GB1601613A - Compositions for rectal use - Google Patents

Compositions for rectal use Download PDF

Info

Publication number
GB1601613A
GB1601613A GB7926/78A GB792678A GB1601613A GB 1601613 A GB1601613 A GB 1601613A GB 7926/78 A GB7926/78 A GB 7926/78A GB 792678 A GB792678 A GB 792678A GB 1601613 A GB1601613 A GB 1601613A
Authority
GB
United Kingdom
Prior art keywords
sodium
hereinbefore described
micellar solution
composition according
acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB7926/78A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of GB1601613A publication Critical patent/GB1601613A/en
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/02—Suppositories; Bougies; Bases therefor; Ovules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
GB7926/78A 1977-02-28 1978-02-28 Compositions for rectal use Expired GB1601613A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2172077A JPS53107408A (en) 1977-02-28 1977-02-28 Micellar preparation for rectal infusion

Publications (1)

Publication Number Publication Date
GB1601613A true GB1601613A (en) 1981-11-04

Family

ID=12062904

Family Applications (1)

Application Number Title Priority Date Filing Date
GB7926/78A Expired GB1601613A (en) 1977-02-28 1978-02-28 Compositions for rectal use

Country Status (5)

Country Link
US (1) US4156719A (enExample)
JP (1) JPS53107408A (enExample)
DE (1) DE2807248C2 (enExample)
FR (1) FR2381520A1 (enExample)
GB (1) GB1601613A (enExample)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2161380A (en) * 1984-07-13 1986-01-15 Nat Res Dev Pharmaceutical antifungal composition
US4760059A (en) * 1985-08-05 1988-07-26 Hoffmann-La Roche Inc. Rectal dosage form
US4944949A (en) * 1986-12-18 1990-07-31 T.I.L. Medical Ltd. Pharmaceutical delivery systems
AT395819B (de) * 1987-09-15 1993-03-25 Sandoz Ag Wasserloesliche monoester als solubilisatoren fuer pharmakologische wirkstoffe und pharmazeutische hilfsstoffe
WO1993008794A1 (en) * 1991-10-31 1993-05-13 Hyd Kutató-Fejlesztõ Kft. Pharmaceutical products for curing tumorous diseases and process for preparing same
WO1995025084A1 (en) * 1994-03-14 1995-09-21 Morten Sloth Weidner A method of rendering organic compounds soluble in fatty systems, novel chemical complexes of such compounds and various applications of the complexes
WO1997009978A1 (en) * 1995-09-13 1997-03-20 Morten Sloth Weidner Use of esters of polyhydric alcohols to enhance the oral bioavailability of drug substances as well as novel esters and pharmaceutical compositions containing them
US5756450A (en) * 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
DE3830494B4 (de) * 1987-09-15 2006-05-18 Novartis Ag Wasserlösliche Monoester als Solubilisatoren für pharmakologische Wirkstoffe und pharmazeutische Hilfsstoffe
US11679124B2 (en) 2018-03-19 2023-06-20 Epicyt Pharma Ab Composition for use in the treatment of conditions caused by calcium deficiency

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SE8206744D0 (sv) * 1982-11-26 1982-11-26 Fluidcarbon International Ab Preparat for kontrollerad avgivning av substanser
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CA1256799A (en) * 1984-02-22 1989-07-04 Walter Fuller Suppositories
JPS60149519A (ja) * 1984-09-03 1985-08-07 Kyoto Yakuhin Kogyo Kk 直腸投与用組成物
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CA1331559C (en) * 1986-04-21 1994-08-23 Jon Joseph Kabara Antimicrobial preservative compositions and methods
US5389366A (en) * 1986-09-19 1995-02-14 Yamanouchi Pharmaceutical Co., Ltd. Neocarzinostatin derivative composition for oral administration
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US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
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DE3924570A1 (de) * 1989-07-25 1991-01-31 Henning Berlin Gmbh Pharmazeutische zubereitung zur rektalen verabreichung
CA2033725C (en) * 1990-01-24 2001-05-29 Folker Pittrof Pharmaceutical and cosmetic compositions containing a salt of cholanic acid
JP3249147B2 (ja) * 1990-06-01 2002-01-21 キリン−アムジエン・インコーポレーテツド 生理活性蛋白含有経口製剤
US5891466A (en) * 1990-08-13 1999-04-06 Yesair; David W. Mixed Liped-Bicarbonate colloidal particles for delivering drugs or calories
ES2071332T3 (es) * 1990-08-13 1995-06-16 David W Yesair Particulas coloidales de lipidos mixtos-bicarbonato para administrar farmacos o calorias.
US5571517A (en) * 1990-08-13 1996-11-05 Yesair; David W. Mixed lipid-bicarbonate colloidal particles for delivering drugs or calories
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US5281420A (en) * 1992-05-19 1994-01-25 The Procter & Gamble Company Solid dispersion compositions of tebufelone
GB9212511D0 (en) * 1992-06-12 1992-07-22 Cortecs Ltd Pharmaceutical compositions
DK0589843T3 (da) 1992-09-25 2002-04-02 Novartis Ag Cyclosporinholdige farmaceutiske præparater
SE9302135D0 (sv) * 1993-06-18 1993-06-18 Kabi Pharmacia Ab New pharmaceutical composition
US20020099067A1 (en) * 1993-07-08 2002-07-25 Ulrich Posanski Pharmaceutical compositions for sparingly soluble therapeutic agents
GB9323588D0 (en) 1993-11-16 1994-01-05 Cortecs Ltd Hydrophobic preparation
ATE218359T1 (de) 1994-11-03 2002-06-15 Novartis Erfind Verwalt Gmbh Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung
GB9424901D0 (en) * 1994-12-09 1995-02-08 Cortecs Ltd Sequestration Agents
DE19544507B4 (de) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin enthaltende Präparate
GB9613858D0 (en) * 1996-07-02 1996-09-04 Cortecs Ltd Hydrophobic preparations
PT988046E (pt) * 1997-01-30 2004-12-31 Novartis Ag Composicoes farmaceuticas sem oleo contendo ciclosporina a
DE19722831A1 (de) * 1997-05-30 1998-12-03 Univ Halle Wittenberg Vehikelsysteme für Arzneistoffe
US6350458B1 (en) 1998-02-10 2002-02-26 Generex Pharmaceuticals Incorporated Mixed micellar drug deliver system and method of preparation
US7070799B1 (en) * 1998-02-10 2006-07-04 Generex Pharmaceuticals, Inc. Method for administering insulin to the buccal region
US6375975B1 (en) 1998-12-21 2002-04-23 Generex Pharmaceuticals Incorporated Pharmaceutical compositions for buccal and pulmonary application
US6451286B1 (en) 1998-12-21 2002-09-17 Generex Pharmaceuticals Incorporated Pharmaceutical compositions for buccal and pulmonary administration comprising an alkali metal alkyl sulfate and at least three micelle-forming compounds
US7087215B2 (en) * 1998-12-21 2006-08-08 Generex Pharmaceuticals Incorporated Methods of administering and enhancing absorption of pharmaceutical agents
US6849263B2 (en) * 1998-12-21 2005-02-01 Generex Pharmaceutical Incorporated Pharmaceutical compositions for buccal delivery of pain relief medications
US6761903B2 (en) 1999-06-30 2004-07-13 Lipocine, Inc. Clear oil-containing pharmaceutical compositions containing a therapeutic agent
US6248363B1 (en) * 1999-11-23 2001-06-19 Lipocine, Inc. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US20030236236A1 (en) * 1999-06-30 2003-12-25 Feng-Jing Chen Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
US6458383B2 (en) 1999-08-17 2002-10-01 Lipocine, Inc. Pharmaceutical dosage form for oral administration of hydrophilic drugs, particularly low molecular weight heparin
US6982281B1 (en) * 2000-11-17 2006-01-03 Lipocine Inc Pharmaceutical compositions and dosage forms for administration of hydrophobic drugs
US7732404B2 (en) * 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
US6867183B2 (en) * 2001-02-15 2005-03-15 Nobex Corporation Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US7030082B2 (en) * 2001-09-07 2006-04-18 Nobex Corporation Pharmaceutical compositions of drug-oligomer conjugates and methods of treating disease therewith
US7196059B2 (en) * 2001-09-07 2007-03-27 Biocon Limited Pharmaceutical compositions of insulin drug-oligomer conjugates and methods of treating diseases therewith
US6770625B2 (en) * 2001-09-07 2004-08-03 Nobex Corporation Pharmaceutical compositions of calcitonin drug-oligomer conjugates and methods of treating diseases therewith
GB2398495B (en) * 2003-01-23 2007-08-22 Kent G Lau A drug delivery preparation comprising at least one anti-tumour drug and a topical carrier for the drug
WO2005018607A1 (ja) * 2003-08-20 2005-03-03 Ajinomoto Co., Inc. 溶解性を改善した医薬品製剤
JP2006199589A (ja) * 2003-09-03 2006-08-03 Ltt Bio-Pharma Co Ltd 生理活性タンパク質またはペプチドを含有するナノ粒子およびその製造方法、ならびに当該ナノ粒子からなる外用剤
US20060003002A1 (en) * 2003-11-03 2006-01-05 Lipocine, Inc. Pharmaceutical compositions with synchronized solubilizer release
US20070219131A1 (en) * 2004-04-15 2007-09-20 Ben-Sasson Shmuel A Compositions capable of facilitating penetration across a biological barrier
CA2563533C (en) 2004-04-15 2013-10-01 Shmuel A. Ben-Sasson Compositions capable of facilitating penetration across a biological barrier
GB0522942D0 (en) * 2005-11-10 2005-12-21 Leigh Steven Dissolution composition
GB0623768D0 (en) * 2006-11-28 2007-01-10 Chopra Sunil A bleomycin preparation for use against skin tumours
RU2678833C2 (ru) * 2008-09-17 2019-02-04 Киазма Инк. Фармацевтические композиции и соответствующие способы доставки
US11304960B2 (en) * 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
EP2505188A1 (en) * 2009-12-02 2012-10-03 Bettina Heil Suppository for rectal, vaginal or urethral administration
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US9498485B2 (en) 2014-08-28 2016-11-22 Lipocine Inc. Bioavailable solid state (17-β)-hydroxy-4-androsten-3-one esters
SI3253401T1 (sl) 2015-02-03 2025-07-31 Amryt Endo, Inc. Zdravljenje akromegalije z oralnim oktreotidom
WO2016205423A2 (en) 2015-06-15 2016-12-22 Lipocine Inc. Composition and method for oral delivery of androgen prodrugs
CA3078723A1 (en) 2016-11-28 2018-05-31 Nachiappan Chidambaram Oral testosterone undecanoate therapy
EP3824296B1 (en) 2018-07-20 2026-04-01 Lipocine Inc. Oral pharmaceutical composition comprising testosterone tridecanoate and/or testosterone dodecanoate for treating liver diseases
US11141457B1 (en) 2020-12-28 2021-10-12 Amryt Endo, Inc. Oral octreotide therapy and contraceptive methods

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Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2161380A (en) * 1984-07-13 1986-01-15 Nat Res Dev Pharmaceutical antifungal composition
US4681876A (en) * 1984-07-13 1987-07-21 National Research Development Corporation Antifungal utility of bile acids
US4760059A (en) * 1985-08-05 1988-07-26 Hoffmann-La Roche Inc. Rectal dosage form
US4944949A (en) * 1986-12-18 1990-07-31 T.I.L. Medical Ltd. Pharmaceutical delivery systems
AT395819B (de) * 1987-09-15 1993-03-25 Sandoz Ag Wasserloesliche monoester als solubilisatoren fuer pharmakologische wirkstoffe und pharmazeutische hilfsstoffe
DE3830494B4 (de) * 1987-09-15 2006-05-18 Novartis Ag Wasserlösliche Monoester als Solubilisatoren für pharmakologische Wirkstoffe und pharmazeutische Hilfsstoffe
US5756450A (en) * 1987-09-15 1998-05-26 Novartis Corporation Water soluble monoesters as solubilisers for pharmacologically active compounds and pharmaceutical excipients and novel cyclosporin galenic forms
GB2276086B (en) * 1991-10-31 1995-09-27 Hyd Kutato Fejleszto Kft Anti-tumour compositions having low deuterium content
AT402692B (de) * 1991-10-31 1997-07-25 Hyd Kutato Fejlesztoe Kft Antigeschwulstmittel und verfahren zu ihrer herstellung
GB2276086A (en) * 1991-10-31 1994-09-21 Hyd Kutato Fejleszto Kft Pharmaceutical products for curing tumorous diseases and process for preparing same
WO1993008794A1 (en) * 1991-10-31 1993-05-13 Hyd Kutató-Fejlesztõ Kft. Pharmaceutical products for curing tumorous diseases and process for preparing same
WO1995025084A1 (en) * 1994-03-14 1995-09-21 Morten Sloth Weidner A method of rendering organic compounds soluble in fatty systems, novel chemical complexes of such compounds and various applications of the complexes
US6087391A (en) * 1994-03-14 2000-07-11 Weidner; Morten Sloth Method of rendering organic compounds soluble in fatty systems, novel chemical complexes of such compounds and various applications of the complexes
CN1114589C (zh) * 1994-03-14 2003-07-16 欧维塔有限公司 使有机化合物在脂肪体系中可溶的方法,这类化合物的配合物以及配合物的各种应用
WO1997009978A1 (en) * 1995-09-13 1997-03-20 Morten Sloth Weidner Use of esters of polyhydric alcohols to enhance the oral bioavailability of drug substances as well as novel esters and pharmaceutical compositions containing them
US11679124B2 (en) 2018-03-19 2023-06-20 Epicyt Pharma Ab Composition for use in the treatment of conditions caused by calcium deficiency

Also Published As

Publication number Publication date
JPS5619847B2 (enExample) 1981-05-09
DE2807248C2 (de) 1986-07-24
DE2807248A1 (de) 1978-08-31
FR2381520B1 (enExample) 1981-05-08
FR2381520A1 (fr) 1978-09-22
JPS53107408A (en) 1978-09-19
US4156719A (en) 1979-05-29

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Legal Events

Date Code Title Description
PS Patent sealed [section 19, patents act 1949]
PCNP Patent ceased through non-payment of renewal fee