Patents

Search tools Text Classification Chemistry Measure Numbers Full documents Title Abstract Claims All Any Exact Not Add AND condition These CPCs and their children These exact CPCs Add AND condition
Exact Exact Batch Similar Substructure Substructure (SMARTS) Full documents Claims only Add AND condition Add AND condition
Application Numbers Publication Numbers Either Add AND condition

"procedimiento de preparacion de nuevos derivados esteroides sustituidos en 11b".

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS ESTEROIDES SUSTITUIDOS EN 11~J, DE FORMULA GENERAL (I), EN LA QUE R REPRESENTA UN RADICAL ORGANICO CON 1 A 18 ATOMOS DE CARBONO; R REPRESENTA UN RADICAL HIDROCARBURADO CON 1 A 8 ATOMOS DE CARBONO; X REPRESENTA EL RESTO DE UN ANILLO PENTAGONAL O EXAGONAL SUSTITUIDO; EL GRUPO C=A EN POSICION 3 REPRESENTA UN GRUPO OXO; Y B Y C FORMAN JUNTOS UN DOBLE ENLACE, Y SUS SALES DE ADICION DE ACIDOS FARMACEUTICAMENTE ACEPTABLES. CONSISTE EN SOMETER UN COMPUESTO DE FORMULA (II), EN LA QUE K REPRESENTA UN GRUPO CETONICO BLOQUEADO EN FORMA DE CETAL, DE DIOCETAL O DE METILOXIMA; Y R , R Y X TIENEN LOS SIGNIFICADOS YA INDICADOS, A LA ACCION DE UN AGENTE DE DESHIDRATACION, SUSCEPTIBLE DE LIBERAR LA FUNCION CETONA. DE APLICACION EN FARMACIA POR SU ACTIVIDAD ANTIGLUCOCORTICOIDE.

Classifications

C07J41/0016 Oximes
View 16 more classifications

Landscapes

Chemical & Material Sciences Organic Chemistry
Show more

ES8305786A1

Spain

Find Prior Art Similar
Other languages
English
Current Assignee
Sanofi Aventis France
Worldwide applications
1981 ZA FR HU 1982 JP FI ES EP CA AU DE SU DK PT DE US IE US KR ES 1984 US 1985 US AU 1987 SG 1989 JP 1993 GE LT 1994 BG MD 2000 NL
Application ES508588A events
1982-01-08
Application filed by Roussel Uclaf SA
1983-04-16
Publication of ES508588A0
1983-04-16
Publication of ES8305786A1
Status
Expired
Info
Patent citations (5)
Cited by (143)
Legal events
Similar documents
Priority and Related Applications
External links
Espacenet
Global Dossier
Discuss

Patent Citations (5)

Publication number Priority date Publication date Assignee Title
Family To Family Citations
US3190796A * 1963-04-25 1965-06-22 Upjohn Co Process for inhibiting the growth of micrococcus agilis with 11beta-hydroxy-11-(2-pyridylmethyl)-pregnane-3, 20-dione
FR2377417A1 * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides substitues en 11b, ainsi que leur procede de preparation
FR2377418A1 * 1977-01-13 1978-08-11 Roussel Uclaf Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments
US4197296A * 1977-03-23 1980-04-08 Glaxo Group Limited Androstanes
ZA8231B * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
* Cited by examiner, † Cited by third party

Cited By (143)

Publication number Priority date Publication date Assignee Title
Family To Family Citations
US4978657A * 1981-01-09 1990-12-18 Roussel Uclaf Novel 11β-substituted-19-nor-steroids
ZA8231B * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained
FR2528434B1 1982-06-11 1985-07-19 Roussel Uclaf Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament
FR2522328B1 * 1982-03-01 1986-02-14 Roussel Uclaf Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments
FR2640977A2 * 1982-06-11 1990-06-29 Roussel Uclaf New position-11 substituted 19-norsteroids and their application as medicinal products.
DE3231827A1 * 1982-08-24 1984-03-01 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-17(alpha)-alkinyl-17ss-hydroxy-4,9(10)- estradien-3-on-derivate, deren herstellung und diese enthaltende pharmazeutische praeparate
DE3231828A1 * 1982-08-24 1984-03-01 Schering AG, 1000 Berlin und 4709 Bergkamen 17(alpha)-alkinyl-3,3-alkylendioxy-5(alpha),10(alpha)-epoxy-9(11)-estren-17(beta)-ol-derivate, verfahren zu deren herstellung und deren verwendung zur weiterverarbeitung
DE3306121A1 * 1983-02-18 1984-09-06 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-spirolaktone in der steroidreihe, verfahren zu deren herstellung und diese verbindungen enthaltende pharmazeutische praeparate
DE3461090D1 * 1983-02-18 1986-12-04 Schering Ag 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them
IL68222A * 1983-03-24 1987-02-27 Yeda Res & Dev Contraceptive compositions comprising a progesterone antagonist and a blocker of progesterone activity
DE3320580A1 * 1983-06-03 1984-12-06 Schering AG, 1000 Berlin und 4709 Bergkamen D-homo-4,9,16-estratriene, deren herstellung und diese enthaltende pharmazeutische praeparate
FR2549067B1 * 1983-06-14 1985-12-27 Roussel Uclaf Derives estradieniques radioactifs marques au tritium, leur procede de preparation et leur application pour l'etude et le dosage radio-immunologique de steroides dans les fluides biologiques
FR2548192B1 * 1983-06-20 1985-11-22 Roussel Uclaf Derives estradieniques radioactifs marques a l'iode, leur procede de preparation et leur application aux dosages radioimmunologiques
NO162241C * 1983-06-14 1989-11-29 Roussel Uclaf Nye, radioaktive estradienderivater merket med jod125, fremgangsmaate ved deres fremstilling og deres anvendelse vedradioimmunologisk undersoekelse og mengdebestemmelse av steroider i biologiske vaesker.
DE3446661A1 * 1984-12-18 1986-06-19 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 13(alpha)-alkyl-17(beta)-(3-acyloxypropyl)-gonane
ES533260A0 * 1983-06-15 1985-02-01 Schering Ag Procedimiento para la preparacion de 13a-alquilgonanos
IT1212835B * 1983-08-18 1989-11-30 Lehner Ag Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
DE3337450A1 * 1983-10-12 1985-04-25 Schering AG, 1000 Berlin und 4709 Bergkamen Prostaglandine und antigestagene fuer den schwangerschaftsabbruch
AU572589B2 1983-12-14 1988-05-12 Upjohn Company, The 11(alpha)-difluoromethyl and (e)-and (z)-11-fluoromethylene steroids
DE3347126A1 * 1983-12-22 1985-07-11 Schering AG, 1000 Berlin und 4709 Bergkamen 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
FR2566779B2 * 1984-06-29 1987-03-06 Roussel Uclaf Nouveaux derives steroides substitues en 11b, leur procede de preparation et leur application comme medicaments
US5116830A * 1984-08-17 1992-05-26 Sri International Stereoisomerically pure 17α-ethynyl-estra-2-en-17β-ol and the 17β esters thereof, methods of preparation and uses
DE3438500C1 * 1984-10-18 1986-05-28 Schering AG, 1000 Berlin und 4709 Bergkamen Verfahren zur Herstellung 11ß-substituierter Δ↑9↑-19-Norsteroide
FR2573657B1 * 1984-11-29 1989-05-12 Roussel Uclaf Produit comprenant une substance antiprogestomimetique et une substance uterotonique
AU580843B2 * 1985-02-07 1989-02-02 Schering Aktiengesellschaft 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them
DE3504421A1 * 1985-02-07 1986-08-07 Schering AG, 1000 Berlin und 4709 Bergkamen Neue 11ss-phenyl-gonane, deren herstellung und diese enthaltende pharmazeutische praeparate
DE3506785A1 * 1985-02-22 1986-08-28 Schering AG, Berlin und Bergkamen, 1000 Berlin 11ss-n,n-dimethylaminophenyl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate
GB8513723D0 * 1985-05-31 1985-07-03 Erba Farmitalia 11-beta substituted steroids
DE3531903A1 * 1985-09-05 1987-03-12 Schering Ag Oxytocin und antigestagen zur einleitung der geburt bzw. zum therapeutischen abbruch der graviditaet
DE3533175A1 * 1985-09-13 1987-03-19 Schering Ag Antigestagene zur verschiebung der endometrialen reifung
FR2596395B1 * 1986-03-26 1989-05-26 Roussel Uclaf Nouveaux steroides comportant un cycle spirannique en position 17, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
FR2598421B1 * 1986-05-06 1988-08-19 Roussel Uclaf Nouveaux produits 19-nor ou 19-nor d-homo steroides substitues en position 11b par un radical phenyle portant un radical alkynyle, leur procede de preparation, leur application comme medicaments et les compositions les renfermant
EP0254341B1 * 1986-07-23 1990-01-03 Akzo N.V. Novel 18-phenyloestrane derivatives
DE3625315A1 * 1986-07-25 1988-01-28 Schering Ag 11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate
US4774236A * 1986-09-17 1988-09-27 Research Triangle Institute 17α-(substituted-methyl)-17β-hydroxy/esterified hydroxy steroids and pharmaceutical compositions containing them
US5272140A * 1987-01-23 1993-12-21 Akzo N.V. 11-aryl steroid derivatives
IE60780B1 * 1987-01-23 1994-08-10 Akzo Nv New 11-aryl steroid derivatives
US5446178A * 1987-03-18 1995-08-29 Schering Aktiengesellschaft Process for preparing 19,11β-bridged steroids
DE3708942A1 * 1987-03-18 1988-09-29 Schering Ag 19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
ES2045082T3 * 1987-04-24 1994-01-16 Akzo Nv Un metodo para la preparacion de nuevos derivados 11-arilestrano y 11-arilpregnano.
JPH085909B2 * 1987-07-24 1996-01-24 協和醗酵工業株式会社 Ｕｃｙ１００３誘導体
FR2618783B1 * 1987-07-30 1991-02-01 Roussel Uclaf Nouveaux 17-aryle steroides, leurs procedes et des intermediaires de preparation comme medicaments et les compositions pharmaceutiques les renfermant
US5319115A * 1987-08-25 1994-06-07 Cocensys Inc. Method for making 3α-hydroxy, 3β-substituted-pregnanes
US5208227A * 1987-08-25 1993-05-04 University Of Southern California Method, compositions, and compounds for modulating brain excitability
ATE85342T1 * 1987-12-12 1993-02-15 Akzo Nv 11-arylsteroid-derivate.
JP2785023B2 * 1987-12-30 1998-08-13 ルセル―ユクラフ １７α位置を置換された１７β―ＯＨ―１９―ノルステロイドの新誘導体、その製造方法、その薬剤としての使用及びそれを含有する製薬組成物
US4954490A * 1988-06-23 1990-09-04 Research Triangle Institute 11 β-substituted progesterone analogs
DE3822770A1 * 1988-07-01 1990-01-04 Schering Ag 13-alkyl-11ss-phenylgonane
DE3832303A1 * 1988-09-20 1990-04-12 Schering Ag 11ss-phenyl-14ssh-steroide
FR2643638B1 * 1989-02-24 1991-06-14 Roussel Uclaf Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
DE3917274A1 * 1989-05-24 1990-11-29 Schering Ag 9(alpha)-hydroxy-19, 11(beta)-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate
DE3921059A1 * 1989-06-23 1991-01-10 Schering Ag 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel
US5276023A * 1989-08-08 1994-01-04 Roussel Uclaf 19-nor-steroid esters
FR2651435A1 * 1989-09-07 1991-03-08 Roussel Uclaf Nouvelle utilisation de composes anti-progestomimetiques.
FR2654337B1 * 1989-11-15 1994-08-05 Roussel Uclaf Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant.
FR2659233B1 * 1990-03-06 1994-01-21 Roussel Uclaf Nouvelle utilisation de composes anti-progestomimetiques chez les animaux d'elevage.
DE4018168A1 * 1990-06-01 1991-12-05 Schering Ag Ausgangsverbindungen fuer die herstellung von 10ss-h-steroiden und ein verfahren zur herstellung dieser ausgangsverbindungen
US5407928A * 1990-08-15 1995-04-18 Schering Aktiengesellschaft 11β-aryl-gona-4,9-dien-3-ones
JPH0464052U * 1990-10-05 1992-06-01
US5439913A 1992-05-12 1995-08-08 Schering Aktiengesellschaft Contraception method using competitive progesterone antagonists and novel compounds useful therein
CA2100514C * 1992-07-29 2005-03-29 Johannes A. M. Hamersma 17-spiromethylene steroids
AU1439595A * 1993-12-22 1995-07-10 Salk Institute For Biological Studies, The Methods for reducing multidrug resistance
US5681817A 1994-02-04 1997-10-28 The Medical College Of Hampton Roads Treatment of ovarian estrogen dependent conditions
FR2718354B1 * 1994-04-08 1996-05-03 Roussel Uclaf Application des composés antiglucocorticoïde pour la préparation de médicaments destinés à la prévention ou au traitement des manifestations liées au syndrome de sevrage des narcotiques et les compositions les renfermant.
DE4415590A1 * 1994-04-28 1995-11-02 Schering Ag Verfahren zur stereoselektiven Einführung einer Alkinylseitenkette an 11ß-Aryl-substituierten 13alpha-Alkylgonan-17-onen
EP0683172B1 * 1994-05-19 1997-08-13 Akzo Nobel N.V. 11,21-Bisphenyl-19-norpregnane derivatives
US5780220A * 1994-05-19 1998-07-14 Trustees Of The University Of Pennsylvania Methods and compositions for inhibiting HIV replication
US5639598A * 1994-05-19 1997-06-17 The Trustees Of The University Of Pennsylvania Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions
US5521166A * 1994-12-19 1996-05-28 Ortho Pharmaceitical Corporation Antiprogestin cyclophasic hormonal regimen
ZA9510926B 1994-12-23 1996-07-03 Schering Ag Compounds with progesterone-antagonistic and antiestrogenic action to be used together for female contraception
US5929262A * 1995-03-30 1999-07-27 The United States Of America As Represented By The Department Of Health And Human Services Method for preparing 17α-acetoxy-11β-(4-N, N-dimethylaminophyl)-19-Norpregna-4,9-diene-3, 20-dione, intermediates useful in the method, and methods for the preparation of such intermediates
US5767113A * 1995-05-10 1998-06-16 The Salk Institute For Biological Studies Compounds useful for concurrently activating glucocorticoid-induced response and reducing multidrug resistance
IL118974A * 1995-08-17 2001-09-13 Akzo Nobel Nv History 11 - (Transformed Phenyl) - Astra - 4, 9 - Diane, their preparation and pharmaceutical preparations containing them
US6900193B1 * 1996-05-01 2005-05-31 The United States Of America As Represented By The Department Of Health And Human Services Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
US6861415B2 1996-05-01 2005-03-01 The United States Of America As Represented By The Department Of Health And Human Services 21-substituted progesterone derivatives as new antiprogestational agents
DE19706061A1 * 1997-02-07 1998-08-13 Schering Ag Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette
DE19745085A1 * 1997-10-11 1999-04-15 Jenapharm Gmbh 11ß-Benzaldoxim-9alpha,10alpha-epoxy-estr-4-en-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate
DE19809845A1 * 1998-03-03 1999-09-09 Jenapharm Gmbh S-substituierte 11beta-Benzaldoxim-estra-4,9-dien-kohlensäurethiolester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
US6020328A * 1998-03-06 2000-02-01 Research Triangle Institute 20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
EP1076562B1 * 1998-05-15 2006-02-15 The Board Of Trustees Of The Leland Stanford Junior University Glucocorticoid receptor antagonists for the treatment of dementia
DE69942578D1 1998-05-22 2010-08-26 Univ R Bifunktionelle moleküle sowie darauf basierende therapien.
US5962444A * 1998-05-29 1999-10-05 Research Triangle Institute 17β-nitro-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
US6262042B1 1998-05-29 2001-07-17 Research Triangle Institute 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties
WO1999066915A2 1998-06-23 1999-12-29 Southern Illinois University At Carbondale Therapeutic applications of estrogenic carboxylic acids
US20020169205A1 * 1998-09-29 2002-11-14 Krzysztof Chwalisz Implantation rates after in vitro fertilization, and treatment of infertility and early pregnancy loss with a nitric oxide donor or substrate alone or in combination with progesterone, and a method for contraception with nitric oxide inhibitors in combination with antiprogestins or other agents
CN1117759C * 1999-09-02 2003-08-13 上海中西药业股份有限公司 甾体化合物,其制备方法和其药物组合物及其应用
US20030013694A1 * 2001-05-25 2003-01-16 Jens Hoffmann Use and compositions of antiprogestins for treatment of prostate diseases
FR2826004B1 * 2001-06-13 2008-03-28 Aventis Pharma Sa Procede de preparation de derives estrogenes
EP1285927A3 2001-08-16 2005-06-29 Schering Aktiengesellschaft Verwendung von Glucocorticoid-Rezeptorantagonisten zur Vorbeugung und Behandlung von Erkrankungen des männlichen Reproduktionssystems
US7326697B2 2002-04-29 2008-02-05 Corcept Therapeutics, Inc. Methods for increasing the therapeutic response to electroconvulsive therapy
DE10221034A1 2002-05-03 2003-11-20 Schering Ag 17alpha-Fluoralkyl-11ß-benzaldoxim-Steroide, Verfahren zu deren Herstellung, diese Steroide enthaltende pharmazeutische Präparate sowie deren Verwendung zur Herstellung von Arzneimitteln
US7250408B2 2002-12-16 2007-07-31 Bayer Schering Pharma Ag Glucocorticoid receptor antagonists for prophylaxis and therapy of glucocorticoid-mediated hypogonadism, of sexual dysfunction and/or infertility
FR2850022B1 * 2003-01-22 2006-09-08 Centre Nat Rech Scient Nouvelle utilisation de la mifepristone et de ses derives comme modulateurs de la voie de signalisation des proteines hedgehog et ses applications
AU2004217988C1 * 2003-02-28 2010-06-03 Southwest Foundation For Biomedical Research Method for preparing 17 alpha-acetoxy-11beta-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione, intermediates thereof, and methods for the preparation of such intermediates
WO2004112720A2 * 2003-06-20 2004-12-29 Viral Genomix, Inc. Antiviral compositions and methods of using the same
DK1889198T3 2005-04-28 2015-02-09 Proteus Digital Health Inc Farma-informatiksystem
US20070105828A1 * 2005-08-19 2007-05-10 Glenmark Pharmaceuticals Limited Novel polymorph form M of mifepristone and process for its preparation
US9062126B2 2005-09-16 2015-06-23 Raptor Pharmaceuticals Inc. Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof
JP4382735B2 2005-10-06 2009-12-16 独立行政法人科学技術振興機構 神経因性疼痛治療剤
DE102005059222B4 * 2005-12-08 2007-10-11 Bayer Schering Pharma Ag 11ß-Benzaldoximderivate von D-Homoestra-4,9-dien-3-onen
US20070270393A1 * 2006-02-17 2007-11-22 Theresa Buckley Methods and compositions for modulation of sleep cycle
PT1991559E * 2006-02-17 2012-09-06 Janssen Pharmaceutica Nv Derivados de oxa-esteróides como moduladores selectivos de receptor de progesterona
DE102006018888A1 * 2006-04-18 2007-10-25 Bayer Schering Pharma Ag Verfahren zur Herstellung von 4-[17beta-Methoxy-17alpha-methoxymethyl-3-oxoestra-4,9-dien-11beta-yl]benzaldehyd-(E)-oxims (Asoprisnil)
US9517240B2 2006-09-26 2016-12-13 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
WO2008039482A2 * 2006-09-26 2008-04-03 The Regents Of The University Of California Methods and compositions for cancer prevention and treatment
LT2078032T 2006-10-24 2017-11-10 Repros Therapeutics Inc. Kompozicijos ir būdai, skirti gimdos gleivinės proliferacijos slopinimui
KR20090105944A * 2007-01-17 2009-10-07 레프로스 쎄라피우틱스 아이엔씨. 11-(4-아미노페닐)-19-노르프레그나-4,9(10)-디엔-3,20-디온 유도체의 약학적으로 허용가능한 염
HU228636B1 * 2007-06-27 2013-04-29 Richter Gedeon Nyrt Industrial method for the synthesis of 17-acetoxy-11betha-4[-(dimethylamino)-phenyl]-21-methoxy-19-norpregna-4,9-dien-3,20-dione and the key intermediates of the process
TWI539953B 2008-04-28 2016-07-01 瑞波若斯治療學公司 用於治療乳癌之組成物和方法
AU2010216512B2 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
MY163048A 2009-05-06 2017-08-15 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
DE102009034362A1 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034368A1 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034366A1 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034367A1 2009-07-20 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102009034525A1 2009-07-21 2011-01-27 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
DE102009034526A1 2009-07-21 2011-02-10 Bayer Schering Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten
DE102010007719A1 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
DE102010007722A1 2010-02-10 2011-08-11 Bayer Schering Pharma Aktiengesellschaft, 13353 Progesteronrezeptorantagonisten
CN102906103A 2010-03-22 2013-01-30 利普生物药剂公司 用于抗孕酮的非毒性递送的组合物和方法
US11103514B2 2010-05-26 2021-08-31 Corcept Therapeutics, Inc. Treatment of muscular dystrophy
DE102011004899A1 2011-03-01 2012-09-06 Bayer Pharma Aktiengesellschaft 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten
US20130029953A1 * 2011-07-28 2013-01-31 Klaus Nickisch Progesterone antagonists
EP2868320A1 2013-11-03 2015-05-06 Flamina Holding AG A composition or group of compositions for the treatment of human cells
CA2977591A1 2015-03-02 2016-09-09 Corcept Therapeutics, Inc. Use of glucocorticoid receptor antagonist and somatostatin analogues to treat acth-secreting tumors
ES2906778T3 2015-03-30 2022-04-20 Corcept Therapeutics Inc Uso de antagonistas del receptor de glucocorticoides en combinación con glucocorticoides para tratar la insuficiencia suprarrenal
EP3417863A1 2015-05-18 2018-12-26 Bayer Pharma Aktiengesellschaft Selective progesterone receptor modulator (sprm) for use in the treatment of heavy menstrual bleeding
JP6768789B2 2015-08-13 2020-10-14 コーセプト セラピューティクス， インコーポレイテッド Ａｃｔｈ依存性クッシング症候群を鑑別診断する方法
US11110103B2 2015-12-23 2021-09-07 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
WO2017112902A1 2015-12-23 2017-06-29 Oric Pharmaceuticals, Inc. Inhibitors of glucocorticoid receptor
JP6995757B2 2015-12-23 2022-01-17 オリック ファーマシューティカルズ，インク． グルココルチコイド受容体の阻害剤
ES2861524T3 2016-01-19 2021-10-06 Corcept Therapeutics Inc Diagnóstico diferencial del Síndrome de Cushing Ectópico
EP3214092A1 2016-03-04 2017-09-06 Bayer Pharma Aktiengesellschaft Prodrugs of the selective progesterone receptor modulator (sprm) (11.beta.,17.beta.)-17-hydroxy-11-[4-(methylsulphonyl)phenyl]-17-(pentafluoroethyl)estra-4,9-dien-3-one
CN110099915A * 2016-10-07 2019-08-06 欧瑞克制药公司 糖皮质激素受体抑制剂
CN110099688A * 2016-11-17 2019-08-06 赛途公司 骨骼肌肥大诱导物
JP7563882B2 2017-03-31 2024-10-08 コーセプト セラピューティクス， インコーポレイテッド 子宮頸がんを処置するためのグルココルチコイドレセプターモジュレーター
JP2020524152A 2017-06-20 2020-08-13 コーセプト セラピューティクス， インコーポレイテッド 選択的グルココルチコイドレセプターモジュレーターを使用して神経上皮腫瘍を処置する方法
CN108070016B * 2017-12-29 2020-07-07 广西万德药业有限公司 甾体环氧异构体的循环利用方法
JP7629913B2 2019-10-16 2025-02-14 コーセプト セラピューティクス， インコーポレイテッド 選択的グルココルチコイド受容体拮抗物質を用いてがん患者における好中球／リンパ球比を正常化する方法
WO2021127376A1 2019-12-21 2021-06-24 Corcept Therapeutics Incorporated Treatment of, and differential diagnosis between, acth-dependent cushing's syndrome and acth-independent cushing's syndrome
CA3205462A1 2020-12-18 2022-06-23 Instil Bio (Uk) Limited Processing of tumor infiltrating lymphocytes
KR20220149828A 2021-04-30 2022-11-09 삼성전자주식회사 반도체 소자
WO2023000135A1 * 2021-07-19 2023-01-26 Context Biopharma Inc. Processes of making onapristone and intermediates thereof
* Cited by examiner, † Cited by third party, ‡ Family to family citation

Similar Documents

Publication Publication Date Title
ES8401498A1 1983-12-01 Procedimiento de preparacion de nuevos derivados esteroides sustituidos en 11b.
DE3367396D1 1986-12-11 19-nor steroids substituted at position 11 and optionally at position 2, their preparation, their utilization as medicaments, compositions containing them and intermediates obtained
ES486990A1 1980-10-01 Un procedimiento para la preparacion de un derivado de car- boestirilo
AU666916B2 1996-02-29 Novel 19-nor steroids having a thiocarbon-containing chain in the 11beta position, a method for preparing same and intermediates therefor, medicinal uses thereof and compositions containing said steroids
ES473817A1 1979-04-16 Procedimiento para preparar derivados de piperazina.
GB1461209A 1977-01-13 Thienyl and thietyl compounds
ZA881030B 1989-04-26 19-nor steroids substituted in position 7,their preparation,application as medicaments,compositions containing them
HU9401427D0 1994-08-29 19-nor steroide derivatives, process for producing them and compositions containing them
ZA793453B 1980-06-25 New 3,20-dioxo-4,9-diene-21-hydroxyl steroid derivatives,a process for preparing them,their use as medicaments and the pharmaceutical compositions containing them
ES8207180A1 1982-09-01 Procedimiento de fabricacion de derivados de tetrahidro-5,67,7a 4h-tieno (3,2-c) piridinona-2 .
DE3372095D1 1987-07-23 Novel phenylpiperazine derivatives and process for producing the same
ES8701174A1 1986-11-16 Un metodo de preparacion de un compuesto de tiadiazina
ZA836090B 1985-04-24 Thieno-thiazole derivatives,processes for preparing these compounds,and pharmaceutical compositions thereof
IE780077L 1978-07-13 11-beta-substituted steroids
GB1515017A 1978-06-21 2',3'-dihydroestra-1,3,5(10)-trieno-(16alpha,17alpha-b)furan-17beta-ols
ES8401957A1 1984-01-01 Procedimiento de preparacion de derivados del acido 2-tiofen-acetico.
DE3160232D1 1983-06-16 Novel 17-amino-16-hydroxy steroids of the androstane and oestrane series and derivatives thereof, processes for their preparation and pharmaceutical compositions
GB1514621A 1978-06-14 13-ethynyl-and 13-(2-halovinyl)-steroids and their preparation
ES8102110A1 1980-12-16 Procedimiento para la preparacion de acido 1,2,3-tiadiazol- 5-il-tioglicolico
GB1522894A 1978-08-31 Anti-sunburn compositions containing 2-phenyl-indole derivatives
JPS5448770A 1979-04-17 5-alkoxypicolinic acid ester, its preparation and hypotensive agent containing the same
GB1074468A 1967-07-05 Carbalkoxyhtdrazones of the androstane adn estrane series
IE780933L 1978-11-06 Pregnene derivatives
IE41112L 1975-10-17 Furyl compounds
JPS5430147A 1979-03-06 Prostaglandin i, analogues and their preparation

Priority And Related Applications

Applications Claiming Priority (1)

Application Filing date Title
FR8100272A 1981-01-09 Nouveaux derives steroides substitues en 11b, leur proc ede de preparation et leur application comme medicament

Legal Events

Date Code Title Description
2007-12-16 FD1A Patent lapsed

Effective date: 20030210
Data provided by IFI CLAIMS Patent Services