GR70219B - - Google Patents

Info

Publication number
GR70219B
GR70219B GR63068A GR800163068A GR70219B GR 70219 B GR70219 B GR 70219B GR 63068 A GR63068 A GR 63068A GR 800163068 A GR800163068 A GR 800163068A GR 70219 B GR70219 B GR 70219B
Authority
GR
Greece
Application number
GR63068A
Inventor
Billy Grinnell Jackson
Donna Nezich Gardner
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of GR70219B publication Critical patent/GR70219B/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/12—Separation; Purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GR63068A 1979-10-09 1980-10-07 GR70219B (el)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/082,822 US4252951A (en) 1979-10-09 1979-10-09 Isolation of syn-7-(2-amino-4-thiazolyl)-(methoxyimino)acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid

Publications (1)

Publication Number Publication Date
GR70219B true GR70219B (el) 1982-08-31

Family

ID=22173679

Family Applications (1)

Application Number Title Priority Date Filing Date
GR63068A GR70219B (el) 1979-10-09 1980-10-07

Country Status (27)

Country Link
US (1) US4252951A (el)
EP (1) EP0027050B1 (el)
JP (1) JPS5661388A (el)
KR (1) KR840000866B1 (el)
AT (1) AT369008B (el)
AU (1) AU6306180A (el)
BE (1) BE885569A (el)
CA (1) CA1146539A (el)
CH (1) CH647523A5 (el)
CS (1) CS215142B2 (el)
DD (1) DD153375A5 (el)
DE (1) DE3065181D1 (el)
DK (1) DK424680A (el)
ES (1) ES8201166A1 (el)
FI (1) FI803200L (el)
FR (1) FR2467211A1 (el)
GB (1) GB2059966B (el)
GR (1) GR70219B (el)
HU (1) HU183230B (el)
IE (1) IE50390B1 (el)
IL (1) IL61227A (el)
IT (1) IT1132926B (el)
PH (1) PH15023A (el)
PT (1) PT71886B (el)
RO (1) RO80664B (el)
YU (1) YU256480A (el)
ZA (1) ZA806192B (el)

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JPH07116200B2 (ja) * 1985-09-20 1995-12-13 富山化学工業株式会社 セファロスポリンの製造方法
JPH08831B2 (ja) * 1985-09-20 1996-01-10 富山化学工業株式会社 セファロスポリンの精製法
ES2305606T3 (es) * 1999-04-06 2008-11-01 Sepracor Inc. Succinato de o-desmetilvenlafaxina.
ATE504572T1 (de) * 1999-09-02 2011-04-15 Shionogi & Co Derivate von aromatische heterocyclen enthaltende integraseinhibitoren
CA2284459C (en) 1999-10-04 2012-12-11 Neokimia Inc. Combinatorial synthesis of libraries of macrocyclic compounds useful in drug discovery
JP4879433B2 (ja) * 2000-01-13 2012-02-22 エミスフェアー・テクノロジーズ・インク 活性剤を送達するための化合物および組成物
CN102295744B (zh) * 2001-03-08 2014-07-02 宾夕法尼亚州大学理事会 作为抗感染药的表面两亲聚合物
MXPA04001831A (es) * 2001-08-29 2004-07-08 Neose Technologies Inc Nuevos derivados sinteticos de gangliosidos y composiciones de los mismos.
BR0314455A (pt) * 2002-09-19 2005-07-26 Kyorin Seiyaku Kk Derivados de aminoálcool, seus sais e agentes imunosupressores
US7056916B2 (en) * 2002-11-15 2006-06-06 Boehringer Ingelheim Pharma Gmbh & Co. Kg Medicaments for the treatment of chronic obstructive pulmonary disease
US9241917B2 (en) * 2003-03-17 2016-01-26 The Trustees Of The University Of Pennsylvania Facially amphiphilic polymers and oligomers and uses thereof
US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
US20050203184A1 (en) 2003-09-10 2005-09-15 Petasis Nicos A. Benzo lipoxin analogues
AU2005208771B2 (en) 2004-01-23 2011-11-24 The Trustees Of The University Of Pennsylvania Facially amphiphilic polyaryl and polyarylalkynyl polymers and oligomers and uses thereof
BRPI0510715A (pt) * 2004-05-06 2007-11-20 Univ California enaminonas substituìdas, seus derivados e usos destas
US20050255050A1 (en) * 2004-05-14 2005-11-17 Boehringer Ingelheim International Gmbh Powder formulations for inhalation, comprising enantiomerically pure beta agonists
US7220742B2 (en) * 2004-05-14 2007-05-22 Boehringer Ingelheim International Gmbh Enantiomerically pure beta agonists, process for the manufacture thereof and use thereof as medicaments
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
US20060241052A1 (en) * 2005-02-25 2006-10-26 Degrado William F Facially amphiphilic polymers and oligomers, compositions thereof, and use thereof in methods of treating cancer
US7893304B2 (en) * 2005-02-28 2011-02-22 Meiji Dairies Corporation Hydroquinone long-chain derivatives and/or phenoxy long-chain derivatives, and pharmaceuticals comprising the same
BRPI0614805A2 (pt) * 2005-08-10 2011-04-12 Univ Johns Hopkins poliaminas úteis como produtos terapêuticos antiparasìticos e anticáncer e como inibidores de demetilase lisina-especìficos
AU2006281449B2 (en) * 2005-08-15 2013-01-31 Boehringer Ingelheim International Gmbh Method for producing betamimetics
EP1940844B1 (en) * 2005-10-28 2009-09-30 Irm Llc Compounds and compositions as protein kinase inhibitors
EP1954259A2 (en) * 2005-11-29 2008-08-13 Hammersmith Imanet, Ltd Amidine derivatives for in vivo imaging
ES2288107B1 (es) * 2006-01-27 2008-11-01 Fundacion Imabis Instituto Mediterraneo Para El Avance De La Biotecnologia Y La Investigacion Sanita Derivados aciclicos saturados e insaturados de cadena larga de sulfamidas como activadores especificos de receptores ppar-alfa.
FR2903004B1 (fr) * 2006-07-03 2009-07-10 Oreal Utilisation en cosmetique d'un derive c-glycoside en association avec de l'acide ascorbique
FR2902999B1 (fr) * 2006-07-03 2012-09-28 Oreal Utilisation de derives c-glycoside a titre d'actif prodesquamant
FR2902996B1 (fr) * 2006-07-03 2008-09-26 Oreal Compositions cosmetiques associant un derive c-glycoside et un derive n-acylaminoamide
US20090075935A1 (en) * 2006-07-03 2009-03-19 L'oreal Composition comprising at least one c-glycoside derivative and at least one hyaluronic acid and its cosmetic use
PL2101569T3 (pl) * 2006-12-14 2012-03-30 Teva Pharma Stała, krystaliczna zasada rasagaliny
CN104844678B (zh) 2007-05-11 2018-02-09 香港科技大学 具有神经保护和增强记忆活性的受体调节剂
US7696383B2 (en) * 2007-06-26 2010-04-13 Solvay Pharmaceuticals B.V. N-oxides of venlafaxine and o-desmethylvenlafaxine as prodrugs
FR2920000B1 (fr) * 2007-08-13 2010-01-29 Oreal Composition cosmetique ou pharmaceutique contenant de l'acide hyaluronique, et procede cosmetique pour diminuer les signes du vieilissement
KR101618068B1 (ko) * 2007-10-19 2016-05-04 얀센 파마슈티카 엔.브이. γ-세크레타아제의 탄소 결합된 조절제
MX2010004309A (es) * 2007-10-19 2010-05-03 Janssen Pharmaceutica Nv Moduladores de piperidinil y piperazinil de gamma-secretasa.
MX2010004318A (es) * 2007-10-19 2010-04-30 Janssen Pharmaceutica Nv Moduladores de la gamma-secretasa con enlaces de amina.
EP2093207A1 (en) * 2008-02-06 2009-08-26 Julius-Maximilians-Universität Würzburg Antiinfective and antitumoral compounds isolated from tropical lianas
US8063249B1 (en) * 2008-04-25 2011-11-22 Olema Pharmaceuticals, Inc. Substituted triphenyl butenes
WO2010017328A2 (en) * 2008-08-06 2010-02-11 Rgo Biosciences Llc Cyclodextrin conjugates
KR101546562B1 (ko) 2008-10-22 2015-08-25 어큐셀라 인코포레이티드 안과 질환 및 장애 치료용 화합물
FR2940610B1 (fr) * 2008-12-30 2011-05-06 Oreal Association de monosaccharides avec des derives c-glycosides et son utilisation en cosmetique
US20120035120A1 (en) 2009-03-25 2012-02-09 Seneb Biosciences, Inc. Glycolipids as treatment for disease
UA108986C2 (uk) * 2009-05-14 2015-07-10 Мілленніум Фармасьютікалз, Інк. Кристалічна форма гідрохлориду ((1s,2s,4r)-4-{4-[(1s)-2,3-дигідро-1h-інден-1-іламіно]-7h-піроло[2,3-d]піримідин-7іл}-2-гідроксициклопентил)метилсульфамату (варіанти)
US8962639B2 (en) * 2009-05-29 2015-02-24 Abbvie Inc. Potassium channel modulators
US8288592B2 (en) * 2009-09-22 2012-10-16 Actavis Group Ptc Ehf Solid state forms of tapentadol salts
WO2012067824A1 (en) 2010-11-16 2012-05-24 Abbott Laboratories Potassium channel modulators
EA029151B1 (ru) * 2011-09-06 2018-02-28 Курна, Инк. ЛЕЧЕНИЕ ЗАБОЛЕВАНИЙ, СВЯЗАННЫХ С АЛЬФА-СУБЪЕДИНИЦАМИ ПОТЕНЦИАЛЗАВИСИМЫХ НАТРИЕВЫХ КАНАЛОВ (SCNxA), С ПОМОЩЬЮ МАЛЫХ МОЛЕКУЛ
US8377946B1 (en) 2011-12-30 2013-02-19 Pharmacyclics, Inc. Pyrazolo[3,4-d]pyrimidine and pyrrolo[2,3-d]pyrimidine compounds as kinase inhibitors

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
US4166115A (en) * 1976-04-12 1979-08-28 Fujisawa Pharmaceutical Co., Ltd. Syn 7-oxoimino substituted derivatives of cephalosporanic acid

Also Published As

Publication number Publication date
DD153375A5 (de) 1982-01-06
IT1132926B (it) 1986-07-09
DE3065181D1 (en) 1983-11-10
KR830004314A (ko) 1983-07-09
US4252951A (en) 1981-02-24
JPS5661388A (en) 1981-05-26
CH647523A5 (fr) 1985-01-31
YU256480A (en) 1983-02-28
CS215142B2 (en) 1982-07-30
IL61227A0 (en) 1980-12-31
PT71886B (en) 1981-08-13
IL61227A (en) 1983-07-31
KR840000866B1 (ko) 1984-06-20
ES495753A0 (es) 1981-12-01
DK424680A (da) 1981-04-10
HU183230B (en) 1984-04-28
EP0027050B1 (en) 1983-10-05
FR2467211A1 (fr) 1981-04-17
CA1146539A (en) 1983-05-17
ATA498080A (de) 1982-04-15
IT8025200A0 (it) 1980-10-08
ES8201166A1 (es) 1981-12-01
AT369008B (de) 1982-11-25
IE50390B1 (en) 1986-04-16
PH15023A (en) 1982-05-13
IE802086L (en) 1981-04-09
PT71886A (en) 1980-11-01
FI803200L (fi) 1981-04-10
GB2059966A (en) 1981-04-29
RO80664B (ro) 1983-02-28
ZA806192B (en) 1982-05-26
RO80664A (ro) 1983-02-15
AU6306180A (en) 1981-04-16
GB2059966B (en) 1983-09-01
EP0027050A1 (en) 1981-04-15
FR2467211B1 (el) 1983-06-10
BE885569A (fr) 1981-04-08

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