GB2018986B - Comperative protein binding assays - Google Patents

Comperative protein binding assays

Info

Publication number
GB2018986B
GB2018986B GB7911845A GB7911845A GB2018986B GB 2018986 B GB2018986 B GB 2018986B GB 7911845 A GB7911845 A GB 7911845A GB 7911845 A GB7911845 A GB 7911845A GB 2018986 B GB2018986 B GB 2018986B
Authority
GB
United Kingdom
Prior art keywords
comperative
binding assays
protein binding
protein
assays
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7911845A
Other languages
English (en)
Other versions
GB2018986A (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syva Co
Original Assignee
Syva Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syva Co filed Critical Syva Co
Publication of GB2018986A publication Critical patent/GB2018986A/en
Application granted granted Critical
Publication of GB2018986B publication Critical patent/GB2018986B/en
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/581Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with enzyme label (including co-enzymes, co-factors, enzyme inhibitors or substrates)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/968High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/805Optical property

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
GB7911845A 1978-04-05 1979-04-04 Comperative protein binding assays Expired GB2018986B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/893,650 US4233402A (en) 1978-04-05 1978-04-05 Reagents and method employing channeling

Publications (2)

Publication Number Publication Date
GB2018986A GB2018986A (en) 1979-10-24
GB2018986B true GB2018986B (en) 1982-12-22

Family

ID=25401860

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7911845A Expired GB2018986B (en) 1978-04-05 1979-04-04 Comperative protein binding assays

Country Status (6)

Country Link
US (1) US4233402A (cg-RX-API-DMAC10.html)
JP (1) JPS54136896A (cg-RX-API-DMAC10.html)
CA (1) CA1110541A (cg-RX-API-DMAC10.html)
DE (1) DE2913550A1 (cg-RX-API-DMAC10.html)
FR (1) FR2434201B1 (cg-RX-API-DMAC10.html)
GB (1) GB2018986B (cg-RX-API-DMAC10.html)

Families Citing this family (289)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2747794A1 (de) * 1977-10-25 1979-05-03 Bosch Gmbh Robert Anzeigeeinheit
US4318707A (en) * 1978-11-24 1982-03-09 Syva Company Macromolecular fluorescent quencher particle in specific receptor assays
US4287300A (en) * 1979-07-26 1981-09-01 Syva Company Charge effects in enzyme immunoassays
IT1123573B (it) * 1979-09-10 1986-04-30 Anic Spa Composizione adatta al controllo di tessuti e/o liquidi biiologici e metodo impiegante la stessa
GB2059421A (en) * 1979-10-03 1981-04-23 Self C H Assay method and reagents therefor
US4446231A (en) * 1979-10-03 1984-05-01 Self Colin H Immunoassay using an amplified cyclic detection system
US4391904A (en) * 1979-12-26 1983-07-05 Syva Company Test strip kits in immunoassays and compositions therein
US4486530A (en) * 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4366241A (en) * 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
JPS5737261A (en) * 1980-08-15 1982-03-01 Otsuka Pharmaceut Co Ltd Measuring method of physiological active substance
US4404278A (en) * 1980-11-24 1983-09-13 Syva Company Methods and compositions for assaying for the production of 1,4-dihydropyridyl
US4378428A (en) * 1981-03-30 1983-03-29 Baker Instruments Corporation Method for carrying out non-isotopic immunoassays, labeled analytes and kits for use in such assays
FR2503870A1 (fr) * 1981-04-10 1982-10-15 Fella Christian Procede de detection de la presence d'antigenes pneumocoque xiv dans un prelevement de cellules humaines, et produits pour mettre en oeuvre ce procede
US4442218A (en) * 1981-05-27 1984-04-10 Corning Glass Works Method of measuring degree of partitioning
JPS585659A (ja) * 1981-06-24 1983-01-13 ハイブリテツク インコ−ポレ−テツド 単クロ−ン性抗体を使用する免疫学的、抑制試験
CA1185177A (en) * 1981-07-17 1985-04-09 Larry E. Morrison Non-radiative energy transfer immunochemical technique
CA1209889A (en) * 1981-09-18 1986-08-19 Litai Weng Homogeneous assay on a non-porous surface
US4629690A (en) * 1981-09-18 1986-12-16 Syntex (U.S.A.) Inc. Homogeneous enzyme specific binding assay on non-porous surface
US4463090A (en) * 1981-09-30 1984-07-31 Harris Curtis C Cascade amplification enzyme immunoassay
US4562148A (en) * 1981-11-06 1985-12-31 Miles Laboratories, Inc. Analytical element and method for preventing reagent migration
US5292668A (en) * 1981-12-21 1994-03-08 Boston Biomedical Research Institute, Inc. Bispecific antibody determinants
EP0091837B1 (en) * 1982-04-14 1989-07-26 Radiometer Corporate Development Limited Microbiological test processes and apparatus
US4663278A (en) * 1982-04-30 1987-05-05 Syva Company Agglutination dependent enzyme channeling immunoassay
US4435504A (en) * 1982-07-15 1984-03-06 Syva Company Immunochromatographic assay with support having bound "MIP" and second enzyme
US5512329A (en) * 1982-09-29 1996-04-30 Bsi Corporation Substrate surface preparation
US4614712A (en) * 1983-02-25 1986-09-30 The Upjohn Company Immunoassays with luciferase labeled ligands or receptors
US4687735A (en) * 1983-03-14 1987-08-18 Syntex (U.S.A.) Inc. Enzymatic poly-reactant channeling binding assay
US4536479A (en) * 1983-03-22 1985-08-20 E. I. Du Pont De Nemours And Company Use of anti-idiotype antibodies in immunoassays
US4550075A (en) * 1983-06-22 1985-10-29 Kallestad Laboratories, Inc. Method for ligand determination utilizing an immunoassay monitorable by biotin-containing enzymes, and compositions therefor
USRE34405E (en) * 1983-08-01 1993-10-12 Abbott Laboratories Determination of analytes in particle-containing medium
JPS6071958A (ja) * 1983-09-28 1985-04-23 Akio Tsuji 酵素免疫測定法
ZA849593B (en) * 1983-12-12 1985-07-31 Miles Lab Hybridization assay employing labeled pairs of hybrid binding reagents
EP0152254A3 (en) * 1984-02-06 1986-08-06 E.I. Du Pont De Nemours And Company Chromogenic support immunoassay utilizing labeled complement components
US4645828A (en) 1984-03-23 1987-02-24 Oncogen Platelet related growth regulator
DE3583278D1 (de) * 1984-04-23 1991-07-25 Boston Biomed Res Inst Doppelspezifische antikoerper-determinanten.
AU560779B2 (en) * 1985-01-24 1987-04-16 Quidel Assay for drugs of abuse
IE64785B1 (en) 1985-04-08 1995-09-06 Genetic Systems Corp Expression of immunologically reactive viral proteins
EP0245477A4 (en) * 1985-11-19 1989-08-09 Univ Johns Hopkins Capacitive sensor for chemical analysis and measurement.
JPH0799369B2 (ja) * 1985-11-25 1995-10-25 日本ケミカルリサーチ株式会社 上皮細胞増殖因子の酵素免疫測定法
US4937188A (en) * 1986-04-15 1990-06-26 Northeastern University Enzyme activity amplification method for increasing assay sensitivity
US5190864A (en) * 1986-04-15 1993-03-02 Northeastern University Enzyme amplification by using free enzyme to release enzyme from an immobilized enzyme material
US4777128A (en) * 1986-05-27 1988-10-11 Ethigen Corporation Fluorescence immunoassay involving energy transfer between two fluorophores
US4888276A (en) * 1986-06-26 1989-12-19 Minnesota Mining And Manufacturing Company Method and composition for the diagnosis of Lyme disease
US4835099A (en) * 1986-11-20 1989-05-30 Becton, Dickinson And Company Signal enhancement in immunoassay by modulation of enzymatic catalysis
US5494793A (en) * 1986-12-15 1996-02-27 British Technology Group Usa Inc. Monomeric phthalocyanine reagents
US5346670A (en) * 1986-12-24 1994-09-13 British Technology Group U.S.A. Inc. Phthalocyanine and tetrabenztriazaporphyrin reagents
US5082627A (en) * 1987-05-01 1992-01-21 Biotronic Systems Corporation Three dimensional binding site array for interfering with an electrical field
EP0310361A3 (en) * 1987-09-30 1989-05-24 Beckman Instruments, Inc. Tridentate conjugate and method of use thereof
US4859612A (en) * 1987-10-07 1989-08-22 Hygeia Sciences, Inc. Metal sol capture immunoassay procedure, kit for use therewith and captured metal containing composite
US5256372A (en) * 1987-11-06 1993-10-26 Idexx Corporation Dipstick test device including a removable filter assembly
US5202267A (en) * 1988-04-04 1993-04-13 Hygeia Sciences, Inc. Sol capture immunoassay kit and procedure
US5374524A (en) * 1988-05-10 1994-12-20 E. I. Du Pont De Nemours And Company Solution sandwich hybridization, capture and detection of amplified nucleic acids
US5137804A (en) * 1988-05-10 1992-08-11 E. I. Du Pont De Nemours And Company Assay device and immunoassay
US5039607A (en) * 1988-05-17 1991-08-13 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5334513A (en) * 1988-05-17 1994-08-02 Syntex (U.S.A.) Inc. Method for immunochromatographic analysis
US5028535A (en) * 1989-01-10 1991-07-02 Biosite Diagnostics, Inc. Threshold ligand-receptor assay
US5939272A (en) * 1989-01-10 1999-08-17 Biosite Diagnostics Incorporated Non-competitive threshold ligand-receptor assays
US5196306A (en) * 1989-03-29 1993-03-23 E. I. Du Pont De Nemours And Company Method for the detection or quantitation of an analyte using an analyte dependent enzyme activation system
US5532138A (en) * 1990-04-26 1996-07-02 Behringwerke Ag Method and kits for determining peroxidatively active catalysts
WO1992005282A1 (en) * 1990-09-14 1992-04-02 Biosite Diagnostics, Inc. Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays
US5143852A (en) 1990-09-14 1992-09-01 Biosite Diagnostics, Inc. Antibodies to ligand analogues and their utility in ligand-receptor assays
DE4103167A1 (de) * 1991-02-02 1992-08-06 Boehringer Mannheim Gmbh Diphenylmethanderivate, verfahren zu deren herstellung und ihre verwendung zur verdraengung von jodthyroninen von diesen bindenden proteinen
US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5340716A (en) * 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
US5578498A (en) * 1991-05-22 1996-11-26 Behringwerke Ag Metal chelate containing compositions for use in chemiluminescent assays
US6168956B1 (en) 1991-05-29 2001-01-02 Beckman Coulter, Inc. Multiple component chromatographic assay device
US5998220A (en) * 1991-05-29 1999-12-07 Beckman Coulter, Inc. Opposable-element assay devices, kits, and methods employing them
US5877028A (en) * 1991-05-29 1999-03-02 Smithkline Diagnostics, Inc. Immunochromatographic assay device
CA2074752A1 (en) * 1991-07-29 1993-01-30 Tadakazu Yamauchi Process and device for specific binding assay
EP0561626B1 (en) * 1992-03-17 1998-08-12 Unitika Ltd. A method for enzymatic analysis and reagent therefor
US5332662A (en) * 1992-07-31 1994-07-26 Syntex (U.S.A.) Inc. Methods for determining peroxidatively active substances
WO1994003812A1 (en) * 1992-07-31 1994-02-17 Syntex (U.S.A.) Inc. Photoactivatable chemiluminescent matrices
US5354692A (en) * 1992-09-08 1994-10-11 Pacific Biotech, Inc. Analyte detection device including a hydrophobic barrier for improved fluid flow
US6953573B1 (en) * 1993-03-17 2005-10-11 University Of Washington Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated
US5801005A (en) * 1993-03-17 1998-09-01 University Of Washington Immune reactivity to HER-2/neu protein for diagnosis of malignancies in which the HER-2/neu oncogene is associated
US5869445A (en) * 1993-03-17 1999-02-09 University Of Washington Methods for eliciting or enhancing reactivity to HER-2/neu protein
AU679008B2 (en) * 1993-05-06 1997-06-19 Chiron Diagnostics Corporation Mixed luminescent conjugate test assays
DE69417242T2 (de) * 1993-09-03 1999-07-08 Behringwerke AG, 35041 Marburg Fluoreszenz-sauerstoffkanalisation-immunteste
US7635597B2 (en) 1995-08-09 2009-12-22 Bayer Healthcare Llc Dry reagent particle assay and device having multiple test zones and method therefor
US6942862B2 (en) * 1996-04-01 2005-09-13 University Of Washington Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins
WO1997041442A1 (en) * 1996-05-01 1997-11-06 Behringwerke Aktiengesellschaft Chemiluminescent compositions and their use in the detection of hydrogen peroxide
US5968839A (en) * 1996-05-13 1999-10-19 Metrika, Inc. Method and device producing a predetermined distribution of detectable change in assays
US6331275B1 (en) 1996-07-08 2001-12-18 Burstein Technologies, Inc. Spatially addressable, cleavable reflective signal elements, assay device and method
US6342349B1 (en) 1996-07-08 2002-01-29 Burstein Technologies, Inc. Optical disk-based assay devices and methods
IL151635A0 (en) 1996-07-08 2003-04-10 Burstein Technologies Inc Cleavable signal element device for diagnostic applications and assay method
EP0880705B1 (en) 1996-07-18 2003-06-18 Dade Behring Marburg GmbH Reagents for assays for mycophenolic acid
WO1998003876A1 (en) * 1996-07-18 1998-01-29 Behringwerke Aktiengesellschaft Reagents for assays for mycophenolic acid
US5945345A (en) * 1996-08-27 1999-08-31 Metrika, Inc. Device for preventing assay interference using silver or lead to remove the interferant
GB9622524D0 (en) * 1996-10-29 1997-01-08 London Biotechnology Ltd Enzyme labels for assays
US5929049A (en) 1997-08-08 1999-07-27 Dade Behring Marburg Gmbh Polysaccharide conjugates of biomolecules
US6007992A (en) * 1997-11-10 1999-12-28 Gilead Sciences, Inc. Pyrimidine derivatives for labeled binding partners
US6028183A (en) * 1997-11-07 2000-02-22 Gilead Sciences, Inc. Pyrimidine derivatives and oligonucleotides containing same
US6153442A (en) * 1998-05-20 2000-11-28 Dade Behring Inc. Reagents and methods for specific binding assays
EP1097378A2 (en) * 1998-07-21 2001-05-09 Burstein Laboratories Inc. Optical disc-based assay devices and methods
DE69836493T2 (de) 1998-07-22 2007-09-06 Syntron Bioresearch, Inc., Carlsbad Vorrichtung zur bestimmung von mehreren analyten
AU6206800A (en) 1999-07-06 2001-01-22 Surromed, Inc. Bridged fluorescent dyes, their preparation and their use in assays
ES2629683T3 (es) 1999-11-30 2017-08-14 Mayo Foundation For Medical Education And Research B7-H1, una nueva molécula inmunorreguladora
US6891030B2 (en) 2000-07-27 2005-05-10 Mayo Foundation For Medical Education And Research T-cell immunoregulatory molecule
WO2002043866A2 (en) * 2000-12-01 2002-06-06 Burstein Technologies, Inc. Apparatus and methods for separating components of particulate suspension
WO2003087827A2 (en) 2001-04-11 2003-10-23 Burstein Technologies, Inc. Multi-parameter assays including analysis discs and methods relating thereto
US20030230383A1 (en) * 2001-07-24 2003-12-18 Glenn Sasaki Method and apparatus for bonded fluidic circuit for optical bio-disc
US20030129665A1 (en) * 2001-08-30 2003-07-10 Selvan Gowri Pyapali Methods for qualitative and quantitative analysis of cells and related optical bio-disc systems
WO2003021222A2 (en) * 2001-08-31 2003-03-13 Burstein Technologies, Inc. Capture layer assemblies for cellular assays including related optical analysis discs and methods
US20030113925A1 (en) * 2001-09-07 2003-06-19 Gordon John Francis Nuclear morphology based identification and quantification of white blood cell types using optical bio-disc systems
EP1448992A4 (en) * 2001-11-20 2005-11-02 Burstein Technologies Inc OPTICAL BIODISTICS AND FLUIDIC CIRCUITS FOR CELL ANALYSIS AND CORRESPONDING METHODS
US6696254B2 (en) 2001-11-21 2004-02-24 Kimberly-Clark Worldwide, Inc. Detection and identification of enteric bacteria
WO2003050537A1 (en) * 2001-12-12 2003-06-19 Proteome Systems Intellectual Property Pty Ltd Diagnostic testing process
KR100567432B1 (ko) * 2001-12-28 2006-04-04 아크레이 가부시키가이샤 비색분석방법 및 이에 사용하는 시약
WO2003057905A1 (en) * 2001-12-28 2003-07-17 Arkray, Inc. Method of colorimetry and reagent for use therein
US20050221048A1 (en) * 2002-01-31 2005-10-06 James Rodney Norton Manufacturing processes for making optical analysis discs including successive patterning operations and optical discs thereby manufactured
US20040241381A1 (en) * 2002-01-31 2004-12-02 Chen Yihfar Microfluidic structures with circumferential grooves for bonding adhesives and related optical analysis discs
US20050176059A1 (en) * 2002-01-31 2005-08-11 Pal Andrew A. Bio-safe dispenser and optical analysis disc assembly
US20050023765A1 (en) * 2002-01-31 2005-02-03 Coombs James Howard Bio-safety features for optical analysis disc and disc system including same
CA2704273C (en) 2002-02-21 2016-01-05 Institute Of Virology Mn/ca ix-antibody binding specifically to non-immunodominant epitope of mn/ca ix and uses thereof
AU2003230925A1 (en) * 2002-04-16 2003-11-03 The Regents Of The University Of California Methods or renal cell carcinoma prognosis and treatment selection with carbonic anhydrase ix
US7462458B2 (en) * 2002-05-15 2008-12-09 Mayo Foundation For Medical Education And Research Methods of detecting ovarian neoplasia
US20060110730A1 (en) * 2002-05-20 2006-05-25 Bose Himangshu S Methods and compositions for regulation and manipulation of steroidogenesis
CA2486619A1 (en) * 2002-05-21 2003-12-04 Mayo Foundation For Medical Education And Research Methods and materials for treating inflammatory conditions
US20050221349A1 (en) * 2002-05-30 2005-10-06 Stuart Wilson Methods of detecting target molecules and molecular interactions
EP1599730A2 (en) * 2003-03-03 2005-11-30 Kouyama, Yoshihisa Methods and apparatus for use in detection and quantitation of various cell types and use of optical bio-disc for performing same
WO2004095034A1 (en) * 2003-04-23 2004-11-04 Nagaoka & Co., Ltd. Optical bio-discs including spiral fluidic circuits for performing assays
EP1656203A2 (en) * 2003-06-19 2006-05-17 Nagaoka & Co., Ltd. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US7390464B2 (en) * 2003-06-19 2008-06-24 Burstein Technologies, Inc. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
ATE485303T1 (de) 2003-06-20 2010-11-15 Mayo Foundation Isoformen von gehirn-natriuretischem peptid
WO2005001429A2 (en) * 2003-06-27 2005-01-06 Nagaoka & Co., Ltd. Fluidic circuits, methods and apparatus for use of whole blood samples in colorimetric assays
CA2542984A1 (en) * 2003-07-07 2005-01-27 David H. Wagner Methods for predicting development of auto-immune diseases and treatment of same
US20070274863A1 (en) * 2003-07-25 2007-11-29 Horacio Kido Fluidic circuits for sample preparation including bio-discs and methods relating thereto
DK1682177T3 (da) 2003-11-04 2010-11-01 Novartis Vaccines & Diagnostic Anvendelse af antagonist-anti-CD40-antistoffer til behandling af kronisk lymfocytisk leukæmi
ATE474599T1 (de) 2003-11-04 2010-08-15 Novartis Vaccines & Diagnostic Verwendung von antagonisten-anti-cd40- monoklonalen antikörpern zur behandlung von multiplem myelom
ATE476448T1 (de) 2003-11-04 2010-08-15 Novartis Vaccines & Diagnostic Verwendung von antagonist-anti-cd40-antikörpern zur behandlung von autoimmunkrankheiten und entzündlichen erkrankungen und organtransplantat- abstossung
WO2005044305A2 (en) 2003-11-04 2005-05-19 Chiron Corporation Methods of therapy for solid tumors expressing the cd40 cell-surface antigen
JP3615752B1 (ja) 2003-11-18 2005-02-02 淳 高橋 細径樹脂捩じりブラシ
US6991911B2 (en) 2003-12-15 2006-01-31 Dade Behring Inc. Assay for entactogens
US7022492B2 (en) 2003-12-15 2006-04-04 Dade Behring Inc. Ecstasy haptens and immunogens
US7150995B2 (en) 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
JP5303146B2 (ja) 2004-10-06 2013-10-02 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ B7−h1ならびに癌の診断、予後診断および処置の方法
EP1809765A2 (en) * 2004-11-04 2007-07-25 Roche Diagnostics GmbH Classification of acute myeloid leukemia
US7842794B2 (en) 2004-12-17 2010-11-30 Roche Molecular Systems, Inc. Reagents and methods for detecting Neisseria gonorrhoeae
US8323977B2 (en) 2005-01-28 2012-12-04 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Portland State University Method for determining redox activity and screening compounds based on redox activity
US8017401B2 (en) * 2005-01-28 2011-09-13 State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Portland State University Method for determining redox activity and screening compounds based on redox activity
US20060188997A1 (en) * 2005-01-28 2006-08-24 Portland State University Detection of superoxide ions
EP1848981A4 (en) * 2005-02-09 2012-01-18 Oregon State METHOD FOR DETERMINING REDOX ACTIVITY AND SCREENING COMPOUNDS BASED ON REDOX ACTIVITY
US20060182722A1 (en) * 2005-02-11 2006-08-17 Hering Bernhard J Methods and materials for isolating isogenic islet cells
DE602006002809D1 (de) * 2005-02-16 2008-10-30 Dana Farber Cancer Inst Inc Verfahren zur erkennung eines ovarialkarzinoms
US7189582B2 (en) 2005-04-27 2007-03-13 Dade Behring Inc. Compositions and methods for detection of sirolimus
WO2006125021A2 (en) * 2005-05-16 2006-11-23 Dana Farber Cancer Institute, Inc. Fibrinogen alpha and hemoglobin polypeptides as cancer markers
HRP20130852T1 (en) 2005-05-18 2013-10-25 Novartis Ag Methods for diagnosis and treatment of diseases having an autoimmune and/or inflammatory component
KR101514463B1 (ko) 2005-06-08 2015-04-28 다나-파버 캔서 인스티튜트 인크. 예정 세포사 1(pd-1) 경로를 억제함으로써 지속 감염 및 암을 치료하기 위한 방법 및 조성물
US7695975B2 (en) 2005-06-23 2010-04-13 Siemens Healthcare Diagnostics Inc. Detection of adulterated samples
US20070037174A1 (en) * 2005-08-12 2007-02-15 Rampal Jang B Chemiluminescent generated fluorescent labeling
US20070218519A1 (en) * 2005-10-11 2007-09-20 Tethys Bioscience, Inc. Diabetes-associated markers and methods of use thereof
US8119358B2 (en) 2005-10-11 2012-02-21 Tethys Bioscience, Inc. Diabetes-related biomarkers and methods of use thereof
EP1952158A2 (en) * 2005-11-12 2008-08-06 Platform Diagnostics Limited Agglutination assay
US9121853B2 (en) * 2006-03-20 2015-09-01 Mayo Foundation For Medical Education And Research B7-H4 expression on tumor vasculature
KR101317235B1 (ko) 2006-04-21 2013-10-15 조마 테크놀로지 리미티드 길항제 항-cd40 항체 제약 조성물
US7799534B2 (en) 2006-05-09 2010-09-21 Beckman Coulter, Inc. Nonseparation assay methods
US7732153B2 (en) 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
CA2659082A1 (en) 2006-06-07 2007-12-21 Tethys Bioscience, Inc. Markers associated with arteriovascular events and methods of use thereof
MX2009001459A (es) 2006-08-08 2009-02-19 Mayo Foundation Polipeptidos diureticos y natriureticos.
US20100267052A1 (en) * 2006-09-01 2010-10-21 American Type Culture Collection Compositions and methods for diagnosis and treatment of type 2 diabetes
US20090203602A1 (en) * 2006-09-01 2009-08-13 Cohava Gelber Compositions and methods for diagnosis and treatment of type 2 diabetes
US20080300170A1 (en) * 2006-09-01 2008-12-04 Cohava Gelber Compositions and methods for diagnosis and treatment for type 2 diabetes
US7951776B2 (en) * 2006-09-01 2011-05-31 American Type Culture Collection Methods for treatment of type 1 diabetes
BRPI0716228A2 (pt) 2006-09-08 2013-10-15 Mayo Foundation Polipeptídeos aquaréticos e natriuréticos carecendo de atividade vasodilatadora
BRPI0717416A2 (pt) 2006-09-21 2013-11-12 Prometheus Lab Inc Método para realizar um imunoensaio complexo de alta produtividade, e, arranjo
US7989173B2 (en) 2006-12-27 2011-08-02 The Johns Hopkins University Detection and diagnosis of inflammatory disorders
GB0700133D0 (en) 2007-01-04 2007-02-14 Humabs Llc Human cytomegalovirus neutralising antibodies and use thereof
CA2675583A1 (en) * 2007-01-16 2008-07-24 Wyeth Inflammation treatment, detection and monitoring via trem-1
DK2147315T3 (da) 2007-04-18 2013-09-23 Tethys Bioscience Inc Diabetesrelaterede biomarkører og fremgangsmåder til anvendelse deraf
EP2544006A1 (en) 2007-06-04 2013-01-09 Diagnoplex Biomarker combinations for colorectal cancer
NZ582618A (en) * 2007-07-13 2012-07-27 Prometheus Lab Inc Drug selection for lung cancer therapy using antibody-based arrays
ES2472791T3 (es) 2007-07-20 2014-07-03 Mayo Foundation For Medical Education And Research Polip�ptidos natriur�ticos
US7790401B2 (en) 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
WO2009036448A2 (en) * 2007-09-15 2009-03-19 Mayo Foundation For Medical Education And Research Natriuretic peptide receptor-c agonists
US20100240070A1 (en) * 2007-11-07 2010-09-23 Beckman Coulter, Inc. Nonseparation Assay Methods Using Peroxide Generating Enzymes
US7910378B2 (en) 2007-12-14 2011-03-22 Siemens Healthcare Diagnostics Inc. Methods for detection of hydrophobic drugs
ES2398618T3 (es) 2008-02-25 2013-03-20 Nestec S.A. Selección de fármacos para terapia del cáncer de mama utilizando matrices de anticuerpos
CA2728674A1 (en) * 2008-06-26 2009-12-30 Dana-Farber Cancer Institute, Inc. Signatures and determinants associated with metastasis methods of use thereof
DK2307447T3 (da) 2008-07-02 2016-06-20 Mayo Foundation Natriuretiske polypeptider med unikke farmakologiske profiler
WO2010006048A2 (en) 2008-07-08 2010-01-14 Source Precision Medicine, Inc. Gene expression profiling for predicting the survivability of prostate cancer subjects
JP5422649B2 (ja) 2008-07-16 2014-02-19 インスティテュート フォー リサーチ イン バイオメディシン ヒトサイトメガロウイルス中和抗体およびその使用
CN102143974B (zh) 2008-07-16 2015-03-25 生命医学研究学会 人巨细胞病毒中和抗体及其用途
WO2010009438A1 (en) 2008-07-17 2010-01-21 Andreas Pfuetzner Biomarkers for insulin resistance and beta-cell dysfunction
WO2010007526A1 (en) 2008-07-17 2010-01-21 Andreas Pfuetzner Biomarkers for cardiodiabetes
US9340603B2 (en) * 2008-07-25 2016-05-17 Institute For Research In Biomedicine Neutralizing anti-influenza A virus antibodies and uses thereof
US8871207B2 (en) 2008-07-25 2014-10-28 Humabs, LLC Neutralizing anti-influenza A virus antibodies and uses thereof
US8642550B2 (en) 2008-10-24 2014-02-04 Mayo Foundation For Medical Education And Research Chimeric natriuretic peptides without hypotensive inducing capability
WO2010065850A2 (en) * 2008-12-04 2010-06-10 University Of Massachusetts Interleukin 6 and tumor necrosis factor alpha as biomarkers of jnk inhibition
EP2374007A2 (en) 2008-12-04 2011-10-12 IKFE GmbH Biomarkers for atherosclerosis
WO2010067207A1 (en) 2008-12-11 2010-06-17 Ikfe Gmbh Biomarkers for insulin sensitizer drug response
US8455438B2 (en) 2008-12-29 2013-06-04 Mayo Foundation For Medical Education And Research Natriuretic polypeptides for reducing or preventing restenosis
EP2382467A1 (en) 2008-12-30 2011-11-02 IKFE GmbH Biomarkers for adipose tissue activity
US8455263B2 (en) 2008-12-30 2013-06-04 Jin Po Lee Quantitative analyte assay device and method
EP2382475A2 (en) 2009-01-07 2011-11-02 IKFE GmbH Biomarkers for appetite regulation
EP2393517A1 (en) 2009-02-04 2011-12-14 Massachusetts Institute of Technology Compositions and uses to govern cancer cell growth
US20120108514A1 (en) 2009-07-09 2012-05-03 University Of Iowa Research Foundation Long acting atrial natriuretic peptide (la-anp) and methods for use thereof
ES2627909T3 (es) 2009-07-15 2017-08-01 Diatech Holdings, Inc. Selección de fármacos para el tratamiento del cáncer gástrico usando matrices basadas en anticuercuerpos
CN102741279A (zh) 2009-08-31 2012-10-17 艾普利穆恩公司 B7-h4融合蛋白和其使用方法
AU2010306593B2 (en) 2009-10-15 2015-09-10 Crescendo Bioscience, Inc. Biomarkers and methods for measuring and monitoring inflammatory disease activity
WO2011059721A1 (en) 2009-10-29 2011-05-19 Tethys Bioscience, Inc. Protein and lipid biomarkers providing consistent improvement to the prediction of type 2 diabetes
WO2011059720A2 (en) 2009-10-29 2011-05-19 Tethys Bioscience, Inc. Method for determining risk of diabetes
WO2011058367A2 (en) 2009-11-13 2011-05-19 Astrazeneca Ab Diagnostic test for predicting responsiveness to treatment with poly(adp-ribose) polymerase (parp) inhibitor
WO2011063198A2 (en) 2009-11-20 2011-05-26 St. Jude Children's Research Hospital Methods and compositions for modulating the activity of the interleukin-35 receptor complex
EP2561363B1 (en) 2010-04-21 2021-07-14 Memed Diagnostics, Ltd. Signatures and determinants for distinguishing between a bacterial and viral infection and methods of use thereof
US8329424B2 (en) 2010-06-25 2012-12-11 Siemens Healthcare Diagnostics Reduction in false results in assay measurements
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
US10088490B2 (en) 2010-08-20 2018-10-02 Siemens Healthcare Diagnostics Inc. Assay for analytes using multiple receptors
US20140308242A1 (en) 2010-10-21 2014-10-16 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
WO2012075111A1 (en) 2010-11-30 2012-06-07 Novartis Ag Uses of anti-cd40 antibodies in combination therapy for b cell-related cancers
US9719995B2 (en) 2011-02-03 2017-08-01 Pierian Holdings, Inc. Drug selection for colorectal cancer therapy using receptor tyrosine kinase profiling
DK3418300T3 (da) 2011-07-18 2020-12-07 Inst Res Biomedicine Neutralisering af anti-influenza-a-virusantistoffer og anvendelser deraf
EP2742352B1 (en) 2011-08-12 2018-02-28 Siemens Healthcare Diagnostics Inc. Detection of sex steroids
EP2751136B1 (en) 2011-08-30 2017-10-18 Mayo Foundation For Medical Education And Research Natriuretic polypeptides
ES2553456T3 (es) 2011-09-02 2015-12-09 Nestec S.A. Perfilado de proteínas de ruta de señal para determinar una eficacia terapéutica
WO2013071066A1 (en) 2011-11-11 2013-05-16 The Broad Institute, Inc. Signatures associated with the response to cancer therapy
US9611305B2 (en) 2012-01-06 2017-04-04 Mayo Foundation For Medical Education And Research Treating cardiovascular or renal diseases
US8771964B2 (en) 2012-02-02 2014-07-08 Siemens Healthcare Diagnostics Inc. Compositions and methods for detection of methadone metabolite
CN108802385B (zh) 2012-02-09 2022-02-08 米密德诊断学有限公司 用于诊断感染的标记和决定因素和其使用方法
AU2013237087B2 (en) 2012-03-20 2017-07-20 Humabs Biomed Sa Antibodies that neutralize RSV, MPV and PVM and uses thereof
US20150072880A1 (en) 2012-05-09 2015-03-12 David A. Calderwood Rapid detection of analytes in liquid samples
CN104640856B (zh) 2012-05-11 2017-09-15 复位治疗公司 作为隐花色素调节剂的含有咔唑的磺酰胺类
WO2014004444A1 (en) 2012-06-27 2014-01-03 Siemens Healthcare Diagnostics Inc. Compositions and methods for liquid mixing assessment
WO2014015217A1 (en) 2012-07-19 2014-01-23 Vertex Pharmaceuticals Incorporated Biomarkers for hcv infected patients
EP2885423B1 (en) 2012-08-15 2017-09-27 The Procter and Gamble Company Systems for identifying and evaluating skin-active agents effective for treating an array of skin disorders
US10288626B2 (en) 2012-09-14 2019-05-14 University Of Kentucky Research Foundation Secreted tumor-associated cytochrome as a blood-based biomarker for cancer
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
US9121859B2 (en) 2012-12-04 2015-09-01 Siemens Healthcare Diagnostics Inc. Compounds and methods for determination of FKBP-binding immunosuppressant drugs
EP2948471A4 (en) 2013-01-24 2016-08-10 Mayo Foundation METHOD AND MATERIALS FOR DETECTING POSITIVE FRONTOTEMPORAL PAPER DEGENERATION BY C9ORF72 HEXANUCLEOTIDE REPEAT EXPANSION OR AMYOTROPHATE LATERAL SCLEROSIS BY C9ORF72 HEXANUCLEOTIDE REPEAT EXPANSION
US9302005B2 (en) 2013-03-14 2016-04-05 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
US20140308751A1 (en) 2013-04-12 2014-10-16 Siemens Healthcare Diagnostics Inc. Assays for Analyte Homologs
CN105247069A (zh) * 2013-06-04 2016-01-13 豪夫迈·罗氏有限公司 用于fret的新化合物及与其相关的方法
EP3470081A1 (en) 2013-10-01 2019-04-17 Mayo Foundation for Medical Education and Research Methods for treating cancer in patients with elevated levels of bim
CN113667012B (zh) 2013-10-02 2024-07-12 免疫医疗有限责任公司 中和抗甲型流感抗体及其用途
KR20160058960A (ko) 2013-10-04 2016-05-25 압토스 바이오사이언시스 인코포레이티드 암을 치료하기 위한 조성물과 방법
WO2015061260A1 (en) 2013-10-24 2015-04-30 Siemens Healthcare Diagnostics Inc. Assays for macromolecular analytes
JP6559135B2 (ja) 2013-12-13 2019-08-14 シーメンス・ヘルスケア・ダイアグノスティックス・インコーポレーテッドSiemens Healthcare Diagnostics Inc. 非凝集検定における前処理剤
WO2015095426A1 (en) 2013-12-18 2015-06-25 Siemens Healthcare Diagnostics Inc. Detection of endothelial disease
SG10201808565QA (en) 2014-03-31 2018-11-29 Debiopharm Int Sa Fgfr fusions
CA2943821A1 (en) 2014-04-02 2015-10-08 Crescendo Bioscience Biomarkers and methods for measuring and monitoring juvenile idiopathic arthritis activity
TWI690521B (zh) 2014-04-07 2020-04-11 美商同步製藥公司 作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
US9176113B1 (en) 2014-04-11 2015-11-03 Synapdx Corporation Methods and systems for determining autism spectrum disorder risk
US10302653B2 (en) 2014-05-22 2019-05-28 Mayo Foundation For Medical Education And Research Distinguishing antagonistic and agonistic anti B7-H1 antibodies
JP2017523437A (ja) 2014-06-10 2017-08-17 クレッシェンド バイオサイエンス インコーポレイテッド 体軸性脊椎関節炎の疾患活動性を測定およびモニタリングするためのバイオマーカーおよび方法
KR20170016009A (ko) 2014-06-27 2017-02-10 지멘스 헬쓰케어 다이아그노스틱스 인크. 비타민 d 검정에서 비타민 d 에피머에 특이적인 결합 파트너
AU2015280292B2 (en) 2014-06-27 2019-08-01 Siemens Healthcare Diagnostics Inc. Binding partners specific for vitamin D epimers
AU2015289805B2 (en) 2014-07-15 2020-06-25 Humabs Biomed Sa Neutralizing anti-influenza B antibodies and uses thereof
US10517875B2 (en) 2014-07-23 2019-12-31 Mayo Foundation for Medical Engineering and Research Targeting DNA-PKcs and B7-H1 to treat cancer
EP3180621B1 (en) 2014-08-14 2020-04-01 Memed Diagnostics Ltd. Computational analysis of biological data using manifold and a hyperplane
WO2016055950A1 (en) 2014-10-08 2016-04-14 Novartis Ag Combination of human cytomegalovirus neutralizing antibodies
WO2016075546A2 (en) 2014-11-14 2016-05-19 Antonio Lanzavecchia Antibodies that neutralize ebola virus and uses thereof
CN107428819B (zh) 2014-11-18 2022-03-15 胡默波斯生物医学公司 强力地中和狂犬病毒和其它狂犬病毒属病毒的抗体和其用途
EP3230740B1 (en) 2014-12-11 2025-05-21 Memed Diagnostics Ltd. Marker combinations for diagnosing infections and methods of use thereof
EP3960761A1 (en) 2015-06-01 2022-03-02 MedImmune, LLC Neutralizing anti-influenza binding molecules and uses thereof
US20180179274A1 (en) 2015-06-26 2018-06-28 Institute For Research In Biomedicine Proteins comprising a mutated lair-1 fragment and uses thereof
CA3000192C (en) 2015-09-29 2023-09-26 Crescendo Bioscience Biomarkers and methods for assessing psoriatic arthritis disease activity
WO2017058999A2 (en) 2015-09-29 2017-04-06 Crescendo Bioscience Biomarkers and methods for assessing response to inflammatory disease therapy withdrawal
WO2017059878A1 (en) 2015-10-07 2017-04-13 Humabs Biomed Sa Antibodies that potently neutralize hepatitis b virus and uses thereof
WO2017075045A2 (en) 2015-10-30 2017-05-04 Mayo Foundation For Medical Education And Research Antibodies to b7-h1
JP2019502715A (ja) 2016-01-13 2019-01-31 メディミューン,エルエルシー A型インフルエンザを治療する方法
WO2017184726A2 (en) 2016-04-20 2017-10-26 Crescendo Bioscience Biomarkers and methods for assessing response to inflammatory disease therapy
EP4141448A1 (en) 2016-07-10 2023-03-01 MeMed Diagnostics Ltd. Protein signatures for distinguishing between bacterial and viral infections
WO2018011796A1 (en) 2016-07-10 2018-01-18 Memed Diagnostics Ltd. Early diagnosis of infections
WO2018010789A1 (en) 2016-07-13 2018-01-18 Humabs Biomed Sa Novel antibodies specifically binding to zika virus epitopes and uses thereof
EP4033248B1 (en) 2016-08-10 2024-04-10 MeMed Diagnostics Ltd. System and method for analysis of mx1 and crp in blood
EP3612562A2 (en) 2017-04-19 2020-02-26 Institute for Research in Biomedicine Plasmodium sporozoite npdp peptides as vaccine and target novel malaria vaccines and antibodies binding to
US10696899B2 (en) 2017-05-09 2020-06-30 International Business Machines Corporation Light emitting shell in multi-compartment microcapsules
US10357921B2 (en) 2017-05-24 2019-07-23 International Business Machines Corporation Light generating microcapsules for photo-curing
US10900908B2 (en) * 2017-05-24 2021-01-26 International Business Machines Corporation Chemiluminescence for tamper event detection
US10392452B2 (en) 2017-06-23 2019-08-27 International Business Machines Corporation Light generating microcapsules for self-healing polymer applications
WO2019042555A1 (en) 2017-08-31 2019-03-07 Humabs Biomed Sa MULTISPECIFIC ANTIBODIES SPECIFICALLY BINDING TO ZIKA VIRUS EPITOPES AND USES THEREOF
CA3075518A1 (en) 2017-09-14 2019-03-21 Crescendo Bioscience, Inc. Biomarkers and methods for assessing myocardial infarction and serious infection risk in rheumatoid arthritis patients
WO2019161129A1 (en) 2018-02-14 2019-08-22 Mayo Foundation For Medical Education And Research Rescuing cancer patients from resistance to treatment with inhibitors of pd-1/pd-l1 interactions
WO2020092736A1 (en) 2018-10-31 2020-05-07 Mayo Foundation For Medical Education And Research Methods and materials for treating cancer
EP3873500A4 (en) 2018-10-31 2023-01-11 Mayo Foundation for Medical Education and Research METHODS AND MATERIALS FOR THE TREATMENT OF CANCER
EP3873495B1 (en) 2018-11-04 2024-06-26 Figene, LLC Methods and compositions for treatment of type 1 diabetes using fibroblasts as facilitators of islet engraftment
DK3898668T5 (da) 2018-12-19 2024-08-05 Humabs Biomed Sa Antistoffer der neutraliserer hepatitis b virus og anvendelser deraf
EP4021578A1 (en) 2019-08-29 2022-07-06 VIR Biotechnology, Inc. Antibody compositions and methods for treating hepatitis b virus infection
CN118465272B (zh) 2019-12-04 2025-08-19 珠海泰诺麦博制药股份有限公司 抗人巨细胞病毒抗体及其用途
WO2021152595A1 (en) 2020-01-29 2021-08-05 Memed Diagnostics Ltd. Methods of diagnosing and classifying viral infections
EP4171747A1 (en) 2020-06-24 2023-05-03 VIR Biotechnology, Inc. Engineered hepatitis b virus neutralizing antibodies and uses thereof
CA3199729A1 (en) 2020-11-24 2022-06-02 Monash University Induced stem cells
EP4284428A1 (en) 2021-01-26 2023-12-06 VIR Biotechnology, Inc. Compositions and methods for treating hepatitis b virus infection
WO2022189558A2 (en) 2021-03-10 2022-09-15 Mabylon Ag Antibodies against tdp-43 and methods of using the same
GB2613386A (en) 2021-12-02 2023-06-07 Apis Assay Tech Limited Diagnostic test
GB202203588D0 (en) 2022-03-15 2022-04-27 Argonaut Therapeutics Ltd Cancer diagnostic
WO2024261762A2 (en) 2023-06-21 2024-12-26 Metasight Diagnostics Ltd Liver fibrosis, nash and "at-risk" nash biomarkers and methods
WO2025054172A1 (en) 2023-09-05 2025-03-13 E-Star Biotech, LLC Formulations of manp and uses thereof
GB202316762D0 (en) 2023-11-01 2023-12-13 Rna Guardian Ltd Determination of cancer status
WO2026009223A1 (en) 2024-07-02 2026-01-08 Yeda Research And Development Co. Ltd. Computational methods for mapping peptides using metagenomic data

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154599B (nl) * 1970-12-28 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van specifiek bindende eiwitten en hun corresponderende bindbare stoffen, alsmede testverpakking.
US3690834A (en) * 1971-01-11 1972-09-12 Syva Co Ligand determination with spin labeled compounds by receptor displacement
US3852157A (en) * 1971-05-14 1974-12-03 Syva Corp Compounds for enzyme amplification assay
US3817837A (en) * 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
DE2440367C2 (de) * 1973-08-30 1984-03-15 General Electric Co., Schenectady, N.Y. Verfahren zum Herstellen multimolekularer Schichten aus immunologisch komplexierten Proteinen auf einem Substrat
SE388694B (sv) * 1975-01-27 1976-10-11 Kabi Ab Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar
IN142734B (cg-RX-API-DMAC10.html) * 1975-04-28 1977-08-20 Miles Lab
US4181650A (en) * 1975-08-25 1980-01-01 Maier Charles L Jr Procedure for the assay of pharmacologically immunologically and biochemically active compounds in biological fluids
US4080264A (en) * 1976-03-01 1978-03-21 Massachusetts Institute Of Technology Immunoassay by light scattering spectroscopy

Also Published As

Publication number Publication date
US4233402A (en) 1980-11-11
JPS54136896A (en) 1979-10-24
DE2913550A1 (de) 1979-10-18
CA1110541A (en) 1981-10-13
FR2434201B1 (fr) 1985-12-20
DE2913550C2 (cg-RX-API-DMAC10.html) 1988-05-19
GB2018986A (en) 1979-10-24
JPS6337348B2 (cg-RX-API-DMAC10.html) 1988-07-25
FR2434201A1 (fr) 1980-03-21

Similar Documents

Publication Publication Date Title
GB2018986B (en) Comperative protein binding assays
GB2021262B (en) Protein binding assays
GB2044449B (en) Fluorescer-labeled specific binding assay
AU522762B2 (en) Insolubilised proteins
GB2029754B (en) Surgival stapler
GB2016992A (en) Surgial stapler
AU538027B2 (en) Peptides
JPS555892A (en) Stapler
GB2013337B (en) Specific binding assay techniques
AU532335B2 (en) Peptides
GB2029323B (en) Bookbinding
JPS5529400A (en) Safetyyski binding
GB2036185B (en) Turbosupercharger
AU561649B2 (en) Antibodies to proteins
GB2029322B (en) Bookbinding
JPS54159966A (en) Sorter
JPS54150229A (en) Stapler
GB2066259B (en) Antibody serum
JPS5528770A (en) Sorter
GB8314851D0 (en) Modified proteins
JPS54152520A (en) Stapler
JPS5531518A (en) Stapler
ZA806957B (en) Vitamic protein supplement
AU4894279A (en) Feeding bridge
AU511043B2 (en) Anti-antihemocytic serum

Legal Events

Date Code Title Description
PE20 Patent expired after termination of 20 years

Effective date: 19990403