GB2192185B - Monoclonal antibodies to pseudomonas aeruginosa flagella - Google Patents

Monoclonal antibodies to pseudomonas aeruginosa flagella

Info

Publication number
GB2192185B
GB2192185B GB8715347A GB8715347A GB2192185B GB 2192185 B GB2192185 B GB 2192185B GB 8715347 A GB8715347 A GB 8715347A GB 8715347 A GB8715347 A GB 8715347A GB 2192185 B GB2192185 B GB 2192185B
Authority
GB
United Kingdom
Prior art keywords
monoclonal antibodies
pseudomonas aeruginosa
aeruginosa flagella
flagella
pseudomonas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
GB8715347A
Other languages
English (en)
Other versions
GB8715347D0 (en
GB2192185A (en
Inventor
Mark E Lostrom
Anthony W Siadak
Mae J Rosok
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Genetic Systems Corp
Original Assignee
Genetic Systems Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/946,554 external-priority patent/US4834976A/en
Application filed by Genetic Systems Corp filed Critical Genetic Systems Corp
Publication of GB8715347D0 publication Critical patent/GB8715347D0/en
Publication of GB2192185A publication Critical patent/GB2192185A/en
Application granted granted Critical
Publication of GB2192185B publication Critical patent/GB2192185B/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1214—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biotechnology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
GB8715347A 1986-07-03 1987-06-30 Monoclonal antibodies to pseudomonas aeruginosa flagella Expired - Lifetime GB2192185B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US88198486A 1986-07-03 1986-07-03
US06/946,554 US4834976A (en) 1986-07-03 1986-12-24 Monoclonal antibodies to pseudomonas aeruginosa flagella
US4814387A 1987-05-15 1987-05-15

Publications (3)

Publication Number Publication Date
GB8715347D0 GB8715347D0 (en) 1987-08-05
GB2192185A GB2192185A (en) 1988-01-06
GB2192185B true GB2192185B (en) 1991-01-16

Family

ID=27367280

Family Applications (1)

Application Number Title Priority Date Filing Date
GB8715347A Expired - Lifetime GB2192185B (en) 1986-07-03 1987-06-30 Monoclonal antibodies to pseudomonas aeruginosa flagella

Country Status (19)

Country Link
JP (1) JP2639422B2 (it)
KR (1) KR910002373B1 (it)
AT (1) AT399885B (it)
AU (1) AU615162B2 (it)
BE (1) BE1000743A3 (it)
CH (1) CH677796A5 (it)
DE (1) DE3722098C2 (it)
DK (1) DK172840B1 (it)
ES (1) ES2013321A6 (it)
FR (1) FR2601458B1 (it)
GB (1) GB2192185B (it)
IE (1) IE60888B1 (it)
IL (1) IL83047A (it)
IT (1) IT1221940B (it)
LU (1) LU86938A1 (it)
NL (1) NL194961C (it)
OA (1) OA08629A (it)
PT (1) PT85247B (it)
SE (1) SE506421C2 (it)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4772464A (en) * 1985-08-01 1988-09-20 Miles Laboratories, Inc. Protective antibodies to serotypic determinants of flagellar antigens
NZ218499A (en) * 1985-12-10 1990-04-26 Genetic Systems Corp Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods
DK172840B1 (da) * 1986-07-03 1999-08-09 Genetic Systems Corp Monoklonale antistoffer mod Pseudomonas aeruginosa flagella, farmaceutiske præparater indeholdende sådanne antistoffer og c
CA1341375C (en) * 1988-10-12 2002-07-09 Baxter International Inc. Compositions and methods for the treatment and prevention of gram-negative bacterial infections
JPH02299594A (ja) * 1989-01-30 1990-12-11 Sumitomo Chem Co Ltd ヒトモノクローナル抗体およびその製法
AU5525490A (en) * 1989-04-14 1990-11-16 Biocontrol Systems, Incorporated Process and device for detecting a particular motile organism
DE69131861T2 (de) * 1990-01-18 2000-05-18 Cura Nominees Pty Ltd Glykoalkaloide
CA2751433A1 (en) * 2009-02-04 2010-08-12 Kalobios Pharmaceuticals, Inc. Combination antibiotic and antibody therapy for the treatment of pseudomonas aeruginosa infection
EP2542577A1 (en) * 2010-03-01 2013-01-09 Lostam Biopharmaceuticals Ltd Improved therapeutic antibodies against flagellated pseudomonas aeruginosa

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0211352A2 (en) * 1985-08-01 1987-02-25 Miles Inc. Protective antibodies to serotypic determinants of flagellar antigens

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8422649D0 (en) * 1984-09-07 1984-10-10 Technology Licence Co Ltd Monoclonal antibodies
JP2691708B2 (ja) * 1984-09-26 1997-12-17 住友製薬株式会社 ヒトモノクローナル抗体およびその製法
AU5991786A (en) * 1985-06-06 1987-01-07 Genetic Systems Corporation Protective human monoclonal antibodies to pseudomonas aeruginosa exotoxin a
US4918163A (en) * 1985-09-27 1990-04-17 Pfizer Inc. Monoclonal antibodies specific for lipid-A determinants of gram negative bacteria
ZA868673B (en) * 1985-12-10 1988-07-27 Genetic Systems Corp Monoclonal antibodies cross-reactive and cross-protective against p.aeruginosa serotypes
NZ218499A (en) * 1985-12-10 1990-04-26 Genetic Systems Corp Monoclonal antibodies against pseudomonas aeruginosa, pharmaceutical compositions and detection methods
DK172840B1 (da) * 1986-07-03 1999-08-09 Genetic Systems Corp Monoklonale antistoffer mod Pseudomonas aeruginosa flagella, farmaceutiske præparater indeholdende sådanne antistoffer og c

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0211352A2 (en) * 1985-08-01 1987-02-25 Miles Inc. Protective antibodies to serotypic determinants of flagellar antigens

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Burns (1980) *
Infect. Immu *

Also Published As

Publication number Publication date
GB8715347D0 (en) 1987-08-05
IL83047A (en) 1992-12-01
NL194961C (nl) 2003-09-02
AU615162B2 (en) 1991-09-26
ES2013321A6 (es) 1990-05-01
OA08629A (en) 1988-11-30
FR2601458A1 (fr) 1988-01-15
SE8702734L (sv) 1988-01-04
IL83047A0 (en) 1987-12-31
DK172840B1 (da) 1999-08-09
AT399885B (de) 1995-08-25
JPS63102697A (ja) 1988-05-07
CH677796A5 (it) 1991-06-28
BE1000743A3 (fr) 1989-03-28
AU7495887A (en) 1988-01-07
SE506421C2 (sv) 1997-12-15
SE8702734D0 (sv) 1987-07-02
NL194961B (nl) 2003-05-01
KR880001815A (ko) 1988-04-27
JP2639422B2 (ja) 1997-08-13
DE3722098C2 (de) 1998-06-04
IE871769L (en) 1988-01-03
GB2192185A (en) 1988-01-06
PT85247B (pt) 1990-06-29
KR910002373B1 (ko) 1991-04-20
DE3722098A1 (de) 1988-03-03
NL8701554A (nl) 1988-02-01
IT1221940B (it) 1990-08-31
DK336687A (da) 1988-01-04
LU86938A1 (fr) 1988-02-02
PT85247A (en) 1987-08-01
DK336687D0 (da) 1987-06-30
IE60888B1 (en) 1994-08-24
ATA168387A (de) 1994-12-15
IT8721163A0 (it) 1987-07-02
FR2601458B1 (fr) 1992-08-21

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Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 20070629