GEP20012413B - Novel Substituted Cyclic Amino Acids as Pharmaceutical Agents - Google Patents

Novel Substituted Cyclic Amino Acids as Pharmaceutical Agents

Info

Publication number
GEP20012413B
GEP20012413B GEAP19974526A GEAP1997004526A GEP20012413B GE P20012413 B GEP20012413 B GE P20012413B GE AP19974526 A GEAP19974526 A GE AP19974526A GE AP1997004526 A GEAP1997004526 A GE AP1997004526A GE P20012413 B GEP20012413 B GE P20012413B
Authority
GE
Georgia
Prior art keywords
cyclic amino
amino acids
pharmaceutical agents
substituted cyclic
novel substituted
Prior art date
Application number
GEAP19974526A
Other languages
English (en)
Inventor
Gillws S Ratcliffe
Clare O Kneen
David Christopher Horwell
Johannes Hartenstein
Andrew I Morrel
Justin S Bryans
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of GEP20012413B publication Critical patent/GEP20012413B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/47—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A61P25/12—Antiepileptics; Anticonvulsants for grand-mal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/28—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and containing rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
GEAP19974526A 1996-03-14 1997-02-18 Novel Substituted Cyclic Amino Acids as Pharmaceutical Agents GEP20012413B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1343296P 1996-03-14 1996-03-14

Publications (1)

Publication Number Publication Date
GEP20012413B true GEP20012413B (en) 2001-04-25

Family

ID=21759938

Family Applications (1)

Application Number Title Priority Date Filing Date
GEAP19974526A GEP20012413B (en) 1996-03-14 1997-02-18 Novel Substituted Cyclic Amino Acids as Pharmaceutical Agents

Country Status (29)

Country Link
US (1) US6103932A (enExample)
EP (1) EP0888286B1 (enExample)
JP (1) JP2000506861A (enExample)
KR (1) KR100512506B1 (enExample)
AT (1) ATE207878T1 (enExample)
AU (1) AU734173B2 (enExample)
BG (1) BG63662B1 (enExample)
BR (1) BR9708200A (enExample)
CA (1) CA2244912C (enExample)
CZ (1) CZ293759B6 (enExample)
DE (1) DE69707842T2 (enExample)
DK (2) DK0888285T3 (enExample)
EA (1) EA002765B1 (enExample)
EE (1) EE9800309A (enExample)
ES (1) ES2167717T3 (enExample)
GE (1) GEP20012413B (enExample)
HU (1) HU224720B1 (enExample)
IL (1) IL125544A (enExample)
IS (1) IS1990B (enExample)
MX (1) MX9806069A (enExample)
NO (1) NO984205L (enExample)
NZ (1) NZ331143A (enExample)
PL (1) PL185991B1 (enExample)
PT (1) PT888286E (enExample)
SK (1) SK283295B6 (enExample)
TR (1) TR199801807T2 (enExample)
UA (1) UA49011C2 (enExample)
WO (1) WO1997033858A1 (enExample)
ZA (1) ZA972200B (enExample)

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Also Published As

Publication number Publication date
AU734173B2 (en) 2001-06-07
BG63662B1 (bg) 2002-08-30
PL185991B1 (pl) 2003-09-30
EP0888286B1 (en) 2001-10-31
US6103932A (en) 2000-08-15
UA49011C2 (uk) 2002-09-16
KR100512506B1 (ko) 2005-12-21
HUP9902136A3 (en) 2000-03-28
CA2244912C (en) 2005-07-12
NO984205L (no) 1998-09-14
EA199800798A1 (ru) 1999-04-29
IL125544A (en) 2002-03-10
BG102733A (en) 1999-04-30
CA2244912A1 (en) 1997-09-18
DK0888285T3 (da) 2002-04-08
TR199801807T2 (xx) 1998-12-21
DE69707842D1 (de) 2001-12-06
BR9708200A (pt) 1999-07-27
ZA972200B (en) 1997-09-17
JP2000506861A (ja) 2000-06-06
ATE207878T1 (de) 2001-11-15
CZ286398A3 (cs) 1999-03-17
CZ293759B6 (cs) 2004-07-14
HU224720B1 (en) 2006-01-30
EP0888286A1 (en) 1999-01-07
SK283295B6 (sk) 2003-05-02
WO1997033858A1 (en) 1997-09-18
EE9800309A (et) 1999-02-15
HUP9902136A2 (hu) 1999-10-28
DK0888286T3 (da) 2002-02-18
AU2051197A (en) 1997-10-01
MX9806069A (es) 1998-11-30
ES2167717T3 (es) 2002-05-16
IS1990B (is) 2005-02-15
PT888286E (pt) 2002-04-29
EA002765B1 (ru) 2002-08-29
IS4819A (is) 1998-08-10
SK123898A3 (en) 2000-04-10
NO984205D0 (no) 1998-09-11
DE69707842T2 (de) 2002-05-16
NZ331143A (en) 2001-06-29
IL125544A0 (en) 1999-03-12
KR19990087756A (ko) 1999-12-27
PL328816A1 (en) 1999-02-15

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