DK0912743T3 - Polynukleotidvaccinepræparat til behandling af luftvejs- og reproduktionssygdomme hos svin - Google Patents

Polynukleotidvaccinepræparat til behandling af luftvejs- og reproduktionssygdomme hos svin

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Publication number
DK0912743T3
DK0912743T3 DK97933745T DK97933745T DK0912743T3 DK 0912743 T3 DK0912743 T3 DK 0912743T3 DK 97933745 T DK97933745 T DK 97933745T DK 97933745 T DK97933745 T DK 97933745T DK 0912743 T3 DK0912743 T3 DK 0912743T3
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Prior art keywords
pigs
respiratory
treatment
vaccine preparation
polynucleotide vaccine
Prior art date
Application number
DK97933745T
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Danish (da)
English (en)
Inventor
Jean-Christophe Audonnet
Michel Riviere
Annabelle Bouchardon
Philippe Baudu
Original Assignee
Merial Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Merial Sas filed Critical Merial Sas
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Publication of DK0912743T3 publication Critical patent/DK0912743T3/da

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/107—Vibrio
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/23—Parvoviridae, e.g. feline panleukopenia virus
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    • A61K39/295—Polyvalent viral antigens; Mixtures of viral and bacterial antigens
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    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
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    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
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  • Health & Medical Sciences (AREA)
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  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Reproductive Health (AREA)
  • Physics & Mathematics (AREA)
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  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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DK97933745T 1996-07-19 1997-07-15 Polynukleotidvaccinepræparat til behandling af luftvejs- og reproduktionssygdomme hos svin DK0912743T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9609338A FR2751224B1 (fr) 1996-07-19 1996-07-19 Formule de vaccin polynucleotidique contre les pathologies respiratoires et de reproduction des porcs

Publications (1)

Publication Number Publication Date
DK0912743T3 true DK0912743T3 (da) 2006-01-30

Family

ID=9494450

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97933745T DK0912743T3 (da) 1996-07-19 1997-07-15 Polynukleotidvaccinepræparat til behandling af luftvejs- og reproduktionssygdomme hos svin

Country Status (20)

Country Link
US (2) US6207165B1 (ja)
EP (1) EP0912743B1 (ja)
JP (1) JP2001500111A (ja)
KR (1) KR100496249B1 (ja)
CN (2) CN101121023A (ja)
AR (1) AR007864A1 (ja)
AU (1) AU735291B2 (ja)
BR (1) BR9710740A (ja)
CA (1) CA2261346C (ja)
CO (1) CO4750676A1 (ja)
DE (1) DE69734284T2 (ja)
DK (1) DK0912743T3 (ja)
ES (1) ES2251030T3 (ja)
FR (1) FR2751224B1 (ja)
HU (1) HUP9903822A3 (ja)
PL (1) PL190615B1 (ja)
RU (1) RU2305559C2 (ja)
TW (1) TW589190B (ja)
UA (2) UA77935C2 (ja)
WO (1) WO1998003658A1 (ja)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU762901B2 (en) * 1996-07-19 2003-07-10 Merial Polynucleotide vaccine formula for treating porcine respiratory and reproductive diseases
EP0863151A1 (en) * 1997-02-12 1998-09-09 Akzo Nobel N.V. "Canine parvovirus dna vaccines"
CA2223029A1 (en) 1997-02-12 1998-08-12 Akzo Nobel Nv Canine parvovirus dna vaccines
US7211379B2 (en) * 1997-10-03 2007-05-01 Merial Sas Prevention of myocarditis, abortion and intrauterine infection associated with porcine circovirus-2
FR2781159B1 (fr) * 1998-07-06 2000-10-06 Merial Sas Vaccin circovirus et parvovirus porcin
US7192594B2 (en) * 1997-10-03 2007-03-20 Merial Limited Postweaning multisystemic wasting syndrome and porcine circovirus from pigs
FR2776294B1 (fr) * 1998-03-20 2001-06-22 Merial Sas Nouveaux circovirus porcins ; vaccins et reactifs de diagnostic
US6517843B1 (en) 1999-08-31 2003-02-11 Merial Reduction of porcine circovirus-2 viral load with inactivated PCV-2
FR2772047B1 (fr) 1997-12-05 2004-04-09 Ct Nat D Etudes Veterinaires E Sequence genomique et polypeptides de circovirus associe a la maladie de l'amaigrissement du porcelet (map), applications au diagnostic et a la prevention et/ou au traitement de l'infection
CA2313806A1 (en) * 1997-12-11 1999-06-17 University Of Saskatchewan Postweaning multisystemic wasting syndrome virus from pigs
ES2170622B1 (es) * 1999-12-03 2004-05-16 Consejo Superior De Investigaciones Cientificas Clones y vectores infectivos derivados de coronavirus y sus aplicaciones.
FR2804028B1 (fr) * 2000-01-21 2004-06-04 Merial Sas Vaccins adn ameliores pour animaux de rente
KR20030054139A (ko) * 2001-12-24 2003-07-02 학교법인 건국대학교 돼지 오제스키병 바이러스의 ｇＤ 유전자를 포함하는재조합 발현 벡터 및 이를 이용한 ＤＮＡ 백신
US7906311B2 (en) 2002-03-20 2011-03-15 Merial Limited Cotton rat lung cells for virus culture
US20060160759A1 (en) * 2002-09-28 2006-07-20 Jianzhu Chen Influenza therapeutic
EP1606419A1 (en) 2003-03-18 2005-12-21 Quantum Genetics Ireland Limited Systems and methods for improving protein and milk production of dairy herds
US7468273B2 (en) 2003-05-01 2008-12-23 Meial Limited Canine GHRH gene, polypeptides and methods of use
MXPA06005424A (es) 2003-11-13 2007-01-25 Univ Georgia Res Found Metodos para caracterizar virus de enfermedad bursal infecciosa.
US7527967B2 (en) * 2003-11-25 2009-05-05 Academia Sinica Recombinant baculovirus and virus-like particle
NZ549384A (en) 2004-02-19 2008-08-29 Univ Alberta Leptin promoter polymorphisms and uses thereof
RS51324B (sr) 2005-04-25 2010-12-31 Merial Ltd. Vakcine protiv nipah virusa
US20080241184A1 (en) 2005-08-25 2008-10-02 Jules Maarten Minke Canine influenza vaccines
US7771995B2 (en) 2005-11-14 2010-08-10 Merial Limited Plasmid encoding human BMP-7
JP2009515529A (ja) 2005-11-14 2009-04-16 メリアル リミテッド 腎不全のための遺伝子療法
US7862821B2 (en) 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
CA2684923C (en) 2007-05-02 2015-01-06 Merial Limited Dna plasmids having improved expression and stability
US20080274137A1 (en) * 2007-05-02 2008-11-06 Jean Christophe Francis Audonnet DNA plasmids having improved expression and stability
CA2744454C (en) 2008-11-28 2020-03-24 Merial Limited Recombinant avian influenza vaccine and uses thereof
JP5797636B2 (ja) 2009-04-03 2015-10-21 メリアル リミテッド ニューカッスル病ウイルスをベクターとするトリワクチン
PE20121685A1 (es) 2009-12-28 2012-12-28 Merial Ltd Antigeno ndv recombinante y usos del mismo
US20130197612A1 (en) 2010-02-26 2013-08-01 Jack W. Lasersohn Electromagnetic Radiation Therapy
EP2545067B1 (en) 2010-03-12 2016-11-30 Merial, Inc. Bluetongue virus recombinant vaccines and uses thereof
CN102373181B (zh) * 2010-08-09 2014-06-11 中山大学 猪流感病毒和猪蓝耳病病毒混合病毒样颗粒、制备方法和应用
CN102370976B (zh) * 2010-08-09 2014-06-11 中山大学 猪流感病毒和猪口蹄疫病毒的混合病毒样颗粒、制备方法和应用
CA2809127C (en) 2010-08-31 2019-04-02 Merial Limited Newcastle disease virus vectored herpesvirus vaccines
WO2012090073A2 (en) 2010-12-30 2012-07-05 The Netherlands Cancer Institute Methods and compositions for predicting chemotherapy sensitivity
EP2694678A2 (en) 2011-04-04 2014-02-12 Netherland Cancer Institute Methods and compositions for predicting resistance to anticancer treatment
EP2694677A2 (en) 2011-04-04 2014-02-12 Netherland Cancer Institute Methods and compositions for predicting resistance to anticancer treatment with protein kinase inhibitors
AU2012245395A1 (en) 2011-04-20 2013-11-14 Merial, Inc. Adjuvanted rabies vaccine with improved viscosity profile
WO2012149038A1 (en) 2011-04-25 2012-11-01 Advanced Bioscience Laboratories, Inc. Truncated hiv envelope proteins (env), methods and compositions related thereto
BR112013028605A2 (pt) 2011-05-07 2017-01-17 Avi Mex S A De C V Lab vetor viral, vacina recombinante contra prrs e uso de uma vacina
ES2764079T3 (es) 2011-05-27 2020-06-02 Boehringer Ingelheim Animal Health Usa Inc Vacunas genéticas contra el virus Hendra y el virus Nipah
US9592286B2 (en) * 2011-05-27 2017-03-14 Sinovet (Beijing) Biotechnology Co., Ltd. Combined vaccines for prevention of porcine virus infections
ES2674439T3 (es) 2011-06-01 2018-06-29 Merial, Inc. Administración sin aguja de vacunas contra el VSRRP
DK2741740T3 (en) 2011-08-12 2017-06-06 Merial Inc VACUUM-SUPPORTED CONSERVATION OF BIOLOGICAL PRODUCTS, IN PARTICULAR OF VACCINES
WO2013093629A2 (en) 2011-12-20 2013-06-27 Netherlands Cancer Institute Modular vaccines, methods and compositions related thereto
US9567606B2 (en) 2012-02-14 2017-02-14 Merial Inc. Recombinant poxviral vectors expressing both rabies and OX40 proteins, and vaccines made therefrom
LT2814508T (lt) 2012-02-14 2017-06-26 Merial, Inc. Rotaviruso subvieneto vakcinos jų gamybos būdai ir panaudojimas
WO2013138776A1 (en) 2012-03-16 2013-09-19 Merial Limited Novel methods for providing long-term protective immunity against rabies in animals, based upon administration of replication-deficient flavivirus expressing rabies g
MA37749B1 (fr) 2012-06-13 2017-05-31 Merial Ltd Vaccins contre les virus réassortis de la fièvre catarrhale et de la peste équine
CN102807989B (zh) * 2012-08-01 2014-04-23 中国人民解放军军事医学科学院军事兽医研究所 犬科和/或猫科动物疫病重组活载体疫苗的制备方法
US9556419B2 (en) 2013-03-12 2017-01-31 Merial Inc. Reverse genetics Schmallenberg virus vaccine compositions, and methods of use thereof
ES2762535T3 (es) * 2013-05-31 2020-05-25 Pulike Biological Eng Inc Virus de la pseudorrabia de los porcinos, composición de vacuna y método de preparación y uso de la misma
WO2015048115A1 (en) 2013-09-25 2015-04-02 Zoetis Llc Pcv2b divergent vaccine composition and methods of use
CN105251000B (zh) * 2014-09-30 2018-12-14 普莱柯生物工程股份有限公司 猪伪狂犬病病毒疫苗组合物及其制备方法和应用
MX2017005687A (es) 2014-11-03 2017-08-21 Merial Inc Metodos para usar formulaciones para vacuna con microagujas para elicitar en animales inmunidad protectora contra virus de la rabia.
CN107922462B (zh) 2015-06-23 2022-03-18 勃林格殷格翰动物保健美国公司 含prrsv次要蛋白的重组病毒载体及其制造方法与用途
CN105693827B (zh) * 2015-06-29 2020-05-15 普莱柯生物工程股份有限公司 一种猪伪狂犬病病毒亚单位疫苗及其制备方法和应用
CN104998256A (zh) * 2015-07-14 2015-10-28 天津瑞普生物技术股份有限公司 一种猪用三联灭活疫苗的制备方法
MA42653A (fr) 2015-08-20 2018-06-27 Merial Inc Vaccins recombinants contre le fcv et utilisations de ceux-ci
ES2974666T3 (es) 2015-09-29 2024-07-01 Boehringer Ingelheim Animal Health Usa Inc Vacunas de partículas similares a virus (VLP) del parvovirus canino (CPV) y usos de las mismas
MA49414A (fr) 2015-11-23 2020-04-22 Boehringer Ingelheim Animal Health Usa Inc Protéines de fusion de dmdv et e2 et leurs utilisations
TWI760322B (zh) 2016-01-29 2022-04-11 美商百靈佳殷格翰動物保健美國有限公司 重組腺病毒載體裝載之fmdv疫苗及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8901651A (nl) * 1989-06-29 1991-01-16 Centraal Diergeneeskundig Inst Vaccin tegen pestivirusinfecties, zoals varkenspest; daarvoor bruikbare nucleotidesequenties en polypeptiden.
US6592873B1 (en) * 1992-10-30 2003-07-15 Iowa State University Research Foundation, Inc. Polynucleic acids isolated from a porcine reproductive and respiratory syndrome virus (PRRSV) and proteins encoded by the polynucleic acids
DE69536091D1 (de) * 1994-01-27 2010-09-09 Univ Massachusetts Medical Immunisierung durch Impfung von DNS Transkriptionseinheit
US5516905A (en) * 1994-08-30 1996-05-14 University Of Massachusetts Medical Center Antibiotic compounds and methods to treat gram-positive bacterial and mycoplasmal infections
CA2216308A1 (en) * 1995-12-21 1997-07-03 Solvay (Societe Anonyme) Plasmid vaccine for pseudorabies virus

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JP2001500111A (ja) 2001-01-09
ES2251030T3 (es) 2006-04-16
CA2261346A1 (en) 1998-01-29
AR007864A1 (es) 1999-11-24
BR9710740A (pt) 1999-08-17
PL190615B1 (pl) 2005-12-30
US6207165B1 (en) 2001-03-27
FR2751224B1 (fr) 1998-11-20
DE69734284D1 (de) 2006-02-09
WO1998003658A1 (fr) 1998-01-29
UA77935C2 (uk) 2007-02-15
AU735291B2 (en) 2001-07-05
FR2751224A1 (fr) 1998-01-23
CN101121023A (zh) 2008-02-13
RU2002133052A (ru) 2005-01-20
CN1329513C (zh) 2007-08-01
TW589190B (en) 2004-06-01
HUP9903822A3 (en) 2010-01-28
KR100496249B1 (ko) 2006-01-27
KR20000065256A (ko) 2000-11-06
CN1225684A (zh) 1999-08-11
HUP9903822A2 (hu) 2000-03-28
PL331249A1 (en) 1999-07-05
EP0912743B1 (fr) 2005-09-28
DE69734284T2 (de) 2006-07-13
CA2261346C (en) 2012-01-03
AU3699197A (en) 1998-02-10
EP0912743A1 (fr) 1999-05-06
CO4750676A1 (es) 1999-03-31
UA91675C2 (ru) 2010-08-25
US6576243B1 (en) 2003-06-10
RU2305559C2 (ru) 2007-09-10

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