FR2568248A1 - Nouveaux composes naphtaleniques, leur preparation et leur application comme medicaments - Google Patents

Nouveaux composes naphtaleniques, leur preparation et leur application comme medicaments Download PDF

Info

Publication number
FR2568248A1
FR2568248A1 FR8510988A FR8510988A FR2568248A1 FR 2568248 A1 FR2568248 A1 FR 2568248A1 FR 8510988 A FR8510988 A FR 8510988A FR 8510988 A FR8510988 A FR 8510988A FR 2568248 A1 FR2568248 A1 FR 2568248A1
Authority
FR
France
Prior art keywords
formula
compound
dimethyl
dimethylphenyl
ester
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
FR8510988A
Other languages
English (en)
French (fr)
Inventor
Paul Leroy Anderson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2568248A1 publication Critical patent/FR2568248A1/fr
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
    • C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
    • C07C57/40—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic containing condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/48—Unsaturated compounds containing hydroxy or O-metal groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/30—Oxygen atoms, e.g. delta-lactones
FR8510988A 1984-07-24 1985-07-16 Nouveaux composes naphtaleniques, leur preparation et leur application comme medicaments Pending FR2568248A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63380984A 1984-07-24 1984-07-24

Publications (1)

Publication Number Publication Date
FR2568248A1 true FR2568248A1 (fr) 1986-01-31

Family

ID=24541204

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8510988A Pending FR2568248A1 (fr) 1984-07-24 1985-07-16 Nouveaux composes naphtaleniques, leur preparation et leur application comme medicaments

Country Status (21)

Country Link
JP (1) JPS6137754A (it)
KR (1) KR860001045A (it)
AU (1) AU4522685A (it)
BE (1) BE902914A (it)
DE (1) DE3525256A1 (it)
DK (1) DK333785A (it)
ES (1) ES8705356A1 (it)
FI (1) FI852851L (it)
FR (1) FR2568248A1 (it)
GB (1) GB2162179A (it)
GR (1) GR851805B (it)
HU (1) HUT39142A (it)
IL (1) IL75874A0 (it)
IT (1) IT1200095B (it)
LU (1) LU86012A1 (it)
NL (1) NL8502010A (it)
PH (1) PH21444A (it)
PL (1) PL254654A1 (it)
PT (1) PT80845B (it)
SE (1) SE8503556L (it)
ZA (1) ZA855594B (it)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5091378A (en) * 1987-05-22 1992-02-25 E. R. Squibb & Sons, Inc. Phosphorus-containing HMG-CoA reductase inhibitors, new intermediates and method
US4904646A (en) * 1987-05-22 1990-02-27 E. R. Squibb & Sons, Inc. Phosphorus-containing HMG-COA reductase inhibitors
DE3722807A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Neue 3,5-dihydroxycarbonsaeuren und deren derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
US4792614A (en) * 1987-08-05 1988-12-20 American Home Products Corporation Substituted furans as inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
US4812583A (en) * 1987-09-11 1989-03-14 American Home Products Corporation Substituted acyloxyalkylphenylethylene inhibitors of 3-hydroxy-3-methylglutaryl-coa reductase
DE3818570A1 (de) * 1988-06-01 1989-12-21 Boehringer Mannheim Gmbh Neue 6-substituierte-4-hydroxy-tetrahydro-pyran -2-on-derivate, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen
US5506219A (en) * 1988-08-29 1996-04-09 E. R. Squibb & Sons, Inc. Pyridine anchors for HMG-CoA reductase inhibitors
CA2185961A1 (en) * 1996-09-19 1998-03-20 K.S. Keshava Murthy Process for producing simvastatin
US20010006644A1 (en) 1997-07-31 2001-07-05 David J. Bova Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
KR100836960B1 (ko) 2007-09-07 2008-06-10 주식회사 서울제약 새로운 나이아신 제어방출형 제제

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS55132595A (en) * 1979-04-04 1980-10-15 Nec Corp Semiconductor circuit

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Néant. *

Also Published As

Publication number Publication date
PH21444A (en) 1987-10-20
DK333785A (da) 1986-01-25
JPS6137754A (ja) 1986-02-22
PL254654A1 (en) 1986-08-26
PT80845B (en) 1987-03-24
GB2162179A (en) 1986-01-29
FI852851L (fi) 1986-01-25
FI852851A0 (fi) 1985-07-22
PT80845A (en) 1985-08-01
IL75874A0 (en) 1985-11-29
DE3525256A1 (de) 1986-01-30
AU4522685A (en) 1986-01-30
IT8548385A0 (it) 1985-07-23
NL8502010A (nl) 1986-02-17
SE8503556L (sv) 1986-01-25
SE8503556D0 (sv) 1985-07-22
BE902914A (fr) 1986-01-17
DK333785D0 (da) 1985-07-22
IT1200095B (it) 1989-01-05
GB8518490D0 (en) 1985-08-29
KR860001045A (ko) 1986-02-22
ZA855594B (en) 1987-02-25
HUT39142A (en) 1986-08-28
GR851805B (it) 1985-11-26
LU86012A1 (fr) 1986-02-12
ES545454A0 (es) 1987-05-01
ES8705356A1 (es) 1987-05-01

Similar Documents

Publication Publication Date Title
CH639974A5 (fr) Spiro-oxazolidine-diones.
EP0515541B1 (fr) PROCEDE DE PREPARATION DE L'ACIDE CIS-$g(b)-PHENYLGLYCIDIQUE-(2R,3R)
FR2553774A1 (fr) Analogues interphenylene de prostaglandines a substitution 7-oxabicycloheptane, utiles notamment comme agents cardiovasculaires
FR2568248A1 (fr) Nouveaux composes naphtaleniques, leur preparation et leur application comme medicaments
FR2554814A1 (fr) Oxazolidines, procede pour leur preparation et leurs utilisations therapeutiques, notamment dans le traitement de l'obesite et du diabete
EP0051917A1 (en) Benzofuran ethanolamine derivatives, processes for their preparation, and their use in medicine
EP0041410B1 (fr) Nouveaux éthers tricycliques, leurs procédés de préparation et leur utilisation comme médicament
CH680000A5 (it)
EP1525188B1 (fr) Derives de 4,4 -dithiobis- (3-aminobutane-1-sulfonates) nouveaux et compositions les contenant
EP1268397B1 (fr) Procede de preparation de la (2s,3r,4s)-4-hydroxyisoleucine et de ses analogues
CH643254A5 (fr) Analogues de la prostaglandine i(1) et compositions pharmaceutiques les contenant.
EP1651596B1 (fr) Derives de 4,4'-dithiobis-(3-aminobutane-1-sulfonates) nouveaux et compositions les contenant
CH637930A5 (fr) Analogues de la prostaglandine i(2) et compositions pharmaceutiques les contenant.
BE890948A (fr) Derives de l'acide anthranilique
BE1005612A5 (fr) Derive de la dichloroaniline.
FR2468587A1 (fr) Nouveau derive de la vitamine d3, ses utilisations therapeutiques, sa preparation et produits intermediaires de sa preparation
BE806848A (fr) Medicament a base d'un derive de la quinoleine
EP0105881A1 (fr) Nouvelles cyanoguanidines, leur procede d'obtention et les compositions pharmaceutiques en renfermant.
BE1001109A3 (fr) Nouvelles prostacyclines.
FR2475553A1 (fr) Nouvelles spiro(4h-2,3-dihydrobenzopyranne(4,5')-oxazolidine)-2'-ones, utiles comme intermediaires chimiques
FR2539412A1 (fr) Derives du 5-fluoruracile et leurs utilisations therapeutiques en tant qu'agents carcinostatiques
CH647503A5 (fr) Derives de la 16-methoxy-16-methyl-prostaglandine e(1), procede pour leur synthese et medicaments gastro-protecteurs contenant lesdits derives.
CA1073460A (fr) Composes chimiques utilisables comme analgesiques
FR2518998A1 (fr) Nouveaux derives heterocycliques d'acide acetique et procede pour leur preparation
FR2460945A2 (fr) Nouveaux derives d'acides 4h 1,3-benzodioxin-2-carboxyliques, un procede pour leur preparation et leur application comme medicaments