FR2751224B1 - Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs - Google Patents

Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs

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Publication number
FR2751224B1
FR2751224B1 FR9609338A FR9609338A FR2751224B1 FR 2751224 B1 FR2751224 B1 FR 2751224B1 FR 9609338 A FR9609338 A FR 9609338A FR 9609338 A FR9609338 A FR 9609338A FR 2751224 B1 FR2751224 B1 FR 2751224B1
Authority
FR
France
Prior art keywords
polynucleotide vaccine
vaccine formula
reproductive conditions
pig reproductive
formula against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
FR9609338A
Other languages
English (en)
French (fr)
Other versions
FR2751224A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Animal Health France SAS
Original Assignee
Rhone Merieux SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Merieux SA filed Critical Rhone Merieux SA
Priority to FR9609338A priority Critical patent/FR2751224B1/fr
Priority to ARP970103116A priority patent/AR007864A1/es
Priority to CNB971965587A priority patent/CN1329513C/zh
Priority to PL97331249A priority patent/PL190615B1/pl
Priority to PCT/FR1997/001313 priority patent/WO1998003658A1/fr
Priority to AU36991/97A priority patent/AU735291B2/en
Priority to CA2261346A priority patent/CA2261346C/en
Priority to KR1019980710903A priority patent/KR100496249B1/ko
Priority to BR9710740A priority patent/BR9710740A/pt
Priority to UA99020959A priority patent/UA77935C2/uk
Priority to JP10506628A priority patent/JP2001500111A/ja
Priority to EP97933745A priority patent/EP0912743B1/fr
Priority to ES97933745T priority patent/ES2251030T3/es
Priority to HU9903822A priority patent/HUP9903822A3/hu
Priority to UAA200610210A priority patent/UA91675C2/ru
Priority to CNA200710127053XA priority patent/CN101121023A/zh
Priority to DE69734284T priority patent/DE69734284T2/de
Priority to DK97933745T priority patent/DK0912743T3/da
Priority to CO97040979A priority patent/CO4750676A1/es
Priority to TW086112707A priority patent/TW589190B/zh
Publication of FR2751224A1 publication Critical patent/FR2751224A1/fr
Application granted granted Critical
Publication of FR2751224B1 publication Critical patent/FR2751224B1/fr
Priority to US09/232,468 priority patent/US6207165B1/en
Priority to US09/784,984 priority patent/US6576243B1/en
Priority to RU2002133052/13A priority patent/RU2305559C2/ru
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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    • AHUMAN NECESSITIES
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00Medicinal preparations containing antigens or antibodies
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    • A61K39/102Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • AHUMAN NECESSITIES
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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FR9609338A 1996-07-19 1996-07-19 Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs Expired - Lifetime FR2751224B1 (fr)

Priority Applications (23)

Application Number Priority Date Filing Date Title
FR9609338A FR2751224B1 (fr) 1996-07-19 1996-07-19 Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs
ARP970103116A AR007864A1 (es) 1996-07-19 1997-07-11 Formula de vacuna porcina, su utilizacion y kit de vacunacion que la contiene.
CNA200710127053XA CN101121023A (zh) 1996-07-19 1997-07-15 抗猪生殖和呼吸疾病的多核苷酸疫苗制剂
PCT/FR1997/001313 WO1998003658A1 (fr) 1996-07-19 1997-07-15 Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs
AU36991/97A AU735291B2 (en) 1996-07-19 1997-07-15 Polynucleotide vaccine formula against porcine reproductive and respiratory pathologies
CA2261346A CA2261346C (en) 1996-07-19 1997-07-15 Polynucleotide vaccine formula for treating porcine respiratory and reproductive diseases
KR1019980710903A KR100496249B1 (ko) 1996-07-19 1997-07-15 돼지의호흡기및생식기질환치료용폴리뉴클레오티드백신제제
BR9710740A BR9710740A (pt) 1996-07-19 1997-07-15 FÄrmula de vacina polinucleotidica contra as patologias respiratÄrias e de reprodu-Æo de porcos
UA99020959A UA77935C2 (uk) 1996-07-19 1997-07-15 Композиція вакцини для свиней, спосіб та набір для вакцинації
JP10506628A JP2001500111A (ja) 1996-07-19 1997-07-15 ブタの生殖病および呼吸病に対するポリヌクレオチドワクチン処方
EP97933745A EP0912743B1 (fr) 1996-07-19 1997-07-15 Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs
ES97933745T ES2251030T3 (es) 1996-07-19 1997-07-15 Formula de vacuna polinucleotida para el tratamiento de patologias respiratorias y reproductivas de los cerdos.
CNB971965587A CN1329513C (zh) 1996-07-19 1997-07-15 抗猪生殖和呼吸疾病的多核苷酸疫苗制剂
UAA200610210A UA91675C2 (ru) 1996-07-19 1997-07-15 Формула полинуклеотидной вакцины против дыхательных паталогий и паталогий размножения свиней
PL97331249A PL190615B1 (pl) 1996-07-19 1997-07-15 Kompozycja szczepionki dla świń, zastosowanie kompozycji szczepionki, zestaw do szczepienia, szczepionka dla świń i zastosowanie plazmidu
DE69734284T DE69734284T2 (de) 1996-07-19 1997-07-15 Zusammensetzung eines polynukleotidvakzins zur behandlung von atemwegs- und fortpflanzungsbezogenen erkrankungen des schweins
DK97933745T DK0912743T3 (da) 1996-07-19 1997-07-15 Polynukleotidvaccinepræparat til behandling af luftvejs- og reproduktionssygdomme hos svin
HU9903822A HUP9903822A3 (en) 1996-07-19 1997-07-15 Polynucleotide vaccine formula for treating porcine respiratory and reproductive diseases
CO97040979A CO4750676A1 (es) 1996-07-19 1997-07-18 Formula de vacuna plinucleotidica contra patologias respira- torias y de reproduccion en los cerdos
TW086112707A TW589190B (en) 1996-07-19 1997-09-03 Polynucleotide vaccine formula against porcine reproductive and respiratory pathologies
US09/232,468 US6207165B1 (en) 1996-07-19 1999-01-15 Polynucleotide formula against porcine reproductive and respiratory pathologies
US09/784,984 US6576243B1 (en) 1996-07-19 2001-02-16 Polynucleotide vaccine formula against porcine reproductive and respiratory pathologies
RU2002133052/13A RU2305559C2 (ru) 1996-07-19 2002-12-09 Вакцина свиней против респираторных патологий и патологий репродукции свиней

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Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU762901B2 (en) * 1996-07-19 2003-07-10 Merial Polynucleotide vaccine formula for treating porcine respiratory and reproductive diseases
EP0863151A1 (en) * 1997-02-12 1998-09-09 Akzo Nobel N.V. "Canine parvovirus dna vaccines"
CA2223029A1 (en) 1997-02-12 1998-08-12 Akzo Nobel Nv Canine parvovirus dna vaccines
FR2776294B1 (fr) * 1998-03-20 2001-06-22 Merial Sas Nouveaux circovirus porcins ; vaccins et reactifs de diagnostic
US7211379B2 (en) * 1997-10-03 2007-05-01 Merial Sas Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2
US7192594B2 (en) * 1997-10-03 2007-03-20 Merial Limited Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
US6517843B1 (en) 1999-08-31 2003-02-11 Merial Reduction of porcine circovirus-2 viral load with inactivated PCV-2
FR2781159B1 (fr) * 1998-07-06 2000-10-06 Merial Sas Vaccin circovirus et parvovirus porcin
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
JP3795751B2 (ja) * 1997-12-11 2006-07-12 ユニバーシティ オブ サスカッチェワン ブタからの離乳後多全身系消耗症候群ウイルス
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
FR2804028B1 (fr) * 2000-01-21 2004-06-04 Merial Sas Vaccins adn ameliores pour animaux de rente
KR20030054139A (ko) * 2001-12-24 2003-07-02 학교법인 건국대학교 돼지 오제스키병 바이러스의 gD 유전자를 포함하는재조합 발현 벡터 및 이를 이용한 DNA 백신
US7906311B2 (en) 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
US20060160759A1 (en) * 2002-09-28 2006-07-20 Jianzhu Chen Influenza therapeutic
EP1606419A1 (en) 2003-03-18 2005-12-21 Quantum Genetics Ireland Limited Systems and methods for improving protein and milk production of dairy herds
US7468273B2 (en) 2003-05-01 2008-12-23 Meial Limited Canine GHRH gene, polypeptides and methods of use
WO2005049794A2 (en) 2003-11-13 2005-06-02 University Of Georgia Research Foundation, Inc. Methods of characterizing infectious bursal disease virus
US7527967B2 (en) * 2003-11-25 2009-05-05 Academia Sinica Recombinant baculovirus and virus-like particle
WO2005112544A2 (en) 2004-02-19 2005-12-01 The Governors Of The University Of Alberta Leptin promoter polymorphisms and uses thereof
RS51324B (sr) 2005-04-25 2010-12-31 Merial Ltd. Vakcine protiv nipah virusa
US20080241184A1 (en) 2005-08-25 2008-10-02 Jules Maarten Minke Canine influenza vaccines
US7771995B2 (en) 2005-11-14 2010-08-10 Merial Limited Plasmid encoding human BMP-7
EP3147296A1 (en) 2005-11-14 2017-03-29 Merial, Inc. Gene therapy for renal failure
US7862821B2 (en) 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
US20080274137A1 (en) * 2007-05-02 2008-11-06 Jean Christophe Francis Audonnet DNA plasmids having improved expression and stability
UA100692C2 (ru) 2007-05-02 2013-01-25 Мериал Лимитед Днк-плазмиды, имеющие повышенную экспрессию и стабильность
EP3542815A1 (en) 2008-11-28 2019-09-25 Boehringer Ingelheim Animal Health USA Inc. Recombinant avian influenza vaccine and uses thereof
EP2414386B1 (en) 2009-04-03 2016-01-27 Merial Limited Newcastle disease virus vectored avian vaccines
US10633667B2 (en) 2009-12-28 2020-04-28 Boehringer Ingelheim Animal Health USA Inc. Recombinant NDV antigen and uses thereof
US20130197612A1 (en) 2010-02-26 2013-08-01 Jack W. Lasersohn Electromagnetic Radiation Therapy
ES2617743T3 (es) 2010-03-12 2017-06-19 Merial, Inc. Vacunas recombinantes del virus de la lengua azul y sus utilizaciones
CN102370976B (zh) * 2010-08-09 2014-06-11 中山大学 猪流感病毒和猪口蹄疫病毒的混合病毒样颗粒、制备方法和应用
CN102373181B (zh) * 2010-08-09 2014-06-11 中山大学 猪流感病毒和猪蓝耳病病毒混合病毒样颗粒、制备方法和应用
EP2611460B1 (en) 2010-08-31 2016-10-05 Merial, Inc. Newcastle disease virus vectored herpesvirus vaccines
WO2012090073A2 (en) 2010-12-30 2012-07-05 The Netherlands Cancer Institute Methods and compositions for predicting chemotherapy sensitivity
EP2694678A2 (en) 2011-04-04 2014-02-12 Netherland Cancer Institute Methods and compositions for predicting resistance to anticancer treatment
US20140296248A1 (en) 2011-04-04 2014-10-02 Stichting het Nederlands Kanker Instiuut-Antoni van Leeuwenhoek ziekenhuis Methods and compositions for predicting resistance to anticancer treatment
US9216213B2 (en) 2011-04-20 2015-12-22 Merial, Inc. Adjuvanted rabies vaccine with improved viscosity profile
WO2012149038A1 (en) 2011-04-25 2012-11-01 Advanced Bioscience Laboratories, Inc. Truncated hiv envelope proteins (env), methods and compositions related thereto
KR20140033096A (ko) 2011-05-07 2014-03-17 래보래토리오 아비-멕스, 에스.에이. 데 씨.브이. 바이러스성 벡터를 이용한 prrs에 대한 재조합 백신
BR112013030321A2 (pt) * 2011-05-27 2017-07-11 Sinovet Beijing Biotechnology Co Ltd composição de vacina, método para preparar a composição de vacina, uso da composição de vacina, método para imunizar um porco, cepa de vacina contra csfv e uso de uma célula no cultivo de uma cepa de vacina contra csfv.
CA2837582C (en) 2011-05-27 2021-03-02 Merial Limited Genetic vaccines against hendra virus and nipah virus
CA2837375C (en) 2011-06-01 2019-07-16 Merial Limited Needle-free administration of prrsv vaccines
MX350096B (es) 2011-08-12 2017-08-25 Merial Inc Preservación asistida con vacío de productos biológicos, en particular de vacunas.
WO2013093629A2 (en) 2011-12-20 2013-06-27 Netherlands Cancer Institute Modular vaccines, methods and compositions related thereto
EP3466443B1 (en) 2012-02-14 2020-12-16 Boehringer Ingelheim Animal Health USA Inc. Recombinant poxviral vectors expressing both rabies and ox40 proteins, and vaccines made therefrom
SI2814508T1 (sl) 2012-02-14 2017-10-30 Merial, Inc. Rotavirusna podenotska cepiva ter postopki njihove izdelave in uporaba
WO2013138776A1 (en) 2012-03-16 2013-09-19 Merial Limited Novel methods for providing long-term protective immunity against rabies in animals, based upon administration of replication-deficient flavivirus expressing rabies g
EP2861248B1 (en) 2012-06-13 2017-11-15 Merial, Inc. Reassortant btv and ahsv vaccines
CN102807989B (zh) * 2012-08-01 2014-04-23 中国人民解放军军事医学科学院军事兽医研究所 犬科和/或猫科动物疫病重组活载体疫苗的制备方法
HK1216006A1 (zh) 2013-03-12 2016-10-07 Boehringer Ingelheim Animal Health USA Inc. 反向遺傳學施馬倫貝格病毒疫苗組合物,和其使用方法
JP6236144B2 (ja) * 2013-05-31 2017-11-22 普莱柯生物工程股▲ふん▼有限公司 豚ヘルペスウイルス、ワクチン組成物及びその製造方法と応用
EP3049106A1 (en) 2013-09-25 2016-08-03 Zoetis Services LLC Pcv2b divergent vaccine composition and methods of use
CN105251000B (zh) * 2014-09-30 2018-12-14 普莱柯生物工程股份有限公司 猪伪狂犬病病毒疫苗组合物及其制备方法和应用
WO2016073410A1 (en) 2014-11-03 2016-05-12 Merial, Inc. Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus
ES3050936T3 (en) 2015-06-23 2025-12-23 Boehringer Ingelheim Vetmedica Gmbh Prrsv minor protein-containing recombinant viral vectors and methods of making and use thereof
CN105693827B (zh) * 2015-06-29 2020-05-15 普莱柯生物工程股份有限公司 一种猪伪狂犬病病毒亚单位疫苗及其制备方法和应用
CN104998256A (zh) * 2015-07-14 2015-10-28 天津瑞普生物技术股份有限公司 一种猪用三联灭活疫苗的制备方法
WO2017031120A1 (en) 2015-08-20 2017-02-23 Merial, Inc. Fcv recombinant vaccines and uses thereof
HUE065661T2 (hu) 2015-09-29 2024-06-28 Boehringer Ingelheim Animal Health Usa Inc Kutya parvovírus (CPV) vírusszerû részecske (VLP) vakcinák és alkalmazásuk
DK3380119T3 (da) 2015-11-23 2021-11-15 Boehringer Ingelheim Animal Health Usa Inc Fmdv- og e2-fusionsproteiner og anvendelser deraf
TWI760322B (zh) 2016-01-29 2022-04-11 美商百靈佳殷格翰動物保健美國有限公司 重組腺病毒載體裝載之fmdv疫苗及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8901651A (nl) * 1989-06-29 1991-01-16 Centraal Diergeneeskundig Inst Vaccin tegen pestivirusinfecties, zoals varkenspest; daarvoor bruikbare nucleotidesequenties en polypeptiden.
US6592873B1 (en) * 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
KR100374295B1 (ko) * 1993-02-08 2003-12-24 바이엘 코포레이션 돼지생식및호흡증후군바이러스의생육방법과백신에서그의용도
ATE475668T1 (de) * 1994-01-27 2010-08-15 Univ Massachusetts Medical Immunisierung durch impfung von dns transkriptionseinheit
US5516905A (en) * 1994-08-30 1996-05-14 University Of Massachusetts Medical Center Antibiotic compounds and methods to treat gram-positive bacterial and mycoplasmal infections
AU711915B2 (en) * 1995-12-21 1999-10-21 Dimminaco Ag Plasmid vaccine against pseudorabies virus

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BR9710740A (pt) 1999-08-17
AR007864A1 (es) 1999-11-24
PL331249A1 (en) 1999-07-05
RU2002133052A (ru) 2005-01-20
FR2751224A1 (fr) 1998-01-23
US6207165B1 (en) 2001-03-27
UA77935C2 (uk) 2007-02-15
CA2261346C (en) 2012-01-03
JP2001500111A (ja) 2001-01-09
EP0912743B1 (fr) 2005-09-28
HUP9903822A2 (hu) 2000-03-28
DK0912743T3 (da) 2006-01-30
DE69734284D1 (de) 2006-02-09
AU3699197A (en) 1998-02-10
CN101121023A (zh) 2008-02-13
CA2261346A1 (en) 1998-01-29
KR20000065256A (ko) 2000-11-06
KR100496249B1 (ko) 2006-01-27
DE69734284T2 (de) 2006-07-13
HUP9903822A3 (en) 2010-01-28
CN1225684A (zh) 1999-08-11
WO1998003658A1 (fr) 1998-01-29
EP0912743A1 (fr) 1999-05-06
CN1329513C (zh) 2007-08-01
ES2251030T3 (es) 2006-04-16
US6576243B1 (en) 2003-06-10
UA91675C2 (ru) 2010-08-25
AU735291B2 (en) 2001-07-05
RU2305559C2 (ru) 2007-09-10
TW589190B (en) 2004-06-01
PL190615B1 (pl) 2005-12-30
CO4750676A1 (es) 1999-03-31

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