GB0602778D0 - Novel compound - Google Patents
Novel compoundInfo
- Publication number
- GB0602778D0 GB0602778D0 GBGB0602778.3A GB0602778A GB0602778D0 GB 0602778 D0 GB0602778 D0 GB 0602778D0 GB 0602778 A GB0602778 A GB 0602778A GB 0602778 D0 GB0602778 D0 GB 0602778D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- novel compound
- novel
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (35)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0602778.3A GB0602778D0 (en) | 2006-02-10 | 2006-02-10 | Novel compound |
| JP2008553758A JP5616021B2 (ja) | 2006-02-10 | 2007-02-08 | ビフェニル−2−イルカルバミン酸1−[2−(2−クロロ−4−{[(r)−2−ヒドロキシ−2−(8−ヒドロキシ−2−オキソ−1,2−ジヒドロキノリン−5−イル)エチルアミノメチル]}−5−メトキシフェニルカルバモイル)エチル]ピペリジン−4−イルエステルのコハク酸塩および肺疾患治療におけるその使用 |
| JOP/2007/0037A JO3389B1 (ar) | 2006-02-10 | 2007-02-08 | ملح حمض سكسينيك من إستر لحمض باي فينيل-2-يل كارباميك 1-[2-(2-كلورو-4-{[(r) -2)- هيدوكسي-2-(8-هيدروكسي-2-أوكسو-1 ، 2-داي هيدرو كينولين -5- يل ) إثيل أمينوميثيل]} -5-ميثوكسي فينيل كاربامويل) إثيل] ببريدين-4-يل واستخدامه لعلاج الاضطرابات الرئوية) |
| LTEP07704449.3T LT1981872T (lt) | 2006-02-10 | 2007-02-08 | Bifenil-2-ilkarbamo rūgšties 1-[2-(2-chlor-4-{[(r)-2-hidroksi-2-(8-hidroksi-2-okso-1,2-dihidrochinolin-5-il)etilamino]metil]}-5-metoksifenilkarbamoil)etil]piperidin-4-ilo esterio gintaro rūgšties druska ir jos naudojimas plaučių susirgimų gydymui |
| SI200731963T SI1981872T1 (sl) | 2006-02-10 | 2007-02-08 | Sol jantarne kisline 1-(2-(2-kloro-4-(((R)-2-hidroksi-2-(8-hidroksi-2-okso-1,2-dihidrokinolin -5-il)etilamino)metil)-5-metoksifenilkarbamoil)etil)piperidin-4-il estra bifenil-2-ilkarbamske kisline in njena uporaba za zdravljenje pljučnih motenj |
| HUE07704449A HUE034315T2 (en) | 2006-02-10 | 2007-02-08 | Biphenyl-2-ylcarbamic acid 1- [2- (2-chloro-4 - {[(R) -2-hydroxy-2- (8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl) - succinic acid salt of ethylamino] methyl} -5-methoxyphenylcarbamoyl) ethyl] piperidin-4-yl ester and its use for the treatment of pulmonary disorders |
| SG201100933-9A SG169404A1 (en) | 2006-02-10 | 2007-02-08 | Succinic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{[(r)-2- hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl) ethylamino]methyl]}-5- methoxyphenylcarbamoyl)ethyl] piperidin-4-yl ester and its use for the treatment of pulmonary disorders |
| CA2641769A CA2641769C (en) | 2006-02-10 | 2007-02-08 | Succinic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{[(r)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl}-5-methoxyphenylcarbamoyl) ethyl] piperidin-4-yl ester and its use for the treatment of pulmonary disorders |
| CN2007800050282A CN101379057B (zh) | 2006-02-10 | 2007-02-08 | 联苯-2-基氨基甲酸1-[2-(2-氯-4-{[(r)-2-羟基-2-(8-羟基-2-氧代-1,2-二氢喹啉-5-基)乙基氨基]甲基}-5-甲氧基苯基氨甲酰基)乙基]哌啶-4-基酯的琥珀酸盐及其治疗肺疾病的用途 |
| PE2007000135A PE20071249A1 (es) | 2006-02-10 | 2007-02-08 | Sal de acido succinico de 1-[2-(2-cloro-4-{[(r)-2-hidroxi-2-(8-hidroxi-2-oxo-1,2-dihidroquinolin-5-il)etilamino]metil}-5-metoxifenilcarbamoil)etil]piperidin-4-il ester del acido bifenil-2-ilcarbamico |
| PE2010000996A PE20110120A1 (es) | 2006-02-10 | 2007-02-08 | Sal de acido succinico de 1-[2-(2-cloro-4-{[(r)-2-hidroxi-2-(8-hidroxi-2-oxo-1,2-dihidroquinolin-5-il)etilamino]metil}-5-metoxifenilcarbamoil)etil]piperidin-4-il ester del acido bifenil-2-ilcarbamico |
| PCT/EP2007/051196 WO2007090859A1 (en) | 2006-02-10 | 2007-02-08 | Succinic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{ [ (r)-2-hydroxy-2- (8-hydroxy-2-oxo-1, 2-dihydroquinolin-5-yl) eth ylaminoimethyl] } -5-methoxyphenylcarbamoyl) ethyl] piperidin-4-yl ester and its use for the treatment of pulmonary disorders |
| NZ570242A NZ570242A (en) | 2006-02-10 | 2007-02-08 | Succinic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{ [(R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylamino]methyl} -5-methoxyphenylcarbamoyl)ethyl]piperidin-4-yl ester and its use for the treatment of pulmonary disorders |
| PL07704449T PL1981872T3 (pl) | 2006-02-10 | 2007-02-08 | Sól kwasu bursztynowego estru 1-[2-(2-chloro-4-{[(r)-2-hydroksy-2-(8-hydroksy-2-okso-1,2-dihydrochinolin-5-ylo) ety-loaminometylo]}-5-metoksyfenylokarbamoilo)etylo]piperydyn-4-ylowego kwasu bifenyl-2-ilokarbaminowego i jego zastosowanie do leczenia zaburzeń czynności płuc |
| ES07704449.3T ES2640226T3 (es) | 2006-02-10 | 2007-02-08 | Sal de ácido succínico del éster 1-[2-(2-cloro-4-{[(R)-2-hidroxi-2-(8-hidroxi-2-oxo-1,2-dihidroquinolin-5-il)etilaminometil]}-5-metoxifenilcarbamoil)etil]piperidin-4-ílico del ácido bifenil-2-ilcarbámico y su uso para el tratamiento de trastornos pulmonares |
| PT77044493T PT1981872T (pt) | 2006-02-10 | 2007-02-08 | Sal de ácido succínico de éster 1-[2-(2-cloro-4-{[(r)-2-hidroxi-2-(8-hidroxi-2-oxo-1,2-di-hidroquinolin-5-il)etilamino]metil]}-5-metoxifenilcarbamoil)etil]piperidin-4-ílico de ácido bifenil-2-ilcarbâmico e a sua utilização para o tratamento de distúrbios pulmonares |
| US11/672,536 US7960551B2 (en) | 2006-02-10 | 2007-02-08 | Compound |
| ARP070100537A AR059409A1 (es) | 2006-02-10 | 2007-02-08 | Forma cristalina del succinato de 1-[2-(2-cloro-4-{[r-2-hidroxi-2-(8-hidroxi-2-oxo-1, 2-dihidroquinolin-5-il) etilamino] metil}-5- metoxifenilcarbamoil) etil] piperidin-4-il ester del acido bifenil-2-il-carbamico, una combinacion y una composicion farmaceutica que los contiene y el uso de la misma e |
| HRP20171304TT HRP20171304T1 (hr) | 2006-02-10 | 2007-02-08 | Sol s jantarnom kiselinom 1-[2-(2-klor-4-{[(r)-2-hidroksi-2-(8-hidroksi-2-okso-1,2-dihidrokinolin-5-il)etilaminometil]}-5-metoksifenilkarbamoil)etil]piperidin-4-ilnog estera bifenil-2-ilkarbaminske kiseline i njezina upotreba u liječenju plućnih poremećaja |
| KR20087022160A KR101488691B1 (ko) | 2006-02-10 | 2007-02-08 | 비페닐-2-일카르밤산 1-〔2-(2-클로로-4-{〔(r)-2-히드록시-2-(8-히드록시-2-옥소-1,2-디히드로퀴놀린-5-일)에틸아미노〕메틸}-5-메톡시페닐카르바모일)에틸〕피페리딘-4-일 에스테르의 석신산 염 및 이의 폐질환 치료를 위한 용도 |
| EA200801691A EA016580B1 (ru) | 2006-02-10 | 2007-02-08 | Соль янтарной кислоты 1-[2-(2-хлор-4-{[(r)-2-гидрокси-2-(8-гидрокси-2-оксо-1,2-дигидрохинолин-5-ил)этиламино]метил}-5-метоксифенилкарбамоил)этил]пиперидин-4-илового эфира бифенил-2-илкарбаминовой кислоты и ее применение для лечения легочных расстройств |
| BRPI0707559A BRPI0707559B8 (pt) | 2006-02-10 | 2007-02-08 | polimorfo de forma i do sal de ácido succínico de 1- [2- (2- cloro- 4- {[(r)- 2- hidróxi- 2- (8- hidróxi- 2- oxo- 1,2- diidroquinolin- 5- il) etilamino] meti1]}- 5- metoxifenilcarbamoil) etil] piperidin- 4- il éster de ácido bifenil- 2- il- carbâmico, seu processo de preparo e usos |
| TW096104636A TWI401251B (zh) | 2006-02-10 | 2007-02-08 | 新穎化合物 |
| EP07704449.3A EP1981872B1 (en) | 2006-02-10 | 2007-02-08 | Succinic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{[ (r)-2-hydroxy-2- (8-hydroxy-2-oxo-1, 2-dihydroquinolin-5-yl) eth ylaminoimethyl]} -5-methoxyphenylcarbamoyl) ethyl]piperidin-4-yl ester and its use for the treatment of pulmonary disorders |
| AU2007213767A AU2007213767B2 (en) | 2006-02-10 | 2007-02-08 | Succinic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{ [ (R)-2-hydroxy-2- (8-hydroxy-2-oxo-1, 2-dihydroquinolin-5-yl) ethylaminoimethyl] } -5-methoxyphenylcarbamoyl) ethyl] piperidin-4-yl ester and its use for the treatment of pulmonary disorders |
| DK07704449.3T DK1981872T3 (en) | 2006-02-10 | 2007-02-08 | Succinic salt of biphenyl-2-ylcarbamic acid 1- [2- (2-chloro-4 - {[(r) -2-hydroxy-2- (8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl) (5-methoxyphenylcarbamoyl) ethyl] piperidin-4-yl ester and its use in the treatment of pulmonary diseases. |
| UAA200809940A UA100364C2 (xx) | 2006-02-10 | 2007-08-02 | Сукцинат біфеніл-2-ілкарбамінової кислоти 1-$2-(2-хлор-4-{$(r)-2-гідрокси-2-(8-гідроксі-2-оксо-1,2-дигідрохінолін-5-іл)етиламіно]метил]}-5-метоксифенілкарбамоїл)етил]піперидин-4-іл-естеру та його застосування для лікування легеневих розладів |
| IL193103A IL193103A (en) | 2006-02-10 | 2008-07-29 | Biphenyl succinic acid salt-2-ram-carboxylic acid 1- [2- (2-chloro-4 - {[(r) -2-hydroxy-2- (8-hydroxy-2-oxo-2,1-dihydroquinoline) (5-yl) ethylamino-methyl-5-methoxyphenyl-carbamoyl) -piperidine-4-yeast ester and a pharmaceutical composition comprising the above for the treatment of health disorders |
| ZA200806782A ZA200806782B (en) | 2006-02-10 | 2008-08-05 | Succinic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4{[R)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethylaminoimethyl]}-5-methoxyphenyl-carbamoyl) ethyl] piperidin-4-YL ester and its use for the treatment of pulmonary disorders |
| NO20083425A NO341343B1 (no) | 2006-02-10 | 2008-08-05 | Ravsyresalt av bifenyl-2-ylkarbaminsyre 1-[2-(2-klor-4-{[(R)-2-hydroksy-2-(8-hydroksy-2-okso-1,2-dihydrokinolin-5-yl)etylamino]metyl]}-5- metoksyfenylkarbamoyl)etyl]piperidin-4-yl-ester, farmasøytisk preparat som omfatter ravsyresaltet, dets anvendelse, fremgangsmåte for fremstilling derav samt kombinasjon derav med et antiinflammatorisk middel |
| MYPI20083025A MY153656A (en) | 2006-02-10 | 2008-08-08 | Succinc acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{[(r)-2-hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl) ethylamino]methyl]}-5-methoxyphenylcarbamyl)ethyl]piperidin-4-yl ester and its use for the treatment of pulmonary disorders |
| CR10227A CR10227A (es) | 2006-02-10 | 2008-08-20 | Sal de ácido succínico del éster 1-[2-(2-cloro-4-{[(R)-2-hidroxi-2-(8-hidroxi-2-oxo-1,2-dihidroquinolin-5-il)etilmino]metil}-5-metoxifenilcarbamoil)etil]piperidin-4-ílicodelácidobifenil2ilcarbámicoysuusoparaeltratamientodetrastornospulmonar |
| MA31228A MA30273B1 (fr) | 2006-02-10 | 2008-09-10 | Sel d'acide succinique de l'ester 1-{2-(2-chloro-4-{[(r)-2-hydroxy-2-oxo-1,2- dihydroquinolin-5-yl)methoxyphenylcarbamoyl)ethyl]piperidin-5-ylique de l'acide biphenyl-2-ylcarbamique et son utilisation pour le traitement de troubles pulmonaires. |
| ARP160101036A AR104288A2 (es) | 2006-02-10 | 2016-04-15 | Forma cristalina i de la sal del ácido succínico de 1-[2-(2-cloro-4-[(r)-2-hidroxi-2-(8-hidroxi-2-oxo-1,2-dihidroquinolin-5-il)etilamino]metil-5-metoxifenilcarbamoil)etil]piperidin-4-il éster del ácido bifenil-2-ilcarbámico, composiciones, combinaciones y procedimiento para su preparación |
| CY20171100887T CY1119238T1 (el) | 2006-02-10 | 2017-08-22 | Αλας ηλεκτρικου οξεος του 1-[2-(2-χλωρο-4-{[(r)-2-υδροξυ-2-(8-υδροξυ-2-οξο-1,2-διϋδροκινολιν-5-υλ)αιθυλαμινο]μεθυλ]}-5-μεθοξυφαινυκαρβαμοϋλ)αιθυλ]πιπεριδιν-4-υλ εστερα διφαινυλ-2-υλκαρβαμικου οξεος και χρηση αυτου για την θεραπεια πνευμονικων διαταραχων |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0602778.3A GB0602778D0 (en) | 2006-02-10 | 2006-02-10 | Novel compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB0602778D0 true GB0602778D0 (en) | 2006-03-22 |
Family
ID=36119909
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB0602778.3A Ceased GB0602778D0 (en) | 2006-02-10 | 2006-02-10 | Novel compound |
Country Status (33)
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EA022030B1 (ru) | 2009-04-14 | 2015-10-30 | Глаксо Груп Лимитед | Способ получения 1-[2-(2-хлор-4-формил-5-метоксифенилкарбамоил)этил]пиперидин-4-илового эфира бифенил-2-илкарбаминовой кислоты |
| DK2599778T3 (en) | 2009-04-23 | 2017-06-26 | Theravance Respiratory Co Llc | Diamide compounds with muscarinic receptor antagonist and beta-2 adrenergic receptor agonist activity |
| AU2015234331B2 (en) * | 2009-04-23 | 2017-08-03 | Theravance Biopharma R&D Ip, Llc | Diamide compounds having muscarinic receptor antagonist and beta2 adrenergic receptor agonist activity |
| WO2011081937A1 (en) | 2009-12-15 | 2011-07-07 | Gilead Sciences, Inc. | Corticosteroid-beta-agonist-muscarinic antagonist compounds for use in therapy |
| EP2386555A1 (en) | 2010-05-13 | 2011-11-16 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities |
| ITRM20110083U1 (it) | 2010-05-13 | 2011-11-14 | De La Cruz Jose Antonio Freire | Piastra per la costruzione di carrelli per aeroplani |
| AR083115A1 (es) | 2010-09-30 | 2013-01-30 | Theravance Inc | Sales oxalato cristalinas de un compuesto diamida |
| CA2842276C (en) * | 2011-08-02 | 2020-11-24 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Pharmaceutical composition of oxidised avidin suitable for inhalation |
| EP2592078A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
| HK1215166A1 (zh) * | 2012-12-18 | 2016-08-19 | Almirall, S.A. | 具有β2肾上腺素激动剂及M3毒蕈碱拮抗剂活性的新型环己基和奎宁环基氨基甲酸酯衍生物 |
| TWI643853B (zh) | 2013-02-27 | 2018-12-11 | 阿爾米雷爾有限公司 | 同時具有β2腎上腺素受體促效劑和M3毒蕈鹼受體拮抗劑活性之2-氨基-1-羥乙基-8-羥基喹啉-2(1H)-酮衍生物之鹽類 |
| TWI641373B (zh) | 2013-07-25 | 2018-11-21 | 阿爾米雷爾有限公司 | 具有蕈毒鹼受體拮抗劑和β2腎上腺素受體促效劑二者之活性的2-胺基-1-羥乙基-8-羥基喹啉-2(1H)-酮衍生物之鹽 |
| TW201517906A (zh) | 2013-07-25 | 2015-05-16 | Almirall Sa | 含有maba化合物和皮質類固醇之組合 |
| TW201617343A (zh) | 2014-09-26 | 2016-05-16 | 阿爾米雷爾有限公司 | 具有β2腎上腺素促效劑及M3蕈毒拮抗劑活性之新穎雙環衍生物 |
| GB201500447D0 (en) * | 2015-01-12 | 2015-02-25 | Glaxosmithkline Ip Dev Ltd | Novel Combination Product |
| CN106632257B (zh) * | 2016-12-15 | 2019-02-12 | 上海市奉贤区中心医院 | Gsk961081及其中间体的合成方法 |
| US11484531B2 (en) | 2018-08-30 | 2022-11-01 | Theravance Biopharma R&D Ip, Llc | Methods for treating chronic obstructive pulmonary disease |
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