GEP20125413B - Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1h-1, 2, 4-triazol-1-yl)-1-[(phosphonooxy) methyl]-1h-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine - Google Patents

Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1h-1, 2, 4-triazol-1-yl)-1-[(phosphonooxy) methyl]-1h-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine

Info

Publication number
GEP20125413B
GEP20125413B GEAP200610811A GEAP2006010811A GEP20125413B GE P20125413 B GEP20125413 B GE P20125413B GE AP200610811 A GEAP200610811 A GE AP200610811A GE AP2006010811 A GEAP2006010811 A GE AP2006010811A GE P20125413 B GEP20125413 B GE P20125413B
Authority
GE
Georgia
Prior art keywords
methyl
dioxoethyl
phosphonooxy
pyrrolo
triazol
Prior art date
Application number
GEAP200610811A
Other languages
English (en)
Inventor
Chung-Pin H Chen
Dawn Digiugno
Qi Gao
Chong-Hui Gu
Jaquan Kalani Levons
Bing-Shiou Yang
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of GEP20125413B publication Critical patent/GEP20125413B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GEAP200610811A 2005-12-14 2006-12-13 Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1h-1, 2, 4-triazol-1-yl)-1-[(phosphonooxy) methyl]-1h-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine GEP20125413B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75024705P 2005-12-14 2005-12-14

Publications (1)

Publication Number Publication Date
GEP20125413B true GEP20125413B (en) 2012-03-12

Family

ID=38163502

Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP200610811A GEP20125413B (en) 2005-12-14 2006-12-13 Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1h-1, 2, 4-triazol-1-yl)-1-[(phosphonooxy) methyl]-1h-pyrrolo[2,3-c]pyridin-3-yl]-1,2-dioxoethyl]-piperazine

Country Status (17)

Country Link
US (1) US7851476B2 (enExample)
EP (1) EP1963342A2 (enExample)
JP (1) JP5400387B2 (enExample)
KR (1) KR20080077010A (enExample)
CN (1) CN101365708B (enExample)
AU (1) AU2006326432B2 (enExample)
BR (1) BRPI0619851A2 (enExample)
CA (1) CA2635717A1 (enExample)
EA (1) EA014706B1 (enExample)
GE (1) GEP20125413B (enExample)
IL (1) IL191769A (enExample)
MY (1) MY144293A (enExample)
NO (1) NO20082477L (enExample)
NZ (2) NZ592684A (enExample)
UA (1) UA94928C2 (enExample)
WO (1) WO2007070589A2 (enExample)
ZA (1) ZA200805063B (enExample)

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KR102886764B1 (ko) 2019-06-06 2025-11-14 젠플리트 테라퓨틱스 (상하이) 아이엔씨. Cdk9 억제제의 결정다형 및 이의 제조방법과 용도
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Also Published As

Publication number Publication date
US7851476B2 (en) 2010-12-14
NZ592684A (en) 2012-07-27
AU2006326432B2 (en) 2012-07-12
ZA200805063B (en) 2009-10-28
NO20082477L (no) 2008-09-05
US20070155702A1 (en) 2007-07-05
IL191769A0 (en) 2008-12-29
UA94928C2 (en) 2011-06-25
WO2007070589A3 (en) 2007-09-27
NZ568776A (en) 2011-06-30
CN101365708A (zh) 2009-02-11
EA200801529A1 (ru) 2009-02-27
CA2635717A1 (en) 2007-06-21
CN101365708B (zh) 2012-12-12
KR20080077010A (ko) 2008-08-20
AU2006326432A1 (en) 2007-06-21
WO2007070589A2 (en) 2007-06-21
EA014706B1 (ru) 2011-02-28
MY144293A (en) 2011-08-29
EP1963342A2 (en) 2008-09-03
JP2009521414A (ja) 2009-06-04
JP5400387B2 (ja) 2014-01-29
BRPI0619851A2 (pt) 2011-10-25
IL191769A (en) 2011-08-31

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