DK2307447T3 - Natriuretiske polypeptider med unikke farmakologiske profiler - Google Patents

Natriuretiske polypeptider med unikke farmakologiske profiler Download PDF

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Publication number
DK2307447T3
DK2307447T3 DK09774035.1T DK09774035T DK2307447T3 DK 2307447 T3 DK2307447 T3 DK 2307447T3 DK 09774035 T DK09774035 T DK 09774035T DK 2307447 T3 DK2307447 T3 DK 2307447T3
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DK
Denmark
Prior art keywords
natururetic
polypeptides
pharmacological profiles
unique pharmacological
unique
Prior art date
Application number
DK09774035.1T
Other languages
English (en)
Inventor
John C Burnett Jr
Candace Y W Lee
Original Assignee
Mayo Foundation
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Publication date
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Publication of DK2307447T3 publication Critical patent/DK2307447T3/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/58Atrial natriuretic factor complex; Atriopeptin; Atrial natriuretic peptide [ANP]; Cardionatrin; Cardiodilatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK09774035.1T 2008-07-02 2009-06-16 Natriuretiske polypeptider med unikke farmakologiske profiler DK2307447T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US7782408P 2008-07-02 2008-07-02
PCT/US2009/047534 WO2010002583A2 (en) 2008-07-02 2009-06-16 Natriuretic polypeptides with unique pharmacologic profiles

Publications (1)

Publication Number Publication Date
DK2307447T3 true DK2307447T3 (da) 2016-06-20

Family

ID=41466527

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09774035.1T DK2307447T3 (da) 2008-07-02 2009-06-16 Natriuretiske polypeptider med unikke farmakologiske profiler

Country Status (4)

Country Link
US (4) US8741842B2 (da)
EP (1) EP2307447B1 (da)
DK (1) DK2307447T3 (da)
WO (1) WO2010002583A2 (da)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK3404102T3 (da) 2004-04-21 2021-09-06 Alexion Pharma Inc Knogletilførselskonjugater og fremgangsmåde til anvendelse heraf til målretning af proteiner mod knogle
US20110152194A1 (en) * 2008-06-06 2011-06-23 Mayo Foundation For Medical Education And Research Chimeric natriuretic polypeptides and methods for inhibiting cardiac remodeling
EP2307447B1 (en) 2008-07-02 2016-03-09 Mayo Foundation For Medical Education And Research Natriuretic polypeptides with unique pharmacologic profiles
WO2010078325A2 (en) 2008-12-29 2010-07-08 Mayo Foundation For Medical Education And Research Natriuretic polypeptides for reducing or preventing restenosis
US20120108514A1 (en) 2009-07-09 2012-05-03 University Of Iowa Research Foundation Long acting atrial natriuretic peptide (la-anp) and methods for use thereof
KR101226165B1 (ko) 2009-07-23 2013-01-24 가부시키가이샤 이기스 피부 외용제 조성물
US9266939B2 (en) 2010-12-27 2016-02-23 Alexion Pharmaceuticals, Inc. Compositions comprising natriuretic peptides and methods of use thereof
US9102707B2 (en) 2011-08-30 2015-08-11 Mayo Foundation For Medical Education And Research Natriuretic polypeptides
WO2013103896A1 (en) 2012-01-06 2013-07-11 Mayo Foundation For Medical Education And Research Treating cardiovascular or renal diseases
US10052366B2 (en) 2012-05-21 2018-08-21 Alexion Pharmaceuticsl, Inc. Compositions comprising alkaline phosphatase and/or natriuretic peptide and methods of use thereof
US10822596B2 (en) 2014-07-11 2020-11-03 Alexion Pharmaceuticals, Inc. Compositions and methods for treating craniosynostosis
JP6787894B2 (ja) 2014-12-05 2020-11-18 アレクシオン ファーマシューティカルズ, インコーポレイテッド 組換えアルカリホスファターゼを用いた発作の処置
CA2973883A1 (en) 2015-01-28 2016-08-04 Alexion Pharmaceuticals, Inc. Methods of treating a subject with an alkaline phosphatase deficiency
WO2016194855A1 (ja) * 2015-05-29 2016-12-08 株式会社イギス 環状ペプチド並びに該環状ペプチドを含む医薬、外用剤および化粧料
CN108350440A (zh) 2015-08-17 2018-07-31 阿雷克森制药公司 碱性磷酸酯的制造
EP3355904A4 (en) 2015-09-28 2019-06-12 Alexion Pharmaceuticals, Inc. IDENTIFICATION OF EFFECTIVE DOSE SHEETS FOR TISSUE-SPECIFIC ALKALINE PHOSPHATASE ENZYMERSAT THERAPY OF HYPOPHOSPHATASIA
WO2017074466A1 (en) 2015-10-30 2017-05-04 Alexion Pharmaceuticals, Inc. Methods for treating craniosynostosis in a patient
US11065306B2 (en) 2016-03-08 2021-07-20 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in children
MX2018011833A (es) 2016-04-01 2019-02-13 Alexion Pharma Inc Tratamiento para la debilidad muscular con fosfatasas alcalinas.
US10898549B2 (en) 2016-04-01 2021-01-26 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia in adolescents and adults
WO2017214130A1 (en) 2016-06-06 2017-12-14 Alexion Pharmaceuticals, Inc. Metal impact on manufacturing of alkaline phosphatases
EP3500289A4 (en) 2016-08-18 2020-05-06 Alexion Pharmaceuticals, Inc. METHODS OF TREATING TRACHEOBRONCHOMALACIA
CA3057502A1 (en) 2017-03-31 2018-10-04 Alexion Pharmaceuticals, Inc. Methods for treating hypophosphatasia (hpp) in adults and adolescents
JP2021519590A (ja) 2018-03-30 2021-08-12 アレクシオン ファーマシューティカルズ, インコーポレイテッド 糖タンパク質の製造
US20220155322A1 (en) * 2019-03-15 2022-05-19 Mayo Foundation For Medical Education And Research Use of natriuretic peptides to assess and treat acute kidney injury

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4034074A (en) * 1974-09-19 1977-07-05 The Board Of Trustees Of Leland Stanford Junior University Universal reagent 2-site immunoradiometric assay using labelled anti (IgG)
US4098876A (en) 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4233402A (en) * 1978-04-05 1980-11-11 Syva Company Reagents and method employing channeling
US5703055A (en) * 1989-03-21 1997-12-30 Wisconsin Alumni Research Foundation Generation of antibodies through lipid mediated DNA delivery
US5296347A (en) 1991-02-08 1994-03-22 Ciba Corning Diagnostics Corp. Bridge immunoassay
WO2009015011A1 (en) * 2007-07-20 2009-01-29 Mayo Foundation For Medical Education And Research Natriuretic polypeptides
EP2307447B1 (en) 2008-07-02 2016-03-09 Mayo Foundation For Medical Education And Research Natriuretic polypeptides with unique pharmacologic profiles

Also Published As

Publication number Publication date
US20150322127A1 (en) 2015-11-12
WO2010002583A2 (en) 2010-01-07
EP2307447A2 (en) 2011-04-13
US9115209B2 (en) 2015-08-25
EP2307447B1 (en) 2016-03-09
US9771405B2 (en) 2017-09-26
US8741842B2 (en) 2014-06-03
US9365631B2 (en) 2016-06-14
US20160244500A1 (en) 2016-08-25
US20140228294A1 (en) 2014-08-14
WO2010002583A3 (en) 2010-04-22
EP2307447A4 (en) 2011-09-07
US20110152191A1 (en) 2011-06-23

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