GB1602290A - Substituted aralkyl amines and amino-aryl alkenes having therapeutic activity - Google Patents

Substituted aralkyl amines and amino-aryl alkenes having therapeutic activity Download PDF

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Publication number
GB1602290A
GB1602290A GB27992/77A GB2799277A GB1602290A GB 1602290 A GB1602290 A GB 1602290A GB 27992/77 A GB27992/77 A GB 27992/77A GB 2799277 A GB2799277 A GB 2799277A GB 1602290 A GB1602290 A GB 1602290A
Authority
GB
United Kingdom
Prior art keywords
compound
formula
group
methyl
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB27992/77A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astra Lakemedel AB
Original Assignee
Astra Lakemedel AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Lakemedel AB filed Critical Astra Lakemedel AB
Priority to GB27992/77A priority Critical patent/GB1602290A/en
Priority to FI782093A priority patent/FI64936C/fi
Priority to AU37612/78A priority patent/AU519960B2/en
Priority to DK782951A priority patent/DK295178A/da
Priority to CA306,650A priority patent/CA1111041A/en
Priority to IT50142/78A priority patent/IT1105075B/it
Priority to EP80105028A priority patent/EP0028682A3/de
Priority to DE7878850006T priority patent/DE2861781D1/de
Priority to NO782305A priority patent/NO146743C/no
Priority to EP78850006A priority patent/EP0000322B1/de
Priority to IE1333/78A priority patent/IE47628B1/en
Priority to AT0483578A priority patent/AT363456B/de
Priority to JP8181878A priority patent/JPS5439057A/ja
Priority to JP4677479A priority patent/JPS5511563A/ja
Priority to AT0493380A priority patent/AT368988B/de
Publication of GB1602290A publication Critical patent/GB1602290A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/62—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having at least three carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/68—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
    • C07C45/72—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms by reaction of compounds containing >C = O groups with the same or other compounds containing >C = O groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB27992/77A 1977-07-04 1977-07-04 Substituted aralkyl amines and amino-aryl alkenes having therapeutic activity Expired GB1602290A (en)

Priority Applications (15)

Application Number Priority Date Filing Date Title
GB27992/77A GB1602290A (en) 1977-07-04 1977-07-04 Substituted aralkyl amines and amino-aryl alkenes having therapeutic activity
FI782093A FI64936C (fi) 1977-07-04 1978-06-29 Foerfarande foer framstaellning av nya terapeutiskt verksamma foereningar av diarylalkylamintyp
AU37612/78A AU519960B2 (en) 1977-07-04 1978-06-29 Diarylalkylamines
DK782951A DK295178A (da) 1977-07-04 1978-06-29 Fremgangsmaade til fremstilling af terapeutisk aktive diarylalkylaminer
CA306,650A CA1111041A (en) 1977-07-04 1978-06-30 Primary diarylalkyl amines having antidepressive activity
IT50142/78A IT1105075B (it) 1977-07-04 1978-07-03 Procedimento per al preparazione di composti diarilalchilamminici con attivita' farmaceutica e prodotto ottenuto
EP80105028A EP0028682A3 (de) 1977-07-04 1978-07-03 Bei der Herstellung von Verbindungen mit antidepressiver oder tranquillisierender Wirkung nützliche Zwischenprodukte
DE7878850006T DE2861781D1 (en) 1977-07-04 1978-07-03 Compounds having an anti-depressive or tranquilizing activity, pharmaceutical compositions containing them, and processes and intermediates for their preparation
NO782305A NO146743C (no) 1977-07-04 1978-07-03 Analogifremgangsmaate for fremstilling av terapeutisk virksomme forbindelser.
EP78850006A EP0000322B1 (de) 1977-07-04 1978-07-03 Verbindungen mit antidepressiver und beruhigender Wirkung, ihre pharmazeutischen Zusammensetzungen, Verfahren und Zwischenprodukte zu ihrer Herstellung
IE1333/78A IE47628B1 (en) 1977-07-04 1978-07-03 Substituted aralkyl amines and amino-aryl alkenes having therapeutic activity
AT0483578A AT363456B (de) 1977-07-04 1978-07-04 Verfahren zur herstellung von neuen 1,1-diaryl-3-aminoalkanen, deren stereoisomeren und deren saeureadditionssalzen
JP8181878A JPS5439057A (en) 1977-07-04 1978-07-04 Novel compound with treating activity
JP4677479A JPS5511563A (en) 1977-07-04 1979-04-18 Movel compound having therapeutic activity
AT0493380A AT368988B (de) 1977-07-04 1980-10-03 Verfahren zur herstellung von neuen 1,1-diaryl-3- aminoalkenen, deren stereoisomeren und deren saeureadditionssalzen

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB27992/77A GB1602290A (en) 1977-07-04 1977-07-04 Substituted aralkyl amines and amino-aryl alkenes having therapeutic activity

Publications (1)

Publication Number Publication Date
GB1602290A true GB1602290A (en) 1981-11-11

Family

ID=10268546

Family Applications (1)

Application Number Title Priority Date Filing Date
GB27992/77A Expired GB1602290A (en) 1977-07-04 1977-07-04 Substituted aralkyl amines and amino-aryl alkenes having therapeutic activity

Country Status (9)

Country Link
JP (1) JPS5439057A (de)
AT (1) AT363456B (de)
AU (1) AU519960B2 (de)
CA (1) CA1111041A (de)
DK (1) DK295178A (de)
FI (1) FI64936C (de)
GB (1) GB1602290A (de)
IT (1) IT1105075B (de)
NO (1) NO146743C (de)

Also Published As

Publication number Publication date
DK295178A (da) 1979-01-05
FI64936B (fi) 1983-10-31
CA1111041A (en) 1981-10-20
NO146743B (no) 1982-08-23
AU3761278A (en) 1980-01-03
IT1105075B (it) 1985-10-28
IT7850142A0 (it) 1978-07-03
AT363456B (de) 1981-08-10
JPS5439057A (en) 1979-03-24
FI64936C (fi) 1984-02-10
AU519960B2 (en) 1982-01-07
NO146743C (no) 1982-12-01
ATA483578A (de) 1981-01-15
FI782093A (fi) 1979-01-05
NO782305L (no) 1979-01-05

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee