YU256480A - Process for obtaining the solvate of syn-7-2-(2-amino-4-thiazolyl)-2-methxy-imino-acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid and the alicyclic ether in solid form - Google Patents

Process for obtaining the solvate of syn-7-2-(2-amino-4-thiazolyl)-2-methxy-imino-acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid and the alicyclic ether in solid form

Info

Publication number
YU256480A
YU256480A YU02564/80A YU256480A YU256480A YU 256480 A YU256480 A YU 256480A YU 02564/80 A YU02564/80 A YU 02564/80A YU 256480 A YU256480 A YU 256480A YU 256480 A YU256480 A YU 256480A
Authority
YU
Yugoslavia
Prior art keywords
methxy
cephem
acetoxymethyl
acetamido
syn
Prior art date
Application number
YU02564/80A
Other languages
English (en)
Inventor
B G Jackson
D N Gardner
D Nezich
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of YU256480A publication Critical patent/YU256480A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/12—Separation; Purification
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
    • C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
YU02564/80A 1979-10-09 1980-10-07 Process for obtaining the solvate of syn-7-2-(2-amino-4-thiazolyl)-2-methxy-imino-acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid and the alicyclic ether in solid form YU256480A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/082,822 US4252951A (en) 1979-10-09 1979-10-09 Isolation of syn-7-(2-amino-4-thiazolyl)-(methoxyimino)acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid

Publications (1)

Publication Number Publication Date
YU256480A true YU256480A (en) 1983-02-28

Family

ID=22173679

Family Applications (1)

Application Number Title Priority Date Filing Date
YU02564/80A YU256480A (en) 1979-10-09 1980-10-07 Process for obtaining the solvate of syn-7-2-(2-amino-4-thiazolyl)-2-methxy-imino-acetamido-3-acetoxymethyl-3-cephem-4-carboxylic acid and the alicyclic ether in solid form

Country Status (27)

Country Link
US (1) US4252951A (xx)
EP (1) EP0027050B1 (xx)
JP (1) JPS5661388A (xx)
KR (1) KR840000866B1 (xx)
AT (1) AT369008B (xx)
AU (1) AU6306180A (xx)
BE (1) BE885569A (xx)
CA (1) CA1146539A (xx)
CH (1) CH647523A5 (xx)
CS (1) CS215142B2 (xx)
DD (1) DD153375A5 (xx)
DE (1) DE3065181D1 (xx)
DK (1) DK424680A (xx)
ES (1) ES495753A0 (xx)
FI (1) FI803200L (xx)
FR (1) FR2467211A1 (xx)
GB (1) GB2059966B (xx)
GR (1) GR70219B (xx)
HU (1) HU183230B (xx)
IE (1) IE50390B1 (xx)
IL (1) IL61227A (xx)
IT (1) IT1132926B (xx)
PH (1) PH15023A (xx)
PT (1) PT71886B (xx)
RO (1) RO80664B (xx)
YU (1) YU256480A (xx)
ZA (1) ZA806192B (xx)

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CA2498944C (en) * 2002-09-19 2011-05-17 Yasushi Kohno Amino alcohol derivatives, salts thereof and immunosuppressive agents
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US7321065B2 (en) * 2003-04-18 2008-01-22 The Regents Of The University Of California Thyronamine derivatives and analogs and methods of use thereof
US20050203184A1 (en) 2003-09-10 2005-09-15 Petasis Nicos A. Benzo lipoxin analogues
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US7825278B2 (en) * 2004-05-06 2010-11-02 The Regents Of The University Of California Substituted enaminones, their derivatives and uses thereof
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TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
JP2008531585A (ja) * 2005-02-25 2008-08-14 ザ・トラステイーズ・オブ・ザ・ユニバーシテイ・オブ・ペンシルベニア 表面が両親媒性のポリマーおよびオリゴマー、それらの組成物そして癌治療方法におけるそれらの使用
CN101166706B (zh) * 2005-02-28 2011-08-24 明治乳业株式会社 氢醌长链衍生物和/或苯氧基长链衍生物及含有它们的药品
AU2006279943B2 (en) * 2005-08-10 2012-02-16 The Johns Hopkins University Polyamines useful as anti-parasitic and anti-cancer therapeutics and as lysine-specific demethylase inhibitors
JP5270343B2 (ja) * 2005-08-15 2013-08-21 ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング ベータミメティックスの製造方法
US8592433B2 (en) * 2005-10-28 2013-11-26 Advait Nagle Compounds and compositions as protein kinase inhibitors
EP1954259A2 (en) * 2005-11-29 2008-08-13 Hammersmith Imanet, Ltd Amidine derivatives for in vivo imaging
ES2288107B1 (es) * 2006-01-27 2008-11-01 Fundacion Imabis Instituto Mediterraneo Para El Avance De La Biotecnologia Y La Investigacion Sanita Derivados aciclicos saturados e insaturados de cadena larga de sulfamidas como activadores especificos de receptores ppar-alfa.
FR2903004B1 (fr) * 2006-07-03 2009-07-10 Oreal Utilisation en cosmetique d'un derive c-glycoside en association avec de l'acide ascorbique
FR2902996B1 (fr) * 2006-07-03 2008-09-26 Oreal Compositions cosmetiques associant un derive c-glycoside et un derive n-acylaminoamide
US20090075935A1 (en) * 2006-07-03 2009-03-19 L'oreal Composition comprising at least one c-glycoside derivative and at least one hyaluronic acid and its cosmetic use
FR2902999B1 (fr) * 2006-07-03 2012-09-28 Oreal Utilisation de derives c-glycoside a titre d'actif prodesquamant
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FR2920000B1 (fr) * 2007-08-13 2010-01-29 Oreal Composition cosmetique ou pharmaceutique contenant de l'acide hyaluronique, et procede cosmetique pour diminuer les signes du vieilissement
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Also Published As

Publication number Publication date
JPS5661388A (en) 1981-05-26
KR840000866B1 (ko) 1984-06-20
RO80664A (ro) 1983-02-15
IL61227A (en) 1983-07-31
PT71886B (en) 1981-08-13
ES8201166A1 (es) 1981-12-01
EP0027050A1 (en) 1981-04-15
EP0027050B1 (en) 1983-10-05
IE50390B1 (en) 1986-04-16
DK424680A (da) 1981-04-10
PH15023A (en) 1982-05-13
CS215142B2 (en) 1982-07-30
IT8025200A0 (it) 1980-10-08
DE3065181D1 (en) 1983-11-10
GB2059966A (en) 1981-04-29
KR830004314A (ko) 1983-07-09
ATA498080A (de) 1982-04-15
HU183230B (en) 1984-04-28
AT369008B (de) 1982-11-25
ES495753A0 (es) 1981-12-01
FI803200L (fi) 1981-04-10
FR2467211B1 (xx) 1983-06-10
BE885569A (fr) 1981-04-08
CA1146539A (en) 1983-05-17
IL61227A0 (en) 1980-12-31
GR70219B (xx) 1982-08-31
IE802086L (en) 1981-04-09
GB2059966B (en) 1983-09-01
DD153375A5 (de) 1982-01-06
AU6306180A (en) 1981-04-16
IT1132926B (it) 1986-07-09
CH647523A5 (fr) 1985-01-31
PT71886A (en) 1980-11-01
RO80664B (ro) 1983-02-28
FR2467211A1 (fr) 1981-04-17
US4252951A (en) 1981-02-24
ZA806192B (en) 1982-05-26

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