GR851678B - - Google Patents

Info

Publication number
GR851678B
GR851678B GR851678A GR850101678A GR851678B GR 851678 B GR851678 B GR 851678B GR 851678 A GR851678 A GR 851678A GR 850101678 A GR850101678 A GR 850101678A GR 851678 B GR851678 B GR 851678B
Authority
GR
Greece
Application number
GR851678A
Inventor
Terence M Dolak
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of GR851678B publication Critical patent/GR851678B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/84—Nitriles
    • C07D213/85—Nitriles in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
GR851678A 1984-07-11 1985-07-05 GR851678B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/629,649 US4585773A (en) 1984-07-11 1984-07-11 Isoindolinyl-alkyl-piperazines

Publications (1)

Publication Number Publication Date
GR851678B true GR851678B (el) 1985-11-26

Family

ID=24523882

Family Applications (1)

Application Number Title Priority Date Filing Date
GR851678A GR851678B (el) 1984-07-11 1985-07-05

Country Status (25)

Country Link
US (1) US4585773A (el)
JP (2) JPS6136260A (el)
KR (1) KR870000355B1 (el)
AT (1) AT385270B (el)
AU (1) AU584104B2 (el)
BE (1) BE902847A (el)
CA (1) CA1255311A (el)
CH (1) CH664964A5 (el)
DE (1) DE3524635A1 (el)
DK (2) DK163057C (el)
ES (2) ES8705425A1 (el)
FI (1) FI79837C (el)
FR (1) FR2567519B1 (el)
GB (1) GB2161807B (el)
GR (1) GR851678B (el)
HU (1) HU195213B (el)
IE (1) IE58787B1 (el)
IT (1) IT1187756B (el)
LU (1) LU85999A1 (el)
MY (1) MY102973A (el)
NL (1) NL8501998A (el)
NO (1) NO163775C (el)
PT (1) PT80794B (el)
SE (1) SE457449B (el)
ZA (1) ZA855092B (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5962490A (en) * 1987-09-25 1999-10-05 Texas Biotechnology Corporation Thienyl-, furyl- and pyrrolyl-sulfonamides and derivatives thereof that modulate the activity of endothelin
FR2628425B1 (fr) * 1988-03-08 1992-04-03 Rhone Poulenc Sante Derives d'isoindolinone, leurs procedes de preparation et les medicaments les contenant
WO1990002552A1 (en) * 1988-09-16 1990-03-22 Pfizer Inc. Antipsychotic 4-[4-(3-benzisothiazolyl)-1-piperazinyl]butyl bridged bicyclic imides
US5332733A (en) * 1990-11-24 1994-07-26 Kali-Chemie Pharma Gmbh Heterocyclically substituted piperazinoakylbenzoxazine and piperazinoalkylbenzothiazine compounds, processes for preparing them, and medicaments containing them
US5605896A (en) * 1992-02-25 1997-02-25 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities
IT1254469B (it) * 1992-02-25 1995-09-25 Recordati Chem Pharm Derivati benzopiranici e benzotiopiranici
US5474994A (en) * 1992-05-26 1995-12-12 Recordati S.A., Chemical And Pharmaceutical Company Bicyclic heterocyclic derivatives having α1 -adrenergic and 5HT1A
IT1258315B (it) * 1992-04-10 1996-02-22 Recordati Chem Pharm Derivati del flavone
US5804585A (en) * 1996-04-15 1998-09-08 Texas Biotechnology Corporation Thieno-pyridine sulfonamides derivatives thereof and related compounds that modulate the activity of endothelin
US6387909B1 (en) 1999-07-30 2002-05-14 Recordati S.A. Chemical And Pharmaceutical Company Thienopyranecarboxamide derivatives
US6306861B1 (en) 1999-07-30 2001-10-23 Recordati S.A. Chemical And Pharmaceutical Company Thienopyrancecarboxamide derivatives
ITMI20012060A1 (it) * 2001-10-05 2003-04-05 Recordati Chem Pharm Nuovi eterocilcli n-acilati
US20130203756A1 (en) * 2010-10-29 2013-08-08 Jamie L. Bunda Isoindoline pde10 inhibitors
CN115417772A (zh) * 2022-09-26 2022-12-02 无锡双启科技有限公司 一种3-硝基-4-氟苯甲醚的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1264070A (fr) * 1959-05-08 1961-06-19 Knoll Ag Procédé de préparation de dérivés de la phtalimidine et produits conformes à ceux obtenus
DE1135461B (de) * 1959-05-08 1962-08-30 Knoll Ag Verfahren zur Herstellung von basisch substituierten Phthalimidinen
US3198798A (en) * 1962-11-02 1965-08-03 Sterling Drug Inc Phthalimido- and isoindolinyl-alkylpiperazines and their preparation
US3579524A (en) * 1968-06-05 1971-05-18 Miles Lab 2-aminoalkyl derivatives of phthalimidines
SE368009B (el) * 1971-09-16 1974-06-17 Kabi Ab
IL52413A (en) * 1977-06-29 1980-01-31 Teva Pharma Process for the preparazione of 5-chloro-6-sulfamyl-isoindolinone derivatives
SE7907121L (sv) * 1979-08-27 1981-02-28 Astra Laekemedel Ab Ftalimidinderivat
US4524206A (en) * 1983-09-12 1985-06-18 Mead Johnson & Company 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives
US4505911A (en) * 1983-10-13 1985-03-19 Mead Johnson & Company Isoindole diuretic derivatives, compositions and use

Also Published As

Publication number Publication date
HU195213B (en) 1988-04-28
NO163775B (no) 1990-04-09
ZA855092B (en) 1986-02-26
MY102973A (en) 1993-03-31
FR2567519A1 (fr) 1986-01-17
DK6691A (da) 1991-01-14
AT385270B (de) 1988-03-10
ES545003A0 (es) 1987-05-01
IE58787B1 (en) 1993-11-17
DK315085A (da) 1986-01-12
ES8707525A1 (es) 1987-08-01
JPS6136260A (ja) 1986-02-20
PT80794A (en) 1985-08-01
CA1255311A (en) 1989-06-06
KR860001098A (ko) 1986-02-22
ES8705425A1 (es) 1987-05-01
PT80794B (pt) 1987-10-20
FI79837B (fi) 1989-11-30
SE457449B (sv) 1988-12-27
JPS61178964A (ja) 1986-08-11
GB2161807B (en) 1987-12-09
SE8503415L (sv) 1986-01-12
LU85999A1 (fr) 1986-02-12
FR2567519B1 (fr) 1990-04-13
JPH0466B2 (el) 1992-01-06
FI852694A0 (fi) 1985-07-08
DK6691D0 (da) 1991-01-14
FI79837C (fi) 1990-03-12
GB2161807A (en) 1986-01-22
DK163057B (da) 1992-01-13
DE3524635A1 (de) 1986-01-23
IT8521498A0 (it) 1985-07-10
DK163057C (da) 1992-06-09
DK315085D0 (da) 1985-07-10
AU584104B2 (en) 1989-05-18
NO852779L (no) 1986-01-13
IE851734L (en) 1986-01-11
BE902847A (fr) 1986-01-10
NO163775C (no) 1990-07-18
ES552108A0 (es) 1987-08-01
US4585773A (en) 1986-04-29
IT1187756B (it) 1987-12-23
CH664964A5 (de) 1988-04-15
NL8501998A (nl) 1986-02-03
SE8503415D0 (sv) 1985-07-09
GB8517418D0 (en) 1985-08-14
HUT39177A (en) 1986-08-28
FI852694L (fi) 1986-01-12
ATA206285A (de) 1987-08-15
AU4476485A (en) 1986-01-16
KR870000355B1 (ko) 1987-03-05

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