LT1981872T - Bifenil-2-ilkarbamo rūgšties 1-[2-(2-chlor-4-{[(r)-2-hidroksi-2-(8-hidroksi-2-okso-1,2-dihidrochinolin-5-il)etilamino]metil]}-5-metoksifenilkarbamoil)etil]piperidin-4-ilo esterio gintaro rūgšties druska ir jos naudojimas plaučių susirgimų gydymui - Google Patents

Bifenil-2-ilkarbamo rūgšties 1-[2-(2-chlor-4-{[(r)-2-hidroksi-2-(8-hidroksi-2-okso-1,2-dihidrochinolin-5-il)etilamino]metil]}-5-metoksifenilkarbamoil)etil]piperidin-4-ilo esterio gintaro rūgšties druska ir jos naudojimas plaučių susirgimų gydymui

Info

Publication number
LT1981872T
LT1981872T LTEP07704449.3T LT07704449T LT1981872T LT 1981872 T LT1981872 T LT 1981872T LT 07704449 T LT07704449 T LT 07704449T LT 1981872 T LT1981872 T LT 1981872T
Authority
LT
Lithuania
Prior art keywords
hydroxy
ylaminoimethyl
ylester
methoxyphenylcarbamoyl
diso
Prior art date
Application number
LTEP07704449.3T
Other languages
English (en)
Lithuanian (lt)
Inventor
Reshma Chudasama
Andrew Kennedy
Leanda Jane Kindon
Franck Patrick Mallet
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36119909&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=LT1981872(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of LT1981872T publication Critical patent/LT1981872T/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
LTEP07704449.3T 2006-02-10 2007-02-08 Bifenil-2-ilkarbamo rūgšties 1-[2-(2-chlor-4-{[(r)-2-hidroksi-2-(8-hidroksi-2-okso-1,2-dihidrochinolin-5-il)etilamino]metil]}-5-metoksifenilkarbamoil)etil]piperidin-4-ilo esterio gintaro rūgšties druska ir jos naudojimas plaučių susirgimų gydymui LT1981872T (lt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0602778.3A GB0602778D0 (en) 2006-02-10 2006-02-10 Novel compound
PCT/EP2007/051196 WO2007090859A1 (en) 2006-02-10 2007-02-08 Succinic acid salt of biphenyl-2-ylcarbamic acid 1-[2-(2-chloro-4-{ [ (r)-2-hydroxy-2- (8-hydroxy-2-oxo-1, 2-dihydroquinolin-5-yl) eth ylaminoimethyl] } -5-methoxyphenylcarbamoyl) ethyl] piperidin-4-yl ester and its use for the treatment of pulmonary disorders

Publications (1)

Publication Number Publication Date
LT1981872T true LT1981872T (lt) 2017-09-11

Family

ID=36119909

Family Applications (1)

Application Number Title Priority Date Filing Date
LTEP07704449.3T LT1981872T (lt) 2006-02-10 2007-02-08 Bifenil-2-ilkarbamo rūgšties 1-[2-(2-chlor-4-{[(r)-2-hidroksi-2-(8-hidroksi-2-okso-1,2-dihidrochinolin-5-il)etilamino]metil]}-5-metoksifenilkarbamoil)etil]piperidin-4-ilo esterio gintaro rūgšties druska ir jos naudojimas plaučių susirgimų gydymui

Country Status (33)

Country Link
US (1) US7960551B2 (enExample)
EP (1) EP1981872B1 (enExample)
JP (1) JP5616021B2 (enExample)
KR (1) KR101488691B1 (enExample)
CN (1) CN101379057B (enExample)
AR (2) AR059409A1 (enExample)
AU (1) AU2007213767B2 (enExample)
BR (1) BRPI0707559B8 (enExample)
CA (1) CA2641769C (enExample)
CR (1) CR10227A (enExample)
CY (1) CY1119238T1 (enExample)
DK (1) DK1981872T3 (enExample)
EA (1) EA016580B1 (enExample)
ES (1) ES2640226T3 (enExample)
GB (1) GB0602778D0 (enExample)
HR (1) HRP20171304T1 (enExample)
HU (1) HUE034315T2 (enExample)
IL (1) IL193103A (enExample)
JO (1) JO3389B1 (enExample)
LT (1) LT1981872T (enExample)
MA (1) MA30273B1 (enExample)
MY (1) MY153656A (enExample)
NO (1) NO341343B1 (enExample)
NZ (1) NZ570242A (enExample)
PE (2) PE20110120A1 (enExample)
PL (1) PL1981872T3 (enExample)
PT (1) PT1981872T (enExample)
SG (1) SG169404A1 (enExample)
SI (1) SI1981872T1 (enExample)
TW (1) TWI401251B (enExample)
UA (1) UA100364C2 (enExample)
WO (1) WO2007090859A1 (enExample)
ZA (1) ZA200806782B (enExample)

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EP2592078A1 (en) 2011-11-11 2013-05-15 Almirall, S.A. New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities
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TWI643853B (zh) 2013-02-27 2018-12-11 阿爾米雷爾有限公司 同時具有β2腎上腺素受體促效劑和M3毒蕈鹼受體拮抗劑活性之2-氨基-1-羥乙基-8-羥基喹啉-2(1H)-酮衍生物之鹽類
TWI641373B (zh) 2013-07-25 2018-11-21 阿爾米雷爾有限公司 具有蕈毒鹼受體拮抗劑和β２腎上腺素受體促效劑二者之活性的２－胺基－１－羥乙基－８－羥基喹啉－２（１Ｈ）－酮衍生物之鹽
TW201517906A (zh) 2013-07-25 2015-05-16 Almirall Sa 含有ｍａｂａ化合物和皮質類固醇之組合
TW201617343A (zh) 2014-09-26 2016-05-16 阿爾米雷爾有限公司 具有β２腎上腺素促效劑及Ｍ３蕈毒拮抗劑活性之新穎雙環衍生物
GB201500447D0 (en) * 2015-01-12 2015-02-25 Glaxosmithkline Ip Dev Ltd Novel Combination Product
CN106632257B (zh) * 2016-12-15 2019-02-12 上海市奉贤区中心医院 Gsk961081及其中间体的合成方法
US11484531B2 (en) 2018-08-30 2022-11-01 Theravance Biopharma R&D Ip, Llc Methods for treating chronic obstructive pulmonary disease

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Also Published As

Publication number Publication date
SI1981872T1 (sl) 2017-10-30
CA2641769A1 (en) 2007-08-16
TWI401251B (zh) 2013-07-11
CR10227A (es) 2008-10-29
BRPI0707559B1 (pt) 2021-01-12
JP5616021B2 (ja) 2014-10-29
EA200801691A1 (ru) 2009-02-27
EA016580B1 (ru) 2012-06-29
CA2641769C (en) 2014-02-04
CY1119238T1 (el) 2018-02-14
BRPI0707559A8 (pt) 2019-01-29
NO20083425L (no) 2008-09-09
IL193103A (en) 2013-06-27
US20070281971A1 (en) 2007-12-06
BRPI0707559B8 (pt) 2021-05-25
PT1981872T (pt) 2017-09-13
AR104288A2 (es) 2017-07-12
SG169404A1 (en) 2011-03-30
WO2007090859A1 (en) 2007-08-16
US7960551B2 (en) 2011-06-14
PL1981872T3 (pl) 2017-11-30
BRPI0707559A2 (pt) 2011-05-10
CN101379057B (zh) 2013-02-13
EP1981872B1 (en) 2017-06-21
PE20071249A1 (es) 2008-01-16
MA30273B1 (fr) 2009-03-02
AU2007213767B2 (en) 2012-04-26
ZA200806782B (en) 2009-10-28
PE20110120A1 (es) 2011-03-08
UA100364C2 (xx) 2012-12-25
KR101488691B1 (ko) 2015-02-02
EP1981872A1 (en) 2008-10-22
KR20080114723A (ko) 2008-12-31
HUE034315T2 (en) 2018-02-28
AR059409A1 (es) 2008-04-09
JO3389B1 (ar) 2019-03-13
NO341343B1 (no) 2017-10-16
AU2007213767A1 (en) 2007-08-16
MY153656A (en) 2015-03-13
DK1981872T3 (en) 2017-09-11
JP2009526018A (ja) 2009-07-16
IL193103A0 (en) 2009-02-11
CN101379057A (zh) 2009-03-04
TW200800948A (en) 2008-01-01
NZ570242A (en) 2011-09-30
HRP20171304T1 (hr) 2017-10-20
ES2640226T3 (es) 2017-11-02
GB0602778D0 (en) 2006-03-22

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