GR3005934T3 - - Google Patents
Info
- Publication number
- GR3005934T3 GR3005934T3 GR920402254T GR920402254T GR3005934T3 GR 3005934 T3 GR3005934 T3 GR 3005934T3 GR 920402254 T GR920402254 T GR 920402254T GR 920402254 T GR920402254 T GR 920402254T GR 3005934 T3 GR3005934 T3 GR 3005934T3
- Authority
- GR
- Greece
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
- C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/10—Seven-membered rings having the hetero atoms in positions 1 and 4 not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10155286 | 1986-04-30 | ||
| JP31509086 | 1986-12-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3005934T3 true GR3005934T3 (cg-RX-API-DMAC10.html) | 1993-06-07 |
Family
ID=26442419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR920402254T GR3005934T3 (cg-RX-API-DMAC10.html) | 1986-04-30 | 1992-10-12 |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4870074A (cg-RX-API-DMAC10.html) |
| EP (1) | EP0243959B1 (cg-RX-API-DMAC10.html) |
| KR (1) | KR870010030A (cg-RX-API-DMAC10.html) |
| AR (1) | AR242953A1 (cg-RX-API-DMAC10.html) |
| AU (1) | AU592177B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA1291135C (cg-RX-API-DMAC10.html) |
| CZ (1) | CZ284687B6 (cg-RX-API-DMAC10.html) |
| DE (1) | DE3781195T2 (cg-RX-API-DMAC10.html) |
| DK (1) | DK175281B1 (cg-RX-API-DMAC10.html) |
| ES (1) | ES2043617T3 (cg-RX-API-DMAC10.html) |
| FI (1) | FI87776C (cg-RX-API-DMAC10.html) |
| GR (1) | GR3005934T3 (cg-RX-API-DMAC10.html) |
| HK (1) | HK18194A (cg-RX-API-DMAC10.html) |
| HU (1) | HU198193B (cg-RX-API-DMAC10.html) |
| NZ (1) | NZ220120A (cg-RX-API-DMAC10.html) |
| PH (1) | PH24049A (cg-RX-API-DMAC10.html) |
| SK (1) | SK289787A3 (cg-RX-API-DMAC10.html) |
| SU (1) | SU1597101A3 (cg-RX-API-DMAC10.html) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2640139A1 (fr) * | 1988-12-14 | 1990-06-15 | Delagrange Laboratoires | Application de benzamides substitues comme gastromoteurs |
| US5395832A (en) * | 1991-02-15 | 1995-03-07 | Hokuriku Seiyaku Co., Ltd. | Benzamide derivatives |
| TW213460B (cg-RX-API-DMAC10.html) * | 1991-02-15 | 1993-09-21 | Hokuriku Pharmaceutical | |
| US5864039A (en) * | 1994-03-30 | 1999-01-26 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzoic acid compounds and use thereof as medicaments |
| EP0774460A1 (en) * | 1994-03-30 | 1997-05-21 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzoic acid compound and use thereof as medicine |
| NZ309065A (en) * | 1995-05-23 | 1999-06-29 | Janssen Pharmaceutica Nv | (2-morpholinymethyl)benzamide derivatives having gastrointestinal motility stimulating properties |
| JP2001064177A (ja) * | 1999-08-16 | 2001-03-13 | Schering Ag | ベンズアミド誘導体を有効成分とする製剤 |
| BR0114323A (pt) | 2000-09-29 | 2003-07-01 | Glaxo Group Ltd | Composto ou um seu sal ou solvato farmaceuticamente aceitável, composição farmacêutica, uso do composto ou de um seu sal ou solvato farmaceuticamente aceitável, método de tratamento ou profilaxia de doenças inflamatórias, e, processo para preparar o composto |
| EP1353918B1 (en) * | 2000-11-28 | 2005-01-12 | Smithkline Beecham Plc | Morpholine derivatives as antagonists of orexin receptors |
| JP4829417B2 (ja) * | 2001-03-26 | 2011-12-07 | 明夫 乾 | インスリン抵抗性改善薬 |
| US20040265381A1 (en) * | 2001-10-08 | 2004-12-30 | Shanghvi Dilip S. | Anti-asthmatic drug (asmakure) from indigenous herbs to cure the disease asthma |
| GB0208158D0 (en) * | 2002-03-28 | 2002-05-22 | Glaxo Group Ltd | Novel compounds |
| GB0207449D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| GB0207447D0 (en) * | 2002-03-28 | 2002-05-08 | Glaxo Group Ltd | Novel compounds |
| HUP0201980A3 (en) * | 2002-06-13 | 2008-06-30 | Richter Gedeon Nyrt | Process for preparing a benzamide derivative and intermediates thereof |
| CN1913876B (zh) * | 2003-12-09 | 2013-06-26 | 大日本住友制药株式会社 | 含药物的颗粒和包含这种颗粒的固体制剂 |
| US8524736B2 (en) | 2004-01-07 | 2013-09-03 | Armetheon, Inc. | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| US8138204B2 (en) * | 2004-01-07 | 2012-03-20 | Aryx Therapeutics, Inc. | Stereoisomeric compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| PT2194053E (pt) * | 2004-01-07 | 2013-07-08 | Armetheon Inc | Derivados de metoxipiperidina para utilização no tratamento de distúrbios gastrointestinais e do sistema nervoso central |
| TW200619212A (en) | 2004-09-08 | 2006-06-16 | Mitsubishi Pharma Corp | Morpholine derivatives |
| WO2007002157A2 (en) | 2005-06-23 | 2007-01-04 | Array Biopharma Inc. | Process for preparing benzimidazole compounds |
| DK1919909T3 (da) * | 2005-08-31 | 2013-12-02 | Armetheon Inc | Syntesemetoder og mellemprodukter for stereoisomere forbindelser, der er anvendelige til behandling af gastrointestinale forstyrrelser og forstyrrelser i centralnervesystemet |
| WO2007075749A2 (en) * | 2005-12-20 | 2007-07-05 | Merck & Co., Inc. | Niacin receptor agonists, compositions containing such compounds and methods of treatment |
| KR100750593B1 (ko) * | 2006-03-16 | 2007-08-20 | 동우신테크 주식회사 | 치환된 벤즈아미드 유도체의 제조방법 |
| US20080085915A1 (en) * | 2006-06-23 | 2008-04-10 | Cyrus Becker | Compounds and methods for the treatment of gastrointestinal and central nervous system disorders |
| AU2008242703B2 (en) * | 2007-04-19 | 2011-08-18 | Concert Pharmaceuticals Inc. | Deuterated morpholinyl compounds |
| CN101402633A (zh) * | 2007-09-11 | 2009-04-08 | 上海恒瑞医药有限公司 | 苯甲酰胺类衍生物、其制备方法及其在医药上的用途 |
| JP4989733B2 (ja) | 2008-02-13 | 2012-08-01 | 大日本住友製薬株式会社 | 口腔内崩壊錠 |
| TWI423967B (zh) * | 2008-02-21 | 2014-01-21 | Dainippon Sumitomo Pharma Co | 醯胺衍生物及含有其之醫藥組合物 |
| CN102548542B (zh) | 2009-08-11 | 2013-11-20 | 大日本住友制药株式会社 | 含有两种以上粒子的口腔速崩片 |
| WO2011107903A1 (en) | 2010-03-04 | 2011-09-09 | Ranbaxy Laboratories Limited | Highly pure mosapride citrate dihydrate and processes for its preparation |
| AU2012221927B2 (en) | 2011-02-25 | 2016-04-28 | Yuhan Corporation | Diaminopyrimidine derivatives and processes for the preparation thereof |
| KR101657616B1 (ko) | 2013-05-24 | 2016-09-19 | 주식회사유한양행 | 피리미딘 고리를 포함하는 바이사이클릭 유도체 및 그의 제조방법 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Ｈｄａｃ抑制劑與ｐｄ-ｌ１抑制劑之組合治療 |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| CN111349052B (zh) * | 2020-04-07 | 2021-02-12 | 福建海西新药创制有限公司 | 一种枸橼酸莫沙必利的合成方法 |
| CN114560822B (zh) * | 2020-11-27 | 2024-05-28 | 鲁南制药集团股份有限公司 | 一种莫沙必利的二羧酸晶体 |
| CN114591260B (zh) * | 2020-12-05 | 2025-07-11 | 鲁南制药集团股份有限公司 | 一种莫沙必利有机酸盐 |
| CN119241463A (zh) * | 2024-10-22 | 2025-01-03 | 吉林修正药业新药开发有限公司 | 一种枸橼酸莫沙必利杂质化合物及其制备方法 |
| CN119241464A (zh) * | 2024-10-22 | 2025-01-03 | 吉林修正药业新药开发有限公司 | 一种枸橼酸莫沙必利杂质化合物及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH451142A (de) * | 1965-01-19 | 1968-05-15 | Sandoz Ag | Verfahren zur Herstellung neuer basisch substituierter Benzoesäureamide |
| US4029786A (en) * | 1972-08-11 | 1977-06-14 | Imperial Chemical Industries Limited | Morpholine derivatives for treating depression |
| US4323503A (en) * | 1976-08-04 | 1982-04-06 | Societe D'etudes Scientifiques Et Industrielles De L'ile-De-France | Substituted 2,3-alkylene di (oxy) benzamides and derivatives |
| US4210754A (en) * | 1977-02-01 | 1980-07-01 | Hoffmann-La Roche Inc. | Morpholino containing benzamides |
| US4692445A (en) * | 1983-04-29 | 1987-09-08 | Rorer Pharmaceutical Corporation | Bicyclic benzenoid aminoalkylene ethers and thioethers, pharmaceutical compositions and use |
| FR2575158B1 (fr) * | 1984-12-20 | 1987-10-02 | Pf Medicament | Arylalcoyloxymethyl-2 morpholines, leur preparation et leur application en tant que medicaments utiles dans le traitement des troubles du systeme nerveux central |
| JPH0390274A (ja) * | 1989-08-28 | 1991-04-16 | Furukawa Alum Co Ltd | Ａｌ又はＡｌ合金の気相ろう付法 |
-
1987
- 1987-04-24 CZ CS872897A patent/CZ284687B6/cs not_active IP Right Cessation
- 1987-04-24 SK SK2897-87A patent/SK289787A3/sk unknown
- 1987-04-24 US US07/042,474 patent/US4870074A/en not_active Expired - Lifetime
- 1987-04-27 FI FI871828A patent/FI87776C/fi not_active IP Right Cessation
- 1987-04-28 CA CA000535794A patent/CA1291135C/en not_active Expired - Lifetime
- 1987-04-28 NZ NZ220120A patent/NZ220120A/xx unknown
- 1987-04-29 EP EP87106266A patent/EP0243959B1/en not_active Expired - Lifetime
- 1987-04-29 PH PH35203A patent/PH24049A/en unknown
- 1987-04-29 DK DK198702187A patent/DK175281B1/da not_active IP Right Cessation
- 1987-04-29 ES ES87106266T patent/ES2043617T3/es not_active Expired - Lifetime
- 1987-04-29 HU HU871946A patent/HU198193B/hu unknown
- 1987-04-29 DE DE8787106266T patent/DE3781195T2/de not_active Expired - Lifetime
- 1987-04-29 SU SU874202484A patent/SU1597101A3/ru active
- 1987-04-30 KR KR870004220A patent/KR870010030A/ko not_active Withdrawn
- 1987-04-30 AU AU72275/87A patent/AU592177B2/en not_active Expired
- 1987-04-30 AR AR87307449A patent/AR242953A1/es active
-
1992
- 1992-10-12 GR GR920402254T patent/GR3005934T3/el unknown
-
1994
- 1994-03-03 HK HK181/94A patent/HK18194A/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA1291135C (en) | 1991-10-22 |
| PH24049A (en) | 1990-03-05 |
| AU592177B2 (en) | 1990-01-04 |
| DK218787D0 (da) | 1987-04-29 |
| CZ289787A3 (cs) | 1998-11-11 |
| DE3781195T2 (de) | 1993-02-18 |
| SK279058B6 (sk) | 1998-06-03 |
| DK175281B1 (da) | 2004-08-09 |
| FI87776B (fi) | 1992-11-13 |
| KR870010030A (ko) | 1987-11-30 |
| SK289787A3 (en) | 1998-06-03 |
| US4870074A (en) | 1989-09-26 |
| FI871828A7 (fi) | 1987-10-31 |
| DK218787A (da) | 1987-10-31 |
| FI871828A0 (fi) | 1987-04-27 |
| NZ220120A (en) | 1989-06-28 |
| HK18194A (en) | 1994-03-11 |
| AU7227587A (en) | 1987-11-05 |
| AR242953A1 (es) | 1993-06-30 |
| DE3781195D1 (de) | 1992-09-24 |
| FI87776C (fi) | 1993-02-25 |
| HUT45514A (en) | 1988-07-28 |
| EP0243959B1 (en) | 1992-08-19 |
| CZ284687B6 (cs) | 1999-02-17 |
| EP0243959A1 (en) | 1987-11-04 |
| SU1597101A3 (ru) | 1990-09-30 |
| ES2043617T3 (es) | 1994-01-01 |
| HU198193B (en) | 1989-08-28 |