GB0007308D0 - Process for preparing crystalline form | of cabergoline - Google Patents
Process for preparing crystalline form | of cabergolineInfo
- Publication number
- GB0007308D0 GB0007308D0 GBGB0007308.0A GB0007308A GB0007308D0 GB 0007308 D0 GB0007308 D0 GB 0007308D0 GB 0007308 A GB0007308 A GB 0007308A GB 0007308 D0 GB0007308 D0 GB 0007308D0
- Authority
- GB
- United Kingdom
- Prior art keywords
- cabergoline
- crystalline form
- preparing crystalline
- preparing
- crystalline
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- KORNTPPJEAJQIU-KJXAQDMKSA-N Cabaser Chemical compound C1=CC([C@H]2C[C@H](CN(CC=C)[C@@H]2C2)C(=O)N(CCCN(C)C)C(=O)NCC)=C3C2=CNC3=C1 KORNTPPJEAJQIU-KJXAQDMKSA-N 0.000 title 1
- 229960004596 cabergoline Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Ophthalmology & Optometry (AREA)
- Psychology (AREA)
- Reproductive Health (AREA)
- Pulmonology (AREA)
- Endocrinology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (34)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0007308.0A GB0007308D0 (en) | 2000-03-24 | 2000-03-24 | Process for preparing crystalline form | of cabergoline |
| PE2001000237A PE20011140A1 (es) | 2000-03-24 | 2001-03-13 | Proceso para preparar forma i cristalina de cabergolina |
| MXPA02009283A MXPA02009283A (es) | 2000-03-24 | 2001-03-19 | Procedimiento para preparar la forma i cristalina de cabergolina. |
| HK03104554.7A HK1052348B (zh) | 2000-03-24 | 2001-03-19 | 製備卡麥角林結晶i型的方法 |
| CZ20023176A CZ20023176A3 (cs) | 2000-03-24 | 2001-03-19 | Způsob výroby krystalické formy i kabergolinu a solvatované formy v kabergolinu |
| CA002402836A CA2402836A1 (en) | 2000-03-24 | 2001-03-19 | Process for preparing crystalline form i of cabergoline |
| EEP200200545A EE05088B1 (et) | 2000-03-24 | 2001-03-19 | Meetod kabergoliini kristallvormi I saamiseks, kabergoliini solvaat ning selle valmistamine |
| PT01936098T PT1272489E (pt) | 2000-03-24 | 2001-03-19 | Processo para a preparacao da forma i cristalina de cabergolina |
| SI200130045T SI1272489T1 (en) | 2000-03-24 | 2001-03-19 | Process for preparing crystalline form i of cabergoline |
| IL15098501A IL150985A0 (en) | 2000-03-24 | 2001-03-19 | Process for preparing crystalline form i of cabergoline |
| AT01936098T ATE250601T1 (de) | 2000-03-24 | 2001-03-19 | Prozess zur herstellung der kristallinen form i von cabergolin |
| ARP010101263A AR032449A1 (es) | 2000-03-24 | 2001-03-19 | Un procedimiento para producir la forma i cristalina de cabergolina, es decir, 1((6-alilergolin-8beta-il)-carbonil)-1-(3-dimetilaminopropil)-3-etilurea, forma v de solvato de cabergolina, y un procedimiento para producir la forma v de solvato de cabergolina |
| PCT/EP2001/003099 WO2001070740A1 (en) | 2000-03-24 | 2001-03-19 | Process for preparing crystalline form i of cabergoline |
| DK01936098T DK1272489T3 (da) | 2000-03-24 | 2001-03-19 | Fremgangsmåde til præparation af cabergolins krystallinske form I |
| EA200201016A EA005928B1 (ru) | 2000-03-24 | 2001-03-19 | Способ получения кристаллической формы i каберголина |
| CNB018070051A CN1188412C (zh) | 2000-03-24 | 2001-03-19 | 制备卡麦角林结晶ⅰ型的方法 |
| EP01936098A EP1272489B1 (en) | 2000-03-24 | 2001-03-19 | Process for preparing crystalline form i of cabergoline |
| JP2001568941A JP4184666B2 (ja) | 2000-03-24 | 2001-03-19 | カベルゴリンの結晶性形態iを調製するための方法 |
| ES01936098T ES2208602T3 (es) | 2000-03-24 | 2001-03-19 | Procedimiento de preparacion de la forma cristalina i de cabergolina. |
| NZ521316A NZ521316A (en) | 2000-03-24 | 2001-03-19 | Process for preparing crystalline forms I and V of cabergoline |
| BR0109507-2A BR0109507A (pt) | 2000-03-24 | 2001-03-19 | Processo para preparação de forma i, cristalina, de carbegolina |
| US10/239,636 US6727363B2 (en) | 2000-03-24 | 2001-03-19 | Process for preparing crystalline form I of cabergoline |
| SK1358-2002A SK13582002A3 (sk) | 2000-03-24 | 2001-03-19 | Spôsob výroby kryštalickej formy I kabergolínu a solvatovanej formy V kabergolínu |
| DE60100858T DE60100858T2 (de) | 2000-03-24 | 2001-03-19 | Prozess zur herstellung der kristallinen form i von cabergolin |
| HU0300591A HUP0300591A3 (en) | 2000-03-24 | 2001-03-19 | Process for preparing crystalline form i of cabergoline |
| KR1020027012590A KR100827558B1 (ko) | 2000-03-24 | 2001-03-19 | 카베르골린의 결정성 형태 i의 제조방법 |
| PL01358253A PL358253A1 (en) | 2000-03-24 | 2001-03-19 | Process for preparing crystalline form i of cabergoline |
| AU62110/01A AU780747B2 (en) | 2000-03-24 | 2001-03-19 | Process for preparing crystalline form I of cabergoline |
| MYPI20011364A MY134189A (en) | 2000-03-24 | 2001-03-22 | Process for preparing crystalline form i of cabergoline |
| ZA200206045A ZA200206045B (en) | 2000-03-24 | 2002-07-29 | Process for preparing crystalline form I of cabergoline. |
| IL150985A IL150985A (en) | 2000-03-24 | 2002-07-30 | Process for the preparation and crystalline form I of cabergoline, an intermediate substance which is solvate toluene V-form of cabergoline and its preparation |
| NO20024321A NO20024321L (no) | 2000-03-24 | 2002-09-10 | Fremgangsmate for fremstilling av krystallinsk form I av kabergolin |
| US10/698,737 US6953854B2 (en) | 2000-03-24 | 2003-10-31 | Process for preparing crystalline Form I of cabergoline |
| AU2005203071A AU2005203071B2 (en) | 2000-03-24 | 2005-07-14 | Process for preparing crystalline form I of cabergoline |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0007308.0A GB0007308D0 (en) | 2000-03-24 | 2000-03-24 | Process for preparing crystalline form | of cabergoline |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB0007308D0 true GB0007308D0 (en) | 2000-05-17 |
Family
ID=9888433
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GBGB0007308.0A Ceased GB0007308D0 (en) | 2000-03-24 | 2000-03-24 | Process for preparing crystalline form | of cabergoline |
Country Status (31)
| Country | Link |
|---|---|
| US (2) | US6727363B2 (https=) |
| EP (1) | EP1272489B1 (https=) |
| JP (1) | JP4184666B2 (https=) |
| KR (1) | KR100827558B1 (https=) |
| CN (1) | CN1188412C (https=) |
| AR (1) | AR032449A1 (https=) |
| AT (1) | ATE250601T1 (https=) |
| AU (2) | AU780747B2 (https=) |
| BR (1) | BR0109507A (https=) |
| CA (1) | CA2402836A1 (https=) |
| CZ (1) | CZ20023176A3 (https=) |
| DE (1) | DE60100858T2 (https=) |
| DK (1) | DK1272489T3 (https=) |
| EA (1) | EA005928B1 (https=) |
| EE (1) | EE05088B1 (https=) |
| ES (1) | ES2208602T3 (https=) |
| GB (1) | GB0007308D0 (https=) |
| HK (1) | HK1052348B (https=) |
| HU (1) | HUP0300591A3 (https=) |
| IL (2) | IL150985A0 (https=) |
| MX (1) | MXPA02009283A (https=) |
| MY (1) | MY134189A (https=) |
| NO (1) | NO20024321L (https=) |
| NZ (1) | NZ521316A (https=) |
| PE (1) | PE20011140A1 (https=) |
| PL (1) | PL358253A1 (https=) |
| PT (1) | PT1272489E (https=) |
| SI (1) | SI1272489T1 (https=) |
| SK (1) | SK13582002A3 (https=) |
| WO (1) | WO2001070740A1 (https=) |
| ZA (1) | ZA200206045B (https=) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0007308D0 (en) | 2000-03-24 | 2000-05-17 | Pharmacia & Upjohn Spa | Process for preparing crystalline form | of cabergoline |
| GB0007307D0 (en) | 2000-03-24 | 2000-05-17 | Pharmacia & Upjohn Spa | Crystalline form || of cabergoline |
| DE10053397A1 (de) * | 2000-10-20 | 2002-05-02 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| DE10043321B4 (de) * | 2000-08-24 | 2005-07-28 | Neurobiotec Gmbh | Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung |
| DE10064453A1 (de) * | 2000-12-16 | 2002-07-04 | Schering Ag | Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen |
| MXPA04008915A (es) * | 2002-03-15 | 2005-06-20 | Pharmacia Corp | Proceso para la preparacion de la forma cristalina 1 de la cabergolina. |
| KR100605794B1 (ko) * | 2002-03-15 | 2006-08-01 | 파마시아 코포레이션 | 카베르골린의 제1형 결정을 제조하는 방법 |
| IL155545A (en) | 2003-04-21 | 2009-12-24 | Finetech Pharmaceutical Ltd | Solvate form of cabergoline |
| EP1620101A4 (en) * | 2003-05-08 | 2008-07-09 | Ivax Pharmaceuticals Sro | POLYMORPHS OF CABERGOLIN |
| GB0409785D0 (en) * | 2004-04-30 | 2004-06-09 | Resolution Chemicals Ltd | Preparation of cabergoline |
| US7339060B2 (en) | 2005-03-23 | 2008-03-04 | Resolution Chemicals, Ltd. | Preparation of cabergoline |
| GB0515430D0 (en) * | 2005-07-27 | 2005-08-31 | Resolution Chemicals Ltd | Preparation of cabergoline |
| GB0505965D0 (en) | 2005-03-23 | 2005-04-27 | Resolution Chemicals Ltd | Preparation of cabergoline |
| EP1925616A1 (en) * | 2006-10-26 | 2008-05-28 | LEK Pharmaceuticals D.D. | Process for the preparation of crystal forms of cabergoline via stable solvates of cabergoline |
| EP1953157A1 (en) | 2007-01-31 | 2008-08-06 | LEK Pharmaceuticals D.D. | New crystal form of cabergoline |
| EP2185169A2 (en) * | 2007-08-29 | 2010-05-19 | Max Zeller Söhne AG | Use of vitex agnus castus extracts for preparing a medicament |
| EP4074552B1 (en) * | 2021-04-16 | 2024-04-03 | Thermo King LLC | Electrical connection unit |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3019322A1 (de) | 1980-05-21 | 1981-12-03 | Merck Patent Gmbh, 6100 Darmstadt | Psychopharmakon sowie verwendung von adenosinderivaten |
| US4526892A (en) | 1981-03-03 | 1985-07-02 | Farmitalia Carlo Erba, S.P.A. | Dimethylaminoalkyl-3-(ergoline-8'βcarbonyl)-ureas |
| GB2103603B (en) * | 1981-08-11 | 1985-04-11 | Erba Farmitalia | Ergoline derivatives |
| GB9205439D0 (en) * | 1992-03-12 | 1992-04-22 | Erba Carlo Spa | Process for the synthesis of ergoline derivatives |
| WO1995005176A1 (en) | 1993-08-18 | 1995-02-23 | Alcon Laboratories, Inc. | Use of ergoline derivatives for the treatment of glaucoma |
| EP1075278A1 (en) | 1998-01-13 | 2001-02-14 | AstraZeneca UK Limited | PHARMACEUTICAL COMPOSITIONS COMPRISING A COMPOUND HAVING DOPAMINE (D 2?) RECEPTOR AGONIST ACTIVITY AND A COMPOUND (B) HAVING $g(b) 2?-ADRENORECEPTOR AGONIST ACTIVITY |
| SK13312000A3 (sk) | 1998-03-27 | 2001-05-10 | Pharmacia And Upjohn Company | Použitie kabergolínu pri liečbe syndrómu nepokojných nôh |
| GB0007308D0 (en) | 2000-03-24 | 2000-05-17 | Pharmacia & Upjohn Spa | Process for preparing crystalline form | of cabergoline |
| GB0007307D0 (en) | 2000-03-24 | 2000-05-17 | Pharmacia & Upjohn Spa | Crystalline form || of cabergoline |
| GB0007309D0 (en) | 2000-03-24 | 2000-05-17 | Pharmacia & Upjohn Spa | Crystalline form V|| of cabergoline |
-
2000
- 2000-03-24 GB GBGB0007308.0A patent/GB0007308D0/en not_active Ceased
-
2001
- 2001-03-13 PE PE2001000237A patent/PE20011140A1/es not_active Application Discontinuation
- 2001-03-19 EA EA200201016A patent/EA005928B1/ru unknown
- 2001-03-19 SK SK1358-2002A patent/SK13582002A3/sk unknown
- 2001-03-19 DK DK01936098T patent/DK1272489T3/da active
- 2001-03-19 NZ NZ521316A patent/NZ521316A/en unknown
- 2001-03-19 CA CA002402836A patent/CA2402836A1/en not_active Withdrawn
- 2001-03-19 AR ARP010101263A patent/AR032449A1/es unknown
- 2001-03-19 AU AU62110/01A patent/AU780747B2/en not_active Ceased
- 2001-03-19 HK HK03104554.7A patent/HK1052348B/zh not_active IP Right Cessation
- 2001-03-19 BR BR0109507-2A patent/BR0109507A/pt not_active Application Discontinuation
- 2001-03-19 CZ CZ20023176A patent/CZ20023176A3/cs unknown
- 2001-03-19 ES ES01936098T patent/ES2208602T3/es not_active Expired - Lifetime
- 2001-03-19 WO PCT/EP2001/003099 patent/WO2001070740A1/en not_active Ceased
- 2001-03-19 EP EP01936098A patent/EP1272489B1/en not_active Expired - Lifetime
- 2001-03-19 PT PT01936098T patent/PT1272489E/pt unknown
- 2001-03-19 CN CNB018070051A patent/CN1188412C/zh not_active Expired - Fee Related
- 2001-03-19 DE DE60100858T patent/DE60100858T2/de not_active Expired - Fee Related
- 2001-03-19 IL IL15098501A patent/IL150985A0/xx active IP Right Grant
- 2001-03-19 EE EEP200200545A patent/EE05088B1/xx not_active IP Right Cessation
- 2001-03-19 HU HU0300591A patent/HUP0300591A3/hu unknown
- 2001-03-19 US US10/239,636 patent/US6727363B2/en not_active Expired - Fee Related
- 2001-03-19 PL PL01358253A patent/PL358253A1/xx not_active Application Discontinuation
- 2001-03-19 AT AT01936098T patent/ATE250601T1/de not_active IP Right Cessation
- 2001-03-19 MX MXPA02009283A patent/MXPA02009283A/es active IP Right Grant
- 2001-03-19 SI SI200130045T patent/SI1272489T1/xx unknown
- 2001-03-19 KR KR1020027012590A patent/KR100827558B1/ko not_active Expired - Fee Related
- 2001-03-19 JP JP2001568941A patent/JP4184666B2/ja not_active Expired - Fee Related
- 2001-03-22 MY MYPI20011364A patent/MY134189A/en unknown
-
2002
- 2002-07-29 ZA ZA200206045A patent/ZA200206045B/xx unknown
- 2002-07-30 IL IL150985A patent/IL150985A/en not_active IP Right Cessation
- 2002-09-10 NO NO20024321A patent/NO20024321L/no not_active Application Discontinuation
-
2003
- 2003-10-31 US US10/698,737 patent/US6953854B2/en not_active Expired - Fee Related
-
2005
- 2005-07-14 AU AU2005203071A patent/AU2005203071B2/en not_active Ceased
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| AT | Applications terminated before publication under section 16(1) |