DK0807439T3 - Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne - Google Patents

Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne

Info

Publication number
DK0807439T3
DK0807439T3 DK97303204T DK97303204T DK0807439T3 DK 0807439 T3 DK0807439 T3 DK 0807439T3 DK 97303204 T DK97303204 T DK 97303204T DK 97303204 T DK97303204 T DK 97303204T DK 0807439 T3 DK0807439 T3 DK 0807439T3
Authority
DK
Denmark
Prior art keywords
adults
treatment
respiratory distress
distress syndrome
human chemokine
Prior art date
Application number
DK97303204T
Other languages
English (en)
Inventor
John Richard White
Louis Martin Pelus
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Application granted granted Critical
Publication of DK0807439T3 publication Critical patent/DK0807439T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/195—Chemokines, e.g. RANTES
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
    • A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Cephalosporin Compounds (AREA)
DK97303204T 1996-05-14 1997-05-12 Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne DK0807439T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1787196P 1996-05-14 1996-05-14

Publications (1)

Publication Number Publication Date
DK0807439T3 true DK0807439T3 (da) 2003-08-11

Family

ID=21785003

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97303204T DK0807439T3 (da) 1996-05-14 1997-05-12 Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne

Country Status (5)

Country Link
US (5) US6290948B1 (da)
EP (1) EP0807439B1 (da)
JP (2) JPH1053533A (da)
DE (1) DE69721120T2 (da)
DK (1) DK0807439T3 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6811773B1 (en) 1993-12-22 2004-11-02 Human Genome Sciences, Inc. Human monocyte colony inhibitory factor (M-CIF) polypeptides
US6488925B2 (en) 1993-12-22 2002-12-03 Human Genome Sciences, Inc. Macrophage inflammatory protein-4 (MIP-4) polypeptides
US6451562B1 (en) 1993-12-22 2002-09-17 Human Genome Sciences, Inc. Polypeptides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) polynucleotides
US6495129B1 (en) 1994-03-08 2002-12-17 Human Genome Sciences, Inc. Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3)
JPH11512610A (ja) * 1995-09-29 1999-11-02 スミスクライン・ビーチャム・コーポレイション 短縮形ケモカインβ−８
US6713052B1 (en) 1995-10-24 2004-03-30 Human Genome Sciences, Inc. Method of mobilizing stem cells with chemokine β-8
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10
US6632425B1 (en) 1997-03-20 2003-10-14 Human Genome Sciences, Inc. Chemokine compositions
US7067117B1 (en) 1997-09-11 2006-06-27 Cambridge University Technical Services, Ltd. Compounds and methods to inhibit or augment an inflammatory response
US6989435B2 (en) 1997-09-11 2006-01-24 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
KR19990042713A (ko) * 1997-11-27 1999-06-15 허일섭 사람에서 분리한 c 6 베타-케모카인 lkn-1의 cdna 및 재조합 lkn-1의 제조방법
AU1824499A (en) * 1997-12-30 1999-07-19 Chiron Corporation Human cxc chemokine ((tim-1))
EP1129193A4 (en) * 1998-11-10 2005-08-10 Human Genome Sciences Inc CHEMOKIN BETA-7
US7238711B1 (en) 1999-03-17 2007-07-03 Cambridge University Technical Services Ltd. Compounds and methods to inhibit or augment an inflammatory response
CA2431206C (en) * 2000-12-08 2009-09-01 Takeda Chemical Industries, Ltd. Combination drugs containing anti-sepsis cycloalkene compound
WO2005025593A2 (en) * 2003-05-09 2005-03-24 Schering Aktiengesellschaft Treatment of inflammatory respiratory diseases
MXPA05011886A (es) 2003-05-15 2006-02-17 Tanox Inc Metodos y composiciones para la prevencion y tratamiento de septicemia.
JP2008523083A (ja) * 2004-12-08 2008-07-03 イムノメディクス， インコーポレイテッド 炎症性疾患および免疫調節不全疾患、感染性疾患、病的血管新生およびがんの免疫療法および検出のための方法および組成物
JP5583575B2 (ja) 2007-03-28 2014-09-03 ユニベルシダード デ バルセロナ 感染症と関連炎症過程の治療のためのタンパク質生成物
CA2818548A1 (en) 2010-11-19 2012-05-24 Toshio Imai Neutralizing anti-ccl20 antibodies
EP3541407A1 (en) 2016-11-18 2019-09-25 Universitat de Barcelona Combined cd6 and imipenem therapy for treatment of infectious diseases and related inflammatory processes

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4897348A (en) * 1983-08-25 1990-01-30 Sri International Recombinant materials and methods for producing human connective tissue-activating peptide-III and analogs thereof
US4897338A (en) * 1987-08-03 1990-01-30 Allied-Signal Inc. Method for the manufacture of multilayer printed circuit boards
CH681625A5 (da) * 1988-12-08 1993-04-30 Sandoz Ag
US5212073A (en) * 1989-05-12 1993-05-18 Genetics Institute, Inc. Process for producing human JE cytokine
US5179078A (en) * 1989-05-12 1993-01-12 Dana Farber Cancer Institute Method of suppressing tumor formation in vivo
CA2064558C (en) * 1989-09-25 2001-01-30 Ian B. Pragnell Method for inhibiting growth of stem cells
NZ237202A (en) * 1990-02-23 1994-01-26 Bristol Myers Squibb Co Composition containing beta-lactam antibiotic and cationic oligopeptide
CA2091266A1 (en) * 1990-09-14 1992-03-15 Patricia Tekamp-Olson Expression of macrophage inducible proteins (mips) in yeast cells
US5401651A (en) * 1991-10-16 1995-03-28 Walz; Alfred DNA encoding ENA-78, a neutrophil activating factor
US5306709A (en) * 1991-11-15 1994-04-26 The University Of Pennsylvania Suppression of megakaryocytopoiesis by macrophage inflammatory proteins
US5346686A (en) * 1992-10-05 1994-09-13 Mallinckrodt Medical, Inc. Labelled interleukin-8 and medical uses thereof
US5413778A (en) * 1992-10-05 1995-05-09 The Regents Of The University Of Michigan Labelled monocyte chemoattractant protein material and medical uses thereof
US5474983A (en) * 1993-03-15 1995-12-12 The Research Foundation Of State University Of New York Method of inhibiting pro-inflammatory mediator release from basophils and mast cells
US5346685A (en) * 1993-04-23 1994-09-13 Mobil Oil Corp. Synthetic porous crystalline MCM-51, its synthesis and use
JPH0789866A (ja) * 1993-09-21 1995-04-04 Nippon Kayaku Co Ltd 感染防御剤
CN1143894A (zh) * 1993-12-22 1997-02-26 人类基因组科学公司 巨噬细胞炎性蛋白-3，-4和-1r
JPH10500301A (ja) * 1994-05-16 1998-01-13 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド マクロファージ遊走阻止因子−３
DE69433648T2 (de) * 1994-08-23 2005-02-17 Human Genome Sciences, Inc. Menschliche chemokin-polypeptide
NZ288799A (en) * 1994-08-23 1999-06-29 Human Genome Sciences Inc Human chemokine beta-9 polypeptides, polynucleotides encoding the chemokine and preparation thereof
AU3681795A (en) * 1994-09-23 1996-04-09 University Of Nebraska Board Of Regents Polypeptide agonists and antagonists of human interleukin-8
US5602008A (en) * 1994-11-29 1997-02-11 Incyte Pharmaceuticals, Inc. DNA encoding a liver expressed chemokine
CA2222280A1 (en) * 1995-06-05 1996-12-12 Human Genome Sciences, Inc. Human chemokine beta-11 and human chemokine alpha-1
MX9708528A (es) * 1995-06-06 1998-02-28 Human Genome Sciences Inc Quimiosina bata-13 humana.
AU2698795A (en) * 1995-06-06 1996-12-24 Human Genome Sciences, Inc. Human chemokine beta-12
ZA968896B (en) * 1995-10-24 1997-04-24 Smithkline Beecham Corp Method of mobilizing hematopoietic stem cells
DK0871664T3 (da) * 1995-10-24 2004-04-26 Smithkline Beecham Corp Mobilisering af bloddannende stamceller ved anvendelse af en chemokin
WO1997019173A1 (en) * 1995-11-21 1997-05-29 Smithkline Beecham Corporation Method of treating sepsis
AU5355996A (en) * 1996-02-23 1997-09-10 Human Genome Sciences, Inc. Human chemokine polypeptides
US6509313B1 (en) * 1996-02-28 2003-01-21 Cornell Research Foundation, Inc. Stimulation of immune response with low doses of cytokines
WO1997035027A1 (en) 1996-03-18 1997-09-25 Human Genome Sciences, Inc. Chemokine alpha 3
AU733925C (en) * 1996-03-27 2002-06-13 Icos Corporation Monocyte chemotactic protein-5 materials and methods
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10
GB9617923D0 (en) * 1996-08-28 1996-10-09 Smithkline Beecham Plc Novel receptor
AU4243097A (en) * 1996-09-10 1998-04-02 Schering Corporation Mammalian chemokines, related reagents
WO1998014573A1 (en) * 1996-09-30 1998-04-09 The General Hospital Corporation Mcp-4 and mcp-5: novel chemokines

Also Published As

Publication number Publication date
EP0807439B1 (en) 2003-04-23
US20020141972A1 (en) 2002-10-03
US6290948B1 (en) 2001-09-18
DE69721120D1 (de) 2003-05-28
JPH1053533A (ja) 1998-02-24
EP0807439A3 (en) 1998-03-11
US6406688B1 (en) 2002-06-18
US20020155094A1 (en) 2002-10-24
DE69721120T2 (de) 2003-12-04
US20020146390A1 (en) 2002-10-10
EP0807439A2 (en) 1997-11-19
JP2001122801A (ja) 2001-05-08

Similar Documents

Publication Publication Date Title
DK0807439T3 (da) Anvendelse af humant chemokin beta-9 til behandlingen af respiratorisk distresssyndrom hos voksne
DK0912743T3 (da) Polynukleotidvaccinepræparat til behandling af luftvejs- og reproduktionssygdomme hos svin
DE59709609D1 (de) Patientenuntersuchungstisch
CY2007001I2 (el) Φαρμακευτικο σκευασμα για χρηση στη θεραπεια του διαβητη
EE200100480A (et) Ksenoon kasutamiseks närvimürgistuste ravis
DE69721369D1 (de) Inhalator
DK0912194T3 (da) Polynucleotid-vaccineformulering, især til behandling af respiratorisk sygdom hos kvæg
DE69513438D1 (de) Absorbierender Wegwerfartikel
BR9506912A (pt) Artigo absorvente descartável
BR9509966A (pt) Artigo absorvente descartável
BR9503001A (pt) Artigo absorvente descartável
DE69715219D1 (de) Inhalator
DK19893A (da) Praeparat til nasal behandling
TR199901772T2 (da)
NO921652L (no) Keramisk skumlegeme, fremgangsmaate til dets fremstilling og anvendelse av legemet i en oljelense
EE03682B1 (et) Asendatud bensimidasooli derivaadid, protsessid nende valmistamiseks ning nende kasutamine
FI956298A7 (fi) 3-fenyyli-isokinolin-1(2H)-oneja, niiden valmistus ja terapeuttinen käyttö
NO991459D0 (no) Anvendelse av 1-hydroksy-2-pyridoner til behandling av hudinfeksjoner
BR9709826A (pt) Artigos absorventes respiráveis
IT1298689B1 (it) Dilatatore nasale perfezionato
IT233411Y1 (it) Pannolino assorbente regolabile in particolare per adulti
DE4499496T1 (de) Haltbarer Patientenstuhl
FR2752317B1 (fr) Terminal medical et paramedical
DK236489A (da) Anvendelse af diazepinoner til terapeutisk behandling af mikrokredsloebsforstyrrelser
KR970000336U (ko) 라면요리 2·3·4인용 전용냄비