9401399D0 (en) | 1994-08-29 |
| US5580893A (en) | 1996-12-03 |
| EP0641768A4 (en) | 1994-12-22 |
| FI942070L (fi) | 1994-05-05 |
| CA2123101A1 (en) | 1993-05-13 |
| WO1993009085A1 (fr) | 1993-05-13 |
| NO941697D0 (no) | 1994-05-06 |
| CA2123101C (en) | 2001-10-30 |
| DK0641768T3 (da) | 1998-02-16 |
| CZ281710B6 (cs) | 1996-12-11 |
| EP0641768B1 (en) | 1997-07-23 |
| RU2098406C1 (ru) | 1997-12-10 |
| ES2106199T3 (es) | 1997-11-01 |
| DE69221167D1 (de) | 1997-08-28 |
| NO941697L (cs) | 1994-06-24 |
| GR3025056T3 (en) | 1998-01-30 |
| HU220222B (hu) | 2001-11-28 |
| DE69221167T2 (de) | 1998-02-19 |
| HUT73786A (en) | 1996-09-30 |
| KR100230633B1 (ko) | 1999-11-15 |
| ATE155774T1 (de) | 1997-08-15 |
| FI942070A0 (fi) | 1994-05-05 |
| JPH05271173A (ja) | 1993-10-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PF | Patent in force | ||
| PC | Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee) |
Effective date: 20051102 |