JP2001500111A - ブタの生殖病および呼吸病に対するポリヌクレオチドワクチン処方 - Google Patents
ブタの生殖病および呼吸病に対するポリヌクレオチドワクチン処方Info
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- JP2001500111A JP2001500111A JP10506628A JP50662898A JP2001500111A JP 2001500111 A JP2001500111 A JP 2001500111A JP 10506628 A JP10506628 A JP 10506628A JP 50662898 A JP50662898 A JP 50662898A JP 2001500111 A JP2001500111 A JP 2001500111A
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Abstract
Description
Claims (1)
- 【特許請求の範囲】 1. 少なくとも三つのポリヌクレオチドワクチン結合価を含む、ブタの生殖病 および/または呼吸病に対するブタワクチン処方であって、各ポリヌクレオチド ワクチン結合価は、宿主細胞でインビボで発現するように一つのブタ病原体結合 価の遺伝子を有するプラスミドを含み、各結合価はアウジェスキー病ウイルス、 ブタインフルエンザウイルス(SIV)、ブタ不明病ウイルス、パルボビロシスウイ ルス、通常の豚コレラウイルスおよびアクチノバシラス症の原因バクテリアから 成る群の中から選択され、上記プラスミドは、結合価毎に、アウジェスキー病ウ イルスについてはgBおよびgD、ブタインフルエンザウイルスについてはHA、NPお よびN、不明病ウイルスについてはE、ORF3、M、パルボビロシスウイルスにつ いてはVP2、通常の豚コレラウイルスについてはE1、E2、アクチノバシラス症に ついてはapxI、apxIIおよびapxIIIで構成される群の中から選択される一つ以上 の遺伝子を含むことを特徴とするワクチン処方。 2. 少なくともアウジェスキーおよびブタインフルエンザ結合価を含む請求項 1に記載のワクチン処方。 3. 不明病およびアクチノバシラス症から選択される結合価のうち少なくとも 一つをさらに含む請求項2に記載のワクチン処方。 4. 通常の豚コレラ結合価を含む請求項3に記載のワクチン処方。 5. 不明病、パルボビロシスおよび通常の豚コレラ結合価の群から選択される 少なくとも一つの結合価をさらに含む請求項2に記載のワクチン処方。 6. 豚コレラウイルスHAおよび/またはNP遺伝子を含む請求項1に記載のワク チン処方。 7.不明病ウイルスEおよび/またはORF3遺伝子を含む請求項1に記載のワク チン処方。 8. アウジェスキーからのgBおよびgDを含む請求項1または2に記載のワクチ ン処方。 9. 0.1〜10ml、好ましくは1〜5mlの投与量で与えられる請求項1〜8のい ずれか一項に記載のワクチン処方。 10. 0.1〜0.9ml、特に、0.2〜0.6ml、好ましくは0.4〜0.5mlの投与量で、液体 噴射、好ましくは数回の噴射によって皮内投与するのに適した請求項1〜8のい ずれか一項に記載のワクチン処方。 11. 各プラスミド型につき10ng〜1mg、好ましくは100ng〜500μg、さらに好 ましくは1μg〜500μgを含む請求項10に記載のワクチン処方。 12. ポリヌクレオチドワクチンによってコードされた抗原、または交差保護を もたらす抗原を有する請求項1〜11のいずれか一項に記載のワクチン処方の、生 全ワクチン、不活性化全ワクチン、サブユニットワクチン、組換えワクチンから 成る群より選択される初期ワクチンを接種したブタに予防接種するためのワクチ ン製造での使用。 13. 請求項1〜11のいずれか一項に記載のワクチン処方と、生全ワクチン、不 活性化全ワクチン、サブユニットワクチン、組換えワクチンから成る群より選択 されたワクチンとを組み合わせた予防接種キットであって、初期ワクチンが、ポ リヌクレオチドワクチンによってコードされた抗原または交差保護をもたらす抗 原を有し、後者のワクチンを初期予防接種として投与するか、上記ワクチン処方 を用いた追加免疫として投与することを特徴とするキット。 14. 生全ワクチン、不活性化全ワクチン、サブユニットワクチン、組換えワク チンから成る群より選択されたポリヌクレオチドワクチンプラスミドによってコ ードされた抗原または交差保護をもたらす抗原を有する初期ワクチンの追加免疫 として処方可能であることを記載した指示書を有する、請求項1〜11のいずれか 一項に記載のワクチン処方。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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FR96/09338 | 1996-07-19 | ||
FR9609338A FR2751224B1 (fr) | 1996-07-19 | 1996-07-19 | Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs |
PCT/FR1997/001313 WO1998003658A1 (fr) | 1996-07-19 | 1997-07-15 | Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs |
Publications (2)
Publication Number | Publication Date |
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JP2001500111A true JP2001500111A (ja) | 2001-01-09 |
JP2001500111A5 JP2001500111A5 (ja) | 2005-03-10 |
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Application Number | Title | Priority Date | Filing Date |
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JP10506628A Ceased JP2001500111A (ja) | 1996-07-19 | 1997-07-15 | ブタの生殖病および呼吸病に対するポリヌクレオチドワクチン処方 |
Country Status (20)
Country | Link |
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US (2) | US6207165B1 (ja) |
EP (1) | EP0912743B1 (ja) |
JP (1) | JP2001500111A (ja) |
KR (1) | KR100496249B1 (ja) |
CN (2) | CN1329513C (ja) |
AR (1) | AR007864A1 (ja) |
AU (1) | AU735291B2 (ja) |
BR (1) | BR9710740A (ja) |
CA (1) | CA2261346C (ja) |
CO (1) | CO4750676A1 (ja) |
DE (1) | DE69734284T2 (ja) |
DK (1) | DK0912743T3 (ja) |
ES (1) | ES2251030T3 (ja) |
FR (1) | FR2751224B1 (ja) |
HU (1) | HUP9903822A3 (ja) |
PL (1) | PL190615B1 (ja) |
RU (1) | RU2305559C2 (ja) |
TW (1) | TW589190B (ja) |
UA (2) | UA77935C2 (ja) |
WO (1) | WO1998003658A1 (ja) |
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JP2017526335A (ja) * | 2015-06-29 | 2017-09-14 | 普莱柯生物工程股▲ふん▼有限公司 | ヘルペスウイルスサブユニットワクチン及びその製造方法と応用 |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
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JP2016520294A (ja) * | 2013-05-31 | 2016-07-14 | プリケ生物工程股▲ふん▼有限公司 | 豚ヘルペスウイルス、ワクチン組成物及びその製造方法と応用 |
JP2017526335A (ja) * | 2015-06-29 | 2017-09-14 | 普莱柯生物工程股▲ふん▼有限公司 | ヘルペスウイルスサブユニットワクチン及びその製造方法と応用 |
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Publication number | Publication date |
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KR100496249B1 (ko) | 2006-01-27 |
CN101121023A (zh) | 2008-02-13 |
TW589190B (en) | 2004-06-01 |
KR20000065256A (ko) | 2000-11-06 |
CA2261346C (en) | 2012-01-03 |
AU3699197A (en) | 1998-02-10 |
FR2751224B1 (fr) | 1998-11-20 |
DE69734284T2 (de) | 2006-07-13 |
US6207165B1 (en) | 2001-03-27 |
CN1225684A (zh) | 1999-08-11 |
HUP9903822A2 (hu) | 2000-03-28 |
DK0912743T3 (da) | 2006-01-30 |
RU2305559C2 (ru) | 2007-09-10 |
RU2002133052A (ru) | 2005-01-20 |
UA91675C2 (ru) | 2010-08-25 |
EP0912743B1 (fr) | 2005-09-28 |
HUP9903822A3 (en) | 2010-01-28 |
PL190615B1 (pl) | 2005-12-30 |
WO1998003658A1 (fr) | 1998-01-29 |
AU735291B2 (en) | 2001-07-05 |
FR2751224A1 (fr) | 1998-01-23 |
ES2251030T3 (es) | 2006-04-16 |
AR007864A1 (es) | 1999-11-24 |
PL331249A1 (en) | 1999-07-05 |
DE69734284D1 (de) | 2006-02-09 |
UA77935C2 (uk) | 2007-02-15 |
EP0912743A1 (fr) | 1999-05-06 |
CO4750676A1 (es) | 1999-03-31 |
BR9710740A (pt) | 1999-08-17 |
CN1329513C (zh) | 2007-08-01 |
US6576243B1 (en) | 2003-06-10 |
CA2261346A1 (en) | 1998-01-29 |
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