FR2497807B1 - - Google Patents

Info

Publication number
FR2497807B1
FR2497807B1 FR8100272A FR8100272A FR2497807B1 FR 2497807 B1 FR2497807 B1 FR 2497807B1 FR 8100272 A FR8100272 A FR 8100272A FR 8100272 A FR8100272 A FR 8100272A FR 2497807 B1 FR2497807 B1 FR 2497807B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR8100272A
Other languages
French (fr)
Other versions
FR2497807A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to ZA8231A priority Critical patent/ZA8231B/xx
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR8100272A priority patent/FR2497807A1/fr
Priority to HU813808A priority patent/HU185158B/hu
Priority to FI820042A priority patent/FI77872C/fi
Priority to JP57000638A priority patent/JPS57168000A/ja
Priority to DE8282400025T priority patent/DE3262580D1/de
Priority to AU79296/82A priority patent/AU550334B2/en
Priority to AT82400025T priority patent/ATE12239T1/de
Priority to PT74263A priority patent/PT74263A/pt
Priority to ES508588A priority patent/ES8305786A1/es
Priority to CA000393808A priority patent/CA1193246A/fr
Priority to EP83201391A priority patent/EP0110434B1/fr
Priority to US06/338,077 priority patent/US4386085A/en
Priority to EP82400025A priority patent/EP0057115B1/fr
Priority to AT83201391T priority patent/ATE23167T1/de
Priority to DE1999175073 priority patent/DE19975073I2/de
Priority to DE8383201391T priority patent/DE3273985D1/de
Priority to SU823378150A priority patent/SU1447289A3/ru
Priority to DK004082A priority patent/DK166680B1/da
Priority to IE44/82A priority patent/IE52595B1/en
Priority to IL6568082A priority patent/IL65680A/xx
Priority to US06/386,967 priority patent/US4447424A/en
Priority to KR8202614A priority patent/KR870001936B1/ko
Publication of FR2497807A1 publication Critical patent/FR2497807A1/fr
Priority to ES517764A priority patent/ES517764A0/es
Application granted granted Critical
Publication of FR2497807B1 publication Critical patent/FR2497807B1/fr
Priority to US06/614,440 priority patent/US4519946A/en
Priority to CA000468274A priority patent/CA1199907A/fr
Priority to US06/693,682 priority patent/US4634695A/en
Priority to AU51236/85A priority patent/AU579211B2/en
Priority to US06/810,316 priority patent/US4978657A/en
Priority to SG459/87A priority patent/SG45987G/en
Priority to FR8718376A priority patent/FR2625505B2/fr
Priority to JP1066488A priority patent/JPH01279897A/ja
Priority to US07/421,526 priority patent/US5043332A/en
Priority to GEAP19931370A priority patent/GEP19960479B/en
Priority to LTRP982A priority patent/LT2618B/xx
Priority to BG098505A priority patent/BG60768B2/bg
Priority to MD94-0265A priority patent/MD207C2/ro
Priority to NL300001C priority patent/NL300001I2/nl
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
    • C07J41/0016—Oximes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
    • C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/001—Oxiranes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8100272A 1981-01-09 1981-01-09 Nouveaux derives steroides substitues en 11b, leur proc ede de preparation et leur application comme medicament Granted FR2497807A1 (fr)

Priority Applications (38)

Application Number Priority Date Filing Date Title
ZA8231A ZA8231B (en) 1981-01-09 1981-01-05 New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
FR8100272A FR2497807A1 (fr) 1981-01-09 1981-01-09 Nouveaux derives steroides substitues en 11b, leur proc ede de preparation et leur application comme medicament
HU813808A HU185158B (en) 1981-01-09 1981-12-17 Process for the preparation of beta-substituted steroide derivatives
JP57000638A JPS57168000A (en) 1981-01-09 1982-01-07 Novel 11 beta position substituted steroid derivatives, manufacture, intermediates, use thereof and composition
FI820042A FI77872C (fi) 1981-01-09 1982-01-07 Foerfarande foer framstaellning av nya, terapeutiskt anvaendbara i 11 -staellning substituerade steroidderivat.
AT83201391T ATE23167T1 (de) 1981-01-09 1982-01-08 In stellung 11 substituierte steroidzwischenprodukte und verfahren zu ihrer herstellung.
AT82400025T ATE12239T1 (de) 1981-01-09 1982-01-08 In stellung 11-beta substituierte steroidderivate, verfahren zu ihrer herstellung, ihre anwendung als arzneimittel und zusammensetzungen, die sie enthalten.
PT74263A PT74263A (fr) 1981-01-09 1982-01-08 Procede de preparation de nouveaux derives steroides substitues en 11-beta
ES508588A ES8305786A1 (es) 1981-01-09 1982-01-08 "procedimiento de preparacion de nuevos derivados esteroides sustituidos en 11b".
CA000393808A CA1193246A (fr) 1981-01-09 1982-01-08 PROCEDE DE PREPARATION DE NOUVEAUX DERIVES STEROIDES SUBSTITUES EN 11 .beta.
EP83201391A EP0110434B1 (fr) 1981-01-09 1982-01-08 Nouveaux produits intermédiaires stéroides substitués en 11-beta et procédé de préparation de ces produits
US06/338,077 US4386085A (en) 1981-01-09 1982-01-08 Novel steroids
EP82400025A EP0057115B1 (fr) 1981-01-09 1982-01-08 Nouveaux dérivés stéroides substitués en 11beta, procédé de préparation, leur application comme médicament et les compositions les renfermant
AU79296/82A AU550334B2 (en) 1981-01-09 1982-01-08 1.-nor steroid derivatives substituted at 11beta position
DE1999175073 DE19975073I2 (de) 1981-01-09 1982-01-08 In Stellung 11-beta substituierte Steroidderivate,Verfahren zu ihrer Herstellung, ihre Anwendung als Arzneimittel und Zusammensetzungen, die sie enthalten.
DE8383201391T DE3273985D1 (en) 1981-01-09 1982-01-08 Steroid intermediates substituted at position 11, and process for their preparation
SU823378150A SU1447289A3 (ru) 1981-01-09 1982-01-08 Способ получени производных стероидов
DK004082A DK166680B1 (da) 1981-01-09 1982-01-08 Analogifremgangsmaade til fremstilling af 11beta-substituerede 4-umaettede steroider samt forbindelser til anvendelse som udgangsmateriale ved fremgangsmaaden
DE8282400025T DE3262580D1 (en) 1981-01-09 1982-01-08 Steroid derivatives substituted in the 11-beta position, process for their preparation, their utilization as medicaments and compositions containing them
IE44/82A IE52595B1 (en) 1981-01-09 1982-01-11 New steroid derivatives substituted at position 11beta,process and intermediates for preparing them,their use as medicaments and the compositions containing them
IL6568082A IL65680A (en) 1981-01-09 1982-05-04 11beta substituted steroids,process for preparing them,medicaments and compositions containing them
US06/386,967 US4447424A (en) 1981-01-09 1982-06-10 Steroid derivatives
KR8202614A KR870001936B1 (ko) 1981-01-09 1982-06-11 새로운 스테로이드 유도 체의 제조방법
ES517764A ES517764A0 (es) 1981-01-09 1982-11-29 Procedimiento de preparacion de nuevos derivados esteroides sustituidos en 11b.
US06/614,440 US4519946A (en) 1981-01-09 1984-05-25 Steroids
CA000468274A CA1199907A (fr) 1981-01-09 1984-11-20 PROCEDE POUR LA PREPARATION DE DERIVES DE STEROIDES HYDROXYLES EN 5.alpha., ET LES DERIVES AINSI OBTENUS
US06/693,682 US4634695A (en) 1981-01-09 1985-01-22 Steroid derivatives
AU51236/85A AU579211B2 (en) 1981-01-09 1985-12-12 Intermediate steroid products substituted at position 11 ` and processes for preparing them
US06/810,316 US4978657A (en) 1981-01-09 1985-12-17 Novel 11β-substituted-19-nor-steroids
SG459/87A SG45987G (en) 1981-01-09 1987-05-21 Steroid derivatives substituted in the 11-beta position, process for their preparation, their utilization as medicaments and compositions containing them
FR8718376A FR2625505B2 (fr) 1981-01-09 1987-12-30 Nouveaux derives steroides substitues en 11beta leur procede de preparation et leur application comme medicaments et les compositions pharmaceutiques les renfermant
JP1066488A JPH01279897A (ja) 1981-01-09 1989-03-20 新規な１１β位置換ステロイド誘導体の製造中間体
US07/421,526 US5043332A (en) 1981-01-09 1989-10-13 Novel 11β-substituted -19-nor-steriods
GEAP19931370A GEP19960479B (en) 1981-01-09 1993-07-31 Method of producing derivatives of steroids
LTRP982A LT2618B (lt) 1981-01-09 1993-09-16 Steroidu dariniu gavimo budas
BG098505A BG60768B2 (bg) 1981-01-09 1994-02-22 Производни на заместени стероиди в 11 бета,метод за получаването им,приложението им като лекарствени средства и състави,които ги съдържат
MD94-0265A MD207C2 (ro) 1981-01-09 1994-08-08 Procedeu de obţinere a derivaţilor steroizilor
NL300001C NL300001I2 (nl) 1981-01-09 2000-02-01 Nieuw, op de 11beta-plaats gesubstitueerde steroidederivaten, werkwijze voor de bereiding, hun toepassing als geneesmiddel en preparaten waarin ze zijn verwerkt.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8100272A FR2497807A1 (fr) 1981-01-09 1981-01-09 Nouveaux derives steroides substitues en 11b, leur proc ede de preparation et leur application comme medicament

Publications (2)

Publication Number Publication Date
FR2497807A1 FR2497807A1 (fr) 1982-07-16
FR2497807B1 true FR2497807B1 (US07678551-20100316-C00001.png) 1983-07-29

Family

ID=9253984

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8100272A Granted FR2497807A1 (fr) 1981-01-09 1981-01-09 Nouveaux derives steroides substitues en 11b, leur proc ede de preparation et leur application comme medicament

Country Status (22)

Country Link
US (4) US4386085A (US07678551-20100316-C00001.png)
EP (1) EP0057115B1 (US07678551-20100316-C00001.png)
JP (2) JPS57168000A (US07678551-20100316-C00001.png)
KR (1) KR870001936B1 (US07678551-20100316-C00001.png)
AU (2) AU550334B2 (US07678551-20100316-C00001.png)
BG (1) BG60768B2 (US07678551-20100316-C00001.png)
CA (1) CA1193246A (US07678551-20100316-C00001.png)
DE (2) DE3262580D1 (US07678551-20100316-C00001.png)
DK (1) DK166680B1 (US07678551-20100316-C00001.png)
ES (2) ES8305786A1 (US07678551-20100316-C00001.png)
FI (1) FI77872C (US07678551-20100316-C00001.png)
FR (1) FR2497807A1 (US07678551-20100316-C00001.png)
GE (1) GEP19960479B (US07678551-20100316-C00001.png)
HU (1) HU185158B (US07678551-20100316-C00001.png)
IE (1) IE52595B1 (US07678551-20100316-C00001.png)
LT (1) LT2618B (US07678551-20100316-C00001.png)
MD (1) MD207C2 (US07678551-20100316-C00001.png)
NL (1) NL300001I2 (US07678551-20100316-C00001.png)
PT (1) PT74263A (US07678551-20100316-C00001.png)
SG (1) SG45987G (US07678551-20100316-C00001.png)
SU (1) SU1447289A3 (US07678551-20100316-C00001.png)
ZA (1) ZA8231B (US07678551-20100316-C00001.png)

Families Citing this family (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4978657A (en) * 1981-01-09 1990-12-18 Roussel Uclaf Novel 11β-substituted-19-nor-steroids
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
FR2528434B1 (fr) * 1982-06-11 1985-07-19 Roussel Uclaf Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
FR2522328B1 (fr) * 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
FR2640977A2 (en) * 1982-06-11 1990-06-29 Roussel Uclaf New position-11 substituted 19-norsteroids and their application as medicinal products.
DE3231828A1 (de) * 1982-08-24 1984-03-01 Schering AG, 1000 Berlin und 4709 Bergkamen 17(alpha)-alkinyl-3,3-alkylendioxy-5(alpha),10(alpha)-epoxy-9(11)-estren-17(beta)-ol-derivate, verfahren zu deren herstellung und deren verwendung zur weiterverarbeitung
DE3231827A1 (de) * 1982-08-24 1984-03-01 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-17(alpha)-alkinyl-17ss-hydroxy-4,9(10)- estradien-3-on-derivate, deren herstellung und diese enthaltende pharmazeutische praeparate
EP0116974B1 (de) * 1983-02-18 1986-10-29 Schering Aktiengesellschaft 11-Beta-Aryl-Estradiene, Verfahren zu deren Herstellung und diese enthaltende pharmazeutische Präparate
DE3306121A1 (de) * 1983-02-18 1984-09-06 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-spirolaktone in der steroidreihe, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische praeparate
IL68222A (en) * 1983-03-24 1987-02-27 Yeda Res & Dev Contraceptive compositions comprising a progesterone antagonist and a blocker of progesterone activity
DE3320580A1 (de) * 1983-06-03 1984-12-06 Schering AG, 1000 Berlin und 4709 Bergkamen D-homo-4,9,16-estratriene, deren herstellung und diese enthaltende pharmazeutische praeparate
FR2549067B1 (fr) * 1983-06-14 1985-12-27 Roussel Uclaf Derives estradieniques radioactifs marques au tritium, leur procede de preparation et leur application pour l'etude et le dosage radio-immunologique de steroides dans les fluides biologiques
NO162241C (no) * 1983-06-14 1989-11-29 Roussel Uclaf Nye, radioaktive estradienderivater merket med jod125, fremgangsmaate ved deres fremstilling og deres anvendelse vedradioimmunologisk undersoekelse og mengdebestemmelse av steroider i biologiske vaesker.
FR2548192B1 (fr) * 1983-06-20 1985-11-22 Roussel Uclaf Derives estradieniques radioactifs marques a l'iode, leur procede de preparation et leur application aux dosages radioimmunologiques
ES8502612A1 (es) * 1983-06-15 1985-02-01 Schering Ag Procedimiento para la preparacion de 13a-alquilgonanos
DE3446661A1 (de) * 1984-12-18 1986-06-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 13(alpha)-alkyl-17(beta)-(3-acyloxypropyl)-gonane
IT1212835B (it) * 1983-08-18 1989-11-30 Lehner Ag Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
DE3337450A1 (de) * 1983-10-12 1985-04-25 Schering AG, 1000 Berlin und 4709 Bergkamen Prostaglandine und antigestagene fuer den schwangerschaftsabbruch
AU572589B2 (en) 1983-12-14 1988-05-12 Upjohn Company, The 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
DE3347126A1 (de) * 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
FR2566779B2 (fr) * 1984-06-29 1987-03-06 Roussel Uclaf Nouveaux derives steroides substitues en 11b, leur procede de preparation et leur application comme medicaments
US5116830A (en) * 1984-08-17 1992-05-26 Sri International Stereoisomerically pure 17α-ethynyl-estra-2-en-17β-ol and the 17β esters thereof, methods of preparation and uses
DE3438500C1 (de) * 1984-10-18 1986-05-28 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung 11ß-substituierter Δ↑9↑-19-Norsteroide
FR2573657B1 (fr) * 1984-11-29 1989-05-12 Roussel Uclaf Produit comprenant une substance antiprogestomimetique et une substance uterotonique
AU580843B2 (en) * 1985-02-07 1989-02-02 Schering Aktiengesellschaft 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them
DE3504421A1 (de) * 1985-02-07 1986-08-07 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 11ss-phenyl-gonane, deren herstellung und diese enthaltende pharmazeutische praeparate
DE3506785A1 (de) * 1985-02-22 1986-08-28 Schering AG, Berlin und Bergkamen, 1000 Berlin 11ss-n,n-dimethylaminophenyl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
GB8513723D0 (en) * 1985-05-31 1985-07-03 Erba Farmitalia 11-beta substituted steroids
DE3531903A1 (de) * 1985-09-05 1987-03-12 Schering Ag Oxytocin und antigestagen zur einleitung der geburt bzw. zum therapeutischen abbruch der graviditaet
DE3533175A1 (de) * 1985-09-13 1987-03-19 Schering Ag Antigestagene zur verschiebung der endometrialen reifung
FR2596395B1 (fr) * 1986-03-26 1989-05-26 Roussel Uclaf Nouveaux steroides comportant un cycle spirannique en position 17, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
FR2598421B1 (fr) * 1986-05-06 1988-08-19 Roussel Uclaf Nouveaux produits 19-nor ou 19-nor d-homo steroides substitues en position 11b par un radical phenyle portant un radical alkynyle, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
EP0254341B1 (en) * 1986-07-23 1990-01-03 Akzo N.V. Novel 18-phenyloestrane derivatives
DE3625315A1 (de) * 1986-07-25 1988-01-28 Schering Ag 11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate
US4774236A (en) * 1986-09-17 1988-09-27 Research Triangle Institute 17α-(substituted-methyl)-17β-hydroxy/esterified hydroxy steroids and pharmaceutical compositions containing them
US5272140A (en) * 1987-01-23 1993-12-21 Akzo N.V. 11-aryl steroid derivatives
IE60780B1 (en) * 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives
DE3708942A1 (de) * 1987-03-18 1988-09-29 Schering Ag 19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
US5446178A (en) * 1987-03-18 1995-08-29 Schering Aktiengesellschaft Process for preparing 19,11β-bridged steroids
ATE69820T1 (de) * 1987-04-24 1991-12-15 Akzo Nv 11-arylestranderivate und 11-arylpregnanderivate.
JPH085909B2 (ja) * 1987-07-24 1996-01-24 協和醗酵工業株式会社 Ｕｃｙ１００３誘導体
FR2618783B1 (fr) * 1987-07-30 1991-02-01 Roussel Uclaf Nouveaux 17-aryle steroides, leurs procedes et des intermediaires de preparation comme medicaments et les compositions pharmaceutiques les renfermant
US5319115A (en) * 1987-08-25 1994-06-07 Cocensys Inc. Method for making 3α-hydroxy, 3β-substituted-pregnanes
US5208227A (en) * 1987-08-25 1993-05-04 University Of Southern California Method, compositions, and compounds for modulating brain excitability
DE3878198T2 (de) * 1987-12-12 1993-06-24 Akzo Nv 11-arylsteroid-derivate.
BE1004905A4 (fr) * 1987-12-30 1993-02-23 Roussel Uclaf Nouveaux derives 17beta-oh 19-nor steroides substitues en 17alpha, leur procede de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant.
US4954490A (en) * 1988-06-23 1990-09-04 Research Triangle Institute 11 β-substituted progesterone analogs
DE3822770A1 (de) * 1988-07-01 1990-01-04 Schering Ag 13-alkyl-11ss-phenylgonane
DE3832303A1 (de) * 1988-09-20 1990-04-12 Schering Ag 11ss-phenyl-14ssh-steroide
FR2643638B1 (fr) * 1989-02-24 1991-06-14 Roussel Uclaf Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
DE3917274A1 (de) * 1989-05-24 1990-11-29 Schering Ag 9(alpha)-hydroxy-19, 11(beta)-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
DE3921059A1 (de) * 1989-06-23 1991-01-10 Schering Ag 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel
US5276023A (en) * 1989-08-08 1994-01-04 Roussel Uclaf 19-nor-steroid esters
FR2651435A1 (fr) * 1989-09-07 1991-03-08 Roussel Uclaf Nouvelle utilisation de composes anti-progestomimetiques.
FR2654337B1 (fr) * 1989-11-15 1994-08-05 Roussel Uclaf Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant.
FR2659233B1 (fr) * 1990-03-06 1994-01-21 Roussel Uclaf Nouvelle utilisation de composes anti-progestomimetiques chez les animaux d'elevage.
DE4018168A1 (de) * 1990-06-01 1991-12-05 Schering Ag Ausgangsverbindungen fuer die herstellung von 10ss-h-steroiden und ein verfahren zur herstellung dieser ausgangsverbindungen
US5407928A (en) * 1990-08-15 1995-04-18 Schering Aktiengesellschaft 11β-aryl-gona-4,9-dien-3-ones
JPH0464052U (US07678551-20100316-C00001.png) * 1990-10-05 1992-06-01
US5439913A (en) 1992-05-12 1995-08-08 Schering Aktiengesellschaft Contraception method using competitive progesterone antagonists and novel compounds useful therein
CA2100514C (en) * 1992-07-29 2005-03-29 Johannes A. M. Hamersma 17-spiromethylene steroids
AU1439595A (en) * 1993-12-22 1995-07-10 Salk Institute For Biological Studies, The Methods for reducing multidrug resistance
US5681817A (en) 1994-02-04 1997-10-28 The Medical College Of Hampton Roads Treatment of ovarian estrogen dependent conditions
FR2718354B1 (fr) * 1994-04-08 1996-05-03 Roussel Uclaf Application des composés antiglucocorticoïde pour la préparation de médicaments destinés à la prévention ou au traitement des manifestations liées au syndrome de sevrage des narcotiques et les compositions les renfermant.
DE4415590A1 (de) * 1994-04-28 1995-11-02 Schering Ag Verfahren zur stereoselektiven Einführung einer Alkinylseitenkette an 11ß-Aryl-substituierten 13alpha-Alkylgonan-17-onen
EP0683172B1 (en) * 1994-05-19 1997-08-13 Akzo Nobel N.V. 11,21-Bisphenyl-19-norpregnane derivatives
US5639598A (en) * 1994-05-19 1997-06-17 The Trustees Of The University Of Pennsylvania Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions
US5780220A (en) * 1994-05-19 1998-07-14 Trustees Of The University Of Pennsylvania Methods and compositions for inhibiting HIV replication
US5521166A (en) * 1994-12-19 1996-05-28 Ortho Pharmaceitical Corporation Antiprogestin cyclophasic hormonal regimen
ZA9510926B (en) 1994-12-23 1996-07-03 Schering Ag Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception
US5929262A (en) * 1995-03-30 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates
US5767113A (en) * 1995-05-10 1998-06-16 The Salk Institute For Biological Studies Compounds useful for concurrently activating glucocorticoid-induced response and reducing multidrug resistance
IL118974A (en) * 1995-08-17 2001-09-13 Akzo Nobel Nv History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
DK0900234T3 (da) 1996-05-01 2000-11-06 Us Gov Health & Human Serv 21-substituerede progesteronderivater anvendt som nye antigestagener
US6900193B1 (en) * 1996-05-01 2005-05-31 The United States Of America As Represented By The Department Of Health And Human Services Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
DE19706061A1 (de) * 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette
DE19745085A1 (de) * 1997-10-11 1999-04-15 Jenapharm Gmbh 11ß-Benzaldoxim-9alpha,10alpha-epoxy-estr-4-en-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
DE19809845A1 (de) * 1998-03-03 1999-09-09 Jenapharm Gmbh S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
US6020328A (en) * 1998-03-06 2000-02-01 Research Triangle Institute 20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
WO1999059596A1 (en) * 1998-05-15 1999-11-25 The Board Of Trustees Of Leland Stanford Junior University Glucocorticoid receptor antagonists for the treatment of dementia
ATE473759T1 (de) 1998-05-22 2010-07-15 Univ Leland Stanford Junior Bifunktionelle moleküle sowie darauf basierende therapien.
US5962444A (en) * 1998-05-29 1999-10-05 Research Triangle Institute 17β-nitro-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
US6262042B1 (en) * 1998-05-29 2001-07-17 Research Triangle Institute 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
AU4701299A (en) * 1998-06-23 2000-01-10 Stuart R. Adler Therapeutic applications of estrogenic carboxylic acids
US20020169205A1 (en) * 1998-09-29 2002-11-14 Krzysztof Chwalisz Implantation rates after in vitro fertilization, and treatment of infertility and early pregnancy loss with a nitric oxide donor or substrate alone or in combination with progesterone, and a method for contraception with nitric oxide inhibitors in combination with antiprogestins or other agents
CN1117759C (zh) * 1999-09-02 2003-08-13 上海中西药业股份有限公司 甾体化合物,其制备方法和其药物组合物及其应用
US20030013694A1 (en) * 2001-05-25 2003-01-16 Jens Hoffmann Use and compositions of antiprogestins for treatment of prostate diseases
FR2826004B1 (fr) * 2001-06-13 2008-03-28 Aventis Pharma Sa Procede de preparation de derives estrogenes
EP1285927A3 (de) 2001-08-16 2005-06-29 Schering Aktiengesellschaft Verwendung von Glucocorticoid-Rezeptorantagonisten zur Vorbeugung und Behandlung von Erkrankungen des männlichen Reproduktionssystems
US7326697B2 (en) 2002-04-29 2008-02-05 Corcept Therapeutics, Inc. Methods for increasing the therapeutic response to electroconvulsive therapy
DE10221034A1 (de) 2002-05-03 2003-11-20 Schering Ag 17alpha-Fluoralkyl-11ß-benzaldoxim-Steroide, Verfahren zu deren Herstellung, diese Steroide enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
US7250408B2 (en) 2002-12-16 2007-07-31 Bayer Schering Pharma Ag Glucocorticoid receptor antagonists for prophylaxis and therapy of glucocorticoid-mediated hypogonadism, of sexual dysfunction and/or infertility
FR2850022B1 (fr) * 2003-01-22 2006-09-08 Centre Nat Rech Scient Nouvelle utilisation de la mifepristone et de ses derives comme modulateurs de la voie de signalisation des proteines hedgehog et ses applications
AU2004217988C1 (en) * 2003-02-28 2010-06-03 Southwest Foundation For Biomedical Research Method for preparing 17 alpha-acetoxy-11beta-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione, intermediates thereof, and methods for the preparation of such intermediates
WO2004112720A2 (en) * 2003-06-20 2004-12-29 Viral Genomix, Inc. Antiviral compositions and methods of using the same
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
US20070105828A1 (en) * 2005-08-19 2007-05-10 Glenmark Pharmaceuticals Limited Novel polymorph form M of mifepristone and process for its preparation
US9062126B2 (en) 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
JP4382735B2 (ja) 2005-10-06 2009-12-16 独立行政法人科学技術振興機構 神経因性疼痛治療剤
DE102005059222B4 (de) * 2005-12-08 2007-10-11 Bayer Schering Pharma Ag 11ß-Benzaldoximderivate von D-Homoestra-4,9-dien-3-onen
PL1991559T3 (pl) * 2006-02-17 2012-11-30 Janssen Pharmaceutica Nv Pochodne oksy-steroidowe jako selektywne modulatory receptora progesteronu
US20070270393A1 (en) * 2006-02-17 2007-11-22 Theresa Buckley Methods and compositions for modulation of sleep cycle
DE102006018888A1 (de) * 2006-04-18 2007-10-25 Bayer Schering Pharma Ag Verfahren zur Herstellung von 4-[17beta-Methoxy-17alpha-methoxymethyl-3-oxoestra-4,9-dien-11beta-yl]benzaldehyd-(E)-oxims (Asoprisnil)
US9517240B2 (en) 2006-09-26 2016-12-13 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
WO2008039482A2 (en) * 2006-09-26 2008-04-03 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
SI3263112T1 (sl) 2006-10-24 2020-10-30 Allergan Pharmaceuticals International Limited Sestavki in metode za zaviranje endometrijskih proliferacij
JP2010516686A (ja) * 2007-01-17 2010-05-20 レプロス セラピューティクス インコーポレイティド ステロイド誘導体の安定性向上のための方法
HU228636B1 (en) * 2007-06-27 2013-04-29 Richter Gedeon Nyrt Industrial method for the synthesis of 17-acetoxy-11betha-4[-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione and the key intermediates of the process
TWI539953B (zh) 2008-04-28 2016-07-01 瑞波若斯治療學公司 用於治療乳癌之組成物和方法
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
WO2010129819A2 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
DE102009034367A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034362A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034368A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034366A1 (de) 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034525A1 (de) 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 (de) 2009-07-21 2011-02-10 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102010007719A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
DE102010007722A1 (de) 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
KR102166867B1 (ko) 2010-03-22 2020-10-19 앨러간 파마슈티컬스 인터내셔널 리미티드 항프로게스틴의 비독성 전달을 위한 조성물들과 그 방법들
WO2011150209A1 (en) 2010-05-26 2011-12-01 Corcept Therapeutics, Inc. Treatment of muscular dystrophy
DE102011004899A1 (de) 2011-03-01 2012-09-06 Bayer Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
US20130029953A1 (en) * 2011-07-28 2013-01-31 Klaus Nickisch Progesterone antagonists
EP2868320A1 (en) 2013-11-03 2015-05-06 Flamina Holding AG A composition or group of compositions for the treatment of human cells
WO2016140867A1 (en) 2015-03-02 2016-09-09 Corcept Therapeutics, Inc. Use of glucocorticoid receptor antagonist and somatostatin analogues to treat acth-secreting tumors
CA2978960C (en) 2015-03-30 2023-05-02 Corcept Therapeutics, Inc. Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency
US20180155388A1 (en) 2015-05-18 2018-06-07 Bayer Pharma Aktiengesellschaft Selective progesterone receptor modulator (sprm) regimen
ES2865334T3 (es) 2015-08-13 2021-10-15 Corcept Therapeutics Inc Método de diagnóstico diferencial de síndrome de Cushing dependiente de ACTH
CN108713023B (zh) 2015-12-23 2021-10-26 欧瑞克制药公司 糖皮质激素受体抑制剂
EP3394078A4 (en) * 2015-12-23 2019-11-27 Oric Pharmaceuticals, Inc. GLUCOCORTICOID RECEPTOR INHIBITORS
US11110103B2 (en) 2015-12-23 2021-09-07 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
SG11201806101SA (en) 2016-01-19 2018-08-30 Corcept Therapeutics Inc Differential diagnosis of ectopic cushing's syndrome
EP3214092A1 (en) 2016-03-04 2017-09-06 Bayer Pharma Aktiengesellschaft Prodrugs of the selective progesterone receptor modulator (sprm) (11.beta.,17.beta.)-17-hydroxy-11-[4-(methylsulphonyl)phenyl]-17-(pentafluoroethyl)estra-4,9-dien-3-one
PL3523315T3 (pl) * 2016-10-07 2021-10-18 Oric Pharmaceuticals, Inc. Inhibitor receptora glukokortykoidowego
EP3541394A1 (en) * 2016-11-17 2019-09-25 Cytoo Skeletal muscle hypertrophy inducers
MX2019011543A (es) 2017-03-31 2019-12-16 Corcept Therapeutics Inc Moduladores del receptor de glucocorticoides para el tratamiento de cancer cervical.
CA3065555A1 (en) 2017-06-20 2018-12-27 Corcept Therapeutics, Inc. Methods of treating neuroepithelial tumors using selective glucocorticoid receptor modulators
CN108070016B (zh) * 2017-12-29 2020-07-07 广西万德药业有限公司 甾体环氧异构体的循环利用方法
AU2020367769B2 (en) 2019-10-16 2023-10-12 Corcept Therapeutics Incorporated Method of normalizing the neutrophil to lymphocyte ratio in cancer patients with a selective glucocorticoid receptor antagonist
WO2021127376A1 (en) 2019-12-21 2021-06-24 Corcept Therapeutics Incorporated Treatment of, and differential diagnosis between, acth-dependent cushing's syndrome and acth-independent cushing's syndrome
JP2024500748A (ja) 2020-12-18 2024-01-10 インスティル バイオ （ユーケイ） リミテッド 腫瘍浸潤リンパ球の処理
KR20220149828A (ko) 2021-04-30 2022-11-09 삼성전자주식회사 반도체 소자
WO2023000135A1 (en) * 2021-07-19 2023-01-26 Context Biopharma Inc. Processes of making onapristone and intermediates thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3190796A (en) * 1963-04-25 1965-06-22 Upjohn Co Process for inhibiting the growth of micrococcus agilis with 11beta-hydroxy-11-(2-pyridylmethyl)-pregnane-3, 20-dione
FR2377417A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides substitues en 11b, ainsi que leur procede de preparation
FR2377418A1 (fr) * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments
US4197296A (en) * 1977-03-23 1980-04-08 Glaxo Group Limited Androstanes
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained

Also Published As

Publication number Publication date
ES508588A0 (es) 1983-04-16
US4447424A (en) 1984-05-08
US4386085A (en) 1983-05-31
GEP19960479B (en) 1996-07-22
DE19975073I2 (de) 2004-01-08
HU185158B (en) 1984-12-28
DK166680B1 (da) 1993-06-28
EP0057115A2 (fr) 1982-08-04
MD207C2 (ro) 1995-12-31
IE820044L (en) 1982-07-09
EP0057115B1 (fr) 1985-03-20
NL300001I2 (nl) 2000-08-01
JPH0466879B2 (US07678551-20100316-C00001.png) 1992-10-26
EP0057115A3 (en) 1982-09-29
FI820042L (fi) 1982-07-10
LT2618B (lt) 1994-04-25
JPH0234958B2 (US07678551-20100316-C00001.png) 1990-08-07
BG60768B2 (bg) 1996-02-29
AU550334B2 (en) 1986-03-20
AU7929682A (en) 1982-07-15
ES8305786A1 (es) 1983-04-16
FR2497807A1 (fr) 1982-07-16
ES8401498A1 (es) 1983-12-01
ZA8231B (en) 1982-11-24
DE3262580D1 (en) 1985-04-25
JPS57168000A (en) 1982-10-16
US4519946A (en) 1985-05-28
AU5123685A (en) 1986-04-17
IE52595B1 (en) 1987-12-23
NL300001I1 (nl) 2000-04-03
MD207B1 (ro) 1995-05-31
ES517764A0 (es) 1983-12-01
DE19975073I1 (de) 2000-03-09
SG45987G (en) 1987-11-13
KR840000581A (ko) 1984-02-25
US4634695A (en) 1987-01-06
SU1447289A3 (ru) 1988-12-23
KR870001936B1 (ko) 1987-10-22
PT74263A (fr) 1982-02-01
DK4082A (da) 1982-07-10
FI77872C (fi) 1989-05-10
JPH01279897A (ja) 1989-11-10
AU579211B2 (en) 1988-11-17
CA1193246A (fr) 1985-09-10
FI77872B (fi) 1989-01-31

Similar Documents

Publication Publication Date Title
FR2497807B1 (US07678551-20100316-C00001.png)
FR2498450B1 (US07678551-20100316-C00001.png)
FR2501436B1 (US07678551-20100316-C00001.png)
FR2500406B1 (US07678551-20100316-C00001.png)
FR2502622B1 (US07678551-20100316-C00001.png)
FR2504209B1 (US07678551-20100316-C00001.png)
FR2502155B1 (US07678551-20100316-C00001.png)
FR2501051B3 (US07678551-20100316-C00001.png)
FR2498637B1 (US07678551-20100316-C00001.png)
FR2500660B1 (US07678551-20100316-C00001.png)
FR2505422B1 (US07678551-20100316-C00001.png)
FR2503880B1 (US07678551-20100316-C00001.png)
FR2502423B1 (US07678551-20100316-C00001.png)
FR2502065B3 (US07678551-20100316-C00001.png)
FR2503689B1 (US07678551-20100316-C00001.png)
FR2504679B1 (US07678551-20100316-C00001.png)
FR2498418B3 (US07678551-20100316-C00001.png)
FR2502921B1 (US07678551-20100316-C00001.png)
FR2498597B1 (US07678551-20100316-C00001.png)
FR2500613B3 (US07678551-20100316-C00001.png)
FR2497987B1 (US07678551-20100316-C00001.png)
FR2502660B1 (US07678551-20100316-C00001.png)
FR2503164B1 (US07678551-20100316-C00001.png)
FR2504485B1 (US07678551-20100316-C00001.png)
FR2503587B1 (US07678551-20100316-C00001.png)

Legal Events

Date Code Title Description
TP Transmission of property