GB2503148A - Biomarker panels diagnostic methods and test kits for ovarian cancer - Google Patents
Biomarker panels diagnostic methods and test kits for ovarian cancer Download PDFInfo
- Publication number
- GB2503148A GB2503148A GB1316222.7A GB201316222A GB2503148A GB 2503148 A GB2503148 A GB 2503148A GB 201316222 A GB201316222 A GB 201316222A GB 2503148 A GB2503148 A GB 2503148A
- Authority
- GB
- United Kingdom
- Prior art keywords
- ovarian cancer
- test kits
- diagnostic methods
- biomarker panels
- cancer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57449—Specifically defined cancers of ovaries
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
- G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
- G16H50/30—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for calculating health indices; for individual health risk assessment
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161463870P | 2011-02-24 | 2011-02-24 | |
PCT/US2012/024997 WO2012115820A2 (en) | 2011-02-24 | 2012-02-14 | Biomarker panels, diagnostic methods and test kits for ovarian cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
GB201316222D0 GB201316222D0 (en) | 2013-10-30 |
GB2503148A true GB2503148A (en) | 2013-12-18 |
Family
ID=46721396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
GB1316222.7A Withdrawn GB2503148A (en) | 2011-02-24 | 2012-02-14 | Biomarker panels diagnostic methods and test kits for ovarian cancer |
Country Status (9)
Country | Link |
---|---|
US (1) | US20150031561A1 (ko) |
EP (1) | EP2678682A4 (ko) |
KR (1) | KR20140024860A (ko) |
CN (1) | CN103582815A (ko) |
AU (1) | AU2012220896B2 (ko) |
CA (1) | CA2828119A1 (ko) |
DE (1) | DE112012000990B4 (ko) |
GB (1) | GB2503148A (ko) |
WO (1) | WO2012115820A2 (ko) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN104535765A (zh) | 2009-03-12 | 2015-04-22 | 癌症预防和治疗有限公司 | 鉴定、评估、预防以及治疗肺疾病的方法及试剂盒 |
US20150004633A1 (en) * | 2012-02-07 | 2015-01-01 | Quest Diagnostics Investments Incorporated | Assays and methods for the diagnosis of ovarian cancer |
WO2014063743A1 (en) * | 2012-10-25 | 2014-05-01 | Association Pour La Recherche Thérapeutique Anti-Cancéreuse | Methylglyoxal as a marker of cancer |
CA3210220A1 (en) * | 2013-05-10 | 2014-11-13 | Johns Hopkins University | Compositions for ovarian cancer assessment having improved specificity |
CN104422768A (zh) * | 2013-08-30 | 2015-03-18 | 广州瑞博奥生物科技有限公司 | 一种联合检测早期卵巢癌标志物的抗体芯片试剂盒 |
CN113403338A (zh) * | 2014-03-28 | 2021-09-17 | 华盛顿大学商业中心 | 乳腺癌和卵巢癌疫苗 |
EP3125920B1 (en) | 2014-04-04 | 2020-12-23 | Del Mar Pharmaceuticals | Dianhydrogalactitol, diacetyldianhydrogalactitol or dibromodulcitol to treat non-small-cell carcinoma of the lung and ovarian cancer |
CA2981347A1 (en) * | 2015-04-02 | 2016-10-06 | Provista Diagnostics, Inc. | Biomarkers for detection of ovarian cancer |
CN105232060A (zh) * | 2015-08-31 | 2016-01-13 | 陈琼 | 基于独立风险因子组合筛查的预警系统 |
US10823735B2 (en) * | 2015-09-03 | 2020-11-03 | The University Of Hong Kong | Monoclonal antibody for predicting tamoxifen response in breast cancer patients |
MA43342A (fr) * | 2015-09-30 | 2018-08-08 | Medimmune Ltd | Compositions et procédé d'inhibition de cellules souches cancéreuses |
JP6143920B1 (ja) * | 2016-06-20 | 2017-06-07 | 国立研究開発法人国立がん研究センター | 卵巣がんの予後診断マーカーとしてのmmp1遺伝子転写産物と検査法 |
CN107765011A (zh) * | 2016-08-16 | 2018-03-06 | 华明康生物科技(深圳)有限公司 | 早期癌症筛查方法及试剂盒 |
CN107765012B (zh) * | 2016-08-16 | 2020-10-27 | 华明康生物科技(深圳)有限公司 | 早期非小细胞肺癌筛查方法及试剂盒 |
CN107765013B (zh) * | 2016-08-16 | 2021-04-02 | 华明康生物科技(深圳)有限公司 | 早期卵巢癌筛查方法及试剂盒 |
CN107765005B (zh) * | 2016-08-16 | 2021-01-15 | 华明康生物科技(深圳)有限公司 | 早期小细胞肺癌筛查方法及试剂盒 |
CN110709936A (zh) * | 2017-04-04 | 2020-01-17 | 肺癌蛋白质组学有限责任公司 | 用于早期肺癌预后的基于血浆的蛋白质概况分析 |
CN107541499B (zh) * | 2017-07-27 | 2020-04-14 | 山东兴瑞生物科技有限公司 | 一种靶向免疫检测点tnfr2的cik的制备及其应用 |
WO2019210052A1 (en) * | 2018-04-27 | 2019-10-31 | Laboratory Corporation Of America Holdings | Methods and systems for determining the risk of developing ovarian cancer |
WO2019224786A1 (en) * | 2018-05-24 | 2019-11-28 | Alize Pharma Iii Sas | Heparin-binding domain of igfbp-2 in the treatment of metabolic disorders |
CN109342730A (zh) * | 2018-12-07 | 2019-02-15 | 江苏省原子医学研究所 | 同时检测妇科肿瘤标志物her-2和he4的试纸条 |
JPWO2020203478A1 (ko) * | 2019-04-02 | 2020-10-08 | ||
AU2020404453B2 (en) * | 2019-12-20 | 2022-12-08 | Hudson Institute of Medical Research | CXCL10 binding proteins and uses thereof |
KR102316178B1 (ko) * | 2020-04-14 | 2021-10-22 | 서울대학교병원 | 난소암 환자의 암 재발율 또는 생존율 예측용 조성물 |
CN111735949B (zh) * | 2020-07-17 | 2023-07-21 | 北京信诺卫康科技有限公司 | Wnt7a和CA125联合用作早期卵巢癌生物标志物以及试剂盒 |
CN111781364B (zh) * | 2020-08-25 | 2023-07-21 | 北京信诺卫康科技有限公司 | Wnt7a和HE4联合用作早期卵巢癌生物标志物以及试剂盒 |
JP2023550278A (ja) * | 2020-10-30 | 2023-12-01 | エフ. ホフマン-ラ ロシュ アーゲー | 胆管癌のマーカーとしてのtimp1 |
CN112816691B (zh) * | 2021-02-08 | 2024-06-11 | 杭州市妇产科医院 | 一种人卵母细胞质量评价的方法 |
WO2022207685A1 (en) * | 2021-04-01 | 2022-10-06 | F. Hoffmann-La Roche Ag | Psp94 as blood biomarker for the non-invasive diagnosis of endometriosis |
CN116879558B (zh) * | 2023-09-05 | 2023-12-01 | 天津云检医学检验所有限公司 | 卵巢癌诊断标志物、检测试剂及检测试剂盒 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
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US20090075307A1 (en) * | 2006-01-27 | 2009-03-19 | Tripath Imaging, Inc. | Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor |
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US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
US5225539A (en) | 1986-03-27 | 1993-07-06 | Medical Research Council | Recombinant altered antibodies and methods of making altered antibodies |
DE3856559T2 (de) | 1987-05-21 | 2004-04-29 | Micromet Ag | Multifunktionelle Proteine mit vorbestimmter Zielsetzung |
US5132405A (en) | 1987-05-21 | 1992-07-21 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
US5091513A (en) | 1987-05-21 | 1992-02-25 | Creative Biomolecules, Inc. | Biosynthetic antibody binding sites |
US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
US5530101A (en) | 1988-12-28 | 1996-06-25 | Protein Design Labs, Inc. | Humanized immunoglobulins |
US5283173A (en) | 1990-01-24 | 1994-02-01 | The Research Foundation Of State University Of New York | System to detect protein-protein interactions |
WO2001099043A1 (en) | 2000-06-19 | 2001-12-27 | Correlogic Systems, Inc. | Heuristic method of classification |
IL153856A0 (en) | 2000-07-18 | 2003-07-31 | Correlogic Systems Inc | A process for discriminating between biological states based on hidden patterns from biological data |
US7270960B2 (en) * | 2001-08-29 | 2007-09-18 | Pacific Northwest Research Institute | Diagnosis of ovarian carcinomas |
EP1540010B8 (en) * | 2002-08-06 | 2010-07-14 | The Johns Hopkins University | Use of biomarkers for detecting ovarian cancer |
EP1649281A4 (en) | 2003-08-01 | 2007-11-07 | Correlogic Systems Inc | MULTIPLE HIGH RESOLUTION SERUM PROTEOMIC CHARACTERISTICS FOR THE DETECTION OF OVARIAN CANCER |
US20070042405A1 (en) * | 2003-08-15 | 2007-02-22 | University Of Pittsburgh -Of The Commonwealth System Of Higher Education | Enhanced diagnostic multimarker serological profiling |
EP1723428A2 (en) * | 2004-02-19 | 2006-11-22 | Yale University Corporation | Identification of cancer protein biomarkers using proteomic techniques |
WO2005094381A2 (en) | 2004-04-01 | 2005-10-13 | Rules-Based Medicine, Inc. | Universal shotgun assay |
WO2007005426A2 (en) | 2005-06-29 | 2007-01-11 | Rules-Based Medicine, Inc. | Methods and kits for the diagnosis of acute coronary syndrome |
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US8574848B2 (en) * | 2006-09-13 | 2013-11-05 | Oncimmune Ltd. | Immunoassay methods |
WO2008118798A1 (en) * | 2007-03-23 | 2008-10-02 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Multimarker assay for early detection of ovarian cancer |
JP2010532484A (ja) * | 2007-06-29 | 2010-10-07 | コレロジック システムズ,インコーポレイテッド | 卵巣癌のための予測マーカー |
US20100227335A1 (en) * | 2009-03-05 | 2010-09-09 | Becton, Dickinson And Company | Matrix metalloproteinase-7 (mmp-7) monoclonal antibodies and methods for their use in the detection of ovarian cancer |
WO2010148145A1 (en) * | 2009-06-16 | 2010-12-23 | Fred Hutchinson Cancer Research Center | Methods and kits for detecting ovarian cancer from blood |
US20120171694A1 (en) * | 2010-07-30 | 2012-07-05 | Vermillion, Inc. | Predictive markers and biomarker panels for ovarian cancer |
-
2012
- 2012-02-14 EP EP12749936.6A patent/EP2678682A4/en not_active Withdrawn
- 2012-02-14 KR KR1020137025094A patent/KR20140024860A/ko not_active Application Discontinuation
- 2012-02-14 CA CA2828119A patent/CA2828119A1/en not_active Abandoned
- 2012-02-14 GB GB1316222.7A patent/GB2503148A/en not_active Withdrawn
- 2012-02-14 AU AU2012220896A patent/AU2012220896B2/en not_active Ceased
- 2012-02-14 CN CN201280010293.0A patent/CN103582815A/zh active Pending
- 2012-02-14 WO PCT/US2012/024997 patent/WO2012115820A2/en active Application Filing
- 2012-02-14 DE DE112012000990.8T patent/DE112012000990B4/de active Active
-
2013
- 2013-12-06 US US14/099,522 patent/US20150031561A1/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090075307A1 (en) * | 2006-01-27 | 2009-03-19 | Tripath Imaging, Inc. | Methods for identifying patients with an increased likelihood of having ovarian cancer and compositions therefor |
Non-Patent Citations (3)
Title |
---|
DE BRUIJN H. W. et al. Serum and cystic fluid levels of soluble interleukin-2 receptor-alpha in patients with epithelial ovarian tumors are correlated. Tumour Biol., 1998, vol.19, no.3, pp.160-166. See abstract. * |
HURTEAU, J. A. et al. Soluble interleukin-2 receptor alpha is elevated in sera of patients with benign ovarian neoplasms and epithelial ovarian cancer. Cancer, Nov.1 1995, vol.76, no.9 pp.1615-1620. See abstract. * |
SEDLACZEK, P. et al. Comparative analysis of CA125, tissue polypeptide specific antigen, and soluble interleukin-2 receptor alpha levels in sera, cyst, and ascitic fluids from patients with ovarian carcinoma. Cancer, Nov.1 2002, Vol.95, No.9, pp.1886-1893. See the whole document * |
Also Published As
Publication number | Publication date |
---|---|
US20150031561A1 (en) | 2015-01-29 |
EP2678682A4 (en) | 2014-10-01 |
DE112012000990B4 (de) | 2024-06-27 |
DE112012000990T5 (de) | 2014-03-27 |
CA2828119A1 (en) | 2012-08-30 |
WO2012115820A3 (en) | 2013-03-14 |
AU2012220896A1 (en) | 2013-09-05 |
GB201316222D0 (en) | 2013-10-30 |
KR20140024860A (ko) | 2014-03-03 |
WO2012115820A2 (en) | 2012-08-30 |
EP2678682A2 (en) | 2014-01-01 |
AU2012220896B2 (en) | 2016-11-24 |
CN103582815A (zh) | 2014-02-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
WAP | Application withdrawn, taken to be withdrawn or refused ** after publication under section 16(1) |