GB1409959A - Derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production - Google Patents
Derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their productionInfo
- Publication number
- GB1409959A GB1409959A GB2458273A GB2458273A GB1409959A GB 1409959 A GB1409959 A GB 1409959A GB 2458273 A GB2458273 A GB 2458273A GB 2458273 A GB2458273 A GB 2458273A GB 1409959 A GB1409959 A GB 1409959A
- Authority
- GB
- United Kingdom
- Prior art keywords
- amino
- propan
- alkyl
- compound
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- JZEHWMUIAKALDN-UHFFFAOYSA-N 1-amino-3-phenoxypropan-2-ol Chemical class NCC(O)COC1=CC=CC=C1 JZEHWMUIAKALDN-UHFFFAOYSA-N 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 3
- VXKWVOPELVBBFB-UHFFFAOYSA-N 1-amino-3-(2-ethoxyphenoxy)propan-2-ol Chemical compound CCOC1=CC=CC=C1OCC(O)CN VXKWVOPELVBBFB-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- WKKTWTXTJLHHEK-UHFFFAOYSA-N 1-(4-butoxyphenoxy)propan-2-ol Chemical compound CCCCOC1=CC=C(OCC(C)O)C=C1 WKKTWTXTJLHHEK-UHFFFAOYSA-N 0.000 abstract 1
- OVPXWZQQDUKDFN-UHFFFAOYSA-N 1-pyridin-3-ylbutane-1,3-dione Chemical compound CC(=O)CC(=O)C1=CC=CN=C1 OVPXWZQQDUKDFN-UHFFFAOYSA-N 0.000 abstract 1
- IDBAICXGTSVLNM-UHFFFAOYSA-N 3-amino-1-pyridin-3-ylbut-2-en-1-one Chemical compound CC(N)=CC(=O)C1=CC=CN=C1 IDBAICXGTSVLNM-UHFFFAOYSA-N 0.000 abstract 1
- FKLJPTJMIBLJAV-UHFFFAOYSA-N Compound IV Chemical compound O1N=C(C)C=C1CCCCCCCOC1=CC=C(C=2OCCN=2)C=C1 FKLJPTJMIBLJAV-UHFFFAOYSA-N 0.000 abstract 1
- 239000004593 Epoxy Substances 0.000 abstract 1
- KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 abstract 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000003302 alkenyloxy group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000005133 alkynyloxy group Chemical group 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000005494 condensation Effects 0.000 abstract 1
- 238000009833 condensation Methods 0.000 abstract 1
- 239000007859 condensation product Substances 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000003944 halohydrins Chemical class 0.000 abstract 1
- 239000000543 intermediate Substances 0.000 abstract 1
- 229910052700 potassium Inorganic materials 0.000 abstract 1
- 239000011591 potassium Substances 0.000 abstract 1
- 235000002906 tartaric acid Nutrition 0.000 abstract 1
- 239000011975 tartaric acid Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyridine Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU65414 | 1972-05-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1409959A true GB1409959A (en) | 1975-10-15 |
Family
ID=19727058
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB2458273A Expired GB1409959A (en) | 1972-05-24 | 1973-05-23 | Derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production |
Country Status (25)
| Country | Link |
|---|---|
| US (1) | US3940406A (en, 2012) |
| JP (4) | JPS4941380A (en, 2012) |
| AR (4) | AR199905A1 (en, 2012) |
| AT (4) | AT326660B (en, 2012) |
| BE (1) | BE800005A (en, 2012) |
| BG (3) | BG22072A3 (en, 2012) |
| CA (1) | CA1015357A (en, 2012) |
| CH (4) | CH581621A5 (en, 2012) |
| CS (4) | CS183702B2 (en, 2012) |
| DD (1) | DD106835A5 (en, 2012) |
| DE (1) | DE2323354A1 (en, 2012) |
| ES (4) | ES415047A1 (en, 2012) |
| FR (1) | FR2185411B1 (en, 2012) |
| GB (1) | GB1409959A (en, 2012) |
| HU (1) | HU165663B (en, 2012) |
| IE (1) | IE37655B1 (en, 2012) |
| IL (1) | IL42333A (en, 2012) |
| LU (1) | LU65414A1 (en, 2012) |
| NL (1) | NL7306691A (en, 2012) |
| PH (3) | PH9827A (en, 2012) |
| PL (1) | PL91588B1 (en, 2012) |
| RO (2) | RO64607A (en, 2012) |
| SE (1) | SE399425B (en, 2012) |
| SU (4) | SU489309A3 (en, 2012) |
| ZA (1) | ZA733513B (en, 2012) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4088764A (en) * | 1973-12-27 | 1978-05-09 | Cassella Farbwerke Mainkur Aktiengesellschaft | Pharmaceutically active derivatives of 1-phenoxy-3-amino-propan-2-ol |
| US4066768A (en) * | 1973-12-27 | 1978-01-03 | Cassella Farbwerke Mainkur Aktiengesellschaft | Derivatives of 1-phenoxy-3-amino-propan-2-ol |
| US4139623A (en) * | 1974-05-14 | 1979-02-13 | C-G Corp. | Cyclic-substituted derivatives of 1-amino-2-propanol |
| CH591448A5 (en, 2012) * | 1974-05-14 | 1977-09-15 | Ciba Geigy Ag | |
| JPS528043A (en) * | 1975-07-10 | 1977-01-21 | Toagosei Chem Ind Co Ltd | Adhesive |
| US4097490A (en) * | 1975-09-25 | 1978-06-27 | Merck & Co., Inc. | Pyroglutamic acid salts of t-butylamino-2,3-dihydroxypropane |
| US4060601A (en) * | 1976-06-15 | 1977-11-29 | Merck & Co., Inc. | Certain lower-alkyl amino-2'-hydroxy-propoxy pyridines |
| JPH0774714B2 (ja) * | 1986-11-18 | 1995-08-09 | 中野冷機株式会社 | オープンショーケースの温度制御装置 |
| JP2858389B2 (ja) * | 1994-02-21 | 1999-02-17 | カシオ計算機株式会社 | 液晶表示装置およびその製造方法 |
| US5585388A (en) * | 1995-04-07 | 1996-12-17 | Sibia Neurosciences, Inc. | Substituted pyridines useful as modulators of acetylcholine receptors |
| US7244751B2 (en) * | 2003-02-14 | 2007-07-17 | Shenzhen Chipscreen Biosciences Ltd. | Histone deacetylase inhibitors of novel benzamide derivatives with potent differentiation and anti-proliferation activity |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1047927A (en) * | 1964-03-09 | 1966-11-09 | Ici Ltd | Alkanolamine derivatives |
| US3412154A (en) * | 1964-08-12 | 1968-11-19 | Parke Davis & Co | Amino-substituted phenone compounds |
| US3679693A (en) * | 1970-09-15 | 1972-07-25 | Smith Kline French Lab | N-pyridylalkyl-{62 -alkoxy-{62 -trifluoromethyl-phenalkylamines |
| BE787057A (fr) * | 1971-08-03 | 1973-02-01 | Cassella Farbwerke Mainkur Ag | Derives du phenoxy-1 amino-3 propanol-2 et medicaments qui en contiennent |
| CH578532A5 (en, 2012) * | 1971-08-03 | 1976-08-13 | Cassella Farbwerke Mainkur Ag |
-
1972
- 1972-05-24 LU LU65414A patent/LU65414A1/xx unknown
-
1973
- 1973-05-09 DE DE2323354A patent/DE2323354A1/de active Pending
- 1973-05-14 NL NL7306691A patent/NL7306691A/xx not_active Application Discontinuation
- 1973-05-16 HU HUCA346A patent/HU165663B/hu unknown
- 1973-05-21 SU SU1923622A patent/SU489309A3/ru active
- 1973-05-21 SU SU1923621A patent/SU563120A3/ru active
- 1973-05-21 IE IE805/73A patent/IE37655B1/xx unknown
- 1973-05-21 SU SU7301923620A patent/SU582755A3/ru active
- 1973-05-21 US US05/362,567 patent/US3940406A/en not_active Expired - Lifetime
- 1973-05-22 JP JP48056386A patent/JPS4941380A/ja active Pending
- 1973-05-22 BG BG24934A patent/BG22072A3/xx unknown
- 1973-05-22 IL IL42333A patent/IL42333A/en unknown
- 1973-05-22 BG BG023691A patent/BG20782A3/xx unknown
- 1973-05-22 DD DD170987A patent/DD106835A5/xx unknown
- 1973-05-22 JP JP48056387A patent/JPS4948675A/ja active Pending
- 1973-05-22 BG BG024936A patent/BG21851A3/xx unknown
- 1973-05-23 CH CH737673A patent/CH581621A5/xx not_active IP Right Cessation
- 1973-05-23 PH PH14648A patent/PH9827A/en unknown
- 1973-05-23 JP JP48056903A patent/JPS4948677A/ja active Pending
- 1973-05-23 ES ES415047A patent/ES415047A1/es not_active Expired
- 1973-05-23 AT AT450373A patent/AT326660B/de not_active IP Right Cessation
- 1973-05-23 AR AR248190A patent/AR199905A1/es active
- 1973-05-23 JP JP48056904A patent/JPS4948678A/ja active Pending
- 1973-05-23 ES ES415045A patent/ES415045A1/es not_active Expired
- 1973-05-23 AT AT450073A patent/AT326657B/de not_active IP Right Cessation
- 1973-05-23 SU SU1922038A patent/SU493958A3/ru active
- 1973-05-23 CS CS7300003715A patent/CS183702B2/cs unknown
- 1973-05-23 GB GB2458273A patent/GB1409959A/en not_active Expired
- 1973-05-23 CA CA172,038A patent/CA1015357A/en not_active Expired
- 1973-05-23 AR AR248189A patent/AR199904A1/es active
- 1973-05-23 CS CS7300003712A patent/CS183692B2/cs unknown
- 1973-05-23 ES ES415046A patent/ES415046A1/es not_active Expired
- 1973-05-23 RO RO7374886A patent/RO64607A/ro unknown
- 1973-05-23 SE SE7307242A patent/SE399425B/xx unknown
- 1973-05-23 CS CS7300003713A patent/CS183701B2/cs unknown
- 1973-05-23 CS CS7300003714A patent/CS181241B2/cs unknown
- 1973-05-23 AR AR248187A patent/AR199903A1/es active
- 1973-05-23 ES ES415044A patent/ES415044A1/es not_active Expired
- 1973-05-23 CH CH737773A patent/CH581622A5/xx not_active IP Right Cessation
- 1973-05-23 RO RO7300077378A patent/RO66268A/ro unknown
- 1973-05-23 CH CH737573A patent/CH581620A5/xx not_active IP Right Cessation
- 1973-05-23 CH CH737873A patent/CH596180A5/xx not_active IP Right Cessation
- 1973-05-23 ZA ZA733513A patent/ZA733513B/xx unknown
- 1973-05-23 AT AT450173A patent/AT326658B/de not_active IP Right Cessation
- 1973-05-23 PL PL1973162780A patent/PL91588B1/pl unknown
- 1973-05-23 AT AT450273A patent/AT326659B/de not_active IP Right Cessation
- 1973-05-24 FR FR7318866A patent/FR2185411B1/fr not_active Expired
- 1973-05-24 BE BE131502A patent/BE800005A/xx unknown
-
1974
- 1974-03-08 PH PH15601*A patent/PH9508A/en unknown
- 1974-03-08 PH PH15602*UA patent/PH9369A/en unknown
- 1974-05-23 AR AR248188A patent/AR200869A1/es active
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PS | Patent sealed [section 19, patents act 1949] |